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Full-Text Articles in Physics
A Biosynthetic Membrane-Anchor/Protein System Based On A Genetically Encoded "Aldehyde Tag", Chaojie Zhen
A Biosynthetic Membrane-Anchor/Protein System Based On A Genetically Encoded "Aldehyde Tag", Chaojie Zhen
Honors Capstone Projects - All
Lipid membranes or bilayers serve as barriers for the cell and its organelles. A distinguishing feature of cellular function is the ability to monitor and process the biochemical information between the cells’ intra and extracellular environments in order to maintain the homeostatic reactions that are essential to life. Surface membrane proteins play a key role in mediating this information exchange by functionalizing the bilayer. As a result of their importance in living systems, proteins are integrated into biomimetic membrane systems to replicate their natural functions in biomedical technologies. Current protein integration methods are limited by the selection of commercially available …
Spiral Patterns In Liquid Crystals, Gavin Hartnett
Spiral Patterns In Liquid Crystals, Gavin Hartnett
Honors Capstone Projects - All
Abstract not Included
Intracellular Signaling: How Do Cells Respond To Single And Multiple Inputs, Latoya Crayton
Intracellular Signaling: How Do Cells Respond To Single And Multiple Inputs, Latoya Crayton
Honors Capstone Projects - All
One important biological question is how the cell processes input information and decides what to respond. The cell can integrate the multiple inputs using linear and nonlinear dynamics to generate an appropriate output. This study focuses on the computerized recording of phototaxis (movement in relation to light direction) of Chlamydomonas cell populations response to green light, which activates the rhodopsin photoreceptor at their eyespots. The inputs are light stimulation of various wavelengths and intensities; and chemicals (IBMX, a PDE inhibitor; 2'5'-dideoxyadenosine, an adenylate cyclase inhibitor, 8-Br-cAMP-Na and Dibutyryl cAMP, cAMP analogs) affecting an important intracellular messenger, cAMP. The quantified output …
Photo-Induced Current Measurements In Chlamydomonas Cell Suspensions, Collin D. Capano
Photo-Induced Current Measurements In Chlamydomonas Cell Suspensions, Collin D. Capano
Honors Capstone Projects - All
In order to fully understand the principles behind phototaxis in flagellate algae, it is necessary to measure the electric currents these cells create when processing light stimuli. Many different techniques have been developed to do this. One of these techniques, measuring from cell suspensions, has a number of advantages over the others that makes it highly desirable. However, the lab that first developed this method of recording did not describe the setup very well. The result is that in the thirteen years since it was first reported, only one other independent lab has been able to reproduce the results despite …