Data Science Commons^™

Interactive Visualization Workflows For Mitigating Analytical Uncertainty, Kaustav Bhattacharjee

Dissertations

This dissertation takes a process-centric and stakeholder-first perspective for handling analytical uncertainty: the form of uncertainty that confronts data analysts' insight-generation processes in high-consequence decision-making scenarios. The cost of an incorrect decision when data is used for movie recommendations as opposed to when personal data is used to drive insights or when data-driven modeling is used to drive real-time decisions for maintaining the health of a grid are vastly different in terms of consequences. This dissertation looks at analytical uncertainty in two real-world scenarios: i) how sensitive information leakage can be prevented during the open data release process with data …

Visual Analytic Techniques For Interpretable Algorithmic Ranking Systems, Jun Yuan

Dissertations

Rankings have a profound impact on the increasingly data-driven society. From leisurely activities like the movies to watch, the restaurants to patronize; to highly consequential decisions, like making educational and occupational choices or getting hired by companies— these are all driven by sophisticated yet mostly opaque algorithmic rankers. A small change in how these rankers order the data items can have profound consequences, like deterioration of the prestige of a university or a job applicant missing out on being on the list of the top candidates for an organization. These scenarios necessitate data-driven and human-centered innovation to make rankers accessible, …

Advancing Prediction Of Stimulant Medication Misuse Through Graph Representation Learning, Hamid Razavi

Theses

The misuse of stimulant prescription medications poses a significant and escalating public health concern in the United States, particularly among young adults. Addressing this issue requires sophisticated methodologies capable of uncovering complex patterns and relationships in data. Geometric Deep Learning, a paradigm designed to analyze data with non-Euclidean structures, has achieved remarkable success across various domains, offering a powerful framework for tackling complex graph structure data challenges.

This study leverages Graph Convolutional Networks (GCNs) to predict the likelihood of stimulant medication misuse using data from the National Survey on Drug Use and Health (NSDUH). Individuals are represented as nodes in …

Cropsync: Ai-Powered Sustainable Crop Management, Ziad Doughan, Ibrahim Mneimneh, Zouheir Nakouzi, Noor Al Khaib, Samer Damaj, Jamal Chaaban, Hamza Mrad, Sari Itani

BAU Journal - Science and Technology

CropSync is a smart agriculture system that uses AI and IoT technologies to enable sustain- able crop management and precision farming. The system aims to address the challenges faced by the agriculture sector, such as increasing food production to meet global population demands while minimizing environmental impact. CropSync integrates sensors, cameras, and cloud-based analytics to provide farmers with real-time insights and recommendations for optimizing crop cul- tivation. The system upholds engineering professional and ethical standards, considering broader social, environmental, and economic implications. From a social perspective, CropSync improves food security and enhances farmers’ livelihoods through increased productivity and efficient re- …

An Ontology-Based Approach For Understanding Appendicectomy Processes And Associated Resources, Nadeesha Pathiraja Rathnayaka Hitige, Ting Song, Steven J Craig, Kimberley J Davis, Xubing Hao, Licong Cui, Ping Yu

Faculty, Staff and Student Publications

Background: Traditional methods for analysing surgical processes often fall short in capturing the intricate interconnectedness between clinical procedures, their execution sequences, and associated resources such as hospital infrastructure, staff, and protocols.

Aim: This study addresses this gap by developing an ontology for appendicectomy, a computational model that comprehensively represents appendicectomy processes and their resource dependencies to support informed decision making and optimise appendicectomy healthcare delivery.

Methods: The ontology was developed using the NeON methodology, drawing knowledge from existing ontologies, scholarly literature, and de-identified patient data from local hospitals.

Results: The resulting ontology comprises 108 classes, including 11 top-level classes and …

Physics-Informed Heterogeneous Spatiotemporal Graph Neural Network For Reservoir Simulation, Ahmed A.M.A. Abdullah

LSU Master's Theses

Reservoir simulation is the state-of-the-art method for predicting the flow of petroleum reservoir fluids in porous media. It provides an accurate and unbiased prediction of the performance of petroleum reservoirs under different operating conditions. Despite its advantages, reservoir simulation is computationally expensive; with typical full-field simulation models running for several hours. This limitation is worsened when simulating reservoirs with several equations for each cell, such as multiphysics or compositional reservoir simulation. The goal of this research is to provide a fast and accurate spatiotemporal machine-learning model that incorporates discretized governing mass balance equations for training. To achieve this, we propose …

Advancing Continuous Manufacturing: The Role Of Process Analytical Technology In Process Development, Samuel R. Henson

Electronic Theses and Dissertations

The pharmaceutical industry is actively pursuing technologies which improve manufacturing processes with the goal of producing high-quality pharmaceutical products for patients, manifesting in an industry-wide investment in continuous manufacturing (CM). Process analytical technology (PAT) has been recognized for its successful monitoring of critical quality attributes during routine production and is often cited alongside CM due to its ability to make timely, in-line measurements of intermediate materials. Various PAT tools are valuable in process development, particularly as continuous wet granulation processes are developed for use within pharmaceutical manufacturing. This work applied PAT and chemometric modeling during CM process development to enhance …

How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?, Yan Liu, Congjing Ran

Bulletin of Chinese Academy of Sciences (Chinese Version)

Data sovereignty has become deeply intertwined with various economic and social development factors such as technology, trade, economy, culture, society, and politics, leading to a “Pan-Data Sovereignty” competition pattern in the digital space. Through the digital stack model, which examines digital technologies in a layered framework, we can more clearly assess the competitive capacities in“Pan-Data Sovereignty” of China, United States, and European Union. The analysis identifies a three-tiered global “Pan-Data Sovereignty” competition structure among China, U.S., and EU, with each entity holding distinct advantages across various layers of the digital stack. Intense future competition is anticipated in fields such as …

Influence Of Antibody–Drug Conjugate Cleavability, Drug-To-Antibody Ratio, And Free Payload Concentration On Systemic Toxicities: A Systematic Review And Meta-Analysis, Shou Ching Tang, Carrie Wynn, Tran Le, Martin Mccandless, Yunxi Zhang, Ritesh Patel, Nita Maihle, William Hillegass

School of Medicine Faculty Publications

While in theory antibody drug conjugates (ADCs) deliver high-dose chemotherapy directly to target cells, numerous side effects are observed in clinical practice. We sought to determine the effect of linker design (cleavable versus non-cleavable), drug-to-antibody ratio (DAR), and free payload concentration on systemic toxicity. Two systematic reviews were performed via PubMed search of clinical trials published between January 1998—July 2022. Eligible studies: (1) clinical trial for cancer therapy in adults, (2) ≥ 1 study arm included a single-agent ADC, (3) ADC used was commercially available/FDA-approved. Data was extracted and pooled using generalized linear mixed effects logistic models. 40 clinical trials …

Safety And Optimality Monitors For Learning-Enabled Systems Using Conformal Prediction, Jackson Cox

McKelvey School of Engineering Graduate Student Theses & Dissertations

The use of machine learning to create data-driven plant models and controllers has led to an increased need for safety and optimality monitors for model-based systems. System plant models are subject to uncertainty due to learning constraints such as unseen data and overfitting or physical constraints such as unknown dynamics and noise. This uncertainty is detrimental to safety-critical systems and must be properly regulated. To curb this uncertainty, we create prediction sets using the guarantees provided by Conformal Prediction. With a user-specified high probability, these prediction sets contain the true plant system states for an entire prediction horizon, which we …

Where To Build Food Banks: A Machine Learning Approach, Gavin Ruan

The Journal of Purdue Undergraduate Research

Over 44 million Americans currently suffer from food insecurity, of whom 13 million are children. Food insecurity has been shown to cause a wide range of both physical and developmental issues. Across the United States, thousands of food banks and pantries serve as vital sources of food and other forms of aid for food-insecure families. By optimizing food bank locations, food banks and their resources would become more accessible to families who desperately require it. The aim of this paper is to build a machine learning framework that is able to optimize food bank locations and to consider factors such …

Predictive Maintenance Analysis Of Turbofan Engine Sensor Data, Stanley A. Melkumian

The Journal of Purdue Undergraduate Research

Predictive maintenance in aviation and aerospace applications is among the most explored problems in machine learning (ML) and artificial intelligence (AI), and datasets such as NASA’s C-MAPPS turbofan engine degradation simulation data have proven invaluable, helping researchers explore numerous questions on engine performance, maintenance, and failure. The purpose of this study was to extend the current research on predicting the remaining useful life (RUL) of engines and their risk classification. Starting with simple yet under-investigated nonlinear survival and random forest models, the analysis implemented eXtreme Gradient Boosting (XGBoost) and long short-term memory (LSTM) from TensorFlow’s Keras library. For both regression …

Calculation And Statistical Analysis Of Wins Above Replacement, Joshua Taylor

Departmental Honors & Graduate Capstone Projects

The Wins Above Replacement (WAR) statistic in Major League Baseball is a prominent metric used to estimate player value by quantifying all aspects of play in terms of wins added to a baseball team. We will use R to calculate WAR for all players from 1871 to 2012 and use data from those years to construct multivariate predictive models to attempt to estimate WAR for players from 2013 to 2024. We find strong correlations between predicted and actual WAR values for most models, with the exception of the polynomial predictive model for non-qualified pitchers.

And Climate Justice For All

DePaul Magazine

DePaul is taking its environmental sustainability and equity prowess to the next level through its Just DePaul and President's Sustainability Committee initiatives that incorporate a climate action plan and student voices. Plus, community partnership courses that involve students in environmental action and justice efforts.

Key Epigenetic And Signaling Factors In The Formation And Maintenance Of The Blood-Brain Barrier, Jayanarayanan Sadanandan, Sithara Thomas, Iny Elizabeth Mathew, Zhen Huang, Spiros L Blackburn, Nitin Tandon, Hrishikesh Lokhande, Pierre D Mccrea, Emery H Bresnick, Pramod K Dash, Devin W Mcbride, Arif Harmanci, Lalit K Ahirwar, Dania Jose, Ari C Dienel, Hussein A Zeineddine, Sungha Hong, Peeyush Kumar T

Faculty, Staff and Student Publications

The blood-brain barrier (BBB) controls the movement of molecules into and out of the central nervous system (CNS). Since a functional BBB forms by mouse embryonic day E15.5, we reasoned that gene cohorts expressed in CNS endothelial cells (EC) at E13.5 contribute to BBB formation. In contrast, adult gene signatures reflect BBB maintenance mechanisms. Supporting this hypothesis, transcriptomic analysis revealed distinct cohorts of EC genes involved in BBB formation and maintenance. Here, we demonstrate that epigenetic regulator's histone deacetylase 2 (HDAC2) and polycomb repressive complex 2 (PRC2) control EC gene expression for BBB development and prevent Wnt/β-catenin (Wnt) target genes …

Unlocking The Power Of Data: Enhancing Public Policy Through Advanced Data Infrastructure And Language Model Analysis, Zahid Asghar

CBER Conference

Data is the fundamental building block for advancements in artificial intelligence (AI), general AI (GAI), machine learning (ML), and large language models (LLMs). This study emphasizes the critical need for robust data infrastructure, arguing that without it, countries cannot fully benefit from technological advancements in various economic sectors. Governments possess vast repositories of both structured and unstructured data across multiple domains such as the judiciary, parliaments, and civil bureaucracy. However, these potential goldmines remain untapped due to inadequate data management capabilities and a lack of appreciation for the necessity of high-quality data. The research identifies key issues in public data …

Customer Data And The Digital Age, Mahdi Ansari

CBER Conference

Data is widely regarded as the most valuable resource in today’s economy, yet its value often eludes precise quantification. This paper examines customer data as an intangible capital asset and addresses the challenge of measuring its impact. A novel database was created by merging Compustat with online clickstream data capturing the activity of approximately 200 million users, providing proxies for data inflow based on visit metrics. The analysis documents that the distribution of firms’ customer data stocks follows a rightskewed log-normal pattern with a fat tail. Additionally, a positive relationship emerges between sales and data inflow, data stock, profit, and …

Statistical Analysis For Pre- And Post- Assessments Of Sdq And Idela Scores, Diego Murillo, Franceli L. Cibrian

Student Scholar Symposium Abstracts and Posters

This research aimed to assess the potential of Mazi Umntanakho ("Know Your Child") in tracking developmental milestones in young children. Mazi is a WhatsApp-based conversational agent that assists South African home visitors in evaluating and monitoring children's socio-emotional skills using the Strengths and Difficulties Questionnaire (SDQ) and the International Development and Early Learning Assessment (IDELA). A field study was conducted in low-income South African communities, where 95 home visitors assessed 1,208 children. This detailed analysis of the data was collected during that deployment, focusing on investigating whether assessment scores improved over time and whether the length of time between assessments …

Visualization Of Paleocurrents On A Web Application Using Gplates, Anjan Sapkota

MS in Computer Science Theses

Paleocurrents are flow directions derived from features of sedimentary rocks that reveal the direction of the current of wind or water that deposited the sediment. In 2015, Brand et al. created a global database of paleocurrents, which contains over 1,000,000 measurements worldwide: North America, South America, Australia, Great Britain, parts of Western Europe, China, Africa are fairly well represented; Antarctica, Eastern Europe, and Asia are modestly represented and Russia is poorly represented. The contribution of this thesis is a web application that uses the GPlates’ Application Programming Interface (API) to visualize global paleocurrents through time in an interactive way based …

Graph Neural Networks Powered Scientific Paper Recommendation, Junhao Shen

Computer Science and Engineering Theses and Dissertations

Scientific paper recommendation systems aim to help researchers discover relevant papers amidst the vast and ever-growing body of literature. With the exponential yearly increase in scientific publications, the demand for effective paper recommendation solutions has become both critical and increasingly challenging. In recent years, deep learning techniques have revolutionized recommender systems, and scientific paper recommendations have naturally integrated these advancements. In this dissertation, we address these challenges through three progressive contributions.

First, we enhance traditional content-based methods using Graph Neural Networks (GNNs) by introducing a Graph Convolutional Network-strengthened Topic Modeling (GCN-TM) approach. This method improves upon conventional topic modeling techniques …

Applications Of Neural Networks In Parkinson’S Disease Diagnosis, Saladin Minhaaj

Theses

Parkinson's disease (PD) is a complex and debilitating neurodegenerative disorder that affects millions of people worldwide. Early and accurate diagnosis is crucial for effective treatment and management of PD. This thesis explores the application of neural networks in PD diagnosis, leveraging their ability to learn patterns from large datasets and make accurate predictions.

Thesis provides an overview of PD, including its symptoms, diagnosis, and current challenges in diagnosis. We then delve into the fundamentals of neural networks, including supervised learning, mathematical interpretations, and parametric models. This research focuses on the development of neural network models that can accurately diagnose PD …

The Impact Of Student Engagement Activities On Future Climate Change Adaptation: The Case Of Student Simulation Models, Bassel Mostafa Elkalaf

Future Journal of Social Science

This paper explores the critical role of student engagement in addressing the growing challenges of climate change, with a focus on the Model United Nations (MUN) as a case study. As climate-related security threats increase globally, educational platforms that prepare youth for effective leadership in climate politics are more essential than ever. MUN, a widely practiced student activity simulating global policy-making, provides a valuable opportunity for students to deepen their understanding of the interconnectedness between climate change, peace, and security. By participating in MUN simulations, students engage in debates, develop innovative solutions, and practice diplomatic skills, all while exploring the …

A New Reduced Basis Method For Parabolic Equations Based On Single-Eigenvalue Acceleration, Qijia Zhai, Qingguo Hong, Xiaoping Xie

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we develop a new reduced basis (RB) method, named as Single Eigenvalue Acceleration Method (SEAM), for second order parabolic equations with homogeneous Dirichlet boundary conditions. The high-fidelity numerical method adopts the backward Euler scheme and conforming simplicial finite elements for the temporal and spatial discretizations, respectively. Under the assumption that the time step size is sufficiently small, and time steps are not very large, we show that the singular value distribution of the high-fidelity solution matrix U is close to that of a rank one matrix. We select the eigenfunction associated to the principal eigenvalue of the …

Explainable Ai In Medical Imaging: An Interdisciplinary Translational Approach, Caitlyn Chavez

Computational and Data Sciences (PhD) Dissertations

Advances in computer vision and image processing have made a clear impact on many fields, from healthcare diagnostics to autonomous driving. However, as these models become more complex, understanding their decision-making processes has grown increasingly challenging, making explainable AI (XAI) a crucial component of modern AI systems. The focus of this work is to integrate these new technologies alongside foundational methods of image processing to create tools that can be used by domain experts who are not programmers. Prior to delving into the projects which investigate these concepts, the methodologies, background, and the overall frameworks are discussed. In the first …

Tumor Expression Of Cd83 Reduces Glioma Progression And Is Associated With Reduced Immunosuppression, Malcolm F Mcdonald, Rachel Naomi Curry, Isabella O'Reilly, Brittney Lozzi, Alexis Cervantes, Zhung-Fu Lee, Anna Rosenbaum, Peihao He, Carrie Mohila, Arif O Harmanci, Akdes Serin Harmanci, Benjamin Deneen, Ganesh Rao

Faculty, Staff and Student Publications

Immunosuppression in malignant glioma remains a barrier to therapeutic development. CD83 overexpression in human and mouse glioma increases survival. CD83+ tumor cells promote signatures related to cytotoxic T cells, enhanced activation of CD8+ T cells, and increased proinflammatory cytokines. These findings suggest that tumor-expressed CD83 could mediate tumor-immune communications.

Optimization Of Markov Chain Modeling In Predicting College Student Retention, Kien Nguyen

Journal of Global Education and Research

College student retention is one of the most important metrics in higher education. With institutions across the US facing decreasing enrollment, developing a reliable retention prediction method is crucial. In recent years, the use of the Markov chain model in forecasting student enrollment and progression has become more common, but there is little work on its application in student retention. One key factor in determining this model's effectiveness is what parameters should be used in the student population’s segmentation or grouping. This study presents a rigorous algorithm, coupled with a prediction model, capable of selecting parameters that provide the most …

Basic Safety Message Generation Through A Video-Based Analytics For Potential Safety Application, Abyad Enan

All Theses

With the advancement of modern artificial intelligence techniques, computer vision can play a vital role in enhancing roadway safety by reducing the risk of imminent collisions. To do so, a vision-based safety application is required, where a roadside camera can monitor the roadway traffic and predict potential risks of crashes in real-time. If any risky situation or behavior is observed that may lead to a crash, then a safety application can send warnings to the vehicles at risk. For vision-based safety applications on a roadway section, it is important to accurately monitor each vehicle’s location, speed, acceleration, heading direction, etc. …

Debtor Eligibility Prediction Using Deep Learning With Chatbot-Based Testing, Reski Noviania, Enny Itje Sela, Luther Alexander Latumakulita, Steven R. Sentinuwo

Knowledge Engineering and Data Science

Predicting debtor eligibility is essential for effective risk management and minimizing lousy credit risks. However, financial institutions face challenges such as imbalanced data, inefficient feature selection, and limited user accessibility. This study combines Recursive Feature Elimination (RFE) and Deep Learning (DL) to improve prediction accuracy. It integrates a chatbot interface for user-friendly testing. RFE effectively identifies critical features, while the DL model achieves a validation accuracy of 97.62%, surpassing previous studies with less comprehensive methodologies. The chatbot's novel design not only ensures accessibility but also enhances user engagement through flexible input options, such as approximate values, enabling non experts to …

Optimal Strategy For Handling Unbalanced Medical Datasets: Performance Evaluation Of K-Nn Algorithm Using Sampling Techniques, Yulita Salim, Aulia Putri Utami, Abdul Rachman Manga, Huzain Azis, Fadhila Tangguh Admojo

Knowledge Engineering and Data Science

This study addresses the critical role of medical image classification in enhancing healthcare effectiveness and tackling the challenges of imbalanced medical datasets. It focuses on optimizing classification performance by integrating Canny edge detection for segmentation and Hu-moment feature extraction and applying oversampling and undersampling techniques. Five diverse medical datasets were utilized, covering Alzheimer’s and Parkinson’s diseases, COVID-19, brain tumours, and lung cancer. The K-Nearest Neighbors (K-NN) algorithm was implemented to enhance classification accuracy, aiming to develop a more robust framework for medical image analysis. The evaluation, conducted using cross-validation, demonstrated notable improvements in key metrics. Specifically, oversampling significantly enhanced lung …

A Hierarchical Density-Based Spatial Clustering Of Applications With Noise (Hdbscan) Approach For Identifying Potential Villages In Buleleng Regency, Dina Nur Amalina, Achmad Fauzan

Knowledge Engineering and Data Science

Buleleng Regency, located in Bali Province, possesses diverse village potential, including agricultural production and tourist attractions. However, this potential has not been fully optimized. Therefore, it is important to enhance village potential by clustering villages based on their specific characteristics to identify and prioritize those requiring special attention. This approach aims to promote equitable village development and reduce poverty levels. This study clusters villages in Buleleng Regency based on their potential using the Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN) method. The data utilized in this study comprises village potential data obtained from the Buleleng Regency Statistics Office …