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Articles 1 - 30 of 44
Full-Text Articles in Data Science
How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?, Yan Liu, Congjing Ran
How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?, Yan Liu, Congjing Ran
Bulletin of Chinese Academy of Sciences (Chinese Version)
Data sovereignty has become deeply intertwined with various economic and social development factors such as technology, trade, economy, culture, society, and politics, leading to a “Pan-Data Sovereignty” competition pattern in the digital space. Through the digital stack model, which examines digital technologies in a layered framework, we can more clearly assess the competitive capacities in“Pan-Data Sovereignty” of China, United States, and European Union. The analysis identifies a three-tiered global “Pan-Data Sovereignty” competition structure among China, U.S., and EU, with each entity holding distinct advantages across various layers of the digital stack. Intense future competition is anticipated in fields such as …
Benefits And Challenges Of Constructing Low-Altitude Air Route Network Infrastructure For Developing Low-Altitude Economy, Xiaohan Liao, Chenchen Xu, Huping Ye
Benefits And Challenges Of Constructing Low-Altitude Air Route Network Infrastructure For Developing Low-Altitude Economy, Xiaohan Liao, Chenchen Xu, Huping Ye
Bulletin of Chinese Academy of Sciences (Chinese Version)
Low-altitude airspace is a resource that needs to be fully explored, and the low-altitude economy is a new type of economic activity resulted from low-altitude airspace exploration and utilization. As the primary players of low-altitude flight activities, the commercialization and wide applications of unmanned aerial vehicles (UAVs) are promoting the prosperity of the low-altitude economy. A low-altitude air route network is an effective means to ensure the safe and efficient operations of a large number of UAVs, and it is also a new key infrastructure hosting low-altitude traffic. The history shows that the investment on public transport infrastructure as a …
Prospect And Problem Analysis Of Industry Data Application In Livestock And Poultry Breeding, Yiran Chen, Zhuqing Xiong, Jiaogen Zhou, Quan Wang, Jiancheng Shu, Yinfa Yan, Lanlin Yang, Zemeng Feng, Benhai Xiong, Yulong Yin
Prospect And Problem Analysis Of Industry Data Application In Livestock And Poultry Breeding, Yiran Chen, Zhuqing Xiong, Jiaogen Zhou, Quan Wang, Jiancheng Shu, Yinfa Yan, Lanlin Yang, Zemeng Feng, Benhai Xiong, Yulong Yin
Bulletin of Chinese Academy of Sciences (Chinese Version)
Livestock and poultry breeding is a pillar industry in China. The massive data in livestock and poultry breeding is a valuable resource. The market-oriented utilization of livestock and poultry breeding data plays an important role in improving industry standards, increasing industry profits, and driving the development of the entire industry chain. Currently, based on the demand for marketization of livestock and poultry breeding data, the application of new generation information technologies such as artificial intelligence and the Internet of Things in the process of livestock and poultry breeding to collect breeding process data, after de-sensitization and de-classification, through cloud computing, …
Promote Deep Integration Of Real Economy And Digital Economy, Qinmin Wang
Promote Deep Integration Of Real Economy And Digital Economy, Qinmin Wang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Deep integration of digital technology, industrial development, and data resources empowers development of the digital economy, constantly opens up new tracks, creates new momentum, and establishes new advantages, becoming a new powerful engine for global economic and social development. China attaches great importance to the high-quality development of the digital economy. This study discusses the practical experience of vigorously promoting digital industrialization and industrial digitization, promoting the deep integration of digital technology and the real economy, and accelerating the construction of a network power and digital China. It also proposes countermeasures and suggestions to further promote the efficient empowerment of …
Reflections On Strengthening Digital Public Goods Institutions To Promote Construction Of Open Source Innovation Ecosystem, Chao Zhang, Ze Feng, Kaihua Chen, Qigang Zhu
Reflections On Strengthening Digital Public Goods Institutions To Promote Construction Of Open Source Innovation Ecosystem, Chao Zhang, Ze Feng, Kaihua Chen, Qigang Zhu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The digital public goods institutions are important foundations for promoting the development of an open source innovation ecosystem, which helps to break the key limitations faced by China’s open source innovation ecosystem, such as the lack of unity in technology routes and concentration of R&D power. Based on discussing the significance of improving digital public goods institutions, this study reviews the experience of major countries in the world in building digital public goods institutions and analyzes the prominent problems faced by the construction of China’s digital public goods institutions. This study points out that China’s open source innovation ecosystem faces …
Status Quo Of Large-Scale Models, Risks And Challenges, And Recommended Countermeasures, Le Cheng, Yang Xiao
Status Quo Of Large-Scale Models, Risks And Challenges, And Recommended Countermeasures, Le Cheng, Yang Xiao
Bulletin of Chinese Academy of Sciences (Chinese Version)
Large-scale models (large models) are not only central to technological innovation, but also deeply entwined with national security, economic transformation, and social governance. This study examines the status quo of large-model development, identifies the key risks and challenges, and proposes response strategies, aiming to provide theoretical and policy insights for China’s navigations in global artificial intelligence (AI) competition and advances technological innovation. The research indicates that competition in the large-model market is fierce, while the industry is gradually consolidating. Competition in large models between China and the United States has escalated into a form of geopolitical contest. From a technical …
Construction Of Data Factor Circulation Law System In The United States And Its Reflection For China, Zihan Lin, Youmei Ma, Feng Guo
Construction Of Data Factor Circulation Law System In The United States And Its Reflection For China, Zihan Lin, Youmei Ma, Feng Guo
Bulletin of Chinese Academy of Sciences (Chinese Version)
As a pioneer country in the global digital economy, the United States has established a relatively complete system for the circulation of data elements. The focus is on government data openness, with the United States forming a legislative system for data openness at both federal and state levels to ensure data freedom and openness. In the field of personal data trading, the United States has established a relatively relaxed legal environment and data brokers to promote data circulation and trading. At present, China is actively promoting the market-oriented allocation reform of data elements, building a multi-level data element market, and …
Key Technology Selection And Countermeasures To Promote Full Lifecycle Data Governance, Yuyao Feng, Hongyun Zhang, Pengfei Wang, Jianping Li, Zongben Xu
Key Technology Selection And Countermeasures To Promote Full Lifecycle Data Governance, Yuyao Feng, Hongyun Zhang, Pengfei Wang, Jianping Li, Zongben Xu
Bulletin of Chinese Academy of Sciences (Chinese Version)
In recent years, the digital economy, driven by data as a critical element, has developed rapidly. Nevertheless, China’s progress in data factorization and valorization is still at a preliminary stage. The data governance system remains underdeveloped, with numerous challenges and technical issues arising in the full lifecycle governance of data, including supply, circulation, application, and security protection. Against this backdrop, this study analyzes the primary technical bottlenecks encountered during the modernization of China’s data governance framework. By employing bibliometric analysis, patent data analysis, Delphi surveys, and expert opinions, a critical technology list to support the modernization of data governance in …
Innovation Path At Institute For Protein Design Of Washington University And Its Enlightenment For Construction Of New Life Sciences R&D Institutions, Runzhou Zhao, Ming Ni, Yunzhi Fa, Xiaochen Bo, Jian Jiao
Innovation Path At Institute For Protein Design Of Washington University And Its Enlightenment For Construction Of New Life Sciences R&D Institutions, Runzhou Zhao, Ming Ni, Yunzhi Fa, Xiaochen Bo, Jian Jiao
Bulletin of Chinese Academy of Sciences (Chinese Version)
The Institute for Protein Design (IPD) at the University of Washington is a pioneering local and state-supported non-profit scientific research institution. Since its establishment in 2012, IPD has seized the opportunity of AI for Science and open science, and continuously enhanced its capabilities of fundamental innovations, breakthrough technologies, and industrial impact. We summarized five factors contributing to IPD’s development, including focusing on the cutting-edge issues of basic scientific research to gain a first-mover advantage and then further expand, integrating AI-enhanced digital tools and solid experimental validations, facilitating the integrated development of innovation and industrial chains, giving full play to the …
Big Life-Science: Study Of Omics From Microscopic To Mesoscopic Scales, Jiarui Wu
Big Life-Science: Study Of Omics From Microscopic To Mesoscopic Scales, Jiarui Wu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The human genome project at the turn of the century opened a new era of life science research and formed various omics characterized by holistic high-throughput research. The initial omics research was mainly carried out at the molecular level, such as genomics, transcriptomics, proteomics, etc., showing a new paradigm of data-driven research. With the development of research technologies, the omics research has risen to the mesoscopic level, the representative is the “Human Cell Atlas” project launched in 2017. At present, researchers have been able to carry out omics research at the level of tissues, organs, and even individuals, and resulted …
Brain Science And Brain-Inspired Intelligence In Intelligent Era, Xu Zhang
Brain Science And Brain-Inspired Intelligence In Intelligent Era, Xu Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
With intelligence technology as the core technology and intelligent computing power as the productive force, the intelligent era has once again pushed brain science to the forefront of world science and technology. Brain science is the science that studies the nature and rule of cognition and intelligence of human, animal, and machine. A comprehensive analysis of the structure and functional connection rule of the nervous system will eventually draw the functional connectivity map of the brain. In the past decade, neuroscience research has been committed to systematically analyzing the types of neurons and neural structural connections of the nervous system, …
Advances In Data-Driven Life Sciences Research, Haiping Jiang, Chunchun Gao, Wenhao Liu, Yungui Yang, Xin Li
Advances In Data-Driven Life Sciences Research, Haiping Jiang, Chunchun Gao, Wenhao Liu, Yungui Yang, Xin Li
Bulletin of Chinese Academy of Sciences (Chinese Version)
The field of life sciences is rapidly evolving, driven by advancements in experimental techniques and vast biological big data which gradually arise and play an increasingly important role in life science research. First of all, biological big data has diversity and complexity, including genomic data, epigenomic data, proteomic data and other types. These data provide researchers with more comprehensive information and help reveal the laws behind life phenomena. Second, new data-driven developments and applications in life sciences cover many fields such as gene editing, precision medicine, drug development, etc., providing unprecedented possibilities for human health and quality of life. However, …
Technology Innovation Is The Key To Future Space Science Missions, Ji Wu
Technology Innovation Is The Key To Future Space Science Missions, Ji Wu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Space science is one of the important space activities of China together with space technology and space application. Although it is a space program aimed at scientific discovery and breakthrough, with the development of technology and the increasing number of achievements received in the past, space science missions require more and more technological innovation to achieve their goals. This study first reviews the development trend of space science missions since their birth, then analyzes the cultivation process of space science mission proposals with technological innovation and the responsibilities of the chief scientist leading such tasks, and finally analyzes and proposes …
Promoting Ecosystem Based Marine Management Through A Marine Ecological Classification And Zoning System, Wenhai Lu, Xiao Li, Meng Cui
Promoting Ecosystem Based Marine Management Through A Marine Ecological Classification And Zoning System, Wenhai Lu, Xiao Li, Meng Cui
Bulletin of Chinese Academy of Sciences (Chinese Version)
Ecosystem based ocean management is an important means of building marine ecological civilization. The current marine ecological classification and zoning in China comprehensively sorts out the types and natural geographical characteristics of marine ecosystems, divided the Chinese seas and adjacent waters into several levels of ecological spatial units according to different scales, effectively characterizes the geographical distribution features of marine biological communities and their habitats, and provides effective support for ecosystem based marine management. This study analyzed the practical significance of marine ecological classification and zoning. Based on a review of the development of marine ecological classification and zoning, this …
Research On Boundary Reconstruction And Government Supervision Strategy For Digital Platform, Jichang Dong, Feiyang Zhan, Wei Li, Jinlu Guo, Ying Liu
Research On Boundary Reconstruction And Government Supervision Strategy For Digital Platform, Jichang Dong, Feiyang Zhan, Wei Li, Jinlu Guo, Ying Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Digital platform is the most important form of organization in the digital era. How to clarify the boundary between platform autonomy and government regulation so as to exert the order maintenance function of platforms effectively is the key issue in the region of the digital economy governance. This study firstly introduces the basic model of platform autonomy and the regulatory challenges it faces, basing on the background of the emergence of digital platform autonomy. Secondly, through a comparative analysis of the regulatory theories and legal policies of the digital platform autonomy in the European Union and the United States, this …
Research On Chinese Data Sovereignty Policy Based On Lda Model And Policy Instruments, Han Qiao, Junru Xu
Research On Chinese Data Sovereignty Policy Based On Lda Model And Policy Instruments, Han Qiao, Junru Xu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Data sovereignty has become an important component of national sovereignty in the dual context of the digital economy development and the overall national security concept. Major countries and regions are actively carrying out data sovereignty strategic deployment and engaging in fierce competition in data resources, data technology, and data rules. This work adopts the policy text analysis method to study China’s data sovereignty policy, and employs the LDA model and policy instruments to quantitatively analyze the process evolution and thematic characteristics of China’s data sovereignty policy. Drawing on these findings, this study comprehensively considers the global data sovereignty policy and …
Hillside Agricultural Machinery And Agricultural Intelligence Driven By New Technologies, Hong Qiao, Yanfeng Lyu, Enhao Zheng
Hillside Agricultural Machinery And Agricultural Intelligence Driven By New Technologies, Hong Qiao, Yanfeng Lyu, Enhao Zheng
Bulletin of Chinese Academy of Sciences (Chinese Version)
Hilly and mountainous areas play a crucial role in China’s agricultural production. However, the low level of comprehensive mechanization for crop cultivation, planting, and harvesting in these regions severely hampers the modernization of agriculture. The complex terrain and diverse cropping patterns in hilly areas necessitate the development of specialized agricultural machinery and robots tailored to these unique landscapes. To advance this process, the Chinese government has introduced a series of policies in recent years to support the research and development of agricultural machinery for hilly regions, providing strong backing for the advancement of agricultural technology in these areas. Against this …
The Fuxi Farm: Practice Exploration And Reflection On Integrated Innovation Of Smart Agriculture Technology, Yucheng Zhang, Xiaobo Zhang, Shuqin Gao, Congcong Zheng, Jingyao Zhang, Ya Wen, Lujun Li, Zhuo Wang, Tie Li, Honglong Zhao
The Fuxi Farm: Practice Exploration And Reflection On Integrated Innovation Of Smart Agriculture Technology, Yucheng Zhang, Xiaobo Zhang, Shuqin Gao, Congcong Zheng, Jingyao Zhang, Ya Wen, Lujun Li, Zhuo Wang, Tie Li, Honglong Zhao
Bulletin of Chinese Academy of Sciences (Chinese Version)
Smart agriculture plays a pivotal role in enhancing food security by optimizing resource use and improving crop yields through the application of AI technologies. The establishment of smart farms is critical to rapidly integrating AI into agricultural production, offering platforms for both the deployment and testing of AI solutions and equipment. This paper examines the development of smart farms, with a focus on practices from developed countries, and assesses the current status of smart farming in China. We then focus on exploring the content, pathways, and practices for constructing a smart agricultural production system in China through the establishment of …
Accelerate Innovation Of Forage Intelligent Breeding Technology: Reflection And Suggestions, Haichun Jing, Weijuan Hu, Jingbo Jin, Jingyu Zhang, Yao Zhou, Yue Gong, Gang Yao, Lei Wang, Kang Chong
Accelerate Innovation Of Forage Intelligent Breeding Technology: Reflection And Suggestions, Haichun Jing, Weijuan Hu, Jingbo Jin, Jingyu Zhang, Yao Zhou, Yue Gong, Gang Yao, Lei Wang, Kang Chong
Bulletin of Chinese Academy of Sciences (Chinese Version)
The world is facing unprecedented changes today, with continuous population growth intensifying the pressure on food demand. The shift towards diversified dietary structures has increased the demand for feed grains, while climate change further threatens China’s food security by affecting agricultural productivity and carbon sequestration economy. At present, China has entered a new era of food supply and feed. As the food supply for animals, forage is the core component of feed, and its industrial development has profound strategic significance for ensuring national food security. This study analyzes the current situation of China’s forage seed industry, summarizes the cutting-edge achievements …
Rapid Soil Detection Technology Aids In Assessing Soil Nutrients In China, Wei Wu, Xiaoyong Liao, Xiaopeng Li, Yuntao Wu, Huixian Lu, Yucheng Zhang, Jiabao Zhang
Rapid Soil Detection Technology Aids In Assessing Soil Nutrients In China, Wei Wu, Xiaoyong Liao, Xiaopeng Li, Yuntao Wu, Huixian Lu, Yucheng Zhang, Jiabao Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Soil quality is the core issue for ensuring China’s food security, and soil health is the top priority of soil quality. Comprehensive, rapid and accurate acquisition of soil background data is the prerequisite for achieving homogeneous soil management and formulating balanced fertilization strategies, which will play a key role in improving non-point source pollution caused by unreasonable fertilization and achieving balanced grain yield increase. This study reviews rapid soil testing methods both domestically and internationally. Based on previous research, it proposes a technical approach to rapidly detect soil nutrient concentrations by calculating the gamma quanta released during the decay of …
Artificial Intelligence Innovation For Smart Plant Factory To Diversify Its Big Food Production Functions, Huaqin Gong, Haichun Jing, Xin Tan, Xianhui Wang, Yucheng Zhang, Rongcheng Lin, Mingyu Yang, Shuang Lin, Hualing Xie, Yanping Yang, Shitang Ye, Peng Li, Tingyun Kuang
Artificial Intelligence Innovation For Smart Plant Factory To Diversify Its Big Food Production Functions, Huaqin Gong, Haichun Jing, Xin Tan, Xianhui Wang, Yucheng Zhang, Rongcheng Lin, Mingyu Yang, Shuang Lin, Hualing Xie, Yanping Yang, Shitang Ye, Peng Li, Tingyun Kuang
Bulletin of Chinese Academy of Sciences (Chinese Version)
China’s food security is facing more and more severe and complex challenges, such as tight balance between food demand and supply, the upgrading of consumption structure, and resource constraints. The plant factory is an advanced scenario in agricultural production, a diversified food production system that gets rid of the constraints of “ask for food from the mother nature” and respond to disasters and wars, and is oriented to space. Nevertheless, the high cost greatly limits the application and development of plant factories. The rapid development of artificial intelligence will bring new opportunities for the innovative development and expansion of plant …
Data And Intelligent Driven Space Science Experimental Research: New Exploration Under Ai4s Paradigm, Shengyang Li, Kang Liu, Yunfei Liu, Chufan Lai
Data And Intelligent Driven Space Science Experimental Research: New Exploration Under Ai4s Paradigm, Shengyang Li, Kang Liu, Yunfei Liu, Chufan Lai
Bulletin of Chinese Academy of Sciences (Chinese Version)
As artificial intelligence (AI) technology continues to advance, it is revolutionizing various scientific fields, giving rise to a new research paradigm known as AI for Science (AI4S). This study highlights the unique multidisciplinary advantages of AI in space science experiments conducted under microgravity conditions. It provides a comprehensive analysis of AI-driven approaches to multimodal space science experiment data pattern mining, domain knowledge extraction, interdisciplinary knowledge integration, and cognitive intelligence. The study reveals AI’s substantial potential to enhance intelligent scientific research, cognition, and discovery within the realm of space science experiments. The findings suggest that data-driven space science research, as a …
Current Status And Applications Of Microbial Chassis Strains For Chinese Biomanufacturing Industry, Guoqiang Chen, Fuqing Wu, Shuang Zheng, Jun Ding, Junting Sheng
Current Status And Applications Of Microbial Chassis Strains For Chinese Biomanufacturing Industry, Guoqiang Chen, Fuqing Wu, Shuang Zheng, Jun Ding, Junting Sheng
Bulletin of Chinese Academy of Sciences (Chinese Version)
Biomanufacturing is an important component of new quality productive forces, representing the commanding height of the new round of technological revolution and serving as a new engine for industrial transformation following information technology. It demonstrates vast application prospects in fields such as renewable energy, advanced materials, biomedicine, green food, and environmental protection. Biomanufacturing utilizes chassis microorganisms similar as “microchip” to produce various bioproducts via processes including chassis design and construction, large-scale cell cultivation, and product purifications. Most chassis microorganisms in biomanufacturing were not domestically identified. This study summarizes the types of common chassis microorganisms both domestically and internationally, as well …
Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang
Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Engineering cells are a core component of green bio-manufacturing. The efficient testing and acquisition of engineering cells with the desired phenotype is a critical factor in the successful implementation of bio-manufacturing. In recent years, based on microfluidics technologies, non-culture type single-cell phenotype high-throughput test equipment and culture type phenotype high-throughput test equipment for the growth and metabolism of single cell in a bioreactor have been developed such as microdroplet and microchamber, realizing high-throughput, automated, miniaturized, and integrated testing of the phenotypes of engineering cells and providing a powerful tool for the breeding of engineering cells. This review systematically compiles the …
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Biomanufacturing, an emerging production method, is becoming a significant trend in global economic development and has garnered widespread international attention. Platform facilities are vital to the biomanufacturing industry’s development, serving as both the foundation for technological innovation and the bridge between research outcomes and practical applications. This study analyzes three key types of platform facilities and their operational mechanisms: technology innovation platforms (exemplified by the U.S. Agile BioFoundry), pilot-scale platforms (represented by European Bio Base Europe Pilot Plant), and industry incubation platforms (illustrated by the UK SynbiCITE). Drawing from these successful examples and examining China’s current platform infrastructure, this paper …
Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang
Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Synthetic biology is hailed as the third revolution in life sciences after the discovery of the DNA double helix structure and genomic technology, and is the core driving force for the leapfrog development of next-generation biomanufacturing and the future bioeconomy, opening up an opportunity window for the reshaping of the global manufacturing map. How to strategically position the synthesis biology industry and seize the strategic high ground in the industry is a core topic of interest for global science and technology powers and manufacturing powers. Based on the identification of problems in the development of China’s synthesis biology industry, this …
Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu
Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Clarifying the internal logic of big data to support modern agricultural production is helpful to cultivate and develop new quality productive forces in agriculture. From the perspective of economics, this study proposes that the role of big data in modern agricultural production is mainly reflected in two levels. Firstly, it improves the total factor productivity of the traditional agricultural production function. Secondly, it changes the factor endowment structure of agricultural production and forms a new agricultural production function. Based on these, the realization form of big data to support modern agricultural production can be summarized as improving the efficiency of …
Recent Progress And Perspectives On Development Of Gene Editing Tools, Zixian Liu, Chengping Li, Gogo Jun-Jie Liu
Recent Progress And Perspectives On Development Of Gene Editing Tools, Zixian Liu, Chengping Li, Gogo Jun-Jie Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The gene editing field has witnessed remarkable advancements in recent years, leading to the establishment and refinement of multidimensional gene editing platforms. These innovations have enabled precise targeted gene knockout, repair, and insertion. These tools have stimulated significant progress in fundamental research, therapeutics, agriculture, environment protection, and industrial applications. In this review, we provide a comprehensive overview of the milestones in gene editing tool development and offer perspectives on potential future directions for this rapidly evolving field.
Microbial Production Of Feed Amino Acids Promotes Reduction And Replacement Of Soybean Meal, Jia Liu, Qi Sheng, Kaifang Liu, Liming Liu
Microbial Production Of Feed Amino Acids Promotes Reduction And Replacement Of Soybean Meal, Jia Liu, Qi Sheng, Kaifang Liu, Liming Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
With the promotion of soybean meal reduction and substitution as well as lower-protein diet technologies, China has become a leading global producer of feed amino acids. However, the amino acid industry faces significant challenges due to its relatively late start in independently developing industrial strains, resulting in relatively lagging key economic and technical parameters and a less robust intellectual property framework. The rapid progress of synthetic biology has provided promising avenues for the design and optimization of industrial amino acid-producing strains, offering new opportunities for the amino acid fermentation industry to enhance the global competitiveness. This study offers an in-depth …
Current Status And Prospect Of Industrial Filamentous Fungi In Biomanufacturing, Zhiqiang Du, Ping Men, Yu Zhou, Xuan Zhang, Xuenian Huang, Xuefeng Lyu
Current Status And Prospect Of Industrial Filamentous Fungi In Biomanufacturing, Zhiqiang Du, Ping Men, Yu Zhou, Xuan Zhang, Xuenian Huang, Xuefeng Lyu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Filamentous fungi, a critical class of industrial microorganisms pivotal to the biomanufacturing industry, has extensive applications in various fields such as pharmaceuticals, food, agriculture, and chemical materials, which are playing a vital role in human life. Recently, innovations in synthetic biology have further driven the application of industrial filamentous fungi in biomanufacturing, highlighting their critical role in this field. This article presents a comprehensive review of the recent progress in the field, covering the latest developments in genetic modification techniques for industrial filamentous fungi, successful cases of rational strain improvement strategies aimed to enhance the quality and efficiency of current …