Databases and Information Systems Commons^™

An Event-Driven Approach To Computerizing Clinical Guidelines Using Xml, Bing Wu, Essam Mansour, Kudakwashe Dube, Jianxin Li

Conference Papers

Clinical events form the basis of patient care practice. Their computerization is an important aid to the work of clinicians. Clinical guidelines or protocols direct clinicians and patients on when and how to handle clinical problems. Thus, clinical guidelines are an encapsulation of clinical events. Hence, an event-driven approach to computerizing the management of clinical guidelines is worthy of investigation. In our framework, called SpEM, the main clinical guideline management dimensions are specification, execution, and manipulation. This paper presents an event-driven approach, within the context of the SpEM framework, to manage clinical guidelines. The event-driven approach is based on the …

Batch Mode Active Learning And Its Applications To Medical Image Classification, Steven C. H. Hoi, Rong Jin, Jianke Zhu, Michael R. Lyu

Research Collection School Of Computing and Information Systems

The goal of active learning is to select the most informative examples for manual labeling. Most of the previous studies in active learning have focused on selecting a single unlabeled example in each iteration. This could be inefficient since the classification model has to be retrained for every labeled example. In this paper, we present a framework for "batch mode active learning" that applies the Fisher information matrix to select a number of informative examples simultaneously. The key computational challenge is how to efficiently identify the subset of unlabeled examples that can result in the largest reduction in the Fisher …

A Database And Tool, Im Browser, For Exploring And Integrating Emerging Gene And Protein Interaction Data For Drosophila, Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jodi R. Parrish, Farshad Fotouhi, Russell L. Finley Jr

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of interaction data derived from both experimental and computational techniques for a number of organisms. The volume of this data combined with the variety of specific forms it can take has created a need for comprehensive databases that include all of the available data sets, and for exploration tools to facilitate data integration and analysis. One powerful paradigm for the navigation and analysis of interaction data is an interaction graph or map that represents proteins …

K-Spmm: A Database Of Murine Spermatogenic Promoters Modules & Motifs, Yi Lu, Adrian E. Platts, G Charles Ostermeier, Stephen A. Krawetz

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Understanding the regulatory processes that coordinate the cascade of gene expression leading to male gamete development has proven challenging. Research has been hindered in part by an incomplete picture of the regulatory elements that are both characteristic of and distinctive to the broad population of spermatogenically expressed genes.

Description

K-SPMM, a database of murine Spermatogenic Promoters Modules and Motifs, has been developed as a web-based resource for the comparative analysis of promoter regions and their constituent elements in developing male germ cells. The system contains data on 7,551 genes and 11,715 putative promoter regions …

Information Systems And Health Care Xiii: Examining The Critical Requirements, Design Approaches And Evaluation Methods For A Public Health Emergency Response System, Ann L. Fruhling

Information Systems and Quantitative Analysis Faculty Publications

Research pertaining to emergency response systems has accelerated over the past few years, particularly since 9/11 events, and more recently due to Hurricane Katrina and concern over a potential of an avian flu pandemic. This study examines the requirements that are the most demanding with respect to software and hardware, and the associated design strategies for a public health emergency response system (ERS) for electronic laboratory diagnostics consultation. In addition, this study illustrates ways to evaluate the design decisions.

An important goal of a public health ERS is to improve the communication and notification of life-threatening diseases and harmful agents. …

Dynamic Generation Of A Table Of Contents With Consumer-Friendly Labels, Trudi Miller '08, Gondy Leroy, Elizabeth Wood

CGU Faculty Publications and Research

Consumers increasingly look to the Internet for health information, but available resources are too difficult for the majority to understand. Interactive tables of contents (TOC) can help consumers access health information by providing an easy to understand structure. Using natural language processing and the Unified Medical Language System (UMLS), we have automatically generated TOCs for consumer health information. The TOC are categorized according to consumer-friendly labels for the UMLS semantic types and semantic groups. Categorizing phrases by semantic types is significantly more correct and relevant. Greater correctness and relevance was achieved with documents that are difficult to read than with …

Health Information Text Characteristics, Gondy Leroy, Evren Eryilmaz '11, Benjamin T. Laroya

CGU Faculty Publications and Research

Millions of people search online for medical text, but these texts are often too complicated to understand. Readability evaluations are mostly based on surface metrics such as character or words counts and sentence syntax, but content is ignored. We compared four types of documents, easy and difficult WebMD documents, patient blogs, and patient educational material, for surface and content-based metrics. The documents differed significantly in reading grade levels and vocabulary used. WebMD pages with high readability also used terminology that was more consumer-friendly. Moreover, difficult documents are harder to understand due to their grammar and word choice and because they …

Using A Digital Library Of Images For Communication: Comparison Of A Card-Based System To Pda Software, Trudi Miller '08, Gondy Leroy, John Huang '05, Serena Chuang '05

CGU Faculty Publications and Research

Autism spectrum disorder has become one of the most prevalent developmental disorders and one of the main impairments is difficulty with communication. One method of augmentative and alternative communication is the use of the Picture Exchange Communication System (PECS) to create messages using a series of images printed on cards and organized in binders. We are developing a digital alternative based on an image library that is displayed on a personal digital assistant (PDA). We conducted an initial user acceptance study that compared the effectiveness and usability of both systems. The study showed that the PDA system was able to …