Databases and Information Systems Commons^™

A Database And Tool, Im Browser, For Exploring And Integrating Emerging Gene And Protein Interaction Data For Drosophila, Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jodi R. Parrish, Farshad Fotouhi, Russell L. Finley Jr

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of interaction data derived from both experimental and computational techniques for a number of organisms. The volume of this data combined with the variety of specific forms it can take has created a need for comprehensive databases that include all of the available data sets, and for exploration tools to facilitate data integration and analysis. One powerful paradigm for the navigation and analysis of interaction data is an interaction graph or map that represents proteins …

K-Spmm: A Database Of Murine Spermatogenic Promoters Modules & Motifs, Yi Lu, Adrian E. Platts, G Charles Ostermeier, Stephen A. Krawetz

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Understanding the regulatory processes that coordinate the cascade of gene expression leading to male gamete development has proven challenging. Research has been hindered in part by an incomplete picture of the regulatory elements that are both characteristic of and distinctive to the broad population of spermatogenically expressed genes.

Description

K-SPMM, a database of murine Spermatogenic Promoters Modules and Motifs, has been developed as a web-based resource for the comparative analysis of promoter regions and their constituent elements in developing male germ cells. The system contains data on 7,551 genes and 11,715 putative promoter regions …

Information Systems And Health Care Xiii: Examining The Critical Requirements, Design Approaches And Evaluation Methods For A Public Health Emergency Response System, Ann L. Fruhling

Information Systems and Quantitative Analysis Faculty Publications

Research pertaining to emergency response systems has accelerated over the past few years, particularly since 9/11 events, and more recently due to Hurricane Katrina and concern over a potential of an avian flu pandemic. This study examines the requirements that are the most demanding with respect to software and hardware, and the associated design strategies for a public health emergency response system (ERS) for electronic laboratory diagnostics consultation. In addition, this study illustrates ways to evaluate the design decisions.

An important goal of a public health ERS is to improve the communication and notification of life-threatening diseases and harmful agents. …