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Full-Text Articles in Databases and Information Systems

Fusing Heterogeneous Data For Alzheimer's Disease Classification, P. S. Pillai, Tze-Yun Leong Aug 2015

Fusing Heterogeneous Data For Alzheimer's Disease Classification, P. S. Pillai, Tze-Yun Leong

Research Collection School Of Computing and Information Systems

In multi-view learning, multimodal representations of a real world object or situation are integrated to learn its overall picture. Feature sets from distinct data sources carry different, yet complementary, information which, if analysed together, usually yield better insights and more accurate results. Neuro-degenerative disorders such as dementia are characterized by changes in multiple biomarkers. This work combines the features from neuroimaging and cerebrospinal fluid studies to distinguish Alzheimer's disease patients from healthy subjects. We apply statistical data fusion techniques on 101 subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. We examine whether fusion of biomarkers helps to improve diagnostic …


Bridging The Vocabulary Gap Between Health Seekers And Healthcare Knowledge, Liqiang Nie, Yiliang Zhao, Akbari Mohammad, Jialie Shen, Tat-Seng Chua Feb 2015

Bridging The Vocabulary Gap Between Health Seekers And Healthcare Knowledge, Liqiang Nie, Yiliang Zhao, Akbari Mohammad, Jialie Shen, Tat-Seng Chua

Research Collection School Of Computing and Information Systems

The vocabulary gap between health seekers and providers has hindered the cross-system operability and the interuser reusability. To bridge this gap, this paper presents a novel scheme to code the medical records by jointly utilizing local mining and global learning approaches, which are tightly linked and mutually reinforced. Local mining attempts to code the individual medical record by independently extracting the medical concepts from the medical record itself and then mapping them to authenticated terminologies. A corpus-aware terminology vocabulary is naturally constructed as a byproduct, which is used as the terminology space for global learning. Local mining approach, however, may …