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Full-Text Articles in Other Chemistry
Approaches Toward Novel 1,2,3-Triazole Sensors For The Detection Of Anions And Heavy Metal Cations, Richard D. Govan
Approaches Toward Novel 1,2,3-Triazole Sensors For The Detection Of Anions And Heavy Metal Cations, Richard D. Govan
Electronic Theses and Dissertations
Cations and anions play pivotal roles in biological and physiological processes, however an imbalance in concentration of any ion can be detrimental. Therefore, research into the selective recognition of anions and heavy metal cations has acquired much attention. One approach involves the use of chemosensors. Upon interaction with targeted analytes, chemosensors produce a distinct response, in some cases a fluorescent or colorimetric signal. The 1,2,3-triazole unit has much potential as a chemical sensor due to its unique photophysical properties. The specificity, selectivity, and signaling mechanism of triazole sensors can be tuned with conjugation in the motif and choice and placement …
Preventing Gene Expression Through The Interruption Of Dna Binding, Olivia Perdue
Preventing Gene Expression Through The Interruption Of Dna Binding, Olivia Perdue
Honors College Theses
The interruption of DNA binding is a gateway to the inhibition of unregulated expression of genes which can possibly lead to illnesses such as cancer and epilepsy. The goal of this research is to produce high affinity DNA binding molecules which could act to displace the binding of natural transcription factor thus reducing the over- or under-expression of various proteins. Literature shows that the interruption of DNA binding can be completed using both organic and inorganic means, such as by means of natural transcription factors like the NF-κB protein or with metal-ligand complexes in order to bind DNA. NF-κB, a …
Assessment Of Short-Term Toxicity Of Titanium Dioxide Nano Fiber (Tdnf) In Sprague Dawley Rats, Daniel A. Hunter
Assessment Of Short-Term Toxicity Of Titanium Dioxide Nano Fiber (Tdnf) In Sprague Dawley Rats, Daniel A. Hunter
Electronic Theses and Dissertations
Nanotechnology is easily becoming one of the fastest growing markets around the globe. Synthetic nanomaterials have many unique chemical and physical properties, mainly due to their huge specific surface area and chemical makeup. Specifically, titanium dioxide (TiO2) nanomaterials have high stability, anticorrosive and photocatalytic properties. These nanomaterials have applications for semiconductor photocatalysis, treatment of water, as a photoactive material in nanocrystalline solar cells, and medicine. However, not much is known about the toxicity of TiO2 in the nanofiber form. The objective of the present study is to investigate the adverse effects associated with acute ingestion of TiO …