Other Chemistry Commons^™

Palladium-Catalyzed Carbonyl Allylation Reactions Using Tin Chloride: A Mini-Review, Armando M. Guidote Jr, Mikael John A. Baltazar, Roy Kristian C. Yanela, Noriyuki Suzuki

Chemistry Faculty Publications

The treatment of allylic alcohols as synthons of carbanions for carbonyl allylation reactions in the presence of a Pd-SnCl2 system has been one of the most interesting and most useful developments demonstrated by Yoshiro Masuyama and co-workers in the field of organic synthesis. The reaction makes use of palladium as an effective catalyst and tin (II) chloride as a low-valent reducing agent which also effectively transforms the allylic group to a nucleophilic group. The organic, as well as organometallic, chemistry of how the transformations occur and how the metals take part in the reaction is of great interest. These could …