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Full-Text Articles in Other Chemistry
Seminaphthofluorones Are A Family Of Water-Soluble, Low Molecular Weight, Nir-Emitting Fluorophores, Youjun Yang, Mark Lowry, Xiangyang Xu, Jorge O. Escobedo, Martha Sibrian-Vazquez, Lisa Wong, Corin M. Schowalter, Timothy J. Jensen, Frank R. Fronczek, Isiah M. Warner, Robert M. Strongin
Seminaphthofluorones Are A Family Of Water-Soluble, Low Molecular Weight, Nir-Emitting Fluorophores, Youjun Yang, Mark Lowry, Xiangyang Xu, Jorge O. Escobedo, Martha Sibrian-Vazquez, Lisa Wong, Corin M. Schowalter, Timothy J. Jensen, Frank R. Fronczek, Isiah M. Warner, Robert M. Strongin
Chemistry Faculty Publications and Presentations
A readily accessible new class of near infrared (NIR) molecular probes has been synthesized and evaluated. Specific fluorophores in this unique xanthene based regioisomeric seminaphthofluorone dye series exhibit a combination of desirable characteristics including (i) low molecular weight (339 amu), (ii) aqueous solubility, and (iii) dual excitation and emission from their fluorescent neutral and anionic forms. Importantly, systematic changes in the regiochemistry of benzannulation and the ionizable moieties afford (iv) tunable deep-red to NIR emission from anionic species and (v) enhanced Stokes shifts. Anionic SNAFR-6, exhibiting an unusually large Stokes …