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Articles 1 - 9 of 9
Full-Text Articles in Chemistry
Raman Spectroscopy For Forensic Identification Of Body Fluid Traces: Method Validation For Potential False Negatives Caused By Blood-Affecting Diseases, Niara Nichols
Chemistry
Two critical issues in forensic science are identifying body fluid traces found at crime scenes and preserving them for DNA analysis. However, the majority of current biochemical tests for body fluid identification, which are applicable at the crime scene, are presumptive and destructive to the sample. Raman Spectroscopy provides a suitable alternative to current methods as a nondestructive, confirmatory, and potentially in field method. Our laboratory has developed a chemometric model for the identification of five main body fluids using Raman spectroscopy. This model was developed using samples obtained from healthy donors. Thus, it is of most importance for the …
Structural Tuning And Spectroscopic Characterizations Of Polysulfide As Battery Materials, Daiqiang Liu
Structural Tuning And Spectroscopic Characterizations Of Polysulfide As Battery Materials, Daiqiang Liu
Electronic Thesis and Dissertation Repository
Polysulfide materials have drawn extensive attention for next-generation battery development since the current lithium-ion battery has almost reached its limit regarding energy density and safety issues. Many phosphorus and sodium sulfide materials have been used in different battery types, such as solid-state and sodium-sulfur batteries. However, there are still issues that prevent these techniques from applications. In recent years, there has been increasing attention on investigations of the structural and phase transformations of electrode and electrolyte materials under high pressure. Many studies have shown that external pressure can affect structural properties and influence electrical properties. In this study, three battery-related …
Visualization And Quantification Of The Laser-Induced Art Of Tio2 By Photoexcitation Of Adsorbed Dyes, Daniela (Labadini) Graf Stillfried Barreto
Visualization And Quantification Of The Laser-Induced Art Of Tio2 By Photoexcitation Of Adsorbed Dyes, Daniela (Labadini) Graf Stillfried Barreto
Graduate Masters Theses
Dye-pretreated anatase TiO2 films, commonly used as photoanodes in dye sensitized solar cells (DSSC), were utilized as a model system to investigate the laser-induced anatase to rutile phase transformation (ART), using N719 dye, N749 dye, D149 dye, and MC540 dye as photo-sensitizers. The visible lasers (532 and 785 nm) used for Raman spectroscopy were able to transform pure anatase into rutile at the laser spot when excitation of the dye sensitizer caused an electron injection from the excited state of the dye molecule into the conduction band of the TiO2. The three dyes with carboxylic acid anchor groups (N719, N749 …
The Supercam Instrument Suite On The Mars 2020 Rover: Science Objectives And Mast-Unit Description, S. Maurice, R. C. Wiens, P. Bernardi, P. Caïs, S. Robinson, T. Nelson, O. Gasnault, J. -M. Reess, M. Deleuze, F. Rull, J. -A. Manrique, S. Abbaki, R. B. Anderson, Y. André, Stanley M. Angel, G. Arana, T. Battault, P. Beck, K. Benzerara, S. Bernard, Et. Al.
The Supercam Instrument Suite On The Mars 2020 Rover: Science Objectives And Mast-Unit Description, S. Maurice, R. C. Wiens, P. Bernardi, P. Caïs, S. Robinson, T. Nelson, O. Gasnault, J. -M. Reess, M. Deleuze, F. Rull, J. -A. Manrique, S. Abbaki, R. B. Anderson, Y. André, Stanley M. Angel, G. Arana, T. Battault, P. Beck, K. Benzerara, S. Bernard, Et. Al.
Faculty Publications
On the NASA 2020 rover mission to Jezero crater, the remote determination of the texture, mineralogy and chemistry of rocks is essential to quickly and thoroughly characterize an area and to optimize the selection of samples for return to Earth. As part of the Perseverance payload, SuperCam is a suite of five techniques that provide critical and complementary observations via Laser-Induced Breakdown Spectroscopy (LIBS), Time-Resolved Raman and Luminescence (TRR/L), visible and near-infrared spectroscopy (VISIR), high-resolution color imaging (RMI), and acoustic recording (MIC). SuperCam operates at remote distances, primarily 2–7 m, while providing data at sub-mm to mm scales. We report …
Mechanism Of Action Of Dihydropteridine Reductase, Gabriela Arias De La Rosa
Mechanism Of Action Of Dihydropteridine Reductase, Gabriela Arias De La Rosa
Dissertations, Theses, and Capstone Projects
Human dihydropteridine reductase is an enzyme that transfers a hydride from NADH to reduce quinonoid 7,8-dihydropterin (qBH2) to 5,6,7,8-tetrahydropterin (BH4), which is a cofactor important in the production of neurotransmitters.DHPR deficiency causes a drastic form of the neurological genetic disease phenylketonuria (PKU) that does not benefit from a phenylalanine-free diet.From site-directed mutagenesis studies, mostly on Rat DHPR, we know that certain residues are important for cofactor binding, substrate binding, and hydride transfer; however, there are still some questions about how DHPR works, particularly, because there is not a crystal structure of the tertiary complex: What is …
Advanced Raman Spectroscopy Detection Of Oxidative Damage In Nucleic Acid Bases: Probing Chemical Changes And Intermolecular Interactions In Guanosine At Ultralow Concentration, Francesca Ripanti, Claudia Fasolato, Flavia Mazzarda, Simonetta Palleschi, Marina Ceccarini, Chunchun Li, Margherita Bignami, Enrico Bodo, Steven E.J. Bell, Filomena Mazzei, Paolo Postorino
Advanced Raman Spectroscopy Detection Of Oxidative Damage In Nucleic Acid Bases: Probing Chemical Changes And Intermolecular Interactions In Guanosine At Ultralow Concentration, Francesca Ripanti, Claudia Fasolato, Flavia Mazzarda, Simonetta Palleschi, Marina Ceccarini, Chunchun Li, Margherita Bignami, Enrico Bodo, Steven E.J. Bell, Filomena Mazzei, Paolo Postorino
Bioelectrics Publications
DNA/RNA synthesis precursors are especially vulnerable to damage induced by reactive oxygen species occurring following oxidative stress. Guanosine triphosphates are the prevalent oxidized nucleotides, which can be misincorporated during replication, leading to mutations and cell death. Here, we present a novel method based on micro-Raman spectroscopy, combined with ab initio calculations, for the identification, detection, and quantification of oxidized nucleotides at low concentration. We also show that the Raman signature in the terahertz spectral range (<100 >cm(-1)) contains information on the intermolecular assembly of guanine in tetrads, which allows us to further boost the oxidative damage detection limit. Eventually, we …
Characterizing The Presence Of Edta In Blood Samples, Alexandra Wright
Characterizing The Presence Of Edta In Blood Samples, Alexandra Wright
Master of Science in Forensic Science Directed Research Projects
Blood is often a type of evidence found at crime scenes. There has been a long history of criminal cases involving blood evidence samples that were allegedly planted at the scene by a third party. Ethylenediaminetetraacetic acid, or EDTA, is an anticoagulant that is not naturally occurring in blood samples; it chelates to ions in blood to prevent clotting. If present in a blood evidence sample, it could be indicative that the blood sample may have been planted at the crime scene to implicate a suspect. EDTA is also reported to modify clothing and exist in detergents, to allow dyes …
Utilizing Raman Spectroscopy To Determine The Time Since Deposition Of Heated Bloodstains, Alexis Pearl Barber
Utilizing Raman Spectroscopy To Determine The Time Since Deposition Of Heated Bloodstains, Alexis Pearl Barber
Legacy Theses & Dissertations (2009 - 2024)
The development of novel forensic methods is a rapidly growing area within analytical chemistry. Analytical chemistry is well suited for forensic analyses as a plethora of information can be ascertained from utilizing a wide variety of techniques. At the scene of violent crimes, bloodstain evidence is one of the most frequently found and valuable types of evidence. This is because blood is a complex biological fluid which can provide crucial information during a forensic investigation including DNA evidence. The most informative form of analysis is DNA profiling, which potentially allows for the identification of an individual. However, there is more …
The Detection And Identification Of Blood On Interfering Substrates Using Raman Spectroscopy And Hamand For Forensic Purposes, Jalissa M. Thomas
The Detection And Identification Of Blood On Interfering Substrates Using Raman Spectroscopy And Hamand For Forensic Purposes, Jalissa M. Thomas
Legacy Theses & Dissertations (2009 - 2024)
Body fluids, such as blood and semen, can provide invaluable information to a criminal investigation. As such, it is imperative that body fluid evidence is properly detected and identified. Our laboratory has developed a methodology to universally detect and identify body fluids using Raman spectroscopy and chemometrics. This methodology was developed under ideal conditions, which are rare in the field. Body fluid evidence can be found on substrates that produce a large Raman signal that can hinder detection of body fluid traces, which produce a weak signal. This project proposes the use of a statistical program called HAMAND (Hypothetical Addition …