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Articles 1 - 5 of 5
Full-Text Articles in Chemistry
Study Of Solvent-Free, Microwave-Assisted Ring-Opening Reactions Of Phenyl Glycidyl Ether With Azoles, Marygrace Mcafee, Joshua Pack, Brian Walker
Study Of Solvent-Free, Microwave-Assisted Ring-Opening Reactions Of Phenyl Glycidyl Ether With Azoles, Marygrace Mcafee, Joshua Pack, Brian Walker
Arkansas Women in STEM Conference
Literature precedent supports that microwave-assisted organic synthesis can afford fast, high-yield, and efficient synthetic pathways, often comparable to or better than traditional heating methods. Building on this, our work utilizes microwave-assisted synthesis for the epoxide ring opening of phenyl glycidyl ether through nucleophilic addition, aiming to create both pyrazole and imidazole derivatives. These heterocyclic azole compounds have been shown to be important due to their presence in many natural products, as well as their anti-fungal and other pharmacological activities. We are exploring the use of microwave irradiation under neat (solvent-free) conditions, focused on a streamlined approach to minimize time, energy …
Optimization Of The Synthesis Parameters Of Sapo-34, Adam Honchar
Optimization Of The Synthesis Parameters Of Sapo-34, Adam Honchar
Undergraduate Student Research Internships Conference
A microporous material known as SAPO-34 is a very efficient catalyst in methanol-to-olefins reactions. My project aimed to optimize synthesis parameters of SAPO-34 to reduce crystallization time in order to study the formation mechanism using In-situ NMR spectroscopy. Understanding the crystallization mechanism would allow us to make it more efficient and tailor-made to fit for other applications.
Simple Arenes As Aryne Synthetic Equivalents Via Sulfonium Salt Intermediates, Riley A. Roberts
Simple Arenes As Aryne Synthetic Equivalents Via Sulfonium Salt Intermediates, Riley A. Roberts
Student Research Symposium
Arynes are ephemeral molecules that are yet to be fully exploited in synthetic strategy because they are often challenging to access. These reactive intermediates participate in a myriad of reactions that conventional chemistry is incapable of, making them extremely useful for the synthesis of important molecules like pharmaceuticals and agrochemicals. While classical approaches for synthesizing arynes employ cheap starting material, extremely harsh reagents are necessary to generate the aryne. In contrast, methods that do not require harsh reaction conditions do require starting material that is exceedingly difficult to synthesize. To access arynes quickly and efficiently, the work described herein aims …
Evaluating The Scalability Of Graphene Synthesis, Evan Dexter
Evaluating The Scalability Of Graphene Synthesis, Evan Dexter
Scholar Week 2016 - present
Graphene is a new material, first isolated in 2004, consisting of one to a few atomic layers of carbon in a lattice sheet structure. Graphene has high tensile strength, high surface area, very low electrical resistance, and various other special properties that make it an excellent material for use in emerging technologies in the categories of electrical components, energy systems, and high strength applications. The production scale of graphene sheets and its variations is currently limited to laboratory use, with a great amount of current research going into the development of manufacturing techniques of the material. I conducted experiments to …
Microwave Assisted Synthesis Of Tri-Substituted Pyridazine Exploration, Austin Wright
Microwave Assisted Synthesis Of Tri-Substituted Pyridazine Exploration, Austin Wright
GS4 Georgia Southern Student Scholars Symposium
Pyridazines are nitrogen-containing compounds that have been found to show a number of pharmaceutical applications. They exhibit antimicrobial, antifungal, and antibacterial properties to name a few. In particular: 3,4,6-triphenylpyridazine derivatives are known to possess anticancer properties. The purpose of this project is to synthesize tri-substituted pyridazine derivatives using microwave-assisted reactions, and to check its biological applications. Microwave synthesis will help shorten reaction times and produce high, efficient yields. Various catalysts, bases, reaction times, and temperatures will be explored to study the scope of the reactions.