Chemistry Commons^™

Laser-Induced Photon-Branched Chain Reaction In A Chemically-Active Gas-Dispersed Medium, Thomas F. George, Renat R. Letfullin, Galen C. Duree

Thomas George

Tuning Nonlinear Optical Properties In Π-Delocalizable Ruthenium Complexes, T. Christopher Corkery, Sanjay S. Chavan, Marie P. Cifuentes, Marek Samoc, Stijn Van Cleuvenbergen, Inge Asselberghs, Koen Clays, Mark G. Humphrey

Chris Corkery

No abstract provided.

Adhesion And Interfacial Fracture Toughness Between Hard And Soft Materials, Nima Rahbar, Kurt Wolf, Argjenta Orana, Roy Fennimore, Zong Zong, Juan Meng, George Papandreou, Cynthia Maryanoff, Wole Soboyejo

Nima Rahbar

This paper presents the results of a combined experimental and theoretical study of adhesion between hard and soft layers that are relevant to medical devices such as drug-eluting stents and semiconductor applications. Brazil disk specimens were used to measure the interfacial fracture energies between model parylene C and 316L stainless steel over a wide range of mode mixities. The trends in the overall fracture energies are predicted using a combination of adhesion theories and fracture mechanics concepts. The measured interfacial fracture energies are shown to be in good agreement with the predictions.

Potential Driven Deposition Of Poly(Diallyldimethylammonium Chloride) Onto The Surface Of 3-Mercaptopropionic Acid Monolayers Assembled On Gold, Wesley Sanders, Mark Anderson

Mark R. Anderson

Electrochemical impedance spectroscopy (EIS) and quartz crystal microbalance (QCM) measurements are used to examine the ability of applied potential to drive the ionic self-assembly of poly(diallyldimethylammonium) chloride (PDDA) onto a substrate modified with a monolayer of 3-mercaptopropionic acid (3-MPA). The potential of zero charge (PZC) of the gold electrode modified with a monolayer of 3-MPA was found by differential capacitance measurements to be −0.12 (±0.01) V versus Ag−AgCl. Changing the substrate potential to values positive (−0.01 V vs Ag−AgCl) of the PZC induces interfacial conditions that are favorable for the electrostatic deposition of cationic polymers onto the surface of 3-MPA …

Sequence Specific And High Affinity Recognition Of 5′-Acgcgt-3′ By Rationally Designed Pyrrole-Imidazole H-Pin Polyamides: Thermodynamic And Structural Studies., Hilary Mackay, Toni Brown, Peter Uthe, Laura Westrate, Alan Sielaff, Justin Jones, James Lajiness, Jerome Kluza, Caroline O'Hare, Binh Nguyen, Zach Davis, Chrystal Bruce, W. Wilson, John Hartley, Moses Lee

Chrystal D. Bruce

Imidazole (Im) and Pyrrole (Py)-containing polyamides that can form stacked dimers can be programmed to target specific sequences in the minor groove of DNA and control gene expression. Even though various designs of polyamides have been thoroughly investigated for DNA sequence recognition, the use of H-pin polyamides (covalently cross-linked polyamides) has not received as much attention. Therefore, experiments were designed to systematically investigate the DNA recognition properties of two symmetrical H-pin polyamides composed of PyImPyIm (5) or f-ImPyIm (3e, f=formamido) tethered with an ethylene glycol linker. These compounds were created to recognize the cognate 5′-ACGCGT-3′ through an overlapped and staggered …

Impedance Of Contact-Printed Alkanethiol Self-Assembled Monolayers On Gold, Leslie Adamczyk, Mark Anderson

Mark R. Anderson

Contact printing (CP) is a common method for creating modified interfaces having two-dimensional patterns. The popularity of this method is due to the ease and low cost of this method. When printing an interfacial pattern with n-alkanethiols, the desired properties are those of a homogeneous, solution deposited monolayer. Patterning a surface, however, may cause defects to occur within the monolayer where two thiol domains meet. If large enough, the activity of these areas can dominate the electrochemical response. Creating patterned monolayer modified interfaces, therefore, may generate vast user defined domain boundaries that impact the electrochemical behavior of the modified interface …

Potential Driven Polyelectrolyte Adsorption Onto Monolayer Modified Electrodes, Mark Anderson, Weslie Sanders

Mark R. Anderson

Preparation of interfacial structures by molecular self-assembly has been actively studied for many years. Well-defined modified interfaces can be used to study fundamental interfacial properties, or they can be used in different practical applications. To broaden the utility of interfaces prepared by molecular self-assembly, monolayers containing terminal functionality are frequently used. These interfaces have structural and physical properties that can be controlled by both the identity of the functionalization as well as the ensemble structure of the modified interface. This suggests that the chemical and physical properties of an interface can be designed and/or controlled to some extent by altering …

Homogeneous Dbd In N2: 1) Lif, Talif And Electrical Measurements, N. Gherardi, Et. Es-Sebbar, C. Sarra-Bourret, N. Naudé, F. Massines

Dr. Et-touhami Es-sebbar

In this paper we compare two different discharges that can be obtained in a DBD configuration, that is to say the filamentary discharge (usual regime in atmospheric DBD) with the Atmospheric Pressure Townsend Discharge (APTD), which is a homogeneous regime obtained in nitrogen atmosphere. The aim is to help in the understanding of the processes which control the transition from one regime to the other. To do so, the discharge is characterized through electrical measurements, coupled with optical diagnostics among which Laser Induced Fluorescence (LIF) for radical density measurements. The influence of the addition of small quantities of additives on …

Synthesis Of Large Crystal Transition Metal Substituted Zeolite Zsm-5, Tara L. Schaeffer, Scott Kirkby

Scott J. Kirkby

Potential Driven Polyelectrolyte Adsorptoin Onto Monolayer Modified Electrodes, Mark Anderson

Mark R. Anderson

No abstract currently available.

Green Separations Using Ionic Liquids, Samuel Morton

Samuel A Morton

No abstract provided.

Oscillating Regime In Carbonylation Reaction Of Propargyl Alcohol (In Russian), Sergey N. Gorodsky, Anatoly V. Kurdiukov, Oleg N. Temkin

Sergey N. Gorodsky

No abstract provided.

Active Species Generation Of Homogeneous Dbd In N2: Experiment And Modelling, N. Gherardi, Et. Es-Sebbar, C. Sarra-Bourret, N. Naudé, F. Massines, D. Tzyganov, P. Ségur, S. Pancheshnyi

Dr. Et-touhami Es-sebbar

No abstract provided.

Metallomesogens: Supramolecular Design Via Alkyl-Rich Metal Complexes, Juan C. Noveron

Juan C N

Molecules that use non-covalent interactions to self-organize into supramolecular structures have the potential to generate functional materials with a broad range of applications. This review article focuses on the design and synthesis of molecules that use transition metal ions and long alkyl chains to direct the formation of ordered supramolecular phases. This unique combination of coordination bonds and alkyl interdigitation provide exceptional control over intermolecular interactions and can generate nanoscale molecular order as liquid crystalline states, Langmuir-Blodgett films on surfaces, highly ordered lyotropic phases such as metallo-micelles in water and reverse metallo-micelles in organic media. The synthetic strategy for alkane-rich …

The Discovery-Oriented Approach To Organic Chemistry. 7. Rearrangement Of Trans-Stilbene Oxide With Bismuth Trifluoromethanesulfonate And Other Metal Triflates, Ram S. Mohan, James E. Christensen, Matthew G. Huddle, Jamie L. Rogers, Herbie Yung

Ram S. Mohan

Surface Ion-Electron Recombination As The Main Source Of Atoms In Flowing N2 Dbd, D. Tsyganov, Et. Es-Sebbar, S. Pancheshnyi, N. Gherardi, P. Ségur, F. Massines

Dr. Et-touhami Es-sebbar

No abstract provided.

Talif Quantification Of Nitrogen Atoms Applied To Experimental Simulation Of Titan’S Atmosphere, Et. Es-Sebbar, Y. Benilan, E. Arzoumanian, M.-C. Gazeau

Dr. Et-touhami Es-sebbar

No abstract provided.

S.E.T.U.P., A New Program Of Representative Simulations Of Titan’S Atmosphere: Current Status, M-C. Gazeau, E. Arzoumanian, Y. Benilan, Et. Es-Sebbar, A. Jolly, S. Perrier, C. Romanzin

Dr. Et-touhami Es-sebbar

No abstract provided.

Characterization Of Carboxylic Acid-Terminated Self-Assembled Monolayers By Electrochemical Impedance Spectroscopy And Scanning Electrochemical Microscopy, Wesley Sanders, Ricardo Vargas, Mark Anderson

Mark R. Anderson

Electrochemical impedance spectroscopy (EIS) and scanning electrochemical microscopy (SECM) are used to monitor changes in the ionization of monolayers of 11-mercaptoundecanoic acid. When using an anionic redox probe, Fe(CN)6−4, the charge-transfer resistance of the 11-mercaptoundecanoic acid monolayer-modified interface increases in a sigmoidal fashion as the solution is made basic. The opposite effect is observed when using a cationic redox probe. The inflection points of these two titration curves, however, differ when using the different redox probes. This result is taken as being characteristic of the influence that applied potential has on the ionization of the monolayer. The role of substrate …

Comparison Of Townsend Dielectric Barrier Discharge In N2, N2/O2 And N2/N2o: Behavior And Density Of Radicals, F. Massines, Et. Es-Sebbar, N. Gherardi, N. Naudé, D. Tsyganov, P. Ségur, S. Pancheshnyi

Dr. Et-touhami Es-sebbar

No abstract provided.

Writing Research Proposal: Literature Review And Database Search, Mamoudou H. Dicko Prof.

Pr. Mamoudou H. DICKO, PhD

Modifying The N-Terminus Of Polyamides: Pyimpyim Has Improved Sequence Specificity Over F-Impyim, Toni Brown, Hilary Mackay, Mark Turlington, Arden Sutterfield, Traci Smith, Alan Sielaff, Laura Westrate, Chrystal Bruce, Jerome Kluza, Caroline O'Hare, Binh Nguyen, W. Wilson, John Hartley, Moses Lee

Chrystal D. Bruce

Seven N-terminus modified derivatives of a previously published minor-groove binding polyamide (f-ImPyIm, 1) were synthesized and the biochemical and biophysical chemistry evaluated. These compounds were synthesized with the aim of attaining a higher level of sequence selectivity over f-ImPyIm (1), a previously published strong minor-groove binder. Two compounds possessing a furan or a benzofuran moiety at the N-terminus showed a footprint of 0.5μM at the cognate ACGCGT site (determined by DNase I footprinting); however, the specificity of these compounds was not improved. In contrast, PyImPyIm (4) produced a footprint of 0.5μM but showed a superior specificity using the same technique. …

Simultaneous Determination Of Glucose And L‐Glutamate Using A Capillary Enzyme Reactor With Electrochemical Detection, Stephanie Hooper, Mark Anderson

Mark R. Anderson

An electrophoresis capillary that incorporates two enzymes for the simultaneous determination of glucose and l-glutamate is described. The enzymes deposited along the separation capillary walls react with their respective substrate as they are separated during the electrophoresis to produce hydrogen peroxide that is detected by amperometry as the hydrogen peroxide zone emerges from the end of the capillary. Even though both enzyme reactions produce a common product, hydrogen peroxide, the hydrogen peroxide produced by each enzyme reaction stays in narrow zones that migrate the length of the capillary at different rates. The rate of migration for the individual H2O2 zones …

Dioxidobis(2-Oxo-1,2-Dihydropyridin-3-Olato)­Molybdenum(Vi), Manoj Trivedi, Daya Shankar Pandey, Nigam P. Rath

Nigam Rath

Diethyl 2-[(4-Nitro­Phen­Yl)(4-Phenyl-1,2,3-Selenadiazol-5-Yl)Meth­Yl]Malonate, A. Marx, S. Saravanan, S. Muthusubramanian, V. Manivannan, Nigam P. Rath

Nigam Rath

The Development Of Novel Therapeutics For Sickle-Cell Disease, Brian Brennan, Sara Costello, '10, Steven Sturlis, '10

Brian B. Brennan

No abstract provided.

The Expression Of Recombinant Hemoglobin In Escherichia Coli, Brian Brennan, Christopher Miedema, '10, Evan Mason, '10

Brian B. Brennan

No abstract provided.

Expanding The Range Of Halogenated 1′-Methyl-1,2′-Bipyrroles (Mbps) Using Gc/Ecni-Ms And Gc × Gc/Tof-Ms, Kristin Pangallo, Robert K. Nelson, Emma L. Teuten, Emma L. Teuten, Byron E. Pedler, Christopher M. Reddy

Kristin Pangallo

Manipulating Interfacial Structure And Properties, Mark Anderson

Mark R. Anderson

No abstract is available at this time.

Second-Sphere Amino Acids Contribute To Transition-State Structure In Bovine Purine Nucleoside Phosphorylase, Lei Li, Minkui Luo, Mahmoud Ghanem, Erika A. Taylor, Vern L. Schramm

Erika A. Taylor, Ph.D.

Transition-state structures of human and bovine of purine nucleoside phosphorylases differ, despite 87% homologous amino acid sequences. Human PNP (HsPNP) has a fully dissociated transition state, while that for bovine PNP (BtPNP) has early SN1 character. Crystal structures and sequence alignment indicate that the active sites of these enzymes are the same within crystallographic analysis, but residues in the second-sphere from the active sites differ significantly. Residues in BtPNP have been mutated toward HsPNP, resulting in double (Asn123Lys; Arg210Gln) and triple mutant PNPs (Val39Thr; Asn123Lys; Arg210Gln). Steady-state kinetic studies indicated unchanged catalytic activity, while pre-steady-state studies indicate that the chemical …