Physical Sciences and Mathematics Commons^™

Perovskite Materials In X-Ray Detection And Imaging: Recent Progress, Challenges, And Future Prospects, Md Helal Miah, Mayeen U. Khandaker, Mohammad A. Islam, Mohammad Nur-E-Alam, Hamid Osman, Md Habib Ullah

Research outputs 2022 to 2026

Perovskite materials have attracted significant attention as innovative and efficient X-ray detectors owing to their unique properties compared to traditional X-ray detectors. Herein, chronologically, we present an in-depth analysis of X-ray detection technologies employing organic-inorganic hybrids (OIHs), all-inorganic and lead-free perovskite material-based single crystals (SCs), thin/thick films and wafers. Particularly, this review systematically scrutinizes the advancement of the diverse synthesis methods, structural modifications, and device architectures exploited to enhance the radiation sensing performance. In addition, a critical analysis of the crucial factors affecting the performance of the devices is also provided. Our findings revealed that the improvement from single crystallization …

Aging An Ancient Maya Population From Actuncan, Belize Using Dental X-Rays, Kaitlyn Nicole Cash

Honors Theses

My goal is to determine an accurate age at death estimation of an ancient Maya population from the archaeological site of Actuncan, Belize. This was done by measuring the lengths of the coronal pulp cavities in the individuals’ teeth. I used X-Ray images to measure the coronal pulp cavities of the teeth and estimated age using multiple regression formulae for premolars, molars, and incisors to make age estimations. The formulae came from two studies, Ikeda et al. (1985) and Drusini (2008), that form the basis of my research. Ikeda et al. (1985) was the first to use this aging method, …

Selectively Modified Lactose And N-Acetyllactosamine Analogs At Three Key Positions To Afford Effective Galectin-3 Ligands †, Shuay Abdullayev, Priyanka Dipak Kadav, Purnima Bandyopadhyay, Francisco Javier Medrano, Gabriel A. Rabinovich, Tarun K. Dam, Antonio Romero, René Roy

Michigan Tech Publications

Galectins constitute a family of galactose-binding lectins overly expressed in the tumor microenvironment as well as in innate and adaptive immune cells, in inflammatory diseases. Lactose ((β-D-galactopyranosyl)-(1→4)-β-D-glucopyranose, Lac) and N-Acetyllactosamine (2-acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LacNAc) have been widely exploited as ligands for a wide range of galectins, sometimes with modest selectivity. Even though several chemical modifications at single positions of the sugar rings have been applied to these ligands, very few examples combined the simultaneous modifications at key positions known to increase both affinity and selectivity. We report herein combined modifications at the anomeric position, C-2, and O-3′ of each of the two …

Single-Shot, Ultrafast, Multi-Frame X-Ray Imaging Of Defect-Bearing Ablator Materials In Extreme Conditions, Daniel S. Hodge

Theses and Dissertations

Characterization of the dynamic behavior of defect-bearing ablator materials subjected to extreme conditions is essential in advancing fusion energy as an reliable and abundant energy source. By understanding how materials evolve spatially and temporally we can minimize hydrodynamic instabilities, which are major contributing factors to energy yield degradation in inertial confinement fusion (ICF) experiments. In this thesis we demonstrate the capabilities of an ultrafast x-ray imaging (UXI) detector, the Icarus V2, where we capture multiple frames of single void-bearing sample compressed by a high-intensity laser shockwave. Using the Matter in Extreme Conditions (MEC) instrument at the Linac Coherent Light Source …

Emergent Spectra Of Young X-Ray Emitting Populations Across Environments, Alex Siebenmorgen

Physics Undergraduate Honors Theses

We construct reasonably accurate models of the X-Ray spectra of a multitude of sources in M51. We construct both average and individual models for the sources, which are split into 16 groups as the counts per source increases. Then, we create a plot to show how the model-predicted values of column density (nH) and photon index (gamma) change with luminosity. These models will be used to create an accurate X-Ray stellar energy distribution (SED) for M51, and to better understand how the SED changes with environmental factors like metallicity and star formation rate (SFR).

Synthesis And Advanced Characterization Of Energy Materials, Erik Sarnello

Graduate Research Theses & Dissertations

Catalysts are used in an extremely broad range of systems including everything from biological systems to industrial processes. An ideal catalyst offers robust stability and high activity. This work focuses on the synthesis and characterization of materials that show promise in the field of catalysis. Advanced synchrotron characterization techniques and unique experimental design are highlighted to provide foundation work that will provide the necessary information to aid in designing and fabricating catalytic materials. Supported metal nanoparticle (SMN) catalysts are enormously crucial for many catalytic applications. However, catalyst deactivation, caused by sintering and coke formation, is a ubiquitous problem that significantly …

Smart Covid-3d-Scnn: A Novel Method To Classify X-Ray Images Of Covid-19, Ahed Abugabah, Atif Mehmood, Ahmad Ali Al Zubi, Louis Sanzogni

All Works

The outbreak of the novel coronavirus has spread worldwide, and millions of people are being infected. Image or detection classification is one of the first application areas of deep learning, which has a significant contribution to medical image analysis. In classification detection, one or more images (detection) are usually used as input, and diagnostic variables (such as whether there is a disease) are used as output. The novel coronavirus has spread across the world, infecting millions of people. Early-stage detection of critical cases of COVID-19 is essential. X-ray scans are used in clinical studies to diagnose COVID-19 and Pneumonia early. …

Synthesis, Characterization, Computational Analyses, In Silico Admet Studies, And Inhibitory Action Against Sars-Cov-2 Main Protease (Mpro) Of A Schiff Base, Songül Şahi̇n, Necmi̇ Dege

Turkish Journal of Chemistry

COVID-19 disease caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2) has struck the whole world and raised severe health, economic, and social problems. Many scientists struggled to find a vaccine or an antiviral drug. Eventually, both vaccines and recommended drugs, repurposed drugs, or drug combinations were found, but new strains of SARS-CoV-2 continue to threaten human life and health. As part of the fight against COVID-19 disease, this study involves an in silico molecular docking analysis on the main protease (Mpro) of SARS-CoV-2. To this aim, a Schiff base compound was synthesized and characterized using spectroscopic techniques, including X-ray, …

Therapy And Medical Imaging Applications Of Focusing Polycapillary X-Ray Optics, Weiyuan Sun

Legacy Theses & Dissertations (2009 - 2024)

Focusing polycapillary optics yield high gains in intensity and increased spatial resolution for a variety of clinical, lab-based, synchrotron, or in situ analysis applications. In this dissertation we investigate the extension of two applications of focusing polycapillary optics. The first is the application of polycapillary optics in radiation therapy. This discussion includes measurements and calculation of dose for focused beam orthovoltage therapy. A system has been designed to investigate whether the polycapillary optics can produce an X-ray beam which can give more accurate dose painting due to the higher dose concentration at the focal spot. X-ray exposures were measured with …

Attention-Based End-To-End Cnn Framework For Content-Based X-Ray Imageretrieval, Şaban Öztürk, Adi Alhudhaif, Kemal Polat

Turkish Journal of Electrical Engineering and Computer Sciences

The widespread use of medical imaging devices allows deep analysis of diseases. However, the task of examining medical images increases the burden of specialist doctors. Computer-assisted systems provide an effective management tool that enables these images to be analyzed automatically. Although these tools are used for various purposes, today, they are moving towards retrieval systems to access increasing data quickly. In hospitals, the need for content-based image retrieval systems is seriously evident in order to store all images effectively and access them quickly when necessary. In this study, an attention-based end-to-end convolutional neural network (CNN)framework that can provide effective access …

Modeling The Obscuring Features In Active Galactic Nuclei: An X-Ray Analysis Of Ngc 1052, Samantha E. Cabral

Graduate Masters Theses

We present a multi-epoch analysis of the X-ray spectrum of NGC 1052, a nearby galaxy notorious for its well-studied spectral variability. We utilize observations from NuSTAR, XMM-Newton, Chandra, Swift, Suzaku, BeppoSAX, and ASCA to create a comprehensive set of data that spans roughly 20 years. Organizing our data by observation date and grouping into specific epochs allows us to explore a model allowed to flex and accommodate any spectral changes that occur over time in the X-ray spectrum of NGC 1052. We find that the spectrum takes on a relatively flat nature and is best modeled with two neutral absorption …

The Crystal Structure Of (Cuxzn1-X)0:456in1:084ge0:46o3 (Cuzigo) Using Neutron And X-Ray Diffraction, Boluwatife A. Adekoya

College of Science and Health Theses and Dissertations

The solid solution (CuxZn(1-x))0.456In1.084Ge0.46O3 (CuZIGO) has a complex structure where zinc and copper partially occupy a site shared by indium and germanium. ZIGO, the x = 0 endpoint, is a potential transparent conducting oxide (TCO) with similar conductivity and transparency to cubic In2O3, which, when doped with Sn4+, is the most prevalent TCO. ZIGO structure possesses a tetragonal structure and has the ability to produce multiple new phases with an array of properties that are beneficial to identify and understand. Analyzing this structure is best done through chemical substitution to identify the newly produced phases. Copper is a suitable choice …

2-(Di­Phenyl­Methyl­Idene)-2,3-Di­Hydro-1h-Inden-1-One, Tao Zhang, Vilmar Bandero, Tom Mccabe, Neil Frankish, Helen Sheridan

Articles

In the title mol­ecule, C₂₂H₁₆O, the indanone ring system is approximately planar with a dihedral angle between the fused rings of 5.13 (14)°. Two benzene rings are linked together at one side of a double bond, sitting on either side of the indanone ring system and making dihedral angles of 70.30 (12) and 44.74 (13)° with it. In the crystal, hydrogen bonding is not present, but weak C—H⋯π or π–π inter­actions occur and mol­ecules form a sheet-like structure in the bc plane.

Laser Surface Cleaning As A Novel Approach For Genesis Solar Wind Collectors, Martina Schmeling, I. V. Veryovkin, C. E. Tripa

Chemistry: Faculty Publications and Other Works

A new surface cleaning method utilizing lasers has been evaluated for its suitability to Genesis solar wind collectors

Nucleophilic Substitution Reactions Of Monofunctional Nucleophilic Reagents Withcyclotriphosphazenes Containing 2,2-Dioxybiphenyl Units, Esra Tanriverdi̇ Eçi̇k, Hani̇fe İbi̇şoğlu, Gönül Yeni̇lmez Çi̇ftçi̇, Gi̇zem Demi̇r, Eda Erdemi̇r, Fatma Yüksel

Turkish Journal of Chemistry

The nucleophilic substitution reactions of mono- and bis-spiro-2,2' -dioxybiphenyl cyclotriphosphazenes (3 and 4) with cyclopropanemethylamine (5) and aniline (6) were performed in the presence of trimethylamine in THF. Five novel cyclopropanemethylamino- and anilino-substituted spiro-2,2' -dioxybiphenyl cyclotriphosphazene derivatives (7-11) were obtained from these reactions. The molecular structures of the new cyclotriphosphazene derivatives (7- 11) were characterized by elemental analysis, MALDI-TOF MS, FT-IR, and NMR ( $^{31}$P and $^{1}$H) spectroscopies. The structure of the spiro-(2,2' -dioxybiphenyl)-bis-(anilino)-cyclotriphosphazene (11) was also determined by single-crystal X-ray crystallography.

Outlier Profiles Of Atomic Structures Derived From X-Ray Crystallography And From Cryo-Electron Microscopy, Lin Chen, Jing He, Angelo Facchiano

Computer Science Faculty Publications

Background: As more protein atomic structures are determined from cryo-electron microscopy (cryo-EM) density maps, validation of such structures is an important task. Methods: We applied a histogram-based outlier score (HBOS) to six sets of cryo-EM atomic structures and five sets of X-ray atomic structures, including one derived from X-ray data with better than 1.5 Å resolution. Cryo-EM data sets contain structures released by December 2016 and those released between 2017 and 2019, derived from resolution ranges 0–4 Å and 4–6 Å respectively. Results: The distribution of HBOS values in five sets of X-ray structures show that HBOS is sensitive distinguishing …

Palladium Complexes Bearing Κ²-N,N And Κ³-N,N,O Pendant Amine Bis(Phenolate) Ligands, Brendan J. Graziano, Eric M. Collins, Nathaniel C. Mccutcheon, Claire L. Griffith, Nicole M. Braunscheidel, Trilisa M. Perrine, Bradley M. Wile

Chemistry and Biochemistry Faculty Scholarship

The synthesis and characterization of ten new palladium(II) amine bis(phenolate) complexes is reported. Solution and single-crystal X-ray diffraction studies reveal the presence of both κ²-N,N and κ³-N,N,O binding modes in these square planar complexes. For complexes with sterically less demanding phenolate donors, addition of external acidic or basic reagents allows for the selective masking of a coordination site at Pd. Complexes bearing bulky cumyl substituents on phenolate donors exhibited unusual ¹H NMR spectroscopic features that are consistent with an anagostic interaction with the palladium center. Computational analysis …

Why Protein Conformers In Molecular Dynamics Simulations Differ From Their Crystal Structures: A Thermodynamic Insight, Fi̇li̇ppo Pullara, Mao Wenzhi, Mert Gür

Turkish Journal of Chemistry

Conformers generally deviate structurally from their starting X-ray crystal structures early in molecular dynamics (MD) simulations. Studies have recognized such structural differences and attempted to provide an explanation for and justify the necessity of MD equilibrations. However, a detailed explanation based on fundamental physics and validation on a large ensemble of protein structures is still missing. Here we provide the first thermodynamic insights into the radically different thermodynamic conditions of crystallization solutions and conventional MD simulations. Crystallization solution conditions can lead to nonphysiologically high ion concentrations, low temperatures, and crystal packing with strong specific protein--protein interactions, not present under physiological …

Cationic Ruthenium Complexes In Catalysis: The Activation Of Propargylic Alcohols Through Electronically Tuned Complexes, Matthew James Stark

Dissertations

With increasing complexity of metal complexes, it is of worthwhile interest to pursue systematic examinations of ligand modifications to study their impact on the reactivity of a catalyst. To that end, this study aimed to understand the effect electron-withdrawing ligands conveyed to catalytic activity in the etherification of propargylic alcohols and related reactions. A number of half-sandwich ruthenium complexes bearing ligands with varying electron–withdrawing properties were synthesized and structurally characterized. Their electronic and structural properties were investigated utilizing X-ray crystallography, revealing that the series of complexes did not vary significantly in structure. The complexes were studied electronically with cyclic voltammetry, …

Luminous And Obscured Quasars And Their Host Galaxies, Agnese Del Moro, David M. Alexander, Franz E. Bauer, Emanuele Daddi, Dale D. Kocevski, Flora Stanley, Daniel H. Mcintosh

Physics and Astronomy Faculty Publications

The most heavily-obscured, luminous quasars might represent a specific phase of the evolution of the actively accreting supermassive black holes and their host galaxies, possibly related to mergers. We investigated a sample of the most luminous quasars at z ≈ 1 − 3 in the GOODS fields, selected in the mid-infrared band through detailed spectral energy distribution (SED) decomposition. The vast majority of these quasars (~80%) are obscured in the X-ray band and ~30% of them to such an extent, that they are undetected in some of the deepest (2 and 4 Ms) Chandra X-ray data. Although no clear relation …

Structure Of The Ambrosia Beetle (Coleoptera: Curculionidae) Mycangia Revealed Through Micro-Computed Tomography, You Li, Yongying Ruan, Matthew T. Kasson, Edward L. Stanley, Conrad P.D.T Gillett, Andrew J. Johnson, Mengna Zhang, Jiri Hulcr

Faculty & Staff Scholarship

Ambrosia beetles (Coleoptera: Curculionidae: Scolytinae and Platypodinae) rely on a symbiosis with fungi for their nutrition. Symbiotic fungi are preserved and transported in specialized storage structures called mycangia. Although pivotal in the symbiosis, mycangia have been notoriously difficult to study, given their minute size and membranous structure. We compared the application of novel visualization methods for the study of mycangia, namely micro-computed tomography (micro-CT) and laser ablation tomography (LATscan) with traditional paraffin sectioning. Micro-CT scanning has shown the greatest promise in new organ discovery, while sectioning remains the only method with sufficient resolution for cellular visualization. All three common types …

Characterizing Decaying Dark Matter: X-Ray Emission From Sterile Neutrinos, Murat Hüdaverdi̇

Turkish Journal of Physics

Recently, an unknown emission line at E $\sim$3.5 keV from several astrophysical objects has been detected. The line is suggested to be originating from decaying dark matter particles. The results have drawn great attention from the astrophysics and particle physics community. Since the detected line is significantly weak there has also been a long debate over the origin of this mysterious signal. The most accepted scenario is a radiatively decaying sterile neutrino of 7.1 keV in mass producing a monochromatic 3.5 keV line, which is observable in X-ray energy ranges. The problem has not been settled and further observations from …

An Investigation Of Atomic Structures Derived From X-Ray Crystallography And Cryo-Electron Microscopy Using Distal Blocks Of Side-Chains, Lin Chen, Jing He, Salim Sazzed, Rayshawn Walker

Computer Science Faculty Publications

Cryo-electron microscopy (cryo-EM) is a structure determination method for large molecular complexes. As more and more atomic structures are determined using this technique, it is becoming possible to perform statistical characterization of side-chain conformations. Two data sets were involved to characterize block lengths for each of the 18 types of amino acids. One set contains 9131 structures resolved using X-ray crystallography from density maps with better than or equal to 1.5 Å resolutions, and the other contains 237 protein structures derived from cryo-EM density maps with 2-4 Å resolutions. The results show that the normalized probability density function of block …

Synthesis, Structural Characterization And Catalytic Activity Of Indenyl Complexes Of Ruthenium Bearing Fluorinated Phosphine Ligands, Matthew J. Stark, Michael J. Shaw, Arghavan Fadamin, Nigam P. Rath, Eike B. Bauer

SIUE Faculty Research, Scholarship, and Creative Activity

The synthesis, characterization and catalytic activity of new ruthenium complexes of fluorinated triarylphosphines is described. The new ruthenium complexes [RuCl(ind)(PPh₃){P(p-C₆H₄CF₃)₃}] and [RuCl(ind)(PPh₃){P(3,5-C₆H₃(CF₃)₂)₃}] were synthesized in 57% and 24% isolated yield, respectively, by thermal ligand exchange of [RuCl(ind)(PPh₃)₂], where ind = indenyl ligand η⁵-C₉H₇⁻. The electronic and steric properties of the new complexes were studied through analysis of the X-ray structures and through cyclic voltammetry. The …

On The Contribution Of The 6.7 Kev Line Emission Of The Algol Binary System To The 6.7 Kev Line Emission From The Galactic Ridge, Ambrose Chukwudi Eze, Romanus Nwachukwu Chijioke Eze, Sudum Esaenwi

Turkish Journal of Physics

We carried out spectroscopic analysis of the extracted stellar flare of the Algol binary system observed using the Suzaku satellite (OBSID: 401093010), and resolved a strong 6.7 keV line emission. The 6.7 keV line emission of the Algol binary system is similar to the 6.7 keV line of the galactic ridge X-ray emission (GRXE). The equivalent width (EW) compared favorably with the EW of the 6.7 keV emission line obtained from different galactic ridge regions. In the galaxy, we have a reasonable number of Algol binary systems and many other stars as strong coronal X-ray emitters characterized by frequent quiescent …

Estimating Length Statistics Of Aggregate Fried Potato Product Via Electromagnetic Radiation Attenuation, Jesse Lovitt

Boise State University Theses and Dissertations

This work investigates the feasibility of using non-destructive testing, in particular radiation tomography, to recover length statistics from aggregates of fried batonnet cut potato. Non-destructive testing comprises a variety of useful techniques for determining properties of an object that might otherwise require altering or destroying the object physically. Tomography is a common form of non-destructive testing used primarily to infer properties internal to an object. This process involves exposing the object of interest to radiation and detecting the quantity of radiation energy that penetrates the object, usually resulting in a grey scale image.

To do this, an artificial data pipeline …

Manipulation Of Beams Of Ultra-Relativistic Electrons To Create Femtosecond X-Ray Pulses, Jordan T. O'Neal, Austin Schulte, Rafal Rakowski, Matthias Fuchs

UCARE Research Products

The research proposed here is expected to result in a crucial component used in a next-generation X-ray source. Typical conventional high-brightness X-ray sources (so-called synchrotron lightsources) are up to 30 football fields in size. Our group uses a novel technique based on ultrahigh-power lasers to develop a similar source that can readily fit into a single, university-scale laboratory. More specifically, the research conducted within this proposal will be concerned with the manipulation of beams of ultra-relativistic electrons, (electrons that move with almost the speed of light) with the goal to focus the particles into an area that is smaller than …

Synthesis And Structural Properties Of $N$-3,4-(Dichlorophenyl)-3-Oxo-3- Phenyl-2-(Phenylcarbonyl)Propanamide And Its Cu(Ii) Complex, Ahmet Oral Sarioğlu, Tuğba Taşkin Tok, Mehmet Akkurt, Muhammad Nawaz Tahir, Mehmet Sönmez

Turkish Journal of Chemistry

A new N-carboxamide compound (3) was synthesized by the reaction of dibenzoylaceticacid-$N$-carboxyethyla\-mide (1) and 3,4-dichloroaniline (2). The $N$-(3,4-dichlorophenyl)-3-oxo-3-phenyl-2-(phenylcarbonyl) propanamide (3) subsequently reacted with Cu salt to produce its Cu(II) complex compound (4). The compounds were characterized by analytical and spectral methods. In addition, X-ray diffraction was performed to characterize and obtain detailed information about the structure of 3. The fully optimized geometries of compounds 3 and 4 were calculated at different basis sets by using the Gaussian09 (G09) software to investigate their 3D geometries and electronic structures. Comparisons between the calculated and experimental data including molecular structures, fundamental vibrational modes, …

The Role Of Cold Gas In Low-Level Supermassive Black Hole Activity, Erik D. Alfvin

Macalester Journal of Physics and Astronomy

The nature of the relationship between low-level supermassive black hole activity and galactic cold gas, if any, is currently unclear. It has been hypothesized that feedback may heat or expel gas and quench star formation; alternatively, central black holes may feed at higher rates (either directly or as a secondary effect from stellar winds) in gas-rich galaxies. We use a combination of radio data from the on-going ALFALFA survey and from the literature, along with archival X-ray flux measurements from the Chandra X-ray observatory, to investigate this potential relationship. We construct a sample of 136 late-type galaxies, with MB < −18 out to 50 Mpc, that have both HI masses and sensitive X-ray coverage. Of these, 76 host a nuclear X-ray source, a 56% detection fraction. There is a highly significant correlation between LX and Mstar with a slope of 1.5±0.2, and a tentative correlation (significant at the 2.5σ level) between LX and MHI. However, a joint fit to LX as a function of both Mstar and MHI finds no significant dependence on MHI, and similarly the residuals of LX − LX(Mstar) show no trend with MHI. We conclude that the galaxy-wide cold gas content in these spirals does not strongly influence their low-level supermassive black hole activity.

Control Of Radiation Exposure To Paediatric Patients At Conventional Radiology And Cardiac Centers At Dubai Hospital, Najlaa Khalfan Saeed Almazrouei

Theses

In view of increasing the number of x-ray examinations over the years, paediatric radiation safety is considered as one of the critical subjects in the modern medical imaging. Paediatric patients are at higher risk from ionizing radiation than adults if they receive same amount of dose. This project was conducted to evaluate paediatric patient radiation dose levels in digital radiology (both fixed and mobile x-ray units) and interventional cardiology at Dubai Hospital. The results of this study are expected to contribute in establishing local and national diagnostic reference levels in United Arab Emirates (UAE). A combination of phantom studies and …