Physical Sciences and Mathematics Commons^™

Quantification Of Dye Degradation On Titanium Dioxide-Based Membranes, Elizabeth Carol Wood

Graduate Theses and Dissertations

The purpose of this study was to examine the dye degradation on the titanium dioxide (TiO2)-based membranes. While many studies have shown photocatalytic degradation of dye on TiO2 in solution, few studies have been reported on the solid TiO2 substrate. In this work, a new method is developed to quantify the dye degradation on TiO2-based membranes. A hydrothermal method is used to synthesize the photocatalytic TiO2 nanofibers; vacuum filtration is applied to fabricate a self-assembled membrane. Silver is incorporated into the nanofibers through in situ reduction before vacuum filtration to fabricate Ag/TiO2 membrane in an attempt to red shift the …

Shallow Groundwater Distributions And Changes With Sea Level Rise In Seattle, Washington, Taylor L. Watson

Graduate Theses and Dissertations

Sea level rise (SLR) associated hazards, such as coastal flooding and erosion, are pressing issues of great concern for coastal communities across the globe. Shallow and emergent groundwater can contribute to groundwater hazards such as flooding, landslides, or damage to shallow infrastructure. This study investigates the shallow groundwater within Seattle, Washington, and projects how it will respond to SLR using interpolation and numerical groundwater modeling methods. Then, a geologic modeling method is presented as a preliminary investigation of heterogeneity and anisotropy within the aquifer system. In the results for the present-day interpolation, ~6 % of the coastal buffer –the total …

Geochemistry Of Metal-Rich Black Shales And Their Genetic Relationship To Mississippi Valley-Type Pb-Zn Ore Deposits, Midcontinent U.S., Noah S. Morris

Graduate Theses and Dissertations

The formation of Mississippi Valley-type (MVT) lead-zinc (Pb-Zn) ores is complex, involving an interaction of tectonic compression, hydrothermal fluid migration, and geochemical processes within the subsurface. Fundamental questions regarding this interaction remain unclear, including the source(s) of the Pb and Zn ions that make up the ores. A genetic link between black shales and MVT ores has been thought to exist because of (1) the presence of mature hydrocarbon and brine fluid inclusions within many MVT ores, (2) the association of the hydrothermal fluids that are linked to MVT ore formation with organic compounds and oil-like droplets, and (3) the …

Bayesian Learning Of Spatiotemporal Source Distribution For Beached Microplastic In The Gulf Of Mexico, David Pojunas

Graduate Theses and Dissertations

Over the last several decades, plastic waste has gradually accumulated while slowly degrading in terrestrial and oceanic environments. Recently, there has been an increased effort to identify the possible sources of plastic to understand how they affect vulnerable beaches. This issue is of particular concern in the Gulf of Mexico due to the presence of oil, natural gas, and plastic production. In this thesis, we expand upon existing Bayesian plastic attribution models and develop a rigorous statistical framework to map observed beached microplastics to their sources. Within this framework, we combine Lagrangian backtracking simulations of floating particles using nurdle beaching …

Maximum Depositional Age Analysis Using Paired La-Icp-Ms And Ca-Id-Tims Detrital Zircon U-Pb Geochronology, Benjamin L. Howard

Graduate Theses and Dissertations

The “law of detrital zircons” states that a sedimentary unit cannot be older than its youngest detrital zircon. The youngest U-Pb date(s) from detrital zircon may thus be used to infer a given sedimentary deposit’s maximum depositional age (MDA). MDAs may be calculated in various ways using dates from zircon U-Pb geochronology. Common dating methods used for U-Pb geochronology are laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) and chemical abrasion-isotope dilution-thermal ionization mass spectrometry (CA-ID-TIMS), a low- and high-resolution instrument type, respectively. Chapter 2 will systematically compare paired LA-ICP-MS and CA-ID-TIMS dates from the same zircon grains to assess the agreement …

Data-Centric Image Super-Resolution In Magnetic Resonance Imaging: Challenges And Opportunities, Mamata Shrestha

Graduate Theses and Dissertations

Super-resolution has emerged as a crucial research topic in the field of Magnetic Resonance Imaging (MRI) where it plays an important role in understanding and analysis of complex, qualitative, and quantitative characteristics of tissues at high resolutions. Deep learning techniques have been successful in achieving state-of-the-art results for super-resolution. These deep learning-based methods heavily rely on a substantial amount of data. Additionally, they require a pair of low-resolution and high-resolution images for supervised training which is often unavailable. Particularly in MRI super-resolution, it is often impossible to have low-resolution and high-resolution training image pairs. To overcome this, existing methods for …

Multi-Layer Evolution Of Acoustic-Gravity Waves And Ionospheric Disturbances Over The United States After The 2022 Hunga Tonga Volcano Eruption, P. A. Inchin, A. Bhatt, S. A. Cummer, S. D. Eckermann, B. J. Harding, J. Ma, J. J. Makela, J B. Snively

Publications

e Hunga-Tonga Hunga-Ha'apai volcano underwent a series of large-magnitude eruptions that generated in the atmosphere. We investigate the spatial and temporal evolutions of fluctuations driven by atmospheric acoustic-gravity waves (AGWs) and, in particular, the Lamb wave modes in high spatial resolution data sets measured over the Continental United States (CONUS), complemented with data over the Americas and the Pacific. Along with >800 barometer sites, tropospheric observations, and Total Electron Content data from >3,000 receivers, we report detections of volcano-induced AGWs in mesopause and ionosphere-thermosphere airglow imagery and Fabry-Perot interferometry. We also report unique AGW signatures in the ionospheric D-region, measured …

Discourses Across Periods Of Time, Amanda Raquel Moreno

Theses

This literature review explores the revolutionary effect of generative artificial intelligence (AI) and virtual reality (VR) on digital art history, specifically concentrating on their capacity to enable dialogical exchanges with historical figures and deepen the understanding of artworks. This study considers the current state of research, detecting key methodologies, areas of improvement, and possible challenges and ethical concerns. The example historical figure used in this analysis is the iconic Mexican artist Frida Kahlo. Kahlo’s refusal to correspond to a specific artistic style makes her an ideal subject for generative AI and VR-based investigation, offering fresh insights into her work. The …

Detection Of Dsrab Operon Expression In Desulfotalea Psychrophila Cells Subjected To Simulated Martian Conditions Of Temperature And Regolith's Sulphate Minerals Composition, Sergio Mosquera, Mack Ivey, Vincent F. Chevrier

Biological Sciences Faculty Publications and Presentations

Discoveries of transient liquid water in the Martian polar caps and the presence of liquid lakes and subsurface oceans in icy satellites have increased the interest of scientists in the capabilities of terrestrial extremophiles to grow and remain metabolically active in these extreme environments. The principal goal of this research is to understand the metabolic capacity of the anaerobic psychrophile, Desulfotalea psychrophila, cultured at subfreezing temperatures in media containing various concentrations of sulphate minerals. In this regard, our experiments focused on the detection of D. psychrophila survival and active metabolism, employing a biochamber that can recreate Martian temperatures. Using …

Responsibility Gaps And Black Box Healthcare Ai: Shared Responsibilization As A Solution, Benjamin H Lang, Sven Nyholm, Jennifer Blumenthal-Barby

Center for Medical Ethics and Health Policy Staff Publications

As sophisticated artificial intelligence software becomes more ubiquitously and more intimately integrated within domains of traditionally human endeavor, many are raising questions over how responsibility (be it moral, legal, or causal) can be understood for an AI’s actions or influence on an outcome. So called “responsibility gaps” occur whenever there exists an apparent chasm in the ordinary attribution of moral blame or responsibility when an AI automates physical or cognitive labor otherwise performed by human beings and commits an error. Healthcare administration is an industry ripe for responsibility gaps produced by these kinds of AI. The moral stakes of healthcare …

Selecting Patient-Reported Outcome Measures For A Patient-Facing Technology

Faculty, Staff and Student Publications

OBJECTIVE: This article provides insight into our process and considerations for selecting patient-reported outcome measures (PROMs) designed for self-reporting symptoms and quality-of-life among breast cancer (BCA) patients undergoing oral anticancer agent treatment via a patient-facing technology (PFT) platform.

METHODS: Following established guidelines, we conducted a thorough assessment of a specific set of PROMs, comparing their content to identify the most suitable options for studying BCA patients.

RESULTS: We recommend utilizing the combination of EORTC QLQ-C30 + EORTC QLQ-BR45 as the preferred instrument, especially when developing a dedicated "breast cancer-only" application.

DISCUSSION: When developing and maintaining a dashboard for a PFT …

Virtual Reality In Simulation-Based Emergency Skills Training: A Systematic Review With A Narrative Synthesis, Antony Payton, Brendan Mcgrath, Neil Tolley, Iain Bruce

Faculty, Staff and Student Publications

OBJECTIVE: An important role is predicted for virtual reality (VR) in the future of medical education. We performed a systematic review of the literature with a narrative synthesis, to examine the current evidence for VR in simulation-based emergency skills training. We broadly define emergency skills as any clinical skill used in the emergency care of patients across all clinical settings.

METHODS: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines. The data sources accessed during this study included: PubMed, CINAHL, EMBASE, AMED, EMCARE, HMIC, BNI, PsychINFO, Medline, CENTRAL, SCOPUS, Web of Science, BIOSIS …

A Transcriptomic Taxonomy Of Mouse Brain-Wide Spinal Projecting Neurons, Cindy T J Van Velthoven, Zizhen Yao, Changkyu Lee, Zicong Zhang, Shuguang Yu, Kun Gao, Geraldine Duque Salazar, Evgenii Kegeles, Yu Zhang, Makenzie C Tomihiro, Yiming Zhang, Zhiyun Yang, Junjie Zhu, Jing Tang, Xuan Song, Ryan J Donahue, Qing Wang, Delissa Mcmillen, Michael Kunst, Ning Wang, Kimberly A Smith, Gabriel E Romero, Michelle M Frank, Alexandra Krol, Riki Kawaguchi, Daniel H Geschwind, Guoping Feng, Lisa V Goodrich, Yuanyuan Liu, Bosiljka Tasic, Hongkui Zeng, Zhigang He

Faculty, Staff and Student Publications

The brain controls nearly all bodily functions via spinal projecting neurons (SPNs) that carry command signals from the brain to the spinal cord. However, a comprehensive molecular characterization of brain-wide SPNs is still lacking. Here we transcriptionally profiled a total of 65,002 SPNs, identified 76 region-specific SPN types, and mapped these types into a companion atlas of the whole mouse brain1. This taxonomy reveals a three-component organization of SPNs: (1) molecularly homogeneous excitatory SPNs from the cortex, red nucleus and cerebellum with somatotopic spinal terminations suitable for point-to-point communication; (2) heterogeneous populations in the reticular formation with broad …

Single-Cell Analysis Of Chromatin Accessibility In The Adult Mouse Brain, Sainath Mamde, Maria Luisa Amaral, Yuelai Wang, Andre Chu, Yang Xie, Michael Miller, Jie Xu, Zhaoning Wang, Kai Zhang, Bojing Jia, Xiaomeng Hou, Lin Lin, Qian Yang, Seoyeon Lee, Bin Li, Samantha Kuan, Hanqing Liu, Jingtian Zhou, Antonio Pinto-Duarte, Jacinta Lucero, Julia Osteen, Michael Nunn, Kimberly A Smith, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Zihan Wang, Jingbo Shang, M Margarita Behrens, Joseph R Ecker, Allen Wang, Sebastian Preissl, Bing Ren

Faculty, Staff and Student Publications

Recent advances in single-cell technologies have led to the discovery of thousands of brain cell types; however, our understanding of the gene regulatory programs in these cell types is far from complete1-4. Here we report a comprehensive atlas of candidate cis-regulatory DNA elements (cCREs) in the adult mouse brain, generated by analysing chromatin accessibility in 2.3 million individual brain cells from 117 anatomical dissections. The atlas includes approximately 1 million cCREs and their chromatin accessibility across 1,482 distinct brain cell populations, adding over 446,000 cCREs to the most recent such annotation in the mouse genome. The mouse brain cCREs are …

Brain-Wide Correspondence Of Neuronal Epigenomics And Distant Projections, Yan Pang, Anna Bartlett, Zihao Peng, Wubin Ding, Angeline Rivkin, Will N Lagos, Elora Williams, Cheng-Ta Lee, Paula Assakura Miyazaki, Andrew Aldridge, Qiurui Zeng, J L Angelo Salinda, Naomi Claffey, Michelle Liem, Conor Fitzpatrick, Lara Boggeman, Zizhen Yao, Kimberly A Smith, Bosiljka Tasic, Jordan Altshul, Mia A Kenworthy, Cynthia Valadon, Joseph R Nery, Rosa G Castanon, Neelakshi S Patne, Minh Vu, Mohammad Rashid, Matthew Jacobs, Tony Ito, Julia Osteen, Nora Emerson, Jasper Lee, Silvia Cho, Jon Rink, Hsiang-Hsuan Huang, António Pinto-Duartec, Bertha Dominguez, Jared B Smith, Carolyn O'Connor, Hongkui Zeng, Shengbo Chen, Kuo-Fen Lee, Eran A Mukamel, Xin Jin, M Margarita Behrens, Joseph R Ecker, Edward M Callaway

Faculty, Staff and Student Publications

Single-cell analyses parse the brain’s billions of neurons into thousands of ‘cell-type’ clusters residing in different brain structures1. Many cell types mediate their functions through targeted long-distance projections allowing interactions between specific cell types. Here we used epi-retro-seq2 to link single-cell epigenomes and cell types to long-distance projections for 33,034 neurons dissected from 32 different regions projecting to 24 different targets (225 source-to-target combinations) across the whole mouse brain. We highlight uses of these data for interrogating principles relating projection types to transcriptomics and epigenomics, and for addressing hypotheses about cell types and connections related to genetics. …

Fimap A Fast Identity-By-Descent Mapping Test For Biobank-Scale Cohorts

Faculty, Staff and Student Publications

Although genome-wide association studies (GWAS) have identified tens of thousands of genetic loci, the genetic architecture is still not fully understood for many complex traits. Most GWAS and sequencing association studies have focused on single nucleotide polymorphisms or copy number variations, including common and rare genetic variants. However, phased haplotype information is often ignored in GWAS or variant set tests for rare variants. Here we leverage the identity-by-descent (IBD) segments inferred from a random projection-based IBD detection algorithm in the mapping of genetic associations with complex traits, to develop a computationally efficient statistical test for IBD mapping in biobank-scale cohorts. …

Molecularly Defined And Spatially Resolved Cell Atlas Of The Whole Mouse Brain, Stephen W Eichhorn, Zhiyun Lei, Limor Cohen, Kimberly A Smith, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Xiaowei Zhuang

Faculty, Staff and Student Publications

In mammalian brains, millions to billions of cells form complex interaction networks to enable a wide range of functions. The enormous diversity and intricate organization of cells have impeded our understanding of the molecular and cellular basis of brain function. Recent advances in spatially resolved single-cell transcriptomics have enabled systematic mapping of the spatial organization of molecularly defined cell types in complex tissues1-3, including several brain regions (for example, refs. 1-11). However, a comprehensive cell atlas of the whole brain is still missing. Here we imaged a panel of more than 1,100 genes in approximately 10 million cells across the …

Single-Cell Dna Methylome And 3d Multi-Omic Atlas Of The Adult Mouse Brain, Bang-An Wang, Peter Berube, Wei Tian, Mia Kenworthy, Jordan Altshul, Joseph R Nery, Huaming Chen, Rosa G Castanon, Songpeng Zu, Yang Eric Li, Jacinta Lucero, Julia K Osteen, Antonio Pinto-Duarte, Jasper Lee, Jon Rink, Silvia Cho, Nora Emerson, Michael Nunn, Carolyn O'Connor, Zhanghao Wu, Ion Stoica, Zizhen Yao, Kimberly A Smith, Bosiljka Tasic, Chongyuan Luo, Jesse R Dixon, Hongkui Zeng, Bing Ren, M Margarita Behrens, Joseph R Ecker

Faculty, Staff and Student Publications

Cytosine DNA methylation is essential in brain development and is implicated in various neurological disorders. Understanding DNA methylation diversity across the entire brain in a spatial context is fundamental for a complete molecular atlas of brain cell types and their gene regulatory landscapes. Here we used single-nucleus methylome sequencing (snmC-seq3) and multi-omic sequencing (snm3C-seq)1 technologies to generate 301,626 methylomes and 176,003 chromatin conformation–methylome joint profiles from 117 dissected regions throughout the adult mouse brain. Using iterative clustering and integrating with companion whole-brain transcriptome and chromatin accessibility datasets, we constructed a methylation-based cell taxonomy with 4,673 cell groups and 274 …

Targeted Gene Expression Profiling Predicts Meningioma Outcomes And Radiotherapy Responses, Calixto-Hope G Lucas, Kanish Mirchia, Sybren L N Maas, Abigail K Suwala, Minhee Won, James C Bayley, Akdes S Harmanci, Arif O Harmanci, Tiemo J Klisch, Minh P Nguyen, Harish N Vasudevan, Kathleen Mccortney, Theresa J Yu, Varun Bhave, Tai-Chung Lam, Jenny Kan-Suen Pu, Lai-Fung Li, Gilberto Ka-Kit Leung, Jason W Chan, Haley K Perlow, Joshua D Palmer, Christine Haberler, Anna S Berghoff, Matthias Preusser, Theodore P Nicolaides, Christian Mawrin, Sameer Agnihotri, Adam Resnick, Brian R Rood, Jessica Chew, Jacob S Young, Lauren Boreta, Steve E Braunstein, Jessica Schulte, Nicholas Butowski, Sandro Santagata, David Spetzler, Nancy Ann Oberheim Bush, Javier E Villanueva-Meyer, James P Chandler, David A Solomon, C Leland Rogers, Stephanie L Pugh, Minesh P Mehta, Penny K Sneed, Mitchel S Berger, Craig M Horbinski, Michael W Mcdermott, Arie Perry, Wenya Linda Bi, Akash J Patel, Felix Sahm, Stephen T Magill, David R Raleigh

Faculty, Staff and Student Publications

Surgery is the mainstay of treatment for meningioma, the most common primary intracranial tumor, but improvements in meningioma risk stratification are needed and indications for postoperative radiotherapy are controversial. Here we develop a targeted gene expression biomarker that predicts meningioma outcomes and radiotherapy responses. Using a discovery cohort of 173 meningiomas, we developed a 34-gene expression risk score and performed clinical and analytical validation of this biomarker on independent meningiomas from 12 institutions across 3 continents (N = 1,856), including 103 meningiomas from a prospective clinical trial. The gene expression biomarker improved discrimination of outcomes compared with all other systems …

Inundated Vegetation Response To Ongoing Restoration And Its Impacts On Fish Community Structure, Emmanuel J. May

All Graduate Theses and Dissertations, Fall 2023 to Present

Shallow lake ecosystems and their associated wetland habitats globally are subject to non-native species introductions, nutrient loading, and water level fluctuations, each of which can decrease vegetated habitat availability, exposing vulnerable native aquatic species to predation. Managers are frequently tasked with mitigating native species declines by restoring vegetation considered crucial for their survival. However, restoring vegetation can be challenging in the presence of multiple stressors, requiring managers to assess the relative importance of the different stressors limiting vegetation recovery.

Utah Lake is a large shallow lake subject to multiple stressors and has shifted from a mesotrophic lake with abundant aquatic …

Constraining Silicate Weathering During The Middle Eocene Climatic Optimum (Meco) Using Radiolarian Ge/Si, Olivia R. Laub

All Graduate Theses and Dissertations, Fall 2023 to Present

Silicate weathering has long been considered a fundamental component of the earth system and has been cited as one of, if not the primary stabilizing feedback for climate. However, recent work has shown that the role of silicate weathering in the climate system is more complicated and dynamic than previously assumed. In this study I examine the role of weathering in the enigmatic warming event, the Middle Eocene Climatic Optimum (MECO) that occurred approximately 40 Ma. This event works as a good case study as there are multiple features of the MECO that differentiate it from other warming events that …

An Ensemble Approach For Mapping Snow Water Equivalent In Utah, Logan Schneider

All Graduate Theses and Dissertations, Fall 2023 to Present

Mountain snowpack is an important resource for water management planning in Utah. Snow water equivalent (SWE) is the amount of water contained in a snowpack. A few organizations predict SWE throughout the United States but struggle making accurate predictions in mountainous regions. Weather stations provide accurate measurements of SWE but have limited spatial coverage that hinders the ability to make accurate estimates statewide. This thesis examines the accuracy of current models and proposes using local weather measurements to improve upon national level predictions. An R statistical software package named rsnodas implements this process while allowing the public access to a …

Transferability Of Tsetse Habitat Models Between Different Regions In Kenya And Rwanda, Stella Gachoki, Anton Vrieling, Thomas A. Groen, Andrew Skidmore, Daniel Masiga

All Peer-Reviewed Publications

Accurate and reliable information on the distribution of tsetse habitats is crucial for the effective management of African Trypanosomiasis in sub-Saharan Africa. However, conducting large-scale surveillance of tsetse flies to develop distribution maps is impractical due to vast areas infested and limited resources available. To address this challenge, we evaluated the applicability of tsetse habitat models developed in the intensively sampled Shimba Hills National Reserve in Kenya for both the wet and the dry season, to two other regions in Kenya (Ruma National Park and Nguruman Conservancy) and one region in Rwanda (Akagera National Park). The models utilized satellite-based estimates …

Regioselective Catalytic Synthesis Of Potentially Bioactive 1,3,4-Selenadiazole, Mohamed Ali Mahmoud

Theses

Isoselenocyanates have a crucial role as reactants in chemical processes, facilitating the efficient synthesis of significant chemical intermediates and physiologically active chemicals. The utilization of (Z)-2-oxo-N-phenylpropanehydrazonoyl chlorides in a one-step procedure for the synthesis of the core structure of various heterocyclic compounds has been widely explored. This study focuses on the synthesis of 5-arylimino-1,3,4-selenadiazole derivatives through the reaction of isoselenocyanates with various substituted (Z)-2-oxo-N-phenylpropanehydrazonoyl chlorides. The objective is to achieve selective and accurate formation of these derivatives. The derivatives exhibit a diverse range of functional groups on both aryl rings. The synthetic procedure is conducted under ambient conditions, promoting environmental …

Assessing Open Source Tools For Enhanced Forensic Analysis Of Unmanned Aerial Vehicles (Uavs), Nura Shifa Hamed

Theses

The widespread applications of Unmanned Aerial Vehicles (UAVs), commonly referred to as drones, has given rise to significant national security threats due to their illicit activities. Consequently, the domain of UAV forensics is rapidly evolving, presenting a substantial knowledge deficit among forensic experts. Open source tools provide accessible and affordable resources, making it easier for investigators to bridge this gap by gaining expertise in the use of these tools. This helps ensure that forensic professionals can keep up with the ever-changing UAV technology landscape. This thesis undertakes the mission of navigate the complex field of drone forensics and conducting a …

Analysis Of Pharmaceutical Residues In Wastewater From Al Ain, United Arab Emirates Using Liquid Chromatography - Tandem Mass Spectrometry And Circular Dichroism: Potential Hazardous Emergent Contaminants, Maya Iyad Berakdar

Theses

Although water is the second essential substance to life after air, clean water resources in many regions of the world have become limited because of climate change, establishing rivers’ dams and contaminations with hazardous life-threatening chemicals. Pharmaceutical residues in aquatic environments have been recognized as emerging contaminants causing adverse ecological and human health risks. Hundreds of pharmaceutical compounds and their metabolites were found in surface, underground, drinking, and sewage waters in many countries. In the United Arab Emirates, millions of drugs’ dosages are annually used for human, poultry, and veterinary treatments. Drugs execrated as unchanged, metabolites or excesses can find …

A Comprehensive Assessment Of Anthropogenic And Natural Sources And Sinks Of Australasia's Carbon Budget, Yohanna Villalobos, Josep G. Canadell, Elizabeth D. Keller, Peter R. Briggs, Beata Bukosa, Donna L. Giltrap, Ian Harman, Timothy W. Hilton, Miko U. F. Kirschbaum, Ronny Lauerwald, Liyin L. Liang, Taylor Maavara, Sara E. Mikaloff-Fletcher, Peter J. Rayner, Laure Resplandy, Judith Rosentreter, Eva M. Metz, Oscar Serrano, Benjamin Smith

Research outputs 2022 to 2026

Regional carbon budget assessments attribute and track changes in carbon sources and sinks and support the development and monitoring the efficacy of climate policies. We present a comprehensive assessment of the natural and anthropogenic carbon (C-CO2) fluxes for Australasia as a whole, as well as for Australia and New Zealand individually, for the period from 2010 to 2019, using two approaches: bottom-up methods that integrate flux estimates from land-surface models, data-driven models, and inventory estimates; and top-down atmospheric inversions based on satellite and in situ measurements. Our bottom-up decadal assessment suggests that Australasia's net carbon balance was close to carbon …

Globally-Distributed Microbial Eukaryotes Exhibit Endemism At Deep-Sea Hydrothermal Vents, Sarah K. Hu, Amy R. Smith, Rika E. Anderson, Sean P. Sylva, Michael Setzer, Maria Steadmon, Kiana L. Frank, Eric W. Chan, Darlene S. S. Lim, John A. Breier

School of Earth, Environmental, & Marine Sciences Faculty Publications

Single-celled microbial eukaryotes inhabit deep-sea hydrothermal vent environments and play critical ecological roles in the vent-associated microbial food web. 18S rRNA amplicon sequencing of diffuse venting fluids from four geographically- and geochemically-distinct hydrothermal vent fields was applied to investigate community diversity patterns among protistan assemblages. The four vent fields include Axial Seamount at the Juan de Fuca Ridge, Sea Cliff and Apollo at the Gorda Ridge, all in the NE Pacific Ocean, and Piccard and Von Damm at the Mid-Cayman Rise in the Caribbean Sea. We describe species diversity patterns with respect to hydrothermal vent field and sample type, identify …

New Paths Of Attacks: Revealing The Adaptive Integration Of Artificial Intelligence In Evolving Cyber Threats Targeting Social Media Users And Their Data, Larry Teasley

Cybersecurity Undergraduate Research Showcase

The intersection between artificial intelligence tools and social media has opened doors to numerous opportunities and risks. This research delves into the escalating threat landscape in a society heavily dependent on social media. Despite the efforts by social media companies and cybersecurity professionals to mitigate cyber-attacks, the constant advancements of new technologies render social media platforms increasingly vulnerable. Malicious actors exploit generative AI to collect user data, enhancing cyber threats on social media. Notably, generative AI amplifies phishing attacks, disseminates false information, and propagates propaganda, posing substantial challenges to platform security. Ease access to large language models (LLMs) further complicates …

A Review Of Threat Vectors To Dna Sequencing Pipelines, Tyler Rector

Cybersecurity Undergraduate Research Showcase

Bioinformatics is a steadily growing field that focuses on the intersection of biology with computer science. Tools and techniques developed within this field are quickly becoming fixtures in genomics, forensics, epidemiology, and bioengineering. The development and analysis of DNA sequencing and synthesis have enabled this significant rise in demand for bioinformatic tools. Notwithstanding, these bioinformatic tools have developed in a research context free of significant cybersecurity threats. With the significant growth of the field and the commercialization of genetic information, this is no longer the case. This paper examines the bioinformatic landscape through reviewing the biological and cybersecurity threats within …