Physical Sciences and Mathematics Commons^™

Longitudinal Thermal And Solute Dynamics In Regulated Rivers, Muhammad Rezaul Haider

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Dam releases increase river stage and can reverse groundwater movement into and out of the river. As the flood, thermal, and solute waves travel downstream in a regulated river, the size of the waves is anticipated to be affected both by river processes and exchanges with near river groundwater. This study established a modeling framework to quantify the influences of the groundwater exchanges on the temperatures and solute concentration dynamics along regulated rivers. The wave properties, volume of exchanges, conservative solute mass exchanges, and heat energy exchanges were calculated as a function of time and distance downstream. Results show that …

Bioinformatic And Biophysical Analyses Of Proteins, Jonathan Catazaro

Department of Chemistry: Dissertations, Theses, and Student Research

The prevailing dogma in structural genomics is the existence of a strong correlation between protein sequence, structure, and biological function. Proteins with high sequence similarity typically have a similar, if not the same, structure and function. In many cases this logic can fail due to distantly related proteins having very low sequence similarity, a lack of a representative structure, structural novelty, or the absence of a characterized function. Further, the paradigm fails to account for dynamics, which have a significant effect on structural stability and enzymatic efficacy.

Nuclear magnetic resonance (NMR) spectroscopy is uniquely capable of solving the structure, assisting …

Urban Foraging: A Ubiquitous Human Practice Overlooked By Urban Planners, Policy, And Research, Charlie M. Shackleton, Patrick T. Hurley, Annika C. Dahlberg, Marla R. Emery, Harini Nagendra

Environment and Sustainability Faculty Publications

Although hardly noticed or formally recognized, urban foraging by humans probably occurs in all urban settings around the world. We draw from research in India, South Africa, Sweden, and the United States to demonstrate the ubiquity and varied nature of urban foraging in different contexts. Across these different contexts, we distill seven themes that characterize and thereby advance thinking about research and the understanding of urban foraging. We show that it is widespread and occurs across a variety of urban spaces and places. The species used and the local practices vary between contexts, and are in constant flux as urban …

Sma Observations Of The Hot Molecular Core Iras 18566+0408, Andrea Silva, Qizhou Zhang, Patricio Sanhueza, Xing Lu, Maria T. Beltran, Cassandra Fallscheer, Henrik Beuther, T. K. Sridharan, Riccardo Cesaroni

All Faculty Scholarship for the College of the Sciences

We present Submillimeter Array (SMA) observations toward the high-mass star-forming region IRAS 18566+0408. Observations at the 1.3 mm continuum and in several molecular line transitions were performed in the compact (2ʺ4 angular resolution) and very-extended (~0ʺ4 angular resolution) configurations. The continuum emission from the compact configuration shows a dust core of 150 M _⊙, while the very-extended configuration reveals a dense (2.6 × 10⁷ cm⁻³) and compact (~4000 au) condensation of 8 M _⊙. We detect 31 molecular transitions from 14 species including CO isotopologues, SO, CH₃OH, OCS, and CH₃CN. Using …

Microstructure Of Injection Moulding Machine Mould Clamping Mechanism: Design And Motion Simulation, Z. Jin, Y. Zhang, X. Wang, J. Williams, Z. Liu, Z. Huang, D. Falkner, G. Zhou, L. Dong, J. Zhuang, Zhe Wang

Faculty and Staff Publications

With the advent of intelligence technologies, more and more machines and devices are involved in the creation of complex structures. In the intelligent manufacturing industries, mouldings including injection moulding, blow moulding, compression moulding, and others play critical roles in manufacturing highly precise parts required for building intelligent machines (such as computers, cell phones, robots etc.). The performance of the clamping mechanism directly affects the quality of the microstructure of injection products. The design of the injection moulding mould clamping mechanism is based on the microstructure characteristics of the trip of the toggle lever mechanism ratio, speed ratio, and force amplification …

Review Of Ligand Specificity Factors For Cyp1a Subfamily Enzymes From Molecular Modeling Studies Reported To-Date, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu, Maryam Foroozesh

Faculty and Staff Publications

The cytochrome P450 (CYP) family 1A enzymes, CYP1A1 and CYP1A2, are two of the most important enzymes implicated in the metabolism of endogenous and exogenous compounds through oxidation. These enzymes are also known to metabolize environmental procarcinogens into carcinogenic species, leading to the advent of several types of cancer. The development of selective inhibitors for these P450 enzymes, mitigating procarcinogenic oxidative effects, has been the focus of many studies in recent years. CYP1A1 is mainly found in extrahepatic tissues while CYP1A2 is the major CYP enzyme in human liver. Many molecules have been found to be metabolized by both of …

Robustness Of Observation-Based Decadal Sea Level Variability In The Indo-Pacific Ocean, A. G. Nidheesh, M. Lengaigne, J. Vialard, T. Izumo, A. S. Unnikrishnan, B. Meyssignac, B. Hamlington, C. De Boyer Montegut

OES Faculty Publications

We examine the consistency of Indo-Pacific decadal sea level variability in 10 gridded, observation-based sea level products for the 1960-2010 period. Decadal sea level variations are robust in the Pacific, with more than 50% of variance explained by decadal modulation of two flavors of El Nino-Southern Oscillation (classical ENSO and Modoki). Amplitude of decadal sea level variability is weaker in the Indian Ocean than in the Pacific. All data sets indicate a transmission of decadal sea level signals from the western Pacific to the northwest Australian coast through the Indonesian throughflow. The southern tropical Indian Ocean sea level variability is …

Eulerian On Lagrangian Cloth Simulation, Kyle C. Piddington

Master's Theses

This thesis introduces a novel Eulerian-on-Lagrangian (EoL) approach for simulating cloth. This approach allows for the simulation of traditionally difficult cloth scenarios, such as draping and sliding cloth over sharp features like the edge of a table. A traditional Lagrangian approach models a cloth as a series of connected nodes. These nodes are free to move in 3d space, but have difficulty with sliding over hard edges. The cloth cannot always bend smoothly around these edges, as motion can only occur at existing nodes. An EoL approach adds additional flexibility to a Lagrangian approach by constructing special Eulerian on Lagrangian …

Dynamics Of Gene Networks In Cancer Research, Paul Scott

Electronic Theses and Dissertations

Cancer prevention treatments are being researched to see if an optimized treatment schedule would decrease the likelihood of a person being diagnosed with cancer. To do this we are looking at genes involved in the cell cycle and how they interact with one another. Through each gene expression during the life of a normal cell we get an understanding of the gene interactions and test these against those of a cancerous cell. First we construct a simplified network model of the normal gene network. Once we have this model we translate it into a transition matrix and force changes on …

Population Dynamics Of A Recently Described And Rare Plant Species: Stachys Caroliniana (Lamiaceae), Shelby Moody

Theses and Dissertations

Stachys caroliniana J.B. Nelson & D.A. Rayner, a newly described ‘hedge-nettle’ is found in two locations in South Carolina. The first known collection of this species is from the Santee Coastal Reserve in Charleston County. The second location (the type locality) is from the Tom Yawkey Wildlife Center in Georgetown County, approximately 8 air miles northeast of the first location. This study focused on the population in Georgetown County. Population dynamics of Stachys caroliniana were studied in order to provide management guidelines to South Carolina Department of Natural Resources for this species. This was achieved by assessing suitable habitat conditions, …

Effects Of Sea Level Rise On Hydrology: Case Study In A Typical Mid-Atlantic Coastal Watershed, Xixi Wang, Rui Li, Homa Jalaeian Taghadomi, Shohreh Pedram, Xiao Zhao

Civil & Environmental Engineering Faculty Publications

Sea level rise (SLR) can negatively affect the hydrology of coastal watersheds. However, the relevant information is incomplete and insufficient in existing literature. The objective of this study is to present a modeling approach to predict long-term effects of SLR on changes of flood peak, flood stage, and groundwater table with an assumption that the historical climate would reoccur in the future. The study was conducted for a typical coastal watershed in southeast USA. The results indicate that sea level had been rising at a rate of 4.21 mm yr⁻¹ from 1948 to 1982 but at a faster rate …