Physical Sciences and Mathematics Commons^™

The Cosm Newsletter

The COSM Newsletter (2008-2018)

• Eagles in Training for STEM Careers
• The Department of Biology Welcomes New Faculty
• Biology Alumni Move Onward and Upward
• Georgia Southern's Elite 8 for REU-2016
• Geologists Investigate Salt Water Intrusion on a Georgia Barrier Island
• The Georgia Southern Sea Turtle Program at St. Catherines Island: The 2016 Sea Turtle Nesting Season
• Hatchlings
• The Department of Mathematical Sciences Welcomes New Faculty
• Eagles Win Third MacArthur Award
• Faculty member awarded new Patent on “Engineered lumenized vascular networks and support matrix”
• The Photonic Nanotechnology Computational Group
• Edwards participates in NSF "Ideas Lab" to Measure "Big G"
• Faculty Member Participates in Scholarly Activities
• Professors …

Cosm News, Georgia Southern University

College of Science and Mathematics News (2012-2019)

• Biology Professor Receives Grant

The Function Of Renalase, Brett Allen Beaupre

Theses and Dissertations

Renalase was originally reported to be an enzyme secreted into the blood by the kidney to lower blood pressure and slow heart rate. Despite multiple reports claiming to confirm this activity in vivo there has been considerable discord in regards to the reaction catalyzed by renalase. The structural topology of renalase resembles that of known flavoprotein oxidases, monooxygenases and demethylases, but the conserved active site residues are unique to renalase. It has been reported that the catalytic function of renalase is to oxidize circulating catecholamines, however in vitro studies have failed to demonstrate a catalytic activity in the presence of …

Injury Severity Data For Front And Second Row Passengers In Frontal Crashes, Theresa Atkinson, Leszek Gawarecki, Massoud S. Tavakoli

Mathematics Publications

The data contained here were obtained from the National Highway Transportation Safety Administration׳s National Automotive Sampling System – Crashworthiness Data System (NASS-CDS) for the years 2008–2014. This publically available data set monitors motor vehicle crashes in the United States, using a stratified random sample frame, resulting in information on approximately 5000 crashes each year that can be utilized to create national estimates for crashes. The NASS-CDS data sets document vehicle, crash, and occupant factors. These data can be utilized to examine public health, law enforcement, roadway planning, and vehicle design issues. The data provided in this brief are a subset …

2016-01-A3dsrinp-Csc-Sta-Cmb-522-Bps-542, Raymond Pulver, Neal Buxton, Xiaodong Wang, John Lucci, Jean Yves Hervé, Lenore Martin

Bioinformatics Software Design Projects

Cholesterol is carried and transported through bloodstream by lipoproteins. There are two types of lipoproteins: low density lipoprotein, or LDL, and high density lipoprotein, or HDL. LDL cholesterol is considered “bad” cholesterol because it can form plaque and hard deposit leading to arteries clog and make them less flexible. Heart attack or stroke will happen if the hard deposit blocks a narrowed artery. HDL cholesterol helps to remove LDL from the artery back to the liver.

Traditionally, particle counts of LDL and HDL plays an important role to understanding and prediction of heart disease risk. But recently research suggested that …

Spontaneous Calcium Release In Cardiac Myocytes: Store Overload And Electrical Dynamics, Amanda M. Alexander, Erin K. Denardo, Eric Frazier Iii, Michael Mccauley, Nicholas Rojina, Zana Coulibaly, Bradford E. Peercy, Leighton T. Izu

Spora: A Journal of Biomathematics

Heart disease is the leading cause of mortality in the United States. One cause of heart arrhythmia is calcium (Ca²⁺) mishandling in cardiac muscle cells. We adapt Izu's et al. mathematical reaction-diffusion model of calcium in cardiac muscle cells, or cardiomyocytes implemented by Gobbert, and analyzed in Coulibaly et al. to include calcium being released from the sarcoplasmic reticulum (SR), the effects of buffers in the SR, particularly calsequestrin, and the effects of Ca²⁺ influx due to voltage across the cell membrane. Based on simulations of the model implemented in parallel using MPI, our findings aligned with …

The Cosm Newsletter

The COSM Newsletter (2008-2018)

• Research Cooperative Membership Approved
• Bo Ginn National Fish Hatchery
• Faculty Highlights
• Professor Heralds Unsung Pioneer of Evolutionary Biology in LeConte Lecture
• Biology Students Recognized
• Special Thank You to Dr. Daniel Hagan and Miriam Hagan
• Mole Day & National Chemistry Week Celebration 2015
• Mole Day & National Chemistry Week Celebration 2015
• Chemistry Student Presents at Annual Biomedical Research Conference
• Dr. Anke Hildebrandt Talk
• 28th Annual Mathematics Tournament
• Eagle Battalion to Build New $9.5 Million Building
• Dr. Maxim Durach's Nanotechnology Computational Group
• Dr. Xiaojun Wang Research in Phosphors
• Dr. Monique Aller Presents Interstellar Matter Research at the International Astronomical Union
• Physics Team …

Spring 2016

Scientia

Stress busters: intervention study combats stress in African-American youth; Peer-to-peer health power; Research roundup; Notes from the field; Program accelerates health care careers; Deep dive: Alumnus researches underwater volcanoes; Lab notes

Derting Et Al 2016 Science Advances 2016 Full.Pdf, Terry Derting

Terry Derting

Uno Website Biology Uno Nature Preserves, Uno Department Of Biology

Student Support

Glacier Creek Preserve and T.L. Davis Preserve are managed by the Department of Biology to restore and preserve some of eastern Nebraska's natural prairie and woodland heritage. These preserves serve as education and research sites for the region as well as sites for those interested in enjoying the feel of our natural heritage.

The Role Of Rnase L In Type I Diabetes And Development Of Quantitative Lc-Ms/Ms Methods For The Pharmacological Studies Of Anti-Cancer Drug Candidates, Chun Zeng

ETD Archive

PROJECT I: The cause of type I diabetes continues to be a focus of investigation. In this study, we found that 2-5A dependent RNase L (RNase L), an IFN-a-inducible enzyme that functions in IFN action against viruses and cell proliferation, played an important role in dsRNA-induced onset of type I diabetes. By using RNase L deficient RIP-B7.1 mice which are more vulnerable to environmental harmful factors such as viral infection, we demonstrated that deficiency of RNase L in mice resulted in a significant delay of diabetes onset induced by polyinosinic:polycytidylic acid (poly I:C), a type of dsRNA, and streptozotocin (STZ). …

Selective Mutation Accumulation: A Computational Model Of The Paternal Age Effect, Eoin C. Whelan, Alexander C. Nwala, Christopher Osgood, Stephan Olariu

Biological Sciences Faculty Publications

Motivation: As the mean age of parenthood grows, the effect of parental age on genetic disease and child health becomes ever more important. A number of autosomal dominant disorders show a dramatic paternal age effect due to selfish mutations: substitutions that grant spermatogonial stem cells (SSCs) a selective advantage in the testes of the father, but have a deleterious effect in offspring. In this paper we present a computational technique to model the SSC niche in order to examine the phenomenon and draw conclusions across different genes and disorders.

Results: We used a Markov chain to model the probabilities of …

Mechanisms Of Antixenosis And Antibiosis Of Ash Against Emerald Ash Borer, Chad Michael Rigsby

Browse all Theses and Dissertations

Emerald ash borer (EAB), Agrilus planipennis (Coleoptera: Buprestidae), is an invasive forest pest causing widespread mortality of ash (Fraxinus spp.) in North America. Host resistance research and the development of resistant hosts offers a promising strategy for the long-term conservation of ash and management of EAB. Manchurian ash (F. mandshurica) shares an evolutionary history with EAB in Asia, resulting in its greater resistance relative to naive North American ashes. In the following studies I investigate antixenosis and antibiosis mechanisms of resistant and susceptible ashes. Antixenosis in Manchurian ash was demonstrated by quantifying substantially lower oviposition on this species relative to …