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The Periodical Fall 2016, Southern Adventist University Oct 2016

The Periodical Fall 2016, Southern Adventist University

the Periodical – Chemistry Department Newsletter

Volume 4, issue 1 of the Periodical includes articles about renovations to the Chemistry and Math departments, a chemistry professor conference, the high school forensic chemistry academic summer camp, an alumni spotlight, and a pictorial listing of December 2016 graduates.


Design And Implementation Of Asymptotically Optimal Mesh Slicing Algorithms Using Parallel Processing, Christopher Dant May 2016

Design And Implementation Of Asymptotically Optimal Mesh Slicing Algorithms Using Parallel Processing, Christopher Dant

MS in Computer Science Project Reports

Mesh slicing is the process of taking a three dimensional model and reducing it to 2.5 dimensional layers that together create a layered representation of the model. The process is used in layered additive manufacturing, three dimensional voxelization, and other similar problems in computational geometry. The slicing process is computationally expensive, and the time required to slice an object can inhibit the viability of layered manufacturing in some industries. We designed and developed a fast implementation of the slicing process, called Sunder, that uses new asymptotically optimal algorithms and takes advantage of parallel processing platforms. To our knowledge, no other …


Development Of A Surgical Instrument Prototype To Perform A More Precise Capsulorhexis, Kirk Haugen May 2016

Development Of A Surgical Instrument Prototype To Perform A More Precise Capsulorhexis, Kirk Haugen

Journal of Interdisciplinary Undergraduate Research

Performing capsulorhexis is often considered the most difficult part of cataract surgery. Not only is it difficult, but performing it correctly is important for refractive outcomes.4 Inaccurate capsulorhexes are associated with complications including posterior capsular opacification, capsular fibrosis, and capsular phimosis.6 This study investigates the possibility of a proposed surgical instrument producing more precise capsulorhexes as determined by the circularity index. 60 capsulorhexes were performed on cigarette paper laid over clay - half using the continuous curvilinear capsulorhexis (CCC) method, and half using the proposed instrument. The precision of the capsulorhexis was then measured using the circularity index. …


Innovative Synthesis Of Diltiazem/Clentiazem Analogs, Emelyn Magtanong May 2016

Innovative Synthesis Of Diltiazem/Clentiazem Analogs, Emelyn Magtanong

Journal of Interdisciplinary Undergraduate Research

Cardiovascular disease defines disorders of the heart and blood vessels, and is the number one cause of death in America. Diltiazem and clentiazem are common calcium channel blockers incorporated into drugs used to treat various cardiovascular diseases. Methods to synthesize 5-[2-(dimethylamino)ethyl]-8-hydroxy-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one, an analog of the core of diltiazem and clentiazem, using cost-efficient starting materials allows for affordable treatment and increased availability to affected individuals. N-(N,N-dimethylethanamine)-4-aminophenol can be oxidized to form a quineoneimine, which can be further reacted with 3-mercaptopropionic acid via Michael addition. Subsequent addition of a coupling reagent, N,N'-dicyclocarbodiimide (DCC),1 produces 5-[2-(dimethylamino)ethyl]-8-hydroxy-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one, analogous to the core …


Inhibiting Fatty Acid Synthase In Rapidly Dividing Cells: Synthesis Of 5-(Alkylthio)-1h-Benzo[D]Imidazole-2,6-Diones, Andy Hausted May 2016

Inhibiting Fatty Acid Synthase In Rapidly Dividing Cells: Synthesis Of 5-(Alkylthio)-1h-Benzo[D]Imidazole-2,6-Diones, Andy Hausted

Journal of Interdisciplinary Undergraduate Research

Prostate and breast cancer are the number one and number two cancer sites, respectively, for male and females within the United States.1 Increased levels of the enzyme fatty acid synthase have been found in rapidly dividing cancer cells. This enzyme is responsible for the de novo synthesis of fatty acids in human cells, which are essential to cell growth and survival. The goal then for this research is to synthesize and design a new synthesis of 5-(alkylthio)-1Hbenzo[ d]imidazole-2,6-diones intended to successfully inhibit fatty acid synthase (FASN) by binding allosterically to the thioesterase domain of FASN. Thus by selectively inhibiting FASN …


Artificially Intelligent Computer Assisted Language Learning System With Ai Student Component, Denee M. Mcclain Jan 2016

Artificially Intelligent Computer Assisted Language Learning System With Ai Student Component, Denee M. Mcclain

Senior Research Projects

Intelligent Computer Assisted Language Learning (ICALL) systems follow an accepted format, which utilizes an artificially intelligent tutor. The systems allow the user to input a sentence in the target language and the AI tutor analyzes the sentence and provides error correction. This approach can be expensive, impractical, and inflexible. Inflexibility can result in a lower quality of learning for the users of these systems. Here I present an alternative format for ICALL systems that utilizes an artificially intelligent student. This alternative is cost effective and practical because it does not require extra development time to make the artificial intelligence an …


The Periodical Winter 2016, Southern Adventist University Jan 2016

The Periodical Winter 2016, Southern Adventist University

the Periodical – Chemistry Department Newsletter

Volume 3, issue 2 of the Periodical includes articles about the Chemistry Club's community service, a pictorial listing of May 2016 graduates, student Jeron Estwick's presentation at a chemistry conference, a feature on students recognized for academic achievement, and an alumni spotlight.