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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

1985

Theses/Dissertations

Organic Chemistry

West Virginia University

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Full-Text Articles in Physical Sciences and Mathematics

Search For New Membrane Active Substances: Synthesis Of 3-Tropanols With Alkyl, Alkenyl And Alkenynyl Group At The Bridgehead, Ramalinga Murty Dharanipragada Jan 1985

Search For New Membrane Active Substances: Synthesis Of 3-Tropanols With Alkyl, Alkenyl And Alkenynyl Group At The Bridgehead, Ramalinga Murty Dharanipragada

Graduate Theses, Dissertations, and Problem Reports

In recent years, Witkop and coworkers have isolated several structurally unique alkaloids from the colombian frog belonging to the genera Dendrobates. These alkaloids, which occur in the defensive skin secretions of the frog have been found to be highly active venoms as well as mucosal tissue irritants towards both mammals and reptiles. Among them are three important alkaloids histrionicotoxin, isodihydrohistronicotoxin and octahydrohistronicotoxin.