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Full-Text Articles in Physical Sciences and Mathematics
Surface Water/Groundwater Interactions And Hydrogeochemical Characterization Of The Elkhorn Mine And Mill, Beaverhead County, Montana, Tyler Kamp
Graduate Theses & Non-Theses
The formation of acid mine drainage (AMD) and the contaminants associated with it have been described by some as the largest environmental problem facing the U.S. mining industry. Heavy metals associated with the drainage, such as copper, cadmium, and zinc affect the water quality of streams and can cause acute or chronic toxicity to invertebrates and fish (Martin, 1992& Padrillah et al., 2018). Elkhorn Creek in the Pioneer Mountains of southwest Montana is one of these impacted creeks. The historic Elkhorn Mine and Mill complex has historically attributed to the creek’s contamination and has undergone remediation. However, the problem has …
Improving Energy Efficiency Through Compiler Optimizations, Jack Beckitt-Marshall
Improving Energy Efficiency Through Compiler Optimizations, Jack Beckitt-Marshall
Honors Projects
Abstract--- Energy efficiency is becoming increasingly important for computation, especially in the context of the current climate crisis. The aim of this experiment was to see if the compiler could reduce energy usage without rewriting programs themselves. The experimental setup consisted of compiling programs using the Clang compiler using a set of compiler flags, and then measuring energy usage and execution time on an AMD Ryzen processor. Three experiments were performed: a random exploration of compiler flags, utilization of SIMD, as well as benchmarking real world applications. It was found that the compiler was able to reduce execution time, especially …
Benzene-1,3-Diamidoethanethiol (Bdeth2) And Its Metal Compounds, Kamruz Md Zaman
Benzene-1,3-Diamidoethanethiol (Bdeth2) And Its Metal Compounds, Kamruz Md Zaman
University of Kentucky Doctoral Dissertations
There is a global need to find a permanent and readily implemented solution to the problem of heavy metal pollution in aqueous environments. A dithiol compound, benzene-1,3-diamidoethanethiol (BDETH2), also known as N,N'-bis(2-mercaptoethyl) isophthalamide or N,N'-bis(2-mercaptoethyl)-1,3-benzenedicarboxamide, capable of binding divalent metal ions, has been synthesized and characterized. A broad range of BDET-metal compounds, spanning the periodic chart, has been prepared and characterized by IR, MS, EA, Raman, XAFS and TGA. The characteristics of the BDET-M compounds were determined through secondary reactions. In an effort to derivatize BDET-M compounds through alkylalumination a new cyclic compound, 1,3- bis(4,5-dihydrothiazolo)benzene, has …
Pyridinium Bisretinoids: Synthesis And Photoactivated Cytotoxicity, Junping Gao
Pyridinium Bisretinoids: Synthesis And Photoactivated Cytotoxicity, Junping Gao
Theses and Dissertations
This thesis discusses pyridinium bisretinoid compounds (PBRs), which were prepared for two purposes: 1) to use them as standards for detection of novel fluorophores in human RPE cells, which may be involved in age-related macular degeneration (AMD), and 2) to use them in the development of a targeted and triggered drug delivery system for cancer therapy. We prepared a selection of PBRs using a one-pot biomimetic method; synthesis, mechanisms for formation, and characterization of these compounds is described. We also explored the photoreactivity of three novel PBR compounds and found that these PBRs form oxidation products under blue-light irradiation. The …
Pyridinium Bis-Retinoids A2-Dopamine And A2-Cadaverine: Implications In Age-Related Macular Degeneration And Cancer, Mckenzie Ruth Pew
Pyridinium Bis-Retinoids A2-Dopamine And A2-Cadaverine: Implications In Age-Related Macular Degeneration And Cancer, Mckenzie Ruth Pew
Theses and Dissertations
Age-related macular degeneration (AMD) is the leading cause of blindness in the United States of America. The pyridinium bis-retinoid A2-ethanolamine (A2E) has been implicated to play a role in AMD. We have observed novel pyridinium bis-retinoids through melanolipofuscin and human RPE extractions that may also play a role in the pathology of AMD. We have begun the construction of an amino-retinoid library in order to identify these ocular compounds. The compounds from the amino-retinoid library are also used in a targeted and triggered drug delivery system for treating cancer. Folic acid is coupled with the amino-retinoids to specifically target cancer …