Physical Sciences and Mathematics Commons^™

Joint Linear And Nonlinear Computation With Data Encryption For Efficient Privacy-Preserving Deep Learning, Qiao Zhang

Electrical & Computer Engineering Theses & Dissertations

Deep Learning (DL) has shown unrivalled performance in many applications such as image classification, speech recognition, anomalous detection, and business analytics. While end users and enterprises own enormous data, DL talents and computing power are mostly gathered in technology giants having cloud servers. Thus, data owners, i.e., the clients, are motivated to outsource their data, along with computationally-intensive tasks, to the server in order to leverage the server’s abundant computation resources and DL talents for developing cost-effective DL solutions. However, trust is required between the server and the client to finish the computation tasks (e.g., conducting inference for the newly-input …

Design, Synthesis And Characterization Of Carbohydrate Based Macrocycles, Photo Responsive Derivatives, And Glycoconjugates Based Low Molecular Weight Gelators, Surya Bahadur Adhikari

Chemistry & Biochemistry Theses & Dissertations

Functional glycoconjugates are important classes of compounds with many applications in different research fields. Our lab has been studying the synthesis and applications of different classes of glycoconjugates ranging from macrocycles to sugar heterocycle derivatives. Due to the importance of these compounds, our research is based on development of synthetic methods for various carbohydrate derivatives. This dissertation includes introduction and overview of projects, followed by the synthesis and studies of several different series of glycomacrolactones. The second project focuses on two classes of photoresponsive molecules, the coumarins and diarylethenes. The third project involves the synthesis and self-assembling properties of isoxazole-based …

Genetically Engineered Thermosynechococcus Elongatus Bp1: Assessment Of Potential Biorisks And Biofuel Production, Thu Ho Anh Nguyen-Jones

Chemistry & Biochemistry Theses & Dissertations

According to the International Energy Outlook 2019, released by the U.S. Energy Information Administration, it is projected that the energy consumption will increase up to 50% between 2018 and 2050 worldwide. As fossil fuel being a finite source of energy with the risk of depletion, many countries are now facing an energy security crisis. Therefore, it is important to develop other renewable and sustainable energy sources that will allow countries to shift away from depending on fossil fuels. Among several types of renewable energy, biofuel production using genetically engineered cyanobacteria is capturing much interest due to its many advantages. Different …

Space Charge Effects In Low Energy Magnetized Electron Beams, W. M. Sajini Anushika Kumari Wijethunga

Physics Theses & Dissertations

Magnetized electron cooling of the ion beam is one of the major approaches towards obtaining the required high luminosity in the proposed Electron-Ion Collider (EIC). To increase the cooling efficiency, a bunched electron beam with a high bunch charge and high repetition rate is required. However, these features can combine to enhance the collective interactions, such as the space charge effect. A magnetized electron beam was successfully generated at the Thomas Jefferson National Accelerator Facility (JLab) using a compact, 300 kV DC high voltage photo-gun with an inverted insulator geometry and bi-alkali antimonide photocathode. The beam magnetization was characterized using …

Phytoplankton Community Response To Upwelling Events: Distribution And Abundance Investigated Using Genomic Methods, Sveinn V. Einarsson

OES Theses and Dissertations

Upwelling events are known to support blooms of phytoplankton, important primary producers at the base of the oceanic food web. Phytoplankton community structure changes in response to upwelling support higher trophic level growth and increased efficiency of carbon export from the euphotic zone. While these events occur globally, this study examined upwelling in coastal regions, where alongshore winds can drive Ekman transport and upwelling of deeper waters. The two upwelling regimes examined were the California Current System and the Alaskan Beaufort Sea. In the California Current System, the relative diatom community composition was examined using 18S sequencing to determine how …

A Copula Model Approach To Identify The Differential Gene Expression, Prasansha Liyanaarachchi

Mathematics & Statistics Theses & Dissertations

Deoxyribonucleic acid, more commonly known as DNA, is a complex double helix-shaped molecule present in all living organisms and hosts thousands of genes. However, only a few genes exhibit differential expression and play a vital role in a particular disease such as breast cancer. Microarray technology is one of the modern technologies developed to study these gene expressions. There are two major microarray technologies available for expression analysis: Spotted cDNA array and oligonucleotide array. The focus of our research is the statistical analysis of data that arises from the spotted cDNA microarray. Numerous models have been proposed in the literature …

Shipboard Lidar As A Tool For Remotely Measuring The Distribution And Bulk Characteristics Of Marine Particles, Brian Leigh Collister

OES Theses and Dissertations

Light detection and ranging (lidar) can provide remote estimates of the vertical distribution of optical properties in the ocean, potentially revolutionizing our ability to characterize the spatial structure of upper ocean ecosystems. However, challenges associated with quantifying the relationship between lidar measurements and biogeochemical properties of interest have prevented its adoption for routinely mapping the vertical structure of marine ecosystems. To address this, we developed a shipboard oceanographic lidar that measures attenuation (α) and linear depolarization (δ) at scales identical to those of in-water optical and biogeochemical measurements. The instrument’s ability to resolve the distribution of optical and biogeochemical properties …

Synthesis And Characterization Of 4,6-Protected Glucosamine Derivatives And Branched Glycoconjugates, Jonathan Bietsch

Chemistry & Biochemistry Theses & Dissertations

Low molecular weight gelators (LMWGs) are small molecules that self-assemble in appropriate solvents to form three dimensional networks that immobilize the solvent, creating a supramolecular gel. The self-assembly of LMWGs occurs through non-covalent interactions such as hydrogen bonding, aromatic interactions, donor-acceptor interactions, Van der Waals interactions, hydrophobic forces, halogen bonding, etc. Due to self-assembly occurring through reversible non-covalent interactions, supramolecular gels can undergo a gel to solution transformation. Because of this, these materials can be sensitive to external stimuli such as temperature changes, pH changes, and other stimuli that effect non-covalent interactions. This makes the synthesis of LMWG’s an appealing …

Data-Driven Operational And Safety Analysis Of Emerging Shared Electric Scooter Systems, Qingyu Ma

Computational Modeling & Simulation Engineering Theses & Dissertations

The rapid rise of shared electric scooter (E-Scooter) systems offers many urban areas a new micro-mobility solution. The portable and flexible characteristics have made E-Scooters a competitive mode for short-distance trips. Compared to other modes such as bikes, E-Scooters allow riders to freely ride on different facilities such as streets, sidewalks, and bike lanes. However, sharing lanes with vehicles and other users tends to cause safety issues for riding E-Scooters. Conventional methods are often not applicable for analyzing such safety issues because well-archived historical crash records are not commonly available for emerging E-Scooters.

Perceiving the growth of such a micro-mobility …

Spatiotemporal Variations Of Precipitation And Climate-Resilient Structure Design In Virginia, Xiaomin Yang

Civil & Environmental Engineering Theses & Dissertations

How to consider effects of climate change on the design and management of hydrology related infrastructure is crucial but remains a challenge for sustaining resilient society. To address this challenge, existing hydrologic design procedures may need to be revised and/or redeveloped to take into account the precipitation non-stationarity resulting from climate change. Using the state of Virginia as a testbed and advanced statistical techniques such as nonparametric test, spatial autocorrelation, linear regression, distribution fitting, and spatial interpolation, this dissertation developed an innovative framework to detect the historical spatiotemporal variations of various precipitation characteristics, namely maximum precipitation intensity, precipitation amount, simple …

On The P-Inner Functions Of ℓPA, James G. Dragas

Mathematics & Statistics Theses & Dissertations

Define ℓ^p_A as the space of all functions holomorphic over the unit disk whose Taylor coefficients are p-summable. Despite their classical origins and simple definition, these spaces are not as well understood as one might expect. This is particularly true when compared with the Hardy spaces, which provide a useful road map for the types of questions we might consider reasonable. In this work we examine the zero sets of ℓ^p_A, p ∈ (1;∞), as well as a notion of inner function that is consistent with the approach taken on numerous other function spaces. …

Efficacy Of Sediment Contaminant Remediation Of The Benthos In A Segment Of The Southern Branch Of The Elizabeth River, Colton Martin

Biological Sciences Theses & Dissertations

The bottom sediment of the Southern Branch of the Elizabeth River, a tributary of Chesapeake Bay, was historically contaminated with hydrocarbons from industrial sources especially wood treatment facilities. The Elizabeth River Project selected a section of the bottom off Money Point in the Southern Branch for a sediment contaminant remediation effort. Prior to initiation of remediation efforts, a survey occurred in summer 2010 to characterize the ecological condition of the benthic communities off Money Point compared to benthic communities of a benthic region across the channel and northwest of Money Point near Blows Creek. That study characterized the benthos of …

Mobilizing Discomfort For Water Security As A Human Right: A Newspaper Analysis Of Social Conflict In South Africa, Madison Gonzalez

Graduate Program in International Studies Theses & Dissertations

There are 884 million people globally that do not have access to improved drinking water, while 2.5 billion do not have improved access to sanitation (Office of the High Commissioner for Human Rights, 2010). Those living in informal settlements and slums—what I call the ‘solidaric disaffiliated’ zones—represent one such location where individuals around the world have found themselves in a situation of neglected crisis as their geographic, economic, and social expulsion pushes them beyond the reach of opportunity and access to basic human rights such as water and sanitation. As individuals feel their dignity deteriorating due to the extreme precarity …

Estimating The Risk Of Future Plastic Marine Debris Resulting From The Urban Coastal Built Environment, Kelly C. Jones

OES Theses and Dissertations

The growing urban built environment in the coastal zone poses an unknown risk to the marine biosphere as a source of marine debris. Plastic, since its introduction in the mid- 1900s, is now used in nearly all aspects of human life. Growth in human population and urbanization in coastal zones has resulted in the accumulation of large stocks of plastic in the coastal built environment, and these stocks are still growing exponentially. The coastal zone is exposed to a number of hazards including storms, tsunamis, and sea level rise, and most of these hazards are expected to change in the …

Empirical Modeling Of Tilt-Rotor Aerodynamic Performance, Michael C. Stratton

Mechanical & Aerospace Engineering Theses & Dissertations

There has been increasing interest into the performance of electric vertical takeoff and landing (eVTOL) aircraft. The propellers used for the eVTOL propulsion systems experience a broad range of aerodynamic conditions, not typically experienced by propellers in forward flight, that includes large incidence angles relative to the oncoming airflow. Formal experiment design and analysis techniques featuring response surface methods were applied to a subscale, tilt-rotor wind tunnel test for three, four, five, and six blade, 16-inch diameter, propeller configurations in support of development of the NASA LA-8 aircraft. Investigation of low-speed performance included a maximum speed of 12 m/s and …

Connectivism: Adopting Quantum Holism In International Relations, Grant Randal Highland

Graduate Program in International Studies Theses & Dissertations

The current scientific context of both quantum science and an ever-increasingly connected global citizenry has set the conditions for a new perspective whereby the social sciences are on the cusp of adopting a quantum approach of probability and potentiality versus the clockwork mechanistic determinism of cause-and-effect Newtonian mechanics. While a scientific realist approach toward the application of quantum science to the social sciences is germane, there is a valid reason international relations should also consider and adopt the philosophical worldviews outside the genealogical canon of our early western forbears, as well as the philosophical explorations of consciousness and humanism which …

State Antifragility: An Agent-Based Modeling Approach To Understanding State Behavior, Rebecca Lee Law

Graduate Program in International Studies Theses & Dissertations

This dissertation takes an interdisciplinary approach to understanding what makes states antifragile and why this matters by constructing a parsimonious, first of its kind agent-based model. The model focuses on the key elements of state antifragility that reside along a spectrum of fragility and transverse bidirectionally from fragile to resilient to antifragile given a certain set of environmental conditions.

First coined by Nicholas Nassim Taleb and applied to economics, antifragility is a nascent concept. In 2015, Nassim Taleb and Gregory Treverton’s article in Foreign Affairs outlined five characteristics of state antifragility. This project aims to advance the study of anti-fragility …

High-Order Positivity-Preserving L2-Stable Spectral Collocation Schemes For The 3-D Compressible Navier-Stokes Equations, Johnathon Keith Upperman

Mathematics & Statistics Theses & Dissertations

High-order entropy stable schemes are a popular method used in simulations with the compressible Euler and Navier-Stokes equations. The strength of these methods is that they formally satisfy a discrete entropy inequality which can be used to guarantee L₂ stability of the numerical solution. However, a fundamental assumption that is explicitly or implicitly used in all entropy stability proofs available in the literature for the compressible Euler and Navier-Stokes equations is that the thermodynamic variables (e.g., density and temperature) are strictly positive in the entire space{time domain considered. Without this assumption, any entropy stability proof for a numerical scheme …

Computational Analysis Of Type 3 Iodothyronine Deiodinase: Potential Inhibitors, Substrate Binding, And Dimer Structure, Eric Scott Marsan

Chemistry & Biochemistry Theses & Dissertations

Thyroid hormones (THs) in mammalian tissues are crucial for development and maintaining metabolic homeostasis. Iodothyronine deiodinases (Dios) remove iodines from THs by a selenocysteine (Sec) residue, which either activates or inactivates them. Halogen bonding (XB) has been proposed to describe the interaction between the Se and I atoms of the T4-Dio complex. Disruption of TH homeostasis by xenobiotics, such as polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) can cause deleterious effects on the endocrine system. Experimental studies have indicated that PBDEs and PCBs could disrupt TH homeostasis by inhibiting Dio through XB formation. However, no current quantitative study exists …

Development And Applications Of Adjoint-Based Aerodynamic And Aeroacoustic Multidisciplinary Optimization For Rotorcraft, Ramiz Omur Icke

Mechanical & Aerospace Engineering Theses & Dissertations

Urban Air Mobility (UAM) is one of the most popular proposed solutions for alleviating traffic problems in populated areas. In this context, the proposed types of vehicles mainly consist of rotors and propellers powered by electric motors. However, those rotary-wing components can contribute excessively to noise generation. Therefore, a significant noise concern emerges due to urban air vehicles in or around residential areas. Reducing noise emitted by air vehicles is critically important to improve public acceptance of such vehicles for operations in densely populated areas.

Two main objectives of the present dissertation are: (1) to expand the multidisciplinary optimization to …

A Digital One Degree Of Freedom Model Of An Electromagnetic Position Sensor, Michelle Elizabeth Weinmann

Mechanical & Aerospace Engineering Theses & Dissertations

The purpose of this project was to improve an existing system currently in use by NASA Langley Research Center (LaRC). The 6-inch Magnetic Suspension and Balance System (MSBS) built at MIT is operational with control in three degrees of freedom, with two additional degrees of freedom exhibiting passive stability. The means for measuring model displacement within the magnetic environment is an Electromagnetic Position Sensor (EPS), consisting of excitation coils at 20 kHz and multiple sets of pickup coils. The pickup coil voltages are proportional to model displacement in each degree of freedom. However, the EPS electronic signal processing system is …

Riverology: Promoting Stewardship Of Rivers Through Youth Participation In Science And Art, Robin R. Dunbar

Institute for the Humanities Theses

This project focuses on mentoring children to help reduce marine debris in their local river by implementing one of ten lessons from an inquiry-based Riverology curriculum to empower youth voice, increase geo-literacy, and spatial thinking. Eighteen participants aged seven and eight, piloted Riverology Lesson 2: What Do I Know or Imagine about the Elizabeth River? that includes six steps: inquire, visualize, draw, share, act, and reflect. The children were asked to make drawings before and after viewing an Elizabeth River Story Map presentation (Dunbar, 2021a). The drawings were then compared to see if the participants included marine debris, stewardship solutions, …

Move: Mobile Observers Variants And Extensions, Ryan Florin

Computer Science Theses & Dissertations

Traffic state estimation is a fundamental task of Intelligent Transportation Systems. Recent advances in sensor technology and emerging computer and vehicular communications paradigms have brought the task of estimating traffic state parameters in real-time within reach.

This has led to the main research question of this thesis: Can a vehicle accurately estimate traffic parameters using onboard resources shared through CV technology in a lightweight manner without utilizing centralized or roadside infrastructure?

In 1954 Wardrop and Charlesworth proposed the Moving Observer method to measure traffic parameters based on an observed number of vehicle passes. We start by proposing methods for detecting …

Examining Melt Pond Dynamics And Light Availability In The Arctic Ocean Via High Resolution Satellite Imagery, Austin Wesley Abbott

OES Theses and Dissertations

As the Arctic experiences consequences of climate change, a shift from thicker, multi-year ice to thinner, first-year ice has been observed. First-year ice is prone to extensive pools of meltwater (“melt ponds”) forming on its surface, which enhance light transmission to the ocean. Changes in the timing and distribution of melt pond formation and associated increases in under-ice light availability are the primary drivers for seasonal progression of water column primary production and warming. Observations of melt pond development and distribution require meter scale resolution and have traditionally been limited to airborne images. However, recent advances in high spatial resolution …

Physiological And Molecular Responses Of Eurythermal And Stenothermal Populations Of Zostera Marina L (Eelgrass) To Climate Change, Carmen C. Zayas-Santiago

OES Theses and Dissertations

As CO₂ levels in Earth’s atmosphere and oceans steadily rise, varying organismal responses may produce ecological losers and winners. Increased ocean CO₂ can enhance seagrass productivity and thermal tolerance, providing some compensation for climate warming. However, the consistency of this CO₂ effect across populations of cosmopolitan species such as Zostera marina L. (eelgrass) remains largely unknown. This study analyzed whole-plant performance metabolic profiles and gene expression patterns of distinct eelgrass populations in response to CO₂ enrichment. Populations were transplanted from Nisqually Landing and Dumas Bay, two cold water environments in Puget Sound, WA (USA) that rarely …

Numerical Calculation Of Losses Of Trapped Vortices Under Strong Rf Meissner Current And Dc Superheating Field In Type Ii Superconductors, Walive Pathiranage Manula Randhika Pathirana

Physics Theses & Dissertations

Research on the vortex dynamics and enhancing of superheating field in superconductors has attracted much attention in accelerator physics community to develop next-generation high-performance accelerator cavities. However, the extreme dynamics of curvilinear elastic vortices driven by very strong currents close to the depairing limit or superheating field of a superconductor with a nanostructured surface has not been well understood. We calculated the superheating field H_sh and critical momentum kc characterizing the wavelength of the instability λ_m of the Meissner state to flux penetration by solving numerically the Ginzburg-Landau equations. A bulk superconductor, superconductor with the inhomogeneous surface disorder …

Improvement Of Biochar Through Ozonization And Biosafety Of Genetically Engineered Cyanobacteria, Oumar Sacko

Chemistry & Biochemistry Theses & Dissertations

Through the innovative technique of biochar post-production surface oxygenation by ozonization, we were able to improve certain properties of biochar. In project one, the incubation of an insoluble phosphate rock material (hydroxyapatite) with the wet ozonized pine 400 biochar and its filtrate resulted in a solubilization of 80 times more phosphate from hydroxyapatite (569.0 mg/L ± 6.4) compared to the pure water-hydroxyapatite control (7.2 mg/L ± 0.3). The ozonized biochar may provide a new possible way to unlock the phosphorus from insoluble phosphate mineral phases. The cation exchange capacity (CEC) is a key property of biochar when used as a …

Deep Learning Approaches For Seagrass Detection In Multispectral Imagery, Kazi Aminul Islam

Electrical & Computer Engineering Theses & Dissertations

Seagrass forms the basis for critically important marine ecosystems. Seagrass is an important factor to balance marine ecological systems, and it is of great interest to monitor its distribution in different parts of the world. Remote sensing imagery is considered as an effective data modality based on which seagrass monitoring and quantification can be performed remotely. Traditionally, researchers utilized multispectral satellite images to map seagrass manually. Automatic machine learning techniques, especially deep learning algorithms, recently achieved state-of-the-art performances in many computer vision applications. This dissertation presents a set of deep learning models for seagrass detection in multispectral satellite images. It …

Wiener-Fliess Composition Of Formal Power Series: Additive Static Feedback And Shuffle Rational Series, Subbarao Venkatesh Guggilam

Electrical & Computer Engineering Theses & Dissertations

The problem statement for this dissertation is two-fold. The first problem considered is when does a Chen-Fliess series in an additive static feedback connection with a formal static map yield a closed-loop system with a Chen-Fliess series expansion? This work proves that such a closed-loop system always has a Chen-Fliess series representation. Furthermore, an algorithm based on the Hopf algebras for the shuffle group and the dynamic output feedback group is designed to compute the generating series of the closed-loop system. It is proved that the additive static feedback connection preserves local convergence and relative degree, but a counterexample shows …

Molecular Dynamics Simulations Of Ion Transport Through Electrically Stressed Biological Membranes, Federica Castellani

Biomedical Engineering Theses & Dissertations

The cell membrane is a selectively permeable barrier that controls the transport of ions, molecules, and other materials into and out of a cell. The manipulation of the cell membrane permeability is the basis for several biotechnological and biomedical applications, including electroporation. Electroporation (or electropermeabilization) occurs when the application of an external electric pulse causes water intrusion into the membrane interior and the formation of conductive transmembrane electropores. These electropores allow drugs, genetic material, and other normally impermeant molecules to enter a cell. Despite years of study, the complex mechanisms underlying this process are still not well understood. Molecular dynamics …