Physical Sciences and Mathematics Commons^™

Assessing Extant Methods For Generating G-Optimal Designs And A Novel Methodology To Compute The G-Score Of A Candidate Design, Hyrum John Hansen

All Graduate Theses and Dissertations, Fall 2023 to Present

Experimental designs are used by scientists to allocate treatments such that statistical inference is appropriate. Most traditional experimental designs have mathematical properties that make them desirable under certain conditions. Optimal experimental designs are those where the researcher can exercise total control over the treatment levels to maximize a chosen mathematical property. As is common in literature, the experimental design is represented as a matrix where each column represents a variable, and each row represents a trial. We define a function that takes as input the design matrix and outputs its score. We then algorithmically adjust each entry until a design …

Interpretable Word-Level Sentiment Analysis With Attention-Based Multiple Instance Classification Models, Chenyu Yang

Statistical Science Theses and Dissertations

In this study, our main objective is to tackle the black-box nature of popular machine learning models in sentiment analysis and enhance model interpretability. We aim to gain more insight into the decision-making process of sentiment analysis models, which is often obscure in those complex models. To achieve this goal, we introduce two word-level sentiment analysis models.

The first model is called the attention-based multiple instance classification (AMIC) model. It combines the transparent model structure of multiple instance classification and the self-attention mechanism in deep learning to incorporate the contextual information from documents. As demonstrated by a wine review dataset …

Bayesian Statistical Modeling Of Spatially Resolved Transcriptomics Data, Xi Jiang

Statistical Science Theses and Dissertations

Spatially resolved transcriptomics (SRT) quantifies expression levels at different spatial locations, providing a new and powerful tool to investigate novel biological insights. As experimental technologies enhance both in capacity and efficiency, there arises a growing demand for the development of analytical methodologies.

One question in SRT data analysis is to identify genes whose expressions exhibit spatially correlated patterns, called spatially variable (SV) genes. Most current methods to identify SV genes are built upon the geostatistical model with Gaussian process, which could limit the models' ability to identify complex spatial patterns. In order to overcome this challenge and capture more types …

A Comparison Of Confidence Intervals In State Space Models, Jinyu Du

Statistical Science Theses and Dissertations

This thesis develops general procedures for constructing confidence intervals (CIs) of the error disturbance parameters (standard deviations) and transformations of the error disturbance parameters in time-invariant state space models (ssm). With only a set of observations, estimating individual error disturbance parameters accurately in the presence of other unknown parameters in ssm is a very challenging problem. We attempted to construct four different types of confidence intervals, Wald, likelihood ratio, score, and higher-order asymptotic intervals for both the simple local level model and the general time-invariant state space models (ssm). We show that for a simple local level model, both the …

Optimal Experimental Planning Of Reliability Experiments Based On Coherent Systems, Yang Yu

Statistical Science Theses and Dissertations

In industrial engineering and manufacturing, assessing the reliability of a product or system is an important topic. Life-testing and reliability experiments are commonly used reliability assessment methods to gain sound knowledge about product or system lifetime distributions. Usually, a sample of items of interest is subjected to stresses and environmental conditions that characterize the normal operating conditions. During the life-test, successive times to failure are recorded and lifetime data are collected. Life-testing is useful in many industrial environments, including the automobile, materials, telecommunications, and electronics industries.

There are different kinds of life-testing experiments that can be applied for different purposes. …

Optimizing Tumor Xenograft Experiments Using Bayesian Linear And Nonlinear Mixed Modelling And Reinforcement Learning, Mary Lena Bleile

Statistical Science Theses and Dissertations

Tumor xenograft experiments are a popular tool of cancer biology research. In a typical such experiment, one implants a set of animals with an aliquot of the human tumor of interest, applies various treatments of interest, and observes the subsequent response. Efficient analysis of the data from these experiments is therefore of utmost importance. This dissertation proposes three methods for optimizing cancer treatment and data analysis in the tumor xenograft context. The first of these is applicable to tumor xenograft experiments in general, and the second two seek to optimize the combination of radiotherapy with immunotherapy in the tumor xenograft …

Development Of Bayesian Hierarchical Methods Involving Meta-Analysis, Jackson Barth

Statistical Science Theses and Dissertations

When conducting statistical analysis in the Bayesian paradigm, the most critical decision made by the researcher is the identification of a prior distribution for a parameter. Despite the mathematical soundness of the Bayesian approach, a wrongly specified prior can lead to biased and incorrect results. To avoid this, prior distributions should be based on real data, which are easily accessible in the "big data" era. This dissertation explores two applications of Bayesian hierarchical modelling that incorporate information obtained from a meta-analysis.

The first of these applications is in the normalization of genomics data, specifically for nanostring nCounter datasets. A meta-analysis …

Empirical Likelihood Ratio Tests For Homogeneity Of Distributions Of Component Lifetimes From System Lifetime Data With Known System Structures, Jingjing Qu

Statistical Science Theses and Dissertations

In system reliability, practitioners may be interested in testing the homogeneity of the component lifetime distributions based on system lifetimes from multiple data sources for various reasons, such as identifying the component supplier that provides the most reliable components.

In the first part of the dissertation, we develop distribution-free hypothesis testing procedures for the homogeneity of the component lifetime distributions based on system lifetime data when the system structures are known. Several nonparametric testing statistics based on the empirical likelihood method are proposed for testing the homogeneity of two or more component lifetime distributions. The computational approaches to obtain the …

Using A Distributive Approach To Model Insurance Loss, Kayla Kippes

Student Research Submissions

Insurance loss is an unpredicted event that stands at the forefront of the insurance industry. Loss in insurance represents the costs or expenses incurred due to a claim. An insurance claim is a request for the insurance company to pay for damage caused to an individual’s property. Loss can be measured by how much money (the dollar amount) has been paid out by the insurance company to repair the damage or it can be measured by the number of claims (claim count) made to the insurance company. Insured events include property damage due to fire, theft, flood, a car accident, …

Length Bias Estimation Of Small Businesses Lifetime, Simeng Li

Honors Theses

Small businesses, particularly restaurants, play a crucial role in the economy by generating employment opportunities, boosting tourism, and contributing to the local economy. However, accurately estimating their lifetimes can be challenging due to the presence of length bias, which occurs when the likelihood of sampling any particular restaurant's closure is influenced by its duration in operation. To address the issue, this study conducts goodness-of-fit tests on exponential/gamma family distributions and employs the Kaplan-Meier method to more accurately estimate the average lifetime of restaurants in Carytown. By providing insights into the challenges of estimating the lifetimes of small businesses, this study …

Influence Diagnostics For Generalized Estimating Equations Applied To Correlated Categorical Data, Louis Vazquez

Statistical Science Theses and Dissertations

Influence diagnostics in regression analysis allow analysts to identify observations that have a strong influence on model fitted probabilities and parameter estimates. The most common influence diagnostics, such as Cook’s Distance for linear regression, are based on a deletion approach where the results of a model with and without observations of interest are compared. Here, deletion-based influence diagnostics are proposed for generalized estimating equations (GEE) for correlated, or clustered, nominal multinomial responses. The proposed influence diagnostics focus on GEEs with the baseline-category logit link function and a local odds ratio parameterization of the association structure. Formulas for both observation- and …

High-Dimensional Variable Selection Via Knockoffs Using Gradient Boosting, Amr Essam Mohamed

Dissertations

As data continue to grow rapidly in size and complexity, efficient and effective statistical methods are needed to detect the important variables/features. Variable selection is one of the most crucial problems in statistical applications. This problem arises when one wants to model the relationship between the response and the predictors. The goal is to reduce the number of variables to a minimal set of explanatory variables that are truly associated with the response of interest to improve the model accuracy. Effectively choosing the true influential variables and controlling the False Discovery Rate (FDR) without sacrificing power has been a challenge …

Modeling The Probability Of A Successful Stolen Base Attempt In Major League Baseball, Cade Stanley

Senior Theses

In Major League Baseball (MLB), the outcome of a stolen base attempt has important implications. Success moves the runner closer to scoring, while failure records an out and removes the runner from the basepaths altogether. Therefore, it is important that the decision by a coach or player to steal a base is well-informed. In this thesis, I explore a statistical approach to making this decision. I train logistic regression and random forest models, using data about the game situation and about the runner, pitcher, and catcher involved in the stolen base attempt, to estimate the probability that a stolen base …

Regression Modeling Of Complex Survival Data Based On Pseudo-Observations, Rong Rong

Statistical Science Theses and Dissertations

The restricted mean survival time (RMST) is a clinically meaningful summary measure in studies with survival outcomes. Statistical methods have been developed for regression analysis of RMST to investigate impacts of covariates on RMST, which is a useful alternative to the Cox regression analysis. However, existing methods for regression modeling of RMST are not applicable to left-truncated right-censored data that arise frequently in prevalent cohort studies, for which the sampling bias due to left truncation and informative censoring induced by the prevalent sampling scheme must be properly addressed. Meanwhile, statistical methods have been developed for regression modeling of the cumulative …

Bayesian Estimation Of The Intensity Function Of A Non-Homogeneous Poisson Process, James Jensen

Theses

In this paper we explore Bayesian inference and its application to the problem of estimating the intensity function of a non-homogeneous Poisson process. These processes model the behavior of phenomena in which one or more events, known as arrivals, occur independently of one another over a certain period of time. We are concerned with the number of events occurring during particular time intervals across several realizations of the process. We show that given sufficient data, we are able to construct a piecewise-constant function which accurately estimates the mean rates on particular intervals. Further, we show that as we reduce these …

The Microscopical Evidence Traces Analysis Of Household Dust And Its Statistical Significance As A Definitive Identification Technique, Stephanie Polifroni

Dissertations, Theses, and Capstone Projects

Evidence found at crime scenes is used to assist in creating a link the suspect, the victim, and the scene. As stated by the Locard’s Principle, every contact leaves a trace, that evidence can be used to link together an investigation. Traces are collected in hopes that they can be identified and associated to an individual or individuals to help solve that particular crime. However, the strongest conclusion for evidence traces is an association to a source, and unless a physical match of some kind is found, an individualization cannot be established even when known sample is available. However, having …

Dynamic Prediction For Alternating Recurrent Events Using A Semiparametric Joint Frailty Model, Jaehyeon Yun

Statistical Science Theses and Dissertations

Alternating recurrent events data arise commonly in health research; examples include hospital admissions and discharges of diabetes patients; exacerbations and remissions of chronic bronchitis; and quitting and restarting smoking. Recent work has involved formulating and estimating joint models for the recurrent event times considering non-negligible event durations. However, prediction models for transition between recurrent events are lacking. We consider the development and evaluation of methods for predicting future events within these models. Specifically, we propose a tool for dynamically predicting transition between alternating recurrent events in real time. Under a flexible joint frailty model, we derive the predictive probability of …

Efficient Approaches To Steady State Detection In Multivariate Systems, Honglun Xu

Open Access Theses & Dissertations

Steady state detection is critically important in many engineering fields such as fault detection and diagnosis, process monitoring and control. However, most of the existing methods are designed for univariate signals. In this dissertation, we proposed an efficient online steady state detection method for multivariate systems through a sequential Bayesian partitioning approach. The signal is modeled by a Bayesian piecewise constant mean and covariance model, and a recursive updating method is developed to calculate the posterior distributions analytically. The duration of the current segment is utilized to test the steady state. Insightful guidance is provided for hyperparameter selection. The effectiveness …

Applications Of Machine Learning Algorithms In Materials Science And Bioinformatics, Mohammed Quazi

Mathematics & Statistics ETDs

The piezoelectric response has been a measure of interest in density functional theory (DFT) for micro-electromechanical systems (MEMS) since the inception of MEMS technology. Piezoelectric-based MEMS devices find wide applications in automobiles, mobile phones, healthcare devices, and silicon chips for computers, to name a few. Piezoelectric properties of doped aluminum nitride (AlN) have been under investigation in materials science for piezoelectric thin films because of its wide range of device applicability. In this research using rigorous DFT calculations, high throughput ab-initio simulations for 23 AlN alloys are generated.

This research is the first to report strong enhancements of piezoelectric properties …

Generating A Dataset For Comparing Linear Vs. Non-Linear Prediction Methods In Education Research, Jack Mauro, Elena Martinez, Anna Bargagliotti

Honors Thesis

Machine learning is often used to build predictive models by extracting patterns from large data sets. Such techniques are increasingly being utilized to predict outcomes in the social sciences. One such application is predicting student success. Machine learning can be applied to predicting student acceptance and success in academia. Using these tools for education-related data analysis, may enable the evaluation of programs, resources and curriculum. Currently, research is needed to examine application, admissions, and retention data in order to address equity in college computer science programs. However, most student-level data sets contain sensitive data that cannot be made public. To …

The Efficacy Of The Covid-19 Vaccine In Mississippi, Ilyse Miriam Levy

Honors Theses

The Efficacy of The COVID-19 Vaccine in Mississippi

(Under the direction of Dr. Xin Dang)

By tracking and analyzing fifty-three weeks of COVID-19 data, this thesis analyzes the efficacy of the COVID-19 vaccine within the State of Mississippi. Over the course of these fifty-three weeks, I have also been able to calculate the confidence intervals for vaccination efficacy and the risk reduction due to vaccination by using data regarding the correlations between deaths and vaccination status, provided to me by the Mississippi Office of Epidemiology. My analysis demonstrates that the COVID-19 vaccine is effective not only in Mississippi but also …

An Examination Of The Statistics And Risk Management Concepts Behind The Patient Protection And Affordable Care Act (Ppaca) Of 2010, Scott Sinclair

Undergraduate Honors Thesis Collection

The Patient Protection and Affordable Care Act (PPACA) is the overarching federal law that has impacted the intricacies of the health insurance market for more than a decade. Using the supervised learning method of multiple linear regression, the relationship between the medical loss ratio rebates and predictor variables such as the state, health insurance market, and the number of insurance companies owing rebates will be analyzed, along with the actuarial value of metal tiers and geographic rating area factors in terms of their relationship to the insurance premium for a standard family of four, defined as a forty-year-old couple with …

Forecasting Razorback Baseball Game Outcomes, Austin Raabe

Information Systems Undergraduate Honors Theses

Despite the disappointing end to the 2021 Arkansas Razorback baseball year, the team’s success provided hog fans something to look forward to next season. While they will be without the 2021 Golden Spikes Award winner, Kevin Kopps, and four All-SEC team selections, the 2022 roster has promising new and returning talent. With fifty percent of the players who played significant time last year coming back (minimum ten hits or ten innings pitched), the arrival of several impact transfers from major conferences, and a recruiting class ranked in the top five according to Perfect Game, there is reason to believe that …

Understanding And Improving The System: The Effects Of Weighting On The Accuracy Of Political Polling In Arkansas, Beck Williams

Political Science Undergraduate Honors Theses

In an effort to increase the accuracy of statewide political polling in Arkansas, we explore the statistical strategy of weighting with a focus on one yearly opinion poll: The Arkansas Poll. We conduct over 70 weighting experiments on the 2016 and 2020 Arkansas Polls using a variety of variables and opinion questions. From these experiments, we find that while some weighted variables tend to create larger changes, weighting typically results in a single-digit percentage change that does not substantially shift or “flip” the majorities. Due to a greater rate of change through weighting in the 2020 Poll compared to the …

Analytical Study To Determine Significant Causes Of Increased No-Hitters In The 2021 Major League Baseball Season, Joel Robison

Honors Projects

Why were there so many no-hitters in the 2021 MLB season? This project focuses on possible significant causes to the record-breaking number of no-hitters pitched in the 2021 Major League Baseball season. Specifically, this project takes an analytical look at the recent trends in launch angles and spin rates to determine if there are any significant causes to the increased number of no-hitters in baseball. The random nature and unpredictability of the game of baseball make it almost impossible to come to any solid conclusions.

Finding The Best Predictors For Foot Traffic In Us Seafood Restaurants, Isabel Paige Beaulieu

Honors Theses and Capstones

COVID-19 caused state and nation-wide lockdowns, which altered human foot traffic, especially in restaurants. The seafood sector in particular suffered greatly as there was an increase in illegal fishing, it is made up of perishable goods, it is seasonal in some places, and imports and exports were slowed. Foot traffic data is useful for business owners to have to know how much to order, how many employees to schedule, etc. One issue is that the data is very expensive, hard to get, and not available until months after it is recorded. Our goal is to not only find covariates that …

Using Deep Neural Networks To Analyze Precision Agriculture Data, Stephanie Liebl

Electronic Theses and Dissertations

As the population of the Earth increases, there is a growing need for food to feed the inhabitants. Precision agriculture offers techniques and tools that can be used to help accommodate the growing population. One specific precision agriculture tool is remote sensing data, which can be used to image fields as an effort to better predict or understand the crops. In this thesis, deep neural networks are used to evaluate various spatial, spectral, and temporal resolutions of three different satellite images to determine which best predicts corn yield. The main metrics we used to evaluate the models were R-squared (R2), …

A Monte Carlo Simulation Of Rat Choice Behavior With Interdependent Outcomes, Michelle A. Frankot

Graduate Theses, Dissertations, and Problem Reports

Preclinical behavioral neuroscience often uses choice paradigms to capture psychiatric symptoms. In particular, the subfield of operant research produces nested datasets with many discrete choices in a session. The standard analytic practice is to aggregate choice into a continuous variable and analyze using ANOVA or linear regression. However, choice data often have multiple interdependent outcomes of interest, violating an assumption of general linear models. The aim of the current study was to quantify the accuracy of linear mixed-effects regression (LMER) for analyzing data from a 4-choice operant task called the Rodent Gambling Task (RGT), which measures decision-making in the context …

The Classification Of Basket Neural Cells In The Mammalian Neocortex, Sreya Pudi

Senior Theses

Basket neuronal cells of the mammalian neocortex have been classically categorized into two or more groups. Originally, it was thought that the large and small types are the naturally occurring groups that emerge from reasons that relate to neurobiological function and anatomical position. Later, a study based on anatomical and physiological features of these neurons introduced a third type, the net basket cell which is intermediate in size as compared to the large and small types. In this study, multivariate analysis was used to test the hypothesis that the large and small types are morphologically distinct groups. The results of …

Data Analysis And Visualization To Dismantle Gender Discrimination In The Field Of Technology, Quinn Bolewicki

Dissertations, Theses, and Capstone Projects

In the United States, a significant population is facing an uphill battle trying to thrive in an industry that has seen exponential growth in recent years. Women, who account for approximately 50.8% of the U.S. population are statistically underpaid and underrepresented in science, technology, engineering, and mathematics (STEM). Despite women-led technology teams establishing a 21% greater return on investment than teams who don’t, and young women largely outperforming men in math according to a 2015 study, there are only three fortune 500 companies led by women, and they comprise only 10% of internet entrepreneurs. Research generates hundreds of articles, infographics, …