Physical Sciences and Mathematics Commons^™

Stressors Across The Lifespan And Dementia Risk: A Statistical Method Analysis, Megan Platt Borrowman

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

The Cache Lifespan Stressors and Alzheimer's Disease (LSAD) study has access to data from the Cache County Study on Memory Health and Aging (CCS) that have been linked to the extensive genealogical and vital records from the Utah Population Database (UPDB). Information about stressful life events experienced by the original 5092 CCS participants has been extracted objectively from the UPDB, without the possibility of recall bias. This information was then statistically analyzed to look for relationships between key stressors and dementia risk. The LSAD study made it possible to examine the correlation between stressors as well as look at patterns …

Perceived Parent-Child Relationship And High-Risk Behaviors Among Christian College Students, Karla G. Lavin Williams

Loma Linda University Electronic Theses, Dissertations & Projects

Background. Adolescents and young adults today are participating in high-risk behaviors such as dangerous sexual behaviors and drug and alcohol abuse at high rates. An increased incidence of negative effects associated with the aforementioned behaviors has led researchers to examine factors that influence and protect adolescents from certain devastating effects (Davis, Hendershot, George, Norris, & Heiman, 2007; Goldstein, Bamett, Pedlow, & Murphy, 2007; Hamilton, et al., 2007; Hingson, Heeren, & Winter, 2006; Hingson, Heeren, Winter, & Wechsler, 2003; Hingson, Heeren, Zakocs, Winter, & Wechsler, 2003; McCarty, et al., 2004; Mokdad, Marks, Stroup, & Gerberding, 2004; Mosher, Chandra, & Jones, 2005; …

A Study Of Missing Data Imputation And Predictive Modeling Of Strength Properties Of Wood Composites, Yan Zeng

Masters Theses

Problem: Real-time process and destructive test data were collected from a wood composite manufacturer in the U.S. to develop real-time predictive models of two key strength properties (Modulus of Rupture (MOR) and Internal Bound (IB)) of a wood composite manufacturing process. Sensor malfunction and data “send/retrieval” problems lead to null fields in the company’s data warehouse which resulted in information loss. Many manufacturers attempt to build accurate predictive models excluding entire records with null fields or using summary statistics such as mean or median in place of the null field. However, predictive model errors in validation may be higher …

Exploring The Effectiveness Of Environmentally Sustainable Practices In Municipal Government: A Case Study Of The City Of Knoxville’S Department Of Parks And Recreation, Anthony Michael Brown

Masters Theses

Sustainability practices produce programs and services that meet current needs while preserving the environment and natural resources for the future. City parks and recreation departments are facing budget shortfalls and increasing expectations from customers. Governments are now embracing sustainability practices to create financial savings while also fostering relations with customers.

The purpose of this single case study was twofold: (1) to examine the effectiveness of one city department’s strategies in outsourcing its environmental sustainability program through a performance contract with Ameresco; and (2) to examine the perceptions of key department employees about the effectiveness of the sustainability initiative. A …

Gene By Bmi Interactions Influencing C-Reactive Protein Levels In European-Americans, Sarah Tudor

Dissertations & Theses (Open Access)

C-Reactive Protein (CRP) is a biomarker indicating tissue damage, inflammation, and infection. High-sensitivity CRP (hsCRP) is an emerging biomarker often used to estimate an individual’s risk for future coronary heart disease (CHD). hsCRP levels falling below 1.00 mg/l indicate a low risk for developing CHD, levels ranging between 1.00 mg/l and 3.00 mg/l indicate an elevated risk, and levels exceeding 3.00 mg/l indicate high risk. Multiple Genome-Wide Association Studies (GWAS) have identified a number of genetic polymorphisms which influence CRP levels. SNPs implicated in such studies have been found in or near genes of interest including: CRP, APOE, APOC, IL-6, …

Statistical Analysis Of Fatalities Due To Vehicle Accidents In Las Vegas, Nv, Annabelle Marie Mathis

UNLV Theses, Dissertations, Professional Papers, and Capstones

The goal of this thesis is to investigate factors that affect the odds of having a fatality in a vehicle collision. We will be looking at characteristics of the driver that caused the accident (age, gender, behavior, actions, influences, and seat belt worn), the characteristics of the vehicle the driver drove (type of vehicle, and air bag deployment), the characteristics of the environment in which the accident occurred (weather, road condition, lighting, time of day, the day of the week, and month of the year), the characteristics of the crash (direction of accident and how many vehicles were involved), and …

Impact Of An Online Support System On Health Related Quality Of Life Among Men Diagnosed With Prostate Cancer, Daniel K. Osei

Loma Linda University Electronic Theses, Dissertations & Projects

Prostate cancer is a major public health issue worldwide and a significant cause of male cancer death in the USA. Though early screening and treatment has greatly enhanced the outcome, men diagnosed with prostate cancer face problems that compromise quality of life after treatment. Online support for prostate cancer clients is a convenient way to help because it is anonymous, inexpensive, and can be used at clients’ convenience. Yet few studies have explored how these supports impact these clients. This study used a longitudinal randomized experimental design to examine the impact of online services on quality of life of prostate …

Prediction Of Dna Methylation Based On Genomic Architecture And Applications Of Positional Weight Matrices, Juan Gallegos

Dissertations & Theses (Open Access)

Gene silencing due to epigenetic mechanisms shows evidence of significant contributions to cancer development. We hypothesis that the genetic architecture based on retrotransposon elements surrounding the transcription start site, plays an important role in the suppression and promotion of DNA methylation. In our investigation we found a high rate of SINE and LINEs retrotransposon elements near the transcription start site of unmethylated genes when compared to methylated genes. The presence of these elements were positively associated with promoter methylation, contrary to logical expectations, due to the malicious effects of retrotransposon elements which insert themselves randomly into the genome causing possible …

Mixture Model Cluster Analysis Under Different Covariance Structures Using Information Complexity, Bahar Erar

Masters Theses

In this thesis, a mixture-model cluster analysis technique under different covariance structures of the component densities is developed and presented, to capture the compactness, orientation, shape, and the volume of component clusters in one expert system to handle Gaussian high dimensional heterogeneous data sets to achieve flexibility in currently practiced cluster analysis techniques. Two approaches to parameter estimation are considered and compared; one using the Expectation-Maximization (EM) algorithm and another following a Bayesian framework using the Gibbs sampler. We develop and score several forms of the ICOMP criterion of Bozdogan (1994, 2004) as our fitness function; to choose the number …

Bayesian Phase I Dose Finding In Cancer Trials, Lin Yang

Dissertations & Theses (Open Access)

This dissertation explores phase I dose-finding designs in cancer trials from three perspectives: the alternative Bayesian dose-escalation rules, a design based on a time-to-dose-limiting toxicity (DLT) model, and a design based on a discrete-time multi-state (DTMS) model.

We list alternative Bayesian dose-escalation rules and perform a simulation study for the intra-rule and inter-rule comparisons based on two statistical models to identify the most appropriate rule under certain scenarios. We provide evidence that all the Bayesian rules outperform the traditional ``3+3'' design in the allocation of patients and selection of the maximum tolerated dose.

The design based on a time-to-DLT model …

An Analysis Of Boosted Regression Trees To Predict The Strength Properties Of Wood Composites, Dillon Matthew Carty

Masters Theses

The forest products industry is a significant contributor to the U.S. economy contributing six percent of the total U.S. manufacturing gross domestic product (GDP), placing it on par with the U.S. automotive and plastics industries. Sustaining business competitiveness by reducing costs and maintaining product quality will be essential in the long term for this industry. Improved production efficiency and business competitiveness is the primary rationale for this work. A challenge facing this industry is to develop better knowledge of the complex nature of process variables and their relationship with final product quality attributes. Quantifying better the relationships between process variables …

A Comparison Of Spatio-Temporal Prediction Methods Of Cancer Incidence In The U.S, Michelle Hamlyn

UNLV Theses, Dissertations, Professional Papers, and Capstones

Cancer is the cause of one out of four deaths in the United States, and in 2009, researchers expected over 1.5 million new patients to be diagnosed with some form of cancer. People diagnosed with cancer, whether a common or rare type, need to undergo treatments, the amount and kind of which will depend on the severity of the cancer. So how do healthcare providers know how much funding is needed for treatment? What would better enable a pharmaceutical company to determine how much to allocate for research and development of drugs, the amount of each drug to manufacture, or …

Diagnostic Checking, Time Series And Regression, Esam Mahdi

Electronic Thesis and Dissertation Repository

In this thesis, a new univariate-multivariate portmanteau test is derived. The proposed test statistic can be used for diagnostic checking ARMA, VAR, FGN, GARCH, and TAR time series models as well as for checking randomness of series and goodness-of- fit VAR models with stable Paretian errors. The asymptotic distribution of the test statistic is derived as well as a chi-square approximation. However, the Monte-Carlo test is recommended unless the series is very long. Extensive simulation experiments demonstrate the usefulness of this test and its improved power performance compared to widely used previous multivariate portmanteau diagnostic check. The contributed R package …

An Introduction To Bayesian Methodology Via Winbugs And Proc Mcmc, Heidi Lula Lindsey

Theses and Dissertations

Bayesian statistical methods have long been computationally out of reach because the analysis often requires integration of high-dimensional functions. Recent advancements in computational tools to apply Markov Chain Monte Carlo (MCMC) methods are making Bayesian data analysis accessible for all statisticians. Two such computer tools are Win-BUGS and SASR 9.2's PROC MCMC. Bayesian methodology will be introduced through discussion of fourteen statistical examples with code and computer output to demonstrate the power of these computational tools in a wide variety of settings.

Assessing The Effect Of Wal-Mart In Rural Utah Areas, Angela Nelson

Theses and Dissertations

Walmart and other “big box” stores seek to expand in rural markets, possibly due to cheap land and lack of zoning laws. In August 2000, Walmart opened a store in Ephraim, a small rural town in central Utah. It is of interest to understand how Walmart's entrance into the local market changes the sales tax revenue base for Ephraim and for the surrounding municipalities. It is thought that small “Mom and Pop” stores go out of business because they cannot compete with Walmart's prices, leading to a decrease in variety, selection, convenience, and most importantly, sales tax revenue base in …

Hierarchical Probit Models For Ordinal Ratings Data, Allison M. Butler

Theses and Dissertations

University students often complete evaluations of their courses and instructors. The evaluation tool typically contains questions about the course and the instructor on an ordinal Likert scale. We assess instructor effectiveness while adjusting for known confounders. We present a probit regression model with a latent variable to measure the instructor effectiveness accounting for student specific covariates, such as student grade in the course, high school and university GPA, and ACT score.

Music And Radio Preferences On The Cal Poly Campus, Rory Bloch

Statistics

No abstract provided.

Using Survival Analysis Methods To Study Santa Barbara County Divorces, Joel Vazquez

Statistics

No abstract provided.

Dietary Patterns In Relation To Sleep And Stress In Cal Poly Freshman, Emily J. Conklin, Jongyoon Lee

Statistics

The Cal Poly FLASH study is a research project that was developed to assess overall health of college students. Beginning in Fall 2009, data have been collected longitudinally via online surveys and physical assessments on Cal Poly freshmen. Responses from 1520 students from Fall 2009 were used to investigate whether stress and sleeping habits are related to dietary patterns among Cal Poly students.

Factor analysis was used to categorize 33 food frequency variables into two categories – junk food and healthy food. Then, stepwise selection in a general linear model was conducted to identify lifestyle and demographic variables associated with …

An Exploration Of Non-Detects In Environmental Data, Juliana Fajardo

Statistics

No abstract provided.

Analysis Of Roms Estimated Posterior Error Utilizing 4dvar Data Assimilation, Joseph Patrick Horton

Mathematics

The appropriateness of the approximate error calculated by the Regional Ocean Modeling System (ROMS) is analyzed using Four-Dimensional Data Assimilation (4DVAR) performed on a numerical model of the San Luis Obispo Bay. An effective method of sampling data to minimize the actual error associated with the assimilated numerical model is explored by using different data sampling methods. An idealized state of the SLO bay region ("Real Run") is created to be used as the real ocean, then a numerical model of this region is created approximating this Real Run; this is known as the "Simulated State". By taking samples from …

Analysis Of The 2008 Flare Of Markarian 421 Flare With Veritas, Casey Allard

Physics

A theoretical light curve model is fit to an observed short term flare of Markarian (Mrk) 421 in the very high energy spectrum. The flare is characterized by its measured light curve from the Very Energetic Radiation Imaging telescope Array System (VERITAS). The flare we analyzed occurred in May 2008. We successfully fit a theoretical model to the Mrk 421 data light curve. The data appears to agree with the Wagner [1] and Salvati [2] models. These models appear to fit both broad and sharp flaring regions found in the measured light curve. Furthermore the Wagner model is used to …

Relationship Of Vitamin D Levels To Blood Pressure In A Biethnic Cohort, Rosario O. Sakamoto

Loma Linda University Electronic Theses, Dissertations & Projects

Background: Serum hydroxyvitamin D [25(OH)D] has been well-accepted as not an ordinary vitamin but a pro-hormone that has many benefits beyond its well-known effects on bone. Cardiovascular risk factors such as hypertension remain a huge health burden and Blacks have been recognized to have higher prevalence of hypertension compared to non-Hispanic Whites. Despite increasing evidence of the benefits of vitamin D on blood pressure control, there is much more to be learned about the relationship of serum 25(OH)D to blood pressure among different ethnicities.

Purpose: The goal of this study was to determine whether vitamin D serum 25(OH)D levels were …

A Bayesian Approach To Missile Reliability, Taylor Hardison Redd

Theses and Dissertations

Each year, billions of dollars are spent on missiles and munitions by the United States government. It is therefore vital to have a dependable method to estimate the reliability of these missiles. It is important to take into account the age of the missile, the reliability of different components of the missile, and the impact of different launch phases on missile reliability. Additionally, it is of importance to estimate the missile performance under a variety of test conditions, or modalities. Bayesian logistic regression is utilized to accurately make these estimates. This project presents both previously proposed methods and ways to …

Ranking Single Nucleotide Polymorphisms With Support Vector Regression In Continuous Phenotypes, Seif Shahidain

Theses

Support vector machines (SVM) have been used to improve the ranking of single nucleotide polymorphisms (SNPs) over traditional chi-square tests in disease case studies [2]. In this investigation, ranking SNPs with support vector regression (SVR) was compared to the Wald test in predicting continuous phenotypes. SVR-ranked SNPs consistently outperformed the Wald test-ranked SNPs to provide a more accurate prediction of the phenotype with fewer SNPs across several methods of prediction.

Adaptive Threat Detector Testing Using Bayesian Gaussian Process Models, Bradley Thomas Ferguson

Theses and Dissertations

Detection of biological and chemical threats is an important consideration in the modern national defense policy. Much of the testing and evaluation of threat detection technologies is performed without appropriate uncertainty quantification. This paper proposes an approach to analyzing the effect of threat concentration on the probability of detecting chemical and biological threats. The approach uses a probit semi-parametric formulation between threat concentration level and the probability of instrument detection. It also utilizes a bayesian adaptive design to determine at which threat concentrations the tests should be performed. The approach offers unique advantages, namely, the flexibility to model non-monotone curves …

The Quantum Dialectic, Logan Kelley

Pitzer Senior Theses

A philosophic account of quantum physics. The thesis is divided into two parts. Part I is dedicated to laying the groundwork of quantum physics, and explaining some of the primary difficulties. Subjects of interest will include the principle of locality, the quantum uncertainty principle, and Einstein's criterion for reality. Quantum dilemmas discussed include the double-slit experiment, observations of spin and polarization, EPR, and Bell's theorem. The first part will argue that mathematical-physical descriptions of the world fall short of explaining the experimental observations of quantum phenomenon. The problem, as will be argued, is framework of the physical descriptive schema. Part …

Solving The Differential Equation For The Probit Function Using A Variant Of The Carleman Embedding Technique., Kelechukwu Iroajanma Alu

Electronic Theses and Dissertations

The probit function is the inverse of the cumulative distribution function associated with the standard normal distribution. It is of great utility in statistical modelling. The Carleman embedding technique has been shown to be effective in solving first order and, less efficiently, second order nonlinear differential equations. In this thesis, we show that solutions to the second order nonlinear differential equation for the probit function can be approximated efficiently using a variant of the Carleman embedding technique.

Power Analysis For Alternative Tests For The Equality Of Means., Haiyin Li

Electronic Theses and Dissertations

The two sample t-test is the test usually taught in introductory statistics courses to test for the equality of means of two populations. However, the t-test is not the only test available to compare the means of two populations. The randomization test is being incorporated into some introductory courses. There is also the bootstrap test. It is also not uncommon to decide the equality of the means based on confidence intervals for the means of these two populations. Are all those methods equally powerful? Can the idea of non-overlapping t confidence intervals be extended to bootstrap confidence intervals? The powers …

Use Of Remote Sensing, Hydrologic Tree-Ring Reconstructions, And Forecasting For Improved Water Resources Planning And Management, Cody Lee Moser

Doctoral Dissertations

Uncertainties were analyzed in three areas (remote sensing, dendroclimatology, and climate modeling) relevant to current water resources management. First, the research investigated the relationships between remotely sensed and in situ Snow Water Equivalent (SWE) datasets in three western U.S. basins. Agreement between SWE products was found to increase in lower elevation areas and later in the snowpack season. Principal Components Analysis (PCA) revealed two distinct snow regions among the datasets and Singular Value Decomposition (SVD) was used to link both data products with regional streamflow. Remotely sensed SWE was found to be sufficient to use in statistically based forecast models …