Physical Sciences and Mathematics Commons^™

An Investigation Of Some Changes In The Chemical Composition Of Arterial Tissue Which Correlate With The Development Of Arteriosclerosis, Richard Dee Strickland

Chemistry and Chemical Biology ETDs

Arteriosclerosis is one of the major health problems confronting people of middle and advanced age. The disorder, commonly called "hardening of the arteries", is a contributing factor in more deaths than any other ailment.

The profound alteration in the physical properties of arteries which comes about as a result of the sclerotic process suggests that equally important changes may take place in the chemical composition of the arterial tissue.

Studies In The Cinnoline Series, David B. Cox

Chemistry and Chemical Biology ETDs

Recent work by Castle and Kruse (16) has partially elucidated the range of reactivity of the chlorine atom in the compounds 4-chlorocinnoline and 4-chloro-6,7-dimethoxycinnoline. Condensations between the chlorinated cinnolines and certain phenylacetonitriles were found to proceed readily; however, condensations with compounds of the malonic ester type were unsuccessful. It was found that hydrolysis of the condensation product obtained from 4-chlorocinnoline and phenylacetontrile by hot 60% sulfuric acid caused decarboxylation of the intermediate acid, the final product being 4-benzylcinnoline. This compound has a formal resemblance to the basic ring structure of papaverine.

Chelation Of The Rare Earth Elements As A Function Of Ph Using Thenoyltrifluoroacetone, Hugh James Bronaugh

Chemistry and Chemical Biology ETDs

The rare Earth elements, or lanthanides, having atomic numbers 57 through 71 occupy only one space in the periodic chart of the elements. These fifteen elements, which have extraordinarily similar chemical and physical properties, are placed in group three of the periodic table, between barium of group two and hafnium of group four. This series of elements has been the subject of extensive study in the past. The development of atomic energy has significantly increased the interest in the rare earths in the past ten years.

A Study Of The Kinetics And The Free Radicals Involved In The Low-Pressure, Vapor-Phase Pyrolysis Of Toluene, Robert E. Williams

Chemistry and Chemical Biology ETDs

This research was undertaken to study the pyrolysis of toluene in the vapor phase.

Many pyrolytic reactions of toluene have been studied by others, but the difficulty of controlling the reactions and the complexity of the products have not allowed much successful application of the results. The present work was an endeavor to better understand the reaction mechanisms and the intermediates involved in pyrolysis.

Specifically, the problem was to study the discrepancies between the results reported by M. Szwarc and by Hein and Mesee.

The Separation Of Antimony 125 From Solutions Of Neutron Irradiated Tin Salts, Joseph D. Robinson

Chemistry and Chemical Biology ETDs

Because of the importance of high specific activities of radioactive species considerable experimental work has been done on the preparation of "carrier-free" tracers. In surveying the literature on the preparation of carrier-free antimony only one method was found. The method reported involves the deuteron bombardment of tin; solution of the target in agua regia; addition of cadmium carrier; precipitation of the cadmium as the sulfide which carries antimony, using oxalate ion to complex the tin; solution to the sulfides of cadmium and antimony in concentrated hydrochloric acid; distillation of tin from cadmium and antimony contained in in perchloric acid with …

Polargraphic Measurement Of Reaction Rates Of Diazonium Salts, Gregory W. Daues

Chemistry and Chemical Biology ETDs

If a colorimetric method is used for following the reactions by tracing the increase in dye concentration, only reactions which form soluble dyes can be studied. Gasometric techniques are limited in that a sample must be removed from the reaction vessel and the diazonium salt decomposed by means of a catalyst in order to measure the liberated nitrogen. The latter method of analysis lends itself more readily to studies of the rate of decomposition of diazonium salts under various conditions, such as, the presence of ultra-violet light or exposure to high temperatures.

The Kinetics Of The Exchange Between Diiodotyrosine And Iodine, Alfred H. Zeltzmann

Chemistry and Chemical Biology ETDs

The rate of exchange of iodine with diiodotyrosine in squamous solution was studied as a function of the concentrations of both reactants, of the pH, and of the temperature. The concentration of diiodotyrosine was varied from 0.0000475 to 0.01251 moles per liter and that of the iodine from 0.0000103 to 0.000395 moles per liter. The upper limits of concentration studied were determined by the solubilities of both the iodine and diiodotyrosine. The ratio of concentration of diiodotyrosine to that of iodine was varied from 227 to 0.5. the temperature was varied from 25.1 degrees C to 42.1 degrees C, and …

A Study Of The Exchange Between P-Nitrobenzyl Iodide And Iodide Ion In Alcoholic Solutions., E. Lee Purlee

Chemistry and Chemical Biology ETDs

The realm of this study embraces observation of the exchange of iodine and potassium iodide in absolute methanol, absolute ethanol and absolute n-propanol at temperatures of 30.9 °, 20.3 ° and 0.0 ° centigrade. The primary aims were to observe the effects of the p-nitro group upon the exchange rates in effects of the p-nitro group upon the exchange rates in the various solvents and to compare the results with those obtained for the benzyl iodide-iodide exchange.

Enrichment Of Tin Activity Through The Szilard-Chalmers Separation, Herta W. Spano

Chemistry and Chemical Biology ETDs

It was the purpose of this investigation to utilize the Szilard-Chalmers reaction in order to prepare tin solutions of high specific activity.

Tetraphenyl tin was chosen for the target compound. It is a white, crystalline solid of excellent thermal stability. No data have been reported in the literature on the rate of exchange between inorganic forms of tin and tetraphenyl tin but it seemed highly probable that this exchange would be very slow. Tetraphenyl tin is soluble in various organic solvents but insoluble in water, and this suggested solvent extraction as a possible means of separation of the activated tin …

Derivatives Of M-Xylene, Henry J. Muller

Chemistry and Chemical Biology ETDs

Since m-xylene of 95-98% purity has recently become available from petroleum, this is an appropriate time to prepare an examine its derivatives. Isophtalic and m-toluic acids can be prepared from the hydrocarbon. The purpose of this work was to prepare imidazolines from these acids

The Chemical Characteristics Of 8.0-Day I^131 Produced By The Beta Decay Of 25-Minute Te^131 In Organic Liquids, Francis J. Keneshea Jr.

Chemistry and Chemical Biology ETDs

In 1934 Szilard and Chalmers found that a large fraction of the radioactive iodine produced in the thermal neutron irradiation of ethyl iodide could be extracted from the irradiated material. The procedure followed was to add a trace of carrier iodine to the irradiated liquid, extract the iodine with an aqueous solution of a reducing agent and precipitate the iodide as silver iodide. The silver iodide precipitate obtained in this manner contained a large fraction of the iodine activity (25-minute I¹²⁸), at a high specific activity. Since ethyl iodide is not soluble in water and hence is not …

The Kinetics Of The Exchange Between Benzyl Iodide And Iodide Ion, Paul Stillson

Chemistry and Chemical Biology ETDs

In the investigation to be described here, the exchange reaction was carried out in methyl alcohol, ethyl alcohol, and acetone-alcohol mixtures. Radioactive I¹³¹ was used as a tracer throughout the investigation. A mechanism was postulated for this reaction in each solvent and activation energies were determined.

The Kinetics Of The Exchange Between Sn(Ii) And Sn(Iv) In Absolute Alcohol, E. Gerald Meyer

Chemistry and Chemical Biology ETDs

In the present work use was made of the radiochemical exchange reaction to study the kinetics of the reaction

SnCl₂ + Sn*Cl₄ = Sn*Cl₂ + SnCl₄

in an absolute alcohol medium. A rate equation was established as a function of concentration and temperature, and some predictions were made regarding the mechanism.

Some Reactions Of 4-Chlorocinnoline, F. H. Kruse

Chemistry and Chemical Biology ETDs

This problem involves the preparation of 4-chlorocinnoline by the method of Borshe and Herbert and Busch and Rast,^, and the study of further replacement reactions of the chlorine atom in the 4-position. The problem can be subdivided into two sections: (1) the preparation of the 4-cinnolyl Grignard reagent and the corresponding lithium compound and (2) the study of some condensation reactions of 4-chlorocinnoline.

An Analytical Study Of Berberine, W. Riley Mcgaughran

Chemistry and Chemical Biology ETDs

Berberine, an alkaloid, has unique pharmacological properties as well as unusual chemical and physical characteristics. This compound has been used for many years as a remedy for eye diseases. In contrast to most alkaloids, berberine hydroxide is more soluble than its salts. Its chemical structure has been established, but a correlations of many of its properties and its structures has not been made.

The purpose of this work was to undertake an analytical study of berberine, hoping to collect data which would make possible the correlation of certain properties of the compound with its structure. The study was planned to …

A Study Of The Use Of The Dicyanatodipyridine (Ii) Complex For The Determination Of Cyanate, Jean Mcclelland

Chemistry and Chemical Biology ETDs

Treadwell states in his text, Analytical Chemistry, Volume II, that "the only method for examining cyanates consists in determining the amount of carbon and nitrogen present by combustion." A review of the available literature shows that, although this is not literally true, a procedure for this quantitative determination of small amounts of cyanates in the presence of interfering substances is lacking.

A survey of the literature yielded few references for instrumental methods for the quantitative determination of cyanates. Ripan-Tilici published a method for the determination of cyanates poteniometrically, but attempts to duplicate her work have failed. Madame Tilici, in …

The Syntheses And Ultraviolet Absorption Spectra Of 2-Imidazolines, 2-Imidazolidones And Imidazolidines, Robert J. Ferm

Chemistry and Chemical Biology ETDs

The first method used to prepare 2-imidazolines was through the reaction of aromatic aldehydes with ammonia. Amarin, which is known as 2,4,5-triphenyl-2-imidazoline, was the first compound reported to be prepared in this manner. This type of reaction has since been widely studied 2,3,4,5,6 in connection with the preparation of 2,4,5-triarylimidazolines. Furfural and ammonia have also been reported to react in a similar manner. Amarin has also been obtained from the reaction of a mixture of benzil, ammonia, and benzaldehyde.

The Preparation And Properties Of Aromatic Ditellurides, Roger Sanftner

Chemistry and Chemical Biology ETDs

All attempts to arrive at a conclusion as to the structure of the ditellurides by chemical means were unsuccessful. It was found that the ditelluride either failed to enter into reaction, or it reacted with the elimination of tellrium. It is thought, however, that a spectrophotometric analysis of the bromine addition would furnish some information concerning the ditelluride structure.

The Chelation Of Praseodymium As A Function Of Ph Using Thenolytrifluoroacetone, Thomas K. Keenan

Chemistry and Chemical Biology ETDs

The rare earth elements, including elements 57 through 71, provide many diverse series of studies through their chemical reactions. In as much as these elements are all in Group III of the periodic table, they are markedly similar in their properties. The separation, insulation and purification of the various rare earths from one another has long been a problem of great interest to the chemist.

A Study Of The Intermediary Products Formed During The Life Of A Copper Cyanide Plating Bath, Matthew E. Carlisle

Chemistry and Chemical Biology ETDs

Four aims of a study of cyanide baths were:

1. To study the intermediate products formed during the operation of plating and stripping baths under various conditions.

2. To identify these intermediate products or complexes and to determine whether or not they caused the failure of the bath.

3. To consider the conditions that caused a bath to fail, and to be able thereby to increase the life of the bath.

4. To develop a fast, accurate method for controlling the baths, preferably by means of the cyanide content.

The Use Of Ethyl 4,4-Dimethyl-1-Isopropyl-2-Imidazolinyl-2-Acetate In The Synthesis Of Some 2-Imidazolines, Jacob Shapira

Chemistry and Chemical Biology ETDs

One equivalent of N-(2-aminoisobutyl)-isopropyl-amine (I) was allowed to react with diethyl malonate to produce ethyl 4,4-dimethyl-1-isopropyl-2-imidazolinyl-2-acetate (II) in various yields which depended mainly on the temperature, time allowed for the reaction, and the method of isolation from the reaction mixture.

A Study Of Magnesium Silicate As A Base Matrix Material For Fluorescent Materials, John D. Hopperton

Chemistry and Chemical Biology ETDs

The purpose of the work herein described and discussed was to study the phosphor system built upon magnesium silicate as a base matrix material.

The particular phase of this study undertaken was a comprehensive survey of the activator materials, and an exhaustive study of one or two of these activator materials.

Synthesis Of Imidazolines, Diazepines, Triazepines And Imidazolidones From A 1, 2-Diamine And 1, 1-Dicarboxylic Esters., Irwin J. Pachter

Chemistry and Chemical Biology ETDs

In view of the inconclusive character of much of the above mentioned work, a further investigation of the reactions between 1, 2-diamines and dicarboxylic esters of the type CH3CH2OOCXCOOCH2CH3(X=CH2, CHR, NH) seemed warranted. In our present investigation we were guided by three main considerations.

Synthesis Of 2-Phenyl-2,1,3-Triazole-4-Carboxaldehyde And Some Derivatives, Gene Sumrell

Chemistry and Chemical Biology ETDs

It was decided in this problem to prepare 2-phenyl-2,1,3-triazole-4-carboxaldehyde (III) as a starting material by the method suggested by Hann and Hudson and run a number of typical aldehyde reactions with it. The preparation of (III) involved: (1) The hydrolysis of sucrose to form glucose and fructose; (2) conversion of these two sugars to D-glucose phenylosazone (I), by reaction with phenylhydrazine; (3) transformation of (I) to D-glucose phenylosotraizole (II), by the action of hot aqueous copper sulfate; and (4) oxidation of the side chain from (II) with sodium periodate, forming (III).

The reactions selected were: (1) the Grignard reaction; (2) …

The Conversion Of Certain Amino Acids To Carbohydrate In Normal Animals, Bergere Alfred Kenney

Chemistry and Chemical Biology ETDs

The glycogenic effects of the individual amino acids, in the metabolism of normal animals, are by no means well defined. IN some cases, as in those of alanine and glutamic acid, the tendency of the acid to form glucose is generally accepted; in others, of which leucine and lysine are good examples, there is definitely no glucose formation; in still other cases, namely those of glycine and cystine, the contradictory nature of the results obtained by different investigators gives anything but a clear picture of the situation...

It is the purpose of this paper, therefore, to attempt such an estimation …

A Chemical And Biological Study Of The Waters Of Elephant Butte Reservoir As Related To Fish Culture, John Greenbank

Chemistry and Chemical Biology ETDs

The purpose of this preliminary survey was to determine, in so far as was possible in the limited time that was available, the general suitability of the waters of the reservoir for fish life, and to make such recommendations for future fish culture policy as seemed to be advisable. AN unpublished report of this preliminary survey was written by Dr. Hazzard.

Public Water Supplies Of New Mexico, Kenneth F. Priest

Chemistry and Chemical Biology ETDs

Distribution of population in State. The estimated population for the State of New Mexico for the year 1930 was 423,300. A close observation of the population centers shows them to be scattered over a wide range of territory. The largest city, Albuquerque, has approximately 26,000 citizens. The next sites, according to the 1930 count, are three in number, Santa Fe, Roswell, and Clovis. The remaining population including rural districts do not number over eight thousand people.