Physical Sciences and Mathematics Commons^™

Therapeutic Outcomes Of Oral Antibiotics For The Treatment Of Methicillin-Resistant Staphylococcus Aureus Urinary Tract Infections: A Multisite, Retrospective Cohort Study Of Linezolid, Trimethoprim–Sulfamethoxazole And Doxycycline, Ryan Mccall, Elena Gatskevich, Steven E. Fiester, Michael Floren, Elisabeth Chandler

Chemistry Publications

Background: Methicillin-resistant Staphylococcus aureus (MRSA) urinary tract infections (UTIs), while relatively uncommon, pose a unique challenge in treatment as only specific intravenous (IV) options are typically utilized, with the efficacy of oral antimicrobials being poorly defined. Methods: The multi-site retrospective cohort study described herein therefore aims to characterize outcomes associated with oral administration of linezolid, trimethoprim-sulfamethoxazole (TMP-SMX), or doxycycline for the treatment of MRSA UTIs. Study participants were adults with culture-positive MRSA UTIs receiving one of the three oral therapies. Exclusion criteria included polymicrobial UTI, concomitant MRSA outside the urinary tract, receipt of non-study anti-MRSA agents for greater than or …

2026 Final Bpsou Backfill And Cover Material Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Complementary Thermodynamic Mechanisms Of Boron And Carbon Segregation At Grain Boundaries In Nickel Alloys, Tyler D. Dolezal, Rodrigo Freitas, Ju Li

Faculty Publications

Grain boundary stabilization by light interstitials is central to the performance of Ni-based superalloys, yet the thermodynamic mechanisms governing their interactions with substitutional chemistry remain poorly resolved. Here, we use hybrid Monte Carlo molecular dynamics simulations to quantify how boron and carbon modify the thermodynamic, structural, and chemical ordering of grain boundaries in Ni-Cr alloys. By analyzing interfacial state variables, site-resolved segregation spectra, local chemical ordering, and structural evolution, we show that boron and carbon stabilize grain boundaries through complementary pathways. Carbon drives saturation-controlled stabilization by recruiting Cr and conditioning boundary chemistry, while suppressing temperature-driven structural transformations of the boundary. …

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 57 – Little Mina-1, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 180 – Tullamore Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 75 – National Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 160s – Syndicate Pit Dumps, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

A Systematic Approach For Controlling Tem Sample Thicknesses, Monte Kozell

Physics Faculty Publications and Presentations

Historically, TEM prep has been an artisan craft without a systematic workflow that ensures quantified control over TEM sample thickness. Over- and under-thinning is a significant problem in the TEM prep process. A direct measurement process was demonstrated to control the final thickness of the TEM lamella. Final lamella thickness was controlled by directly measuring lamella thickness in real time using a 10–15 kV SEM while performing secondary electron imaging at the mill position, allowing for (human-mediated) closed-loop processing. We demonstrated the utility of this technique by systematically thinning five TEM samples to discretely target thicknesses ranging from 100 nm …

Epidemic Dynamics Under Pulse Population Exchange, Hannah Kravitz, Christina Durón, Moysey Brio

Mathematics and Statistics Faculty Publications and Presentations

Many epidemiological models assume either closed populations or continuous demographic turnover. We consider an intermediate setting in which exchange occurs through discrete pulses. In this paper, we introduce a population-conserving compartmental epidemiological model with pulse population exchange at a set of prescribed times. At each pulse, a fraction of the population in each compartment is replaced by a combination of susceptible and immunized individuals. In contrast to typical pulse birth or pulse vaccination models where only a single compartment undergoes a pulse population change, the pulses in this model have competing effects: removing infectious individuals reduces the force of infection, …

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 68 – Little Mina-2, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Implementation Of The Trojan Sex Chromosome Approach In The San Juan River: Investigation And Validation Of Feminization Methods For Channel Catfish, Chad Teal

Funded Research Records

No abstract provided.

2026 September 24 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 171 – Blaine Center, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Butte Priority Soils Operable Unit Final Reclamation Improvement Field Sampling And Investigation Plan: Bres No. 9 – Clark Street Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

An Ion-Neutral Reaction To Form Cyanobenzene And Ethynylbenzene In Titan’S Atmosphere, Rachel M. Huchmala, Vincent J. Esposito

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The ion-neutral reaction between cyanoacetylene (HC₃N) and phenyl anion (C₆H₅^–) leads to the formation of cyanobenzene (C₆H₅CN) and the ethynyl anion (C₂H^–) via a submerged, exothermic pathway. Through a different mechanism, the same two reactants also form ethynylbenzene (C₆H₅C₂H) and CN^–. These new reactions can be a foundation for the production of substituted benzenes using molecules currently present on Saturn’s largest moon, Titan. Cyclic aromatic molecules like C₆H₅CN and C₆H_{5 …}

Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou) 2025 Surface Water Compliance Evaluation Technical Memorandum (Dated June 29, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

From Scrolls To Algorithms: A Critical Analysis Of Generative Ai, Digital Preservation, And Ranganathan’S Normative Philosophy, Madhu K S

Book Chapters

The paper discusses the developments in human information access across three historical paradigms including physical scarcity, digital abundance, and synthetic algorithmic mediation with Generative AI. History is discussed with the philosophical aspects of Floridi’s Philosophy of Information, Christine Borgman’s Digital Scholarship Framework, and S R Ranganathan’s Normative Library Science. This conceptual paper explores the transition from finding documents to creating answers with AI it has changed human thinking and reliability on information. This transition has changed how people believe and trust the source of information. This paper looks at the material ethics regarding how commercial large language models (LLM) are …

A Deep Learning-Based Approach For Mapping Shrubs In Arctic Tundra From Very High-Resolution Imagery, Darko Radakovic, Mark Chopping, Bruce Cook, Aparna S. Varde, Stefan A. Robila

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Arctic shrub expansion is accelerating due to climate warming, but accurately mapping it at fine spatial scales remains challenging due to spectral overlap between shrubs and surrounding vegetation, heterogeneous tundra landscapes, and limited availability of very high-resolution imagery. This study presents a novel mapping and validation approach that integrates very high-resolution (< 1 m) QuickBird (QB) and WorldView (WV) satellite imagery across 12 North Slope sites, using deep learning architectures to map changes in shrub cover from 2002 to 2022. Deep learning models, including Convolutional Neural Network (CNN), ResNet, VGG, U-Net, and Vision Transformer, were trained on 4,100 3-channel pansharpened multispectral images (200×200 m). Two traditional machine learning models (Random Forest and Support Vector Machine) served as a control group. Leave-one-site-out cross-validation showed that all models performed well (AUC-ROC of 0.78–0.86, F1 at validation of 0.33-0.46) and had a moderate to strong agreement with field reference data (R2 = 0.76–0.87). The pretrained VGG and ResNet models achieved the strongest field-reference alignments for shrub cover prediction, while the difference with traditional models was small. Temporal trend analyses for July and August demonstrate a cover change of 0.06–0.45% yr-1 with unweighted mean area slopes and 0.01–0.92% yr-1 inverse-variance weighting. Growth rates were found to depend on the analytical design. Furthermore, the limiting factor in mapping shrub cover was not model complexity but the quality of the training data labels (annotation method explained ∼26% of the error variance). Per-scene cover error was seen across architectures (ρ = 0.67). Comparison with NASA Goddard's LiDAR, Hyperspectral and Thermal (G-LiHT)-derived Canopy Height Models revealed a weak-to-moderate relationship (R2 = 0.04–0.77), suggesting horizontal cover and vertical canopy structure capture complementary aspects of shrub abundance. These results demonstrate the potential of deep learning to map decadal shrub expansion at sub-meter resolution.

K 1-6 Is A Photoionised Interstellar Medium Nebula Shaped By A Fast-Moving Hot White Dwarf In A Triple System, Jaroslav Merc, David Jones, Ana Escorza, Henri M. J. Boffin, Nicole Reindl, Michael Abdul-Masih, Thomas Masseron, Paulina Sowicka, Jan Kára, Jorge Jorge García-Rojas

Physics & Astronomy Faculty Publications

Aims. K 1-6 has long been classified as a planetary nebula (PN) hosting a binary central star; however, it has remained poorly studied due to its faintness. The central star exhibits pronounced photometric variability whose origin is still unclear. We present a comprehensive characterisation of the K 1-6 system, including the physical properties of its stellar components and the nature of the surrounding nebulosity.

Methods. We conducted a multi-wavelength analysis combining optical and UV spectroscopy obtained with the Gran Telescopio Canarias, the Telescopio Nazionale Galileo, the Nordic Optical Telescope, and the Hubble Space Telescope. We also present long-term multi-band ground- …

How Far Do A Smile And A Hand Held Tight Reach? Children’S Play As A Transdisciplinary Predictor Of The Trajectory Of Physicochemical Processes On Atomic, Molecular And Cellular Scales, Evangelina Wu Uskoković, Theo Wu Uskoković, Vuk Uskoković

Administration and Staff Articles and Research

The search for an intrinsically beautiful scientific project took two children and their parent to over 600 visits of 181 playgrounds scattered throughout northern, central and southern California over the period of more than three years. Their goal was to test the hypothesis that children’s happiness and fondness for communication at playgrounds could be used, through complexity and entropy as intermediary quantities, as predictors of the evolution of physical, chemical and biological phenomena on microscopic scales ranging from the atomic to the cellular. Specifically, a link was sought between the children’s responses at play and the reaction paths of physicochemical …

Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou) Draft 2025 Site-Wide Surface Water Monitoring Data Summary Report (Dated May 29, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Final 2026 Interim Site-Wide Groundwater Monitoring Quality Assurance Project Plan (Dated August 28, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Final 2026 Interim Site- Wide Surface Water Monitoring Quality Assurance Project Plan (Qapp) (Dated August 28, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Fully Anharmonic Infrared Spectra Of Neutral Polycyclic Aromatic Hydrocarbons With Up To 38 Carbons, Nolan J. H. White, Vincent J. Esposito, Christiaan Boersma, Louis J. Allamandola, Jesse D. Bregman, Alexandros Maragkoudakis, Pasquale Temi, Ryan Fortenberry

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Interstellar aromatic infrared band (AIB) spectra show agreement with presently computed anharmonic spectra for various types of polycyclic aromatic hydrocarbons (PAHs) determined using a novel semiempirical quantum chemical method. Since the AIB spectrum is a blend of emission spectra from a vast number of different PAHs, likely with an array of different molecular structures, the spectra for a sample set of 31 PAHs ranging in size from naphthalene (C₁₀H₈) up to circumbiphenyl (C₃₈H₁₆) are combined, giving consideration to almost all PAH structural motifs. The computed numerical quartic force fields coupled to second-order …

Predicting Oncogenic Mutants Of Epidermal Growth Factor Receptor In Lung Cancer By Molecular Dynamics Simulation With Machine Learning, Victor O. Anyanwu, Justin Spiriti, Chung Wong

Chemistry & Biochemistry Faculty Works

The epidermal growth factor receptor (EGFR) is a frequently mutated protein kinase found in patients suffering from non-small cell lung cancer (NSCLC). Although therapeutic drugs targeting EGFR are available, not all patients respond to these drugs, and it is not yet known whether some clinically detected mutations are actionable. Although the oncogenicity of some mutants is well established, many mutants found in patients are not yet classified or classified as Variants of Uncertain Significance. For newly discovered rare mutants, strong evidence supporting their classification into oncogenic or benign is often lacking. Under such situations, multiple pieces of evidence can still …

A Unified Sensitivity Kernel For Coherent Wave Tomography In Radar, Seismic, Ultrasound And Optical Imaging, Alexey Yamilov

Research Data

Overview:

Six figures of the manuscript that report numerical simulations, main-text Fig. 5 and Supplementary Figs. S3 to S7, each as a PDF together with the plotted data in one CSV file per figure. The simulations are described in the Methods and in Supplementary Note S10 of the manuscript (arXiv:2609.31583). They were computed with MESTI in two dimensions and with the modified Born series in three, on the Mill and Hellbender clusters. The README describes the files and the layout of the CSV files.

Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou) Draft 2025 Groundwater Monitoring Data Summary Report January – December 2025 (Dated May 29, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Simultaneous Analysis Of Phytohormones And Lipid Peroxidation Products In Plant Seeds By Lc-Ms/Ms After Molecular Weight Cutoff Filtration, Sargun Kaur, Honglan Shi, Obed Patty, Paul Ki-Souk Nam

Chemistry Faculty Research & Creative Works

Investigation of the phytohormone and lipid peroxidation product levels in plant seeds can provide an insight into their germination potential and vigor. Simultaneous analysis of these diverse classes of compounds presents a significant challenge for a sample preparation method tailored to accommodate their distinct chemical properties. In this study, an analytical method consisting of simple extraction, molecular weight cutoff filtration, and subsequent liquid-chromatography tandem mass spectrometry (LC-MS/MS) analysis was developed for accurate quantification of 11 phytohormones including 2 auxins, 4 cytokinins, 2 gibberellins, abscisic acid, salicylic acid, and jasmonic acid in plant seeds. Additionally, the new method was used for …

Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou) Butte Reduction Works Smelter Area Intermediate 60% Remedial Design Submittal (Dated May 19, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Infrared Spectroscopy And Photochemistry Of Aromatic Nitriles In Para-Hydrogen Matrices, Sam Mcgrath, Vincent J. Esposito, Linshan Zeng, Thomas H. Speak, Brendan Moore, Pavle Djuricanin, Jun Miyazaki, Takamasa Momose, Ilsa R. Cooke

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Motivated by recent detections of several aromatic nitriles in Taurus Molecular Cloud 1, we report laboratory and theoretical investigations of the vibrational spectroscopy and photochemistry of singly and doubly cyanosubstituted benzene in solid para-hydrogen matrices. We compare the photochemistry of cyanobenzene (benzonitrile) and three dicyanobenzene isomers initiated by excitations at 193 nm. In addition, we report the photochemistry of deuterated cyanobenzene (d5-cyanobenzene), enabling us to determine the major products produced during the cyanobenzene photodissociation. The major products observed in the photolysis of all the nitriles are HCN and HNC, which are likely produced by hydrogen abstraction from para-hydrogen by the …