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Voltammetric Determination Of Glycopyrrolate In A Pharmaceutical Formulation, Muneer Fadr, Abdulaziz Nabil Amro, Sami Ben Aoun, Samer Ratrout, Fadi Asfour Jan 2018

Voltammetric Determination Of Glycopyrrolate In A Pharmaceutical Formulation, Muneer Fadr, Abdulaziz Nabil Amro, Sami Ben Aoun, Samer Ratrout, Fadi Asfour

Turkish Journal of Chemistry

The electrochemical activity of glycopyrrolate was studied. Different voltammetric techniques were applied in this study, including cyclic voltammetry (CV), differential pulse voltammetry (DPV), and linear sweep voltammetry (LSV). Glassy carbon and platinum working electrodes were utilized. CV indicated that glycopyrrolate has a reversible redox reaction on the working electrode surface, with an anodic peak current at approximately 1.05 V and a cathodic peak at 0.80 V. Several parameters that affect the sensitivity of these methods were optimized for the quantitation of glycopyrrolate. LSV showed a better correlation coefficient than DPV did, with a value of ca. 0.9990 in the range …