Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- 1 (4)
- Adsorption (4)
- 2 (3)
- Nanocomposite (3)
- 3-triazoles (2)
-
- Anticancer activity (2)
- Antimicrobial activity (2)
- Benzimidazole (2)
- C6 (2)
- Chitosan (2)
- Cytotoxic activity (2)
- Cytotoxicity (2)
- Fluorescence (2)
- HeLa (2)
- Microextraction (2)
- Palladium (2)
- Phthalocyanine (2)
- Selectivity (2)
- Singlet oxygen (2)
- Synthesis (2)
- Ultrasound (2)
- $N$-carbamothioyl (1)
- $N$-substituted azole acrylates (1)
- $\beta $-amino alcohols (1)
- $\gamma $-Al$_{2}$O$_{3}$ (1)
- $h$MAO enzymes (1)
- 1-(2-pyridylazo)-2-naphthol (1)
- 2-nitrobenzaldehyde (1)
- 3-$c$]phenazine (1)
- 3-$d$]pyrimidine-6-carbonitrile (1)
Articles 31 - 60 of 80
Full-Text Articles in Physical Sciences and Mathematics
Palladium Nanoparticles Entrapped In Melamine-Formaldehyde Resin Microparticles For Mizoroki--Heck Reactions, Shaofeng Zhong
Palladium Nanoparticles Entrapped In Melamine-Formaldehyde Resin Microparticles For Mizoroki--Heck Reactions, Shaofeng Zhong
Turkish Journal of Chemistry
Melamine-formaldehyde resin (MFR) microparticles with average diameters of 1.06 $\mu $m were synthesized with PEG-20000 as the particle-forming agent. Palladium nanoparticles were entrapped in and adsorbed on the MFR microparticles, consecutively. Scanning electron microscopy (SEM) was used to characterize the morphologies of MFR microparticles. X-ray diffraction (XRD) and transition electron microscopy (TEM) showed that the palladium nanoparticles entrapped in the MFR microparticles dispersed much more homogeneously than those adsorbed on the MFR microparticles. Mizoroki--Heck reaction catalysis results demonstrated that the entrapped palladium catalyst had similar catalytic activity with the adsorbed palladium catalyst. Moreover, this novel entrapped palladium catalyst could be …
Understanding Of Phenolic Compound Retention Mechanisms On Pes-Uf Membrane, Amine Mnif, Meral Mouelhi, Bechir Hamrouni
Understanding Of Phenolic Compound Retention Mechanisms On Pes-Uf Membrane, Amine Mnif, Meral Mouelhi, Bechir Hamrouni
Turkish Journal of Chemistry
Ultrafiltration (UF) is investigated as a possible alternative to remove organic compounds from aqueous synthetic solution. This paper presents a comprehensive study towards a better understanding of phenolic compound retention mechanisms during UF processes. Thus, removal of phenol and resorcinol was studied using a polyethersulfone ultrafiltration (PES-UF) membrane. The influence of main operating conditions (feed concentration, transmembrane pressure, and pH) on the retention was evaluated. Membrane--solute interactions were found to play an important role during the process, suggesting the adsorption of the target compounds on the PES-UF membrane. The level of adsorption was consequently evaluated by measuring the quantity of …
Investigation Of Photochemical And Photophysical Properties Of Novel Silicon(Iv) Phthalocyanines And Their $\Mu $-Oxo Dimers, Ömer Güngör, Mahmut Durmuş, Vefa Ahsen
Investigation Of Photochemical And Photophysical Properties Of Novel Silicon(Iv) Phthalocyanines And Their $\Mu $-Oxo Dimers, Ömer Güngör, Mahmut Durmuş, Vefa Ahsen
Turkish Journal of Chemistry
The synthesis and characterization of novel tetraalkylthio (SC$_{6}$H$_{13}$ or SC$_{12}$H$_{25})$ substituted $\mu $-oxo silicon(IV) phthalocyanines (3a and 3b) and their $\mu$-oxo derivatives (4a and 4b) were described in this study. These silicon(IV) phthalocyanines were characterized using different spectroscopic techniques such as UV-Vis, $^{1}$H NMR, FT-IR, and mass and elemental analysis, as well. Furthermore, the photophysical (fluorescence quantum yields and lifetimes) and photochemical (singlet oxygen generation) properties of the newly synthesized silicon(IV) phthalocyanines (3a, 3b, 4a, and 4b) were investigated in dimethylformamide solution. The absorption and fluorescence excitation wavelengths of the studied silicon(IV) phthalocyanines were blue-shifted when they converted to their …
Synthesis Of Pds/Zns--Cds-Type Photocatalysts Using Zns As Sulphide Source, Radu Banica, Petrica Linul, Cristina Mosoarca
Synthesis Of Pds/Zns--Cds-Type Photocatalysts Using Zns As Sulphide Source, Radu Banica, Petrica Linul, Cristina Mosoarca
Turkish Journal of Chemistry
In this work, a new method for the growth of large CdS crystals into PdS/ZnS--CdS-type photocatalysts is presented. In order to accomplish this, in the first stage zinc sulphide was synthesised and hydrothermally crystallised. In the second stage, after PdS decoration, the recrystallised zinc sulphide was utilised as sulphur source for the synthesis of PdS/ZnS--CdS-type photocatalysts. The photocatalysts were characterised by X-ray diffraction, transmission electron microscopy, energy dispersive X-ray spectroscopy, and diffuse reflectance spectroscopy. In the third stage magnetic polymer supports were manufactured and loaded with photocatalyst. Finally photocatalysis experiments under blue light illumination were conducted for the hydrogen evolution …
Methanolysis Of Jatropha Curcas Oil Using K$_{2}$Co$_{3}$/Cao As A Solid Base Catalyst, Gajanan Sahu, Sujan Saha, Sudipta Datta, Prakash Chavan, Satyanarayan Naik
Methanolysis Of Jatropha Curcas Oil Using K$_{2}$Co$_{3}$/Cao As A Solid Base Catalyst, Gajanan Sahu, Sujan Saha, Sudipta Datta, Prakash Chavan, Satyanarayan Naik
Turkish Journal of Chemistry
Biodiesel, fatty acid methyl ester produced by the transesterification of vegetable oil with methanol, is a promising alternative to petroleum-based diesel fuel. In the present study, the methanolysis of high free fatty acid (FFA) $Jatropha$ $curcas$ oil in a transesterification reaction using K$_{2}$CO$_{3}$/CaO solid base catalyst was studied. The various reaction parameters in the transesterification reaction were also discussed. The catalyst was characterized by means of Fourier transform infrared, X-ray diffraction, temperature programmed desorption of CO$_{2}$, scanning electron microscopy, particle size analyzer, true density, and surface area analyzer. The optimum conversion of jatropha oil was 92% when the transesterification reaction …
Cyclic Voltammetry Behavior Of Tamoxifen In Different Electrolytes, Electrochemical Characterization, And Its Measurement By Differential Pulse Anodic Voltammetry, Zeinab Deris Falahieh, Mehdi Jalali, Mohammad Alimoradi
Cyclic Voltammetry Behavior Of Tamoxifen In Different Electrolytes, Electrochemical Characterization, And Its Measurement By Differential Pulse Anodic Voltammetry, Zeinab Deris Falahieh, Mehdi Jalali, Mohammad Alimoradi
Turkish Journal of Chemistry
Cyclic voltammetry (CV) was performed on tamoxifen (tam) using different electrodes and in various acidic electrolytes containing 10% v v$^{-1}$ methanol (MeOH). Tam oxidation was found to be most favorable using 0.1 mol L$^{-1}$ H$_{2}$SO$_{4}$. To investigate the mechanism, we performed chronoamperometry, CV at different scan rates, differential pulse anodic voltammetry (DPAV), and electrochemical impedance spectroscopy on tam-covered glassy carbon electrodes (GCEs). The electrode area, diffusion coefficient, and surface concentration ($\Gamma )$ of tam were calculated to be 0.062 cm$^{2}$, 3.65 $\times $ 10$^{-6}$ cm$^{2}$ s$^{-1}$, and 3.2 $\times $ 10$^{-10}$ mol cm$^{-2}$ respectively. Then the effects of different parameters …
Investigation Of Photoinduced Polymerization Of Doxycycline-Imprinted Hydrogels: Effect Of Template On Initiator Reactivity, Conversion, And Reaction Rate, Di̇lek Dalgakiran, Tuğçe İnan, Fatma Seni̇ha Güner
Investigation Of Photoinduced Polymerization Of Doxycycline-Imprinted Hydrogels: Effect Of Template On Initiator Reactivity, Conversion, And Reaction Rate, Di̇lek Dalgakiran, Tuğçe İnan, Fatma Seni̇ha Güner
Turkish Journal of Chemistry
Photopolymerization kinetics of doxycycline hyclate (DOX)-imprinted hydrogels were monitored by real-time Fourier transform infrared spectroscopy and differential photocalorimetry. 2-Hydroxyethyl methacrylate-based hydrogels were synthesized by using ethylene glycol dimethacrylate as a cross-linker, acrylic acid (AA) as a functional monomer, and 2,2-dimethyl-2-hydroxy acetophenone as a photoinitiator. For imprinting DOX in hydrogels, the molar ratio of template to functional monomer (DOX:AA) was chosen as 1:8 and 1:16. The polymerization was achieved at two different initiator concentrations. The conversion and reaction rate were calculated as a function of the molar ratio of template, and the results were compared to those of nonimprinted ones. In …
Separation And Recovery Of Gallium(Iii) Ions From Aqueous Phase By Liquid--Liquid Extraction Using A Novel Extractant, Cyphos Il 101, Sumitra Nayak, Niharbala Devi
Separation And Recovery Of Gallium(Iii) Ions From Aqueous Phase By Liquid--Liquid Extraction Using A Novel Extractant, Cyphos Il 101, Sumitra Nayak, Niharbala Devi
Turkish Journal of Chemistry
The present study describes the extraction behavior of gallium(III) using a novel ionic liquid trihexyl(tetradecyl) phosphonium chloride (Cyphos IL 101) diluted with kerosene from acidic chloride medium. The extraction of gallium was found to depend on the hydrochloric acid concentration and quantitative extraction of gallium took place at 2.0 mol/L HCl concentration. The nature of the extracted complex in the organic phase was determined using Job's method and proposed to be [R$_{3}$R$^\prime $PGaCl$_{4}$]. The loading capacity of 5.0 $\times$ 10$^{-3}$ mol/L Cyphos IL 101 was determined to be 320.0 mg/L. Two stages of stripping were required for complete removal of …
Naked Eye And Smartphone Applicable Detection Of Toxic Mercury Ions Using Fluorescent Carbon Nanodots, Burcu Baç, Rükan Genç
Naked Eye And Smartphone Applicable Detection Of Toxic Mercury Ions Using Fluorescent Carbon Nanodots, Burcu Baç, Rükan Genç
Turkish Journal of Chemistry
Chitosan passivated carbon nanodots (C-Dots$_{CHIT})$ were synthesized from expired molasses via a simple and green thermal synthesis procedure. As-synthesized C-Dots were nitrogen-doped (NC-Dots$_{CHIT})$ by posttreatment with liquid ammonia and used as nanoprobes for fluorometric detection of mercury ions (Hg(II)$_{aq.})$. Fluorescence response of NC-Dots$_{CHIT}$ in the presence of mercury was evaluated and compared with that of the polyethylene glycol passivated C-Dots$_{PEG}$. This sensing strategy using NC-Dots$_{CHIT}$ displayed a wide linear working range from 1.25 $\mu $g/mL to 43.54 $\mu $g/mL with a detection limit of 1.41 $\mu $g/mL. The fluorescence of C-Dots$_{PEG}$ did not show any significant change upon mercury addition. …
Ultrasound-Assisted Surfactant/Ionic Liquid Aqueous Two-Phase System Extraction Prior To High Performance Liquid Chromatography For The Determination Of Tetracyclines In Milk And Honey Samples, Hayri̇ye Mi̇ne Antep, Taşkin Mumcu, Kami̇l Bostanci, Serap Seyhan Bozkurt, Melek Merdi̇van
Ultrasound-Assisted Surfactant/Ionic Liquid Aqueous Two-Phase System Extraction Prior To High Performance Liquid Chromatography For The Determination Of Tetracyclines In Milk And Honey Samples, Hayri̇ye Mi̇ne Antep, Taşkin Mumcu, Kami̇l Bostanci, Serap Seyhan Bozkurt, Melek Merdi̇van
Turkish Journal of Chemistry
In this work, an ultrasonic-assisted surfactant/ionic liquid aqueous two-phase system (ATPS) extraction method was developed to extract six tetracycline antibiotics from food samples before their chromatographic determination using high performance liquid chromatography. The ATPS was formed with 1-allyl-3-methyl-imidazolium bromide, Triton X-100, and dipotassium hydrogen phosphate. The parameters including type and amount of surfactant, ionic liquid and salt, pH of sample solution, and sonication time were optimized. Under the optimized conditions, linear calibration curves of the six tetracyclines were obtained in the range of 10--500 $\mu $g L$^{-1}$ with $>$ r$^{2} =$ 0.990 (n $=$ 9). The proposed green analytical …
Electrochemical Detection Of Dna Interaction With Mannich Base Derivatives By Disposable Graphite Electrodes, Hüseyi̇n İstanbullu, Hakan Karadeni̇z, Erçi̇n Erci̇yas, Kadri̇ye Arzum Erdem Gürsan
Electrochemical Detection Of Dna Interaction With Mannich Base Derivatives By Disposable Graphite Electrodes, Hüseyi̇n İstanbullu, Hakan Karadeni̇z, Erçi̇n Erci̇yas, Kadri̇ye Arzum Erdem Gürsan
Turkish Journal of Chemistry
Four different Mannich base derivatives containing an aromatic/heteroaromatic propanone structure (C1 (3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride); C2 (3-morpholino-1-(pyridin-3-yl)propan-1-one hydrochloride); C3 (3-(dimethylamino)-1-(1H-indol-3-yl)propan-1-one hydrochloride), C4 (3-(piperidin-1-yl)-1-(pyren-1-yl)propan-1-one hydrochloride)) were earlier synthesized and characterized with $^{1}$H NMR, $^{13}$C NMR, MS, and elemental analysis. The interaction of these compounds with fish sperm double stranded DNA (fs-dsDNA) was investigated by using differential pulse voltammetry (DPV) in connection with a disposable pencil graphite electrode (PGE). After the interaction procedure, there was a meaningful decrease in the oxidation signal of the electroactive DNA base guanine due to possible intercalation and/or alkylation mechanism between these Mannich base derivatives and DNA. The features …
Investigation Of The Effects Of Purification And Characterization Of Turkey (Meleagris Gallopavo) Liver Mitochondrial Thioredoxin Reductase Enzyme And Some Metal Ions On Enzyme Activity, Yusuf Temel, Ö. İrfan Küfrevi̇oğlu, Mehmet Çi̇ftci̇
Investigation Of The Effects Of Purification And Characterization Of Turkey (Meleagris Gallopavo) Liver Mitochondrial Thioredoxin Reductase Enzyme And Some Metal Ions On Enzyme Activity, Yusuf Temel, Ö. İrfan Küfrevi̇oğlu, Mehmet Çi̇ftci̇
Turkish Journal of Chemistry
The thioredoxin system, found in all living creatures, consists of thioredoxin protein (Trx), thioredoxin reductase enzyme (TrxR), and NADPH. In this study, turkey liver mitochondrial TrxR enzyme with 3.07 EU $\times $ mg$^{-1}$ specific activity was purified 990-fold in a yield of 2.05{\%} using 2',5'-ADP Sepharose 4B affinity chromatography. The purity of the enzyme was measured and the molecular weight of its subunits was determined to be 45.5 kDa by SDS-PAGE. The molecular mass of the enzyme's natural state was found to be 88 kDa using Sephadex-G 150 gel filtration chromatography. In addition, characteristic and kinetic properties of the enzyme …
Supramolecular Solvent Microextraction Of Uranium At Trace Levels From Water And Soil Samples, Mansoor Khan, Erkan Yilmaz, Mustafa Soylak
Supramolecular Solvent Microextraction Of Uranium At Trace Levels From Water And Soil Samples, Mansoor Khan, Erkan Yilmaz, Mustafa Soylak
Turkish Journal of Chemistry
A supramolecular solvent microextraction procedure was established for the separation/preconcentration of uranium(VI) (U(VI)) prior to its determination by UV-Vis spectrophotometry. 1-(2-Pyridylazo)-2-naphthol (PAN) was used to form a red chelate (U-PAN) with U(VI) at pH 10. U-PAN was extracted by undecanol in tetrahydrofuran. All the parameters that affect extraction efficiency like solution pH, amount of ligand, type and volume of supramolecular solvent, sample volume, and diverse ion effect were optimized. The preconcentration factor was 17. The detection limit was 0.31 $\mu $g L$^{-1}$. The method was validated using GBW07424 (GSS-10 certified reference material). Microextraction was also applied to water and soil …
Voltammetric Analysis Of Disulfiram In Pharmaceuticals With A Cyclic Renewable Silver Amalgam Film Electrode, Sylwia Smarzewska, Natalia Festinger, Monika Skowron, Dariusz Guziejewski, Radovan Metelka, Mariola Brycht, Witold Ciesielski
Voltammetric Analysis Of Disulfiram In Pharmaceuticals With A Cyclic Renewable Silver Amalgam Film Electrode, Sylwia Smarzewska, Natalia Festinger, Monika Skowron, Dariusz Guziejewski, Radovan Metelka, Mariola Brycht, Witold Ciesielski
Turkish Journal of Chemistry
Electrochemical properties of disulfiram, representative of highly significant bioactive compounds, were studied with a cyclic renewable silver amalgam film electrode (Hg(Ag)FE) using square wave cathodic stripping voltammetry (SWCSV). The influence of various factors such as pH, buffer concentration, buffer composition, and SWCSV parameters on current response was investigated. The optimum results in terms of signal shape and intensity were recorded in Britton--Robinson buffer (pH 7.5) at -0.5 V versus Ag/AgCl/3 mol L$^{-1}$ KCl. An elaborated electroanalytical procedure was used to determine disulfiram at the Hg(Ag)FE in the concentration range from 0.05 to 5.00 $\mu $M. Precision, repeatability, and accuracy of …
Sonochemical Degradation Of Basic Red 29 In Aqueous Media, Zineb Boutamine, Slimane Merouani, Oualid Hamdaoui
Sonochemical Degradation Of Basic Red 29 In Aqueous Media, Zineb Boutamine, Slimane Merouani, Oualid Hamdaoui
Turkish Journal of Chemistry
In this work, the degradation of Basic Red 29 (BR29), an azo dye, was investigated using a high-frequency ultrasonic reactor (300 kHz). The influence of several parameters such as initial substrate concentration (5--200 mg L$^{-1})$, pH (3-10.1), ultrasonic power (20-80 W), and nature of the dissolved gas (Ar, air, and N$_{2})$ on the degradation of BR29 was assessed. Additionally, the impact of natural matrices (seawater and natural and river waters) on the degradation rate of BR29 was clarified. Degradation experiments with radical scavengers, tert-butyl alcohol and glucose, showed that BR29 degraded mainly through HO$^{\bullet }$ radical attack at the gas/liquid …
Synthesis And Cytotoxicity Of Novel Thioxo-Quinazolino[3,4-$A$]Quinazolinones, Negar Mohammadhosseini, Mina Saeedi, Shahram Moradi, Mohammad Mahdavi, Omidreza Firuzi, Alireza Foroumadi, Abbas Shafiee
Synthesis And Cytotoxicity Of Novel Thioxo-Quinazolino[3,4-$A$]Quinazolinones, Negar Mohammadhosseini, Mina Saeedi, Shahram Moradi, Mohammad Mahdavi, Omidreza Firuzi, Alireza Foroumadi, Abbas Shafiee
Turkish Journal of Chemistry
Various thioxo-quinazolino[3,4-$a$]quinazolinones were prepared and evaluated for their cytotoxicity in MOLT-4 (lymphoblastic leukemia) and MCF-7 (breast adenocarcinoma) cell lines. Synthesis of the target compounds was started from isatoic anhydride. Successive reaction of isatoic anhydride with benzylamine and 2-nitrobenzaldehyde, reduction of the nitro group, and reaction with CS$_{2}$ gave 12-benzyl-6-thioxo-6,7,11b,12-tetrahydro-13$H$-quinazolino[3,4-$a$]quinazolin-13-one. The latter compound reacted with various 2-chloro-$N$-substituted acetamides to afford the corresponding fused quinazolinone derivatives.
Synthesis And Characterization Of Magnetic Amidoximated Chitosan-G Poly(Polyacrylonitrile)/Laponite Rd Nanocomposites With Enhanced Adsorption Capacity For Cu$^{2+}$, Gholam Reza Mahdavinia, Ebrahim Shokri
Synthesis And Characterization Of Magnetic Amidoximated Chitosan-G Poly(Polyacrylonitrile)/Laponite Rd Nanocomposites With Enhanced Adsorption Capacity For Cu$^{2+}$, Gholam Reza Mahdavinia, Ebrahim Shokri
Turkish Journal of Chemistry
Magnetic amidoximated nanocomposites based on a combination of chitosan and magnetic laponite RD were prepared and examined for the removal of Cu$^{2+}$ from aqueous solutions. Magnetic laponite RD was prepared by an in situ method. In order to prepare magnetic amidoximated nanocomposites, acrylonitrile was grafted to chitosan in the presence of magnetic laponite RD. Then the nitrile pendants on magnetic chitosan-g-polyacrylonitrile/laponite RD (mChtioPANLap) were converted to amidoxime groups. We developed a polyamidoximated magnetic nanocomposite based on a mixture of chitosan/laponite RD, possessing a high adsorption capacity for Cu$^{2+}$. By introducing magnetic laponite RD the adsorption capacity of nanocomposites for Cu$^{2+}$ …
Synthesis And Antifungal Activity Of New Dihydrofurocoumarins And Dihydrofuroquinolines, Asli Ustalar, Mehmet Yilmaz, Agi̇m Osmani̇, Sema Aşkin Keçeli̇
Synthesis And Antifungal Activity Of New Dihydrofurocoumarins And Dihydrofuroquinolines, Asli Ustalar, Mehmet Yilmaz, Agi̇m Osmani̇, Sema Aşkin Keçeli̇
Turkish Journal of Chemistry
We investigated the radical addition of 4-hydroxycoumarin (1a) and 4-hydroxyquinoline (1b) with conjugated dienes ({2a-f) mediated by cerium(IV) ammonium nitrate (CAN) resulting in ethenyl substituted 2,3-dihydrofurocoumarin (3a-f) and 3,5-dihydrofuroquinoline (3g, 3h) compounds in moderate to good yields. All compounds were characterized by spectroscopic methods (IR, MS, and $^{1}$H and $^{13}$C NMR) and microanalysis. Antifungal activities of these compounds were investigated against the fungi Candida albicans, C. parapsilosis, C. krusei, C. glabrata, C. tropicalis, and Aspergillus fumigatus.
Isocoumarins And 3,4-Dihydroisocoumarins, Amazing Natural Products: A Review, Aisha Saddiqa, Osman Çakmak, Muhammad Usman
Isocoumarins And 3,4-Dihydroisocoumarins, Amazing Natural Products: A Review, Aisha Saddiqa, Osman Çakmak, Muhammad Usman
Turkish Journal of Chemistry
The isocoumarins are naturally occurring lactones that constitute an important class of natural products exhibiting an array of biological activities. A wide variety of these lactones have been isolated from natural sources and, due to their remarkable bioactivities and structural diversity, great attention has been focused on their synthesis. This review article focuses on their structural diversity, biological applications, and commonly used synthetic modes.
Synthesis And Anticancer And Cytotoxic Effects Of Novel 1,4-Phenylene-Bis-N-Thiocarbamoylpyrazole And 1,4-Phenylene-Bis-Pyrazolylthiazole Derivatives, Meli̇ha Burcu Gürdere, Erdoğan Kamo, Yakup Budak, Ayşe Şahi̇n Yağlioğlu, Mustafa Ceylan
Synthesis And Anticancer And Cytotoxic Effects Of Novel 1,4-Phenylene-Bis-N-Thiocarbamoylpyrazole And 1,4-Phenylene-Bis-Pyrazolylthiazole Derivatives, Meli̇ha Burcu Gürdere, Erdoğan Kamo, Yakup Budak, Ayşe Şahi̇n Yağlioğlu, Mustafa Ceylan
Turkish Journal of Chemistry
Thiazolylpyrazoline derivatives were recently reported as potent anticancer agents. In this study, novel 1,4-phenylene-bis-N-thiocarbamoylpyrazoles (3a-h and 1,4-phenylene-bis-pyrazolylthiazoles (5a-h were prepared and screened for their anticancer activities against C6 (rat brain tumor cells) and HeLa (human uterus carcinoma). Anticancer activity studies were performed as a dose-dependent assay starting with eight concentrations. 5-Fluorouracil (5-FU) was used as a positive control. Compounds 3c, 3d, and 3h were examined and they revealed almost the same activities compared with 5-FU in terms of cell selectivity against C6 cells. Moreover, compounds 3a-h had lower cytotoxicity than 5-FU. The low cytotoxicity values of 3a-h as well as …
Homopolymerization And Synthesis Of A New Methacrylate Monomer Bearing A Boron Side Group: Characterization And Determination Of Monomer Reactivity Ratios With Styrene, Tuba Çakir Çanak, Serkan Akpinar, İ. Ersi̇n Serhatli
Homopolymerization And Synthesis Of A New Methacrylate Monomer Bearing A Boron Side Group: Characterization And Determination Of Monomer Reactivity Ratios With Styrene, Tuba Çakir Çanak, Serkan Akpinar, İ. Ersi̇n Serhatli
Turkish Journal of Chemistry
Boron methacrylate (BAc) monomer was synthesized via an esterification reaction. Boric acid, neopentyl glycol, and 2-hydroxyethyl methacrylate (HEMA) were reacted to obtain boron-containing acrylic monomer. Characterization was achieved by FT-IR, $^{13}$C NMR, $^{1}$H NMR, and $^{11}$B NMR and the results for the synthesized monomer were compared to those for HEMA. Homopolymer and copolymers with styrene (St) were synthesized via free radical polymerization. The properties of the synthesized styrene copolymers were investigated using several techniques. Monomer reactivity ratios for the studied monomer pair were calculated using the extended Kelen-Tüdos method. Copolymerization compositions and reactive ratios showed that the obtained copolymers had …
A Biochar-Modified Carbon Paste Electrode, Derya Bal Altuntaş, Gökçen Akgül, Jale Yanik, Ülkü Anik
A Biochar-Modified Carbon Paste Electrode, Derya Bal Altuntaş, Gökçen Akgül, Jale Yanik, Ülkü Anik
Turkish Journal of Chemistry
The present work examıned the use of biochar derived from tea waste as a novel electrode material. For the fabrication of the biochar electrode, suitable amounts of biochar and graphite were mixed with mineral oil for the first time. The electrochemical performance of the biochar-modified carbon paste electrode (BCPE) was measured by various cyclic voltammetric reactions for several redox systems. The factors affecting the electrode kinetics of BCPE surfaces were examined and optimized. The BCPE was applied as transducer in a glucose biosensor. The results reflect the effective properties of composite electrodes and the electrochemical properties of biochar showing that …
Impact Of Surface Modification Of Green Algal Biomass By Phosphorylation On The Removal Of Copper(Ii) Ions From Water, Zakaria Al-Qodah, Mohammad Al-Shannag, Abdulaziz Amro, Eman Assirey, Mustafa Bob, Khalid Bani-Melhem, Malek Alkasrawi
Impact Of Surface Modification Of Green Algal Biomass By Phosphorylation On The Removal Of Copper(Ii) Ions From Water, Zakaria Al-Qodah, Mohammad Al-Shannag, Abdulaziz Amro, Eman Assirey, Mustafa Bob, Khalid Bani-Melhem, Malek Alkasrawi
Turkish Journal of Chemistry
A series of batch lab-scale experiments were performed to investigate the performance of dead phosphorylated algal biomass of Spirogyra species for the bioadsorption of Cu$^{+2}$ ions from aqueous solutions. FT-IR and SEM analyses were performed to characterize the phosphorylated and raw algae. The SEM analysis indicated that the phosphorus content increases by about 5 times. The isotherm equilibrium data indicated that phosphorylation enhances the removal of Cu$^{+2}$ from water by about 20%. The experimental isotherms fit well to Langmuir models with $R^{2}$ values close to 0.99. Adsorption kinetic study was conducted to investigate the effect of initial Cu$^{+2}$ concentrations, pH, …
Synthesis And In Vitro Anticancer Evaluation Of 1,4-Phenylene-Bis-Pyrimidine-2-Amine Derivatives, Meli̇ha Burcu Gürdere, Erdoğan Kamo, Ayşe Şahi̇n Yağlioğlu, Yakup Budak, Mustafa Ceylan
Synthesis And In Vitro Anticancer Evaluation Of 1,4-Phenylene-Bis-Pyrimidine-2-Amine Derivatives, Meli̇ha Burcu Gürdere, Erdoğan Kamo, Ayşe Şahi̇n Yağlioğlu, Yakup Budak, Mustafa Ceylan
Turkish Journal of Chemistry
A series of 1,4-phenylene-bis-chalcones 3a-3h were synthesized by the reaction of terephthalaldehyde with substituted arylketones in this study. The novel 1,4-phenylene-bis-pyrimidine-2-amine derivatives 5a-5h were obtained by the addition of guanidine hydrochloride to 1,4-phenylene-bis-chalcone 3a-3h in ethanolic KOH under reflux conditions. The structure of the compounds was explained by means of IR, $^{1}$H NMR, $^{13}$C NMR, and elemental analyses. The anticancer activities of 3a-3h and 5a-5h were investigated against rat brain tumor cells and human uterus carcinoma in vitro$.$ Activity tests were performed as dose-dependent assays at eight concentrations. The positive control was 5-fluorouracil (5-FU). Compounds 3c and 3d were examined …
Synthesis Of Novel Derivatives Of Chromenone Bearing An $N$-Carbamothioyl Moiety As Soybean 15-Lox Inhibitors, Robabeh Kaviani, Mina Saeedi, Mohammad Mahdavi, Hamind Nadri, Alireza Moradi, Abbas Shafiee, Tahmineh Akbarzadeh
Synthesis Of Novel Derivatives Of Chromenone Bearing An $N$-Carbamothioyl Moiety As Soybean 15-Lox Inhibitors, Robabeh Kaviani, Mina Saeedi, Mohammad Mahdavi, Hamind Nadri, Alireza Moradi, Abbas Shafiee, Tahmineh Akbarzadeh
Turkish Journal of Chemistry
Novel derivatives of chromenone bearing an $N$-carbamothioyl moiety were synthesized and evaluated for their soybean 15-LOX inhibitory activity. Synthesis of the target compounds was started from 7-hydroxy-2$H$-chromen-2-one. It was reacted with 1-fluoro-2(4)-nitrobenzene to obtain the corresponding nitrophenoxy-chromenone derivative. Reduction of the nitro group was achieved in the presence of Zn/NH$_{4}$Cl and reaction of the latter compound with in situ prepared benzoyl isothiocyanate led to the formation of the title compounds. All compounds were characterized and tested against soybean 15-LOX. Among them, 4-methyl-$N$-((4-((2-oxo-2$H$-chromen-7-yl)oxy)phenyl)carbamothioyl)benzamide (7l) showed the best activity as potent as the reference drug, quercetin.
The Structure And Cytotoxic Activity Of A New Saponin: Cephoside A From Cephalaria Elazigensis Var. Purpurea, Peyker Kayce, Nazli Boke Sarikahya, Murat Pekmez, Nazli Arda, Suheyla Kirmizigul
The Structure And Cytotoxic Activity Of A New Saponin: Cephoside A From Cephalaria Elazigensis Var. Purpurea, Peyker Kayce, Nazli Boke Sarikahya, Murat Pekmez, Nazli Arda, Suheyla Kirmizigul
Turkish Journal of Chemistry
Investigation of the aerial parts of Cephalaria elazigensis var. purpurea afforded one new oleanane-type saponin, namely cephoside A (1), and five known natural compounds (2-6). Compound 2, named anemoclemoside A, which is an unusual triterpene glycoside, was identified in the family Dipsacaceae for the first time. Chemical structures of all compounds were determined on the basis of the HRESIMS and 1D and 2D NMR data. Cephoside A (1) and anemoclemoside A (2) were assessed for their cytotoxic activities against HeLa cells, having IC$_{50}$ values of 495 and 135 $\mu $g/mL, respectively.
Fabrication Of Multilayer Graphene Oxide-Reinforced High Density Polyethylene Nanocomposites With Enhanced Thermal And Mechanical Properties Via Thermokinetic Mixing, Burcu Saner Okan
Turkish Journal of Chemistry
High density polyethylene (HDPE) was compounded with thermally exfoliated graphene oxide (TEGO) by thermokinetic mixing in a short time. High shear rates during the compounding process provided high exfoliation and proper dispersion of graphene layers in the polymer matrix. Different TEGO/polymer ratios were used to get efficient melt mixing. Structural analysis by spectroscopic techniques confirmed the exfoliation of TEGO sheets and the coverage of their surfaces by HDPE chains. Furthermore, homogeneous dispersion of graphene sheets in the matrix led to the enhancement in the mechanical and thermal properties of HPDE-based nanocomposites. Especially stress concentration sites were significantly reduced by preventing …
A Rapid, Eco-Friendly, And Reliable Microplate Method For Determination Of Cr(Vi), Alejandro Coreño Alonso, Gustavo Cruz Jimenez, Leticia Lopez Martinez, Georgina Elena Reyna Lopez, Francisco Javier Acevedo Aguilar
A Rapid, Eco-Friendly, And Reliable Microplate Method For Determination Of Cr(Vi), Alejandro Coreño Alonso, Gustavo Cruz Jimenez, Leticia Lopez Martinez, Georgina Elena Reyna Lopez, Francisco Javier Acevedo Aguilar
Turkish Journal of Chemistry
In the present work, the reaction of Cr(VI) with 1,5-diphenylcarbazide in microplates (enzyme-linked immunosorbent assay microtiter plate) and a subsequent determination in a plate reader at 540 nm were performed. The final volume utilized for each determination was 200 $\mu $L, and the cost and waste were reduced for hexavalent chromium [Cr(VI)] quantification. The use of microplates allowed for the analysis of a large number of samples, reducing analysis time. No statistically significant differences were observed between the results obtained in the analysis of Cr(VI) in real samples by the conventional procedure and by the proposed methodology in this work …
Singlet Oxygen Generation From Poly[4-Diacetoxyiodo]Styrene And Hydrogen Peroxide, Mustafa Çatir
Singlet Oxygen Generation From Poly[4-Diacetoxyiodo]Styrene And Hydrogen Peroxide, Mustafa Çatir
Turkish Journal of Chemistry
Treatment of hydrogen peroxide with a polymer-supported hypervalent iodine compound, poly[4-diacetoxyiodo] styrene (PDAIS), generates singlet molecular oxygen ($^{1}$O$_{2})$. Singlet oxygen generation was proved by trapping with typical organic compounds such as conjugated dienes, aromatic dienes, and electron-rich alkene. When compared to monomer analogue, the use of PDAIS in peroxidation of substrates gave slightly better yields (45%-96%). Regeneration and reuse of PDAIS showed similar activity. The mechanism underlying generation of singlet oxygen and reaction scope was examined.
The Reactions Of N$_{3}$P$_{3}$Cl$_{6}$ With Monodentate And Bidentate Ligands: The Syntheses And Structural Characterizations, In Vitro Antimicrobial Activities, And Dna Interactions Of 4-Fluorobenzyl(N/O)Spirocyclotriphosphazenes, Aytuğ Okumuş, Gamze Elmas, Zeynel Kiliç, Nagehan Ramazanoğlu, Leyla Açik, Mustafa Türk, Gülçi̇n Akca
The Reactions Of N$_{3}$P$_{3}$Cl$_{6}$ With Monodentate And Bidentate Ligands: The Syntheses And Structural Characterizations, In Vitro Antimicrobial Activities, And Dna Interactions Of 4-Fluorobenzyl(N/O)Spirocyclotriphosphazenes, Aytuğ Okumuş, Gamze Elmas, Zeynel Kiliç, Nagehan Ramazanoğlu, Leyla Açik, Mustafa Türk, Gülçi̇n Akca
Turkish Journal of Chemistry
The Cl replacement reactions of 4-fluorobenzyl(N/O)spirocyclotriphosphazene (2) with excess monoamines led to the formation of 4-fluorobenzylspiro(N/O)tetraaminocyclotriphosphazenes (2a-2d). The partly substituted \textbf{dispiro 3b and dispiro 3c and fully substituted trispirocyclotriphosphazenes (trans 4a, cis 4c, 4d, and 4e) were obtained, respectively, from the reactions of 2 with one equimolar and two equimolar amounts of diamines, aminoalcohol, and diols. Although efforts were made for the separation of the cis/trans and optical isomers of the dispiro phosphazenes, only one set of diastereomers (RR/RS or SS/SR) of dispiro 3b and dispiro 3c was isolated, respectively. The $^{31}$P NMR spectral data of the other dispiro phosphazenes …