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Articles 811 - 840 of 1402
Full-Text Articles in Physical Sciences and Mathematics
Gene Set Based Ensemble Methods For Cancer Classification, William Evans Duncan
Gene Set Based Ensemble Methods For Cancer Classification, William Evans Duncan
LSU Doctoral Dissertations
Diagnosis of cancer very often depends on conclusions drawn after both clinical and microscopic examinations of tissues to study the manifestation of the disease in order to place tumors in known categories. One factor which determines the categorization of cancer is the tissue from which the tumor originates. Information gathered from clinical exams may be partial or not completely predictive of a specific category of cancer. Further complicating the problem of categorizing various tumors is that the histological classification of the cancer tissue and description of its course of development may be atypical. Gene expression data gleaned from micro-array analysis …
Challenges And Rewards Of Single Crystal Flux Growth: Physical Properties Of Structurally Related Ln-Ru-Al Intermetallics, Gregory Morrison
Challenges And Rewards Of Single Crystal Flux Growth: Physical Properties Of Structurally Related Ln-Ru-Al Intermetallics, Gregory Morrison
LSU Doctoral Dissertations
The availability of single crystals is vital for understanding the intrinsic properties of crystalline materials. The flux growth method is a versatile technique which may be used to grow single crystals. However, their synthesis can often be challenging, especially when a competing phase is very robust. Herein, we study the growth competition between structurally related compounds in the Ln-Ru-Al phase space. We demonstrate the benefits of single crystals and suggest methods to grow competing phases. CeRu2Al10 has garnered interest due to its higher ordering temperate than expected from de Gennes scaling and its metal-to-insulator transition at the same temperature. Here, …
Refining The Characterization Of Projective Graphs, Perry K. Iverson
Refining The Characterization Of Projective Graphs, Perry K. Iverson
LSU Doctoral Dissertations
Archdeacon showed that the class of graphs embeddable in the projective plane is characterized by a set of 35 excluded minors. Robertson, Seymour and Thomas in an unpublished result found the excluded minors for the class of k-connected graphs embeddable on the projective plane for k = 1,2,3. We give a short proof of that result and then determine the excluded minors for the class of internally 4-connected projective graphs. Hall showed that a 3-connected graph diff_x000B_erent from K5 is planar if and only if it has K3,3 as a minor. We provide two analogous results for projective graphs. For …
Skein Theory And Topological Quantum Field Theory, Xuanting Cai
Skein Theory And Topological Quantum Field Theory, Xuanting Cai
LSU Doctoral Dissertations
Skein modules arise naturally when mathematicians try to generalize the Jones polynomial of knots. In the first part of this work, we study properties of skein modules. The Temperley-Lieb algebra and some of its generalizations are skein modules. We construct a bases for these skein modules. With this basis, we are able to compute some gram determinants of bilinear forms on these skein modules. Also we use this basis to prove that the Mahler measures of colored Jones polynomial of a sequence of knots converges to the Mahler measure of some two variable polynomial. The topological quantum field theory constructed …
Analysis Of Protein Aggregates And Synthetic Nanoparticles Using Capillary Electrophoresis With Light Scattering And Fluorescence Detection, Suresh Chandra Regmi
Analysis Of Protein Aggregates And Synthetic Nanoparticles Using Capillary Electrophoresis With Light Scattering And Fluorescence Detection, Suresh Chandra Regmi
LSU Doctoral Dissertations
The goal of the research presented in this dissertation is to develop capillary electrophoresis (CE) based analysis techniques for the characterization of individual particles including amyloid beta (Aâ) peptide aggregates and to apply these methods to study the aggregation of Aâ peptides. Protein self-assembly into ordered aggregates is a common and important process in normal biological function, but this process is also involved in several diseases. Amyloid beta peptide aggregation is linked to Alzheimer’s disease. Thioflavin T (ThT) has been used as a fluorescent probe for the detection of Aâ aggregation. Based on previous observations of false positive fluorescent signals …
Crystal Growth And An Investigation Of Structural Stability: Synthesis, Structure, And Physical Properties Of Yb(Mn,M)Xal12-X (M = Fe, Ru; X < 2.5) And Lnmnxga3 (Ln = Ho-Tm; X < 0.15), Bradford Wesley Fulfer
Crystal Growth And An Investigation Of Structural Stability: Synthesis, Structure, And Physical Properties Of Yb(Mn,M)Xal12-X (M = Fe, Ru; X < 2.5) And Lnmnxga3 (Ln = Ho-Tm; X < 0.15), Bradford Wesley Fulfer
LSU Doctoral Dissertations
The contents of this dissertation describe the crystal growth, crystal structures, and physical properties of ternary intermetallic aluminides and gallides. These compounds are grown in an effort to determine how controlling reaction ratios using the flux growth method can impact chemical structure and physical properties. Three specific examples are given where slight changes in reaction ratios leads to crystalline products that adopt various structure types. LnMn2+xAl10-x (Ln = Gd, Yb) crystals adopt the CaCr2Al10 and ThMn12 structure types. We compare LnMn2+xAl10-x compounds adopting the CaCr2Al10 and ThMn12 structure types, and outline synthesis methods to obtain each polymorph. Magnetic susceptibility measurements …
Single-Crystal Metal Oxides And Supported Metal Nanoclusters As Model Catalyst Sytems, Matthew C. Patterson
Single-Crystal Metal Oxides And Supported Metal Nanoclusters As Model Catalyst Sytems, Matthew C. Patterson
LSU Doctoral Dissertations
We have investigated the morphology and electronic structure of two basic classes of systems: metal oxide surfaces that catalyze the formation of environmentally persistent free radicals (EPFRs) from aromatic precursors, and Au and Cu nanoparticles that may be suitable catalysts for the catalytic oxidation of CO or hydrogenation of CO2. First, we examine the adsorption behavior of phenol on rutile TiO2(110) and ultrathin films of alumina prepared on a NiAl(110) substrate. Electron paramagnetic resonance studies show that exposure of both γ-alumina and titania powder to phenol at 250°C results in the formation of persistent phenoxyl radicals. EELS studies of phenol …
Oligohaline Wetland Response And Recovery Following Storm-Driven Saltwater Intrusion In Coastal Louisiana, Whitney Marie Kiehn
Oligohaline Wetland Response And Recovery Following Storm-Driven Saltwater Intrusion In Coastal Louisiana, Whitney Marie Kiehn
LSU Doctoral Dissertations
Coastal ecosystems occupy an interface between land and ocean, making them vulnerable to a variety of natural and anthropogenic disturbances. Large, episodic disturbances (mega-disturbances) cause immediate and long-lasting changes to coastal wetland plant communities and soils by changing the environmental conditions in which they exist. Here I examined the impacts of storm-induced saltwater intrusion and post-intrusion conditions on the structure and growth of an oligohaline wetland plant community, and on wetland soil biogeochemistry and conditions during and after saltwater intrusion. In the greenhouse, a six-week saltwater intrusion reduced canopy cover and species richness. Once intrusion stress was alleviated, plant community …
Design, Synthesis, And Characterization Of Porphyrin Derivatives For Biological Applications, Raja Gabadage Waruna Eranga Jinadasa
Design, Synthesis, And Characterization Of Porphyrin Derivatives For Biological Applications, Raja Gabadage Waruna Eranga Jinadasa
LSU Doctoral Dissertations
Chapter 1 of this Dissertation presents a brief introduction to the basic properties of porphyrins and their derivatives (hydroporphyrins), their abundance and functions in the nature, and their applications in photodynamic therapy. Chapter 2 reports the synthesis, characterization, conformational analysis and cellular studies of novel mono conjugated regioisomers of chlorin e6 derivatives that are promising photosensitizers for photodynamic therapy. All three regioisomers were synthesized from pheophytin a, which was extracted from the alga Spirulina pacifica. In vitro investigations using human carcinoma HEp2 cells show that the 152-lysyl regioisomers accumulate the most within cells, and the most phototoxic …
A Study Of The Temporal And Spatial Distribution Of Ichthyoplankton And Post-Larval Penaeids Recruiting Into A Louisiana Tidal Pass, Matthew John Kupchik
A Study Of The Temporal And Spatial Distribution Of Ichthyoplankton And Post-Larval Penaeids Recruiting Into A Louisiana Tidal Pass, Matthew John Kupchik
LSU Doctoral Dissertations
This dissertation attempts to better understand astronomical, meteorological, and oceanographic forcing of offshore-spawned, estuarine-dependent species from continental shelf to estuarine waters through tidal passes. The vertical distribution of zoo-/ichthyoplankton within the inner continental shelf from the Louisiana Offshore Oil Platform monitoring project (1978-1995) provided an important offshore end member for the estuarine recruitment study, and is potentially useful in predicting vulnerabilities to past and future oil spills. The role that atmospheric cold front passages may have on densities and movement of zoo-/ichthyoplankton recruiting through the Bayou Tartellan tidal pass, Louisiana, were analyzed using a Generalized Additive Model. The pre-frontal phase, …
Earth Occultation Imaging Of The Low Energy Gamma-Ray Sky With The Fermi/Gamma-Ray Burst Monitor, James Craig Rodi
Earth Occultation Imaging Of The Low Energy Gamma-Ray Sky With The Fermi/Gamma-Ray Burst Monitor, James Craig Rodi
LSU Doctoral Dissertations
The hard X-ray/soft gamma-ray sky is highly variable as source intensities can vary on timescales from fractions of a second to years. The type of sources emitting at these energies often include compact objects such as white dwarfs, neutron stars, and black holes interacting with the surrounding environment, which enables the study of the properties and characteristics of these exotic objects. Because the interactions with the environment is often through accretion, most of the emission is in X-rays and gamma-rays Frank et al. 1992 making this energy range critical to understanding the relevant physical processes and mechanisms. Hard X-ray/soft gamma-ray …
Synthesis Of The Western Hemisphere Of Theonellamide C, Saroj Yadav
Synthesis Of The Western Hemisphere Of Theonellamide C, Saroj Yadav
LSU Doctoral Dissertations
Theonellamides A-F were isolated from Theonella swinhoei by Fusetani and co-workers. Despite considerable synthetic effort to produce theonellamide F by the Shioiri group in the early 1990’s, the total synthesis of a theonellamide has yet to be reported. We report herein our efforts toward some of the required amino acid residues and construction of the western ring of theonellamide C. We describe the synthesis of an uncoded amino acid, (2S,4R)-ɣ-hydroxy-α-amino adipic acid (Ahad), a building block for theonellamide C. We initially investigated the Corey-Lygo method for the catalytic asymmetric generation of the Cα stereocenter. Unfortunately, the alkylation of glycine benzophenone …
Synthesis, Characterization And Biological Studies Of Carboranyl-Porphyrin Bioconjugates For Treatment Of Brain Tumors, Naga Venkata Satya Dinesh Kumar Bhupathiraju
Synthesis, Characterization And Biological Studies Of Carboranyl-Porphyrin Bioconjugates For Treatment Of Brain Tumors, Naga Venkata Satya Dinesh Kumar Bhupathiraju
LSU Doctoral Dissertations
Chapter 1 gives a brief introduction to brain tumors, approaches to deliver drug across the blood brain barrier (BBB), boron neutron capture therapy (BNCT) for brain tumors, application of carboranyl derivatives in attempt to treat brain tumors using BNCT. Chapter 2 involves synthesis, characterization and toxicity studies (In vitro and In vivo) of high boron containing pegylated cobaltabisdicarbollide porphyrin for treatment of brain tumors using BNCT. To improve the selectivity towards brain tumors we attempted conjugate several peptides to this non-toxic pegylated cobaltabiscabollide porphyrin. In vivo studies were conducted in collaboration with Dr. David G. Baker at LSU veterinary Medicine. …
Contractional Tectonics : The Himalayan Orogen And Perdido Fold-Thrust Belt, Dian He
Contractional Tectonics : The Himalayan Orogen And Perdido Fold-Thrust Belt, Dian He
LSU Doctoral Dissertations
This dissertation focuses on the kinematic evolution of two major categories of contractional tectonics: collisional orogenic belts and toe structures of passive margins, which are characterized by fold-thrust belts that are hundreds of kilometer-scale and tens of kilometer-scale, respectively. The Himalayan orogen is an excellent example of collisional orogenic belts along convergent plate boundaries. It is commonly structurally defined as three stacked units separated by two fault systems: the Main Central thrust (MCT) and South Tibet detachment (STD). The development and emplacement of the middle unit, the Himalayan crystalline core, has long been debated within the extrusion framework, a process …
Ionic Materials For Applications In Sensing And Optoelectronics, Sergio L. De Rooy
Ionic Materials For Applications In Sensing And Optoelectronics, Sergio L. De Rooy
LSU Doctoral Dissertations
Organic salts consist of bulky anions and/or cations whose properties can be tailored for specific purposes. Ionic liquids (ILs) are (semi)organic salts with melting points below 100 ºC. They typically exhibit neglible vapor pressures, high thermal stability, wide liquidus range, and tunable solubility. Moreover specific functions can be built into their respective ions. The first part of the dissertation involves discussions of chiral ionic liquids with additional protic, magnetic, and magneto-luminescent properties, respectively. In addition to their enantioselective sensing capabilities, the ILs may find use in chiral separations and catalysis. The second part of the dissertation involves discussions of fluorescent …
Challenges In The Discovery And Characterization Of Magnetic Intermetallics, William A. Phelan
Challenges In The Discovery And Characterization Of Magnetic Intermetallics, William A. Phelan
LSU Doctoral Dissertations
The crystal growth and characterization of four families of compounds, LnFeSb3 (Ln = Pr, Nd, Sm, Gd, and Tb) and CeCo(Sb, Sn)3, Ln2Fe4Sb5 (Ln = La – Nd and Sm), LnCu2(Al,Si)5 (Ln = La and Ce), and Ln(Cu,Al,Ga)13 (Ln = La – Pr and Eu), are presented in this dissertation. Special emphasis is placed on describing their structure-magnetic properties correlations. Discoveries and studies of these systems were motivated by their structurally related predecessors, which are comprised of complex structural subunits and exhibit unusual physical properties. The magnetic behaviors exhibited by a selection of these intermetallics include the large magnetoresistances and …
Infrared Laser Ablation For Biological Mass Spectrometry, Fan Huang
Infrared Laser Ablation For Biological Mass Spectrometry, Fan Huang
LSU Doctoral Dissertations
Instrument and technique development and modeling of ionization methods using infrared (IR) laser desorption and ablation for mass spectrometry (MS) analysis of chemical and biochemical samples are described. Infrared lasers are highly efficient at sample removal and post-ablation ionization of materials removed by IR laser can be used to improve ionization efficiency. Fundamental studies of the physical processes in laser ablation mass spectrometry can help elucidate the mechanism. In this research, an infrared/ultraviolet two-laser matrix-assisted laser desorption ionization (MALDI) MS was developed for analysis of biomolecules. An infrared laser was used to ablate a mixture of analyte and matrix, and …
Investigation Of Electroosmotic Flow Dynamics And Reproducibility In Capillary Electrophoresis, Funda Kizilkaya
Investigation Of Electroosmotic Flow Dynamics And Reproducibility In Capillary Electrophoresis, Funda Kizilkaya
LSU Doctoral Dissertations
The goal of this dissertation is to investigate electroosmotic flow (EOF) and electric field dynamics during capillary electrophoresis (CE) experiments using methods based on periodic photobleaching of fluorophores added to the separation buffer at nanomolar concentrations. The methods provide time resolved EOF and local electric field information during an experiment, which can be applied to fundamental studies to provide better understanding of CE techniques. The potential of the EOF monitoring method to improve CE migration reproducibility was investigated in Chapter 2. The EOF monitoring method and four other methods from the literature were applied to the same electrophoretic separations, and …
Red Swamp Crayfish Procambarus Clarkii In The Atchafalaya River Basin: Biotic And Abiotic Effects On Population Dynamics And Physiological Biomarkers Of Hypoxic Stress, Christopher Paul Bonvillain
Red Swamp Crayfish Procambarus Clarkii In The Atchafalaya River Basin: Biotic And Abiotic Effects On Population Dynamics And Physiological Biomarkers Of Hypoxic Stress, Christopher Paul Bonvillain
LSU Doctoral Dissertations
Crayfish harvested from the Atchafalaya River Basin (ARB) represent the majority of Louisiana wild crayfish landings. However, excluding water level influences, it is difficult to elucidate inter-annual harvest differences and intra-annual population variability among habitats. This research investigated ecological influences on population characteristics of red swamp crayfish Procambarus clarkii in the southeastern ARB as well as physiological biomarkers of hypoxic stress in P. clarkii. Biotic and abiotic effects on P. clarkii populations were examined throughout the 2008 and 2009 commercial crayfish seasons. P. clarkii catch per unit effort (CPUE) at sampling locations increased nearly 600% between sample years despite similar …
Synthesis, Cellular Studies, And Computational Analysis Of Porphyrin And Bodipy Conjugates With Affinity For Epidermal Growth Factor Receptor, Alecia Michelle Mccall
Synthesis, Cellular Studies, And Computational Analysis Of Porphyrin And Bodipy Conjugates With Affinity For Epidermal Growth Factor Receptor, Alecia Michelle Mccall
LSU Doctoral Dissertations
Chapter 1 is a description of the basic fundamental concepts of porphyrins and BODIPYs, (including synthetic methodologies), a general mechanism of the processes of EGFR, and computational concepts that are elaborated upon in future chapters. Chapter 2 is a discussion solely on the porphyrins that were synthesized to be used as fluorophores for EGFR-targeted conjugates, both peptidic and non-peptidic. The porphyrins were primarily synthesized via the Lindsey method as well as by O-alkylation of tetrahydroxy porphyrins. Synthesis of PEG linkages are discussed as well through three methodologies. Chapter 3 is a presentation of the synthesis, characterization, cellular studies, and computational …
Modeling The Spatial And Temporal Dynamics Of Coastal Marsh Birds, Bradley A. Pickens
Modeling The Spatial And Temporal Dynamics Of Coastal Marsh Birds, Bradley A. Pickens
LSU Doctoral Dissertations
Wetland birds are likely to be influenced by habitat at multiple spatial scales, yet few studies have investigated bird responses at both broad and fine scales. Northern Gulf Coast marshes are dynamic ecosystems, and they provide an ideal place to examine habitat across spatial and temporal scales. My research focused on the secretive marsh bird guild (i.e. bitterns, rails, gallinules, grebes) with an emphasis on the king rail (Rallus elegans), a species of high conservation concern. My objectives were to investigate the wetland bird-environment relationship across scales, and to model annual changes in bird distribution. Study sites were in the …
On The Witt Groups Of Schemes, Jeremy Allen Jacobson
On The Witt Groups Of Schemes, Jeremy Allen Jacobson
LSU Doctoral Dissertations
We consider two questions about the Witt groups of schemes: the first is the question of finite generation of the shifted Witt groups of a smooth variety over a finite field; the second is the Gersten conjecture. Regarding the first, we prove that the shifted Witt groups of curves and surfaces are finite, and that finite generation of the motivic cohomology groups with mod 2 coefficients implies finite generation of the Witt groups. Regarding the second, we prove the Gersten conjecture for the Witt groups in the case of a local ring that is essentially smooth over a discrete valuation …
Resonance And Double Negative Behavior In Metamaterials, Yue Chen
Resonance And Double Negative Behavior In Metamaterials, Yue Chen
LSU Doctoral Dissertations
In this work, a generic class of metamaterials is introduced and is shown to exhibit frequency dependent double negative effective properties. We develop a rigorous method for calculating the frequency intervals where either double negative or double positive effective properties appear and show how these intervals imply the existence of propagating Bloch waves inside sub-wavelength structures. The branches of the dispersion relation associated with Bloch modes are shown to be explicitly determined by the Dirichlet spectrum of the high dielectric phase and the generalized electrostatic spectra of the complement. For numerical purposes, we consider a metamaterial constructed from a sub-wavelength …
Linking Nitrogen Biogeochemistry To Different Stages Of Wetland Soil Development In The Mississippi River Delta, Louisiana, Kelly Marie Henry
Linking Nitrogen Biogeochemistry To Different Stages Of Wetland Soil Development In The Mississippi River Delta, Louisiana, Kelly Marie Henry
LSU Doctoral Dissertations
Extensive wetland loss and nutrient-enhanced eutrophication occur across the Mississippi River delta and include newly emergent landscapes, in the early stages of ecological succession, and older landscape formations, with fully developed ecological communities. Here I tested how the anthropogenic effects of a climate-induced vegetation shift, an oil spill, and nitrate-enrichment regulate the principal environmental factors controlling nutrient biogeochemistry in wetland soils at different stages of development throughout the Mississippi River delta. In the older, transgressing Barataria basin, there was no clear effect of the climate-induced species shift from Spartina alterniflora Loisel to Avicennia germinans L. on soil nutrient chemistry. Observed …
A Numerical Investigation Of Apéry-Like Recursions And Related Picard-Fuchs Equations, Maiia J. Bakhova
A Numerical Investigation Of Apéry-Like Recursions And Related Picard-Fuchs Equations, Maiia J. Bakhova
LSU Doctoral Dissertations
In this work we investigate a generalization of a recursion which was used by Apery in his proof of irrationality of the zeta function values at 2 and 3. It is a continuation of the work of Zagier , who considered generalization of the first equation and numerically investigated it. The study is made for two generalizations of the second equation, one used the mirror symmetry idea from the theory of Calabi-Yau varieties and another worked with recursion. There were discovered connections between them.
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
LSU Doctoral Dissertations
Current clinical techniques for nucleic acid detection and analysis often involve PCR, lacking adequate specificity or sensitivity to meet the stringent requirements in certain applications. This research aims to develop an innovative molecular assay and the associated hardware to rapidly signal the presence of certain targets using reporter sequence found in their genome without requiring PCR. This assay coupled the sensitivity of single-pair fluorescence resonance energy transfer (spFRET) with the specificity of ligase detection reaction (LDR) to provide near real-time readout of target biomarkers. Heightened concerns on potential bioterrorism threats, such as rapid dissemination of pathogenic bacteria or viruses into …
Energy, Environment, And Sustainability: A Hierarchical Analysis Of South Louisiana, Matthew Korbel Moerschbaecher
Energy, Environment, And Sustainability: A Hierarchical Analysis Of South Louisiana, Matthew Korbel Moerschbaecher
LSU Doctoral Dissertations
This dissertation details research into the sustainability of industrial, human, and natural systems in south Louisiana. Chapter 1 is a general introduction. Chapter 2 calculates the energy return on financial investment (EROFI) of oil and gas production in the ultra-deepwater Gulf of Mexico (GoM) in 2009 and the Macondo Prospect (Mississippi Canyon Block 252). I calculated a preliminary Energy Return on Investment (EROI) using a range of energy intensity ratios. The EROFI for ultra-deepwater oil and gas at the wellhead was roughly 0.85 gallons, per dollar. These estimates of EROI for 2009 ultra-deepwater oil and natural gas at the wellhead …
The Head And Tail Conjecture For Alternating Knots, Cody Armond
The Head And Tail Conjecture For Alternating Knots, Cody Armond
LSU Doctoral Dissertations
The colored Jones polynomial is an invariant of knots and links, which produces a sequence of Laurent polynomials. In this work, we study new power series link invariants, derived from the colored Jones polynomial, called its head and tail. We begin with a brief survey of knot theory and the colored Jones polynomial in particular. In Chapter 3, we use skein theory to prove that for adequate links, the n-th leading coefficient of the N-th colored Jones polynomial stabilizes when viewed as a sequence in N. This property allows us to define the head and tail for adequate links. In …
High-Throughput Sperm Cryopreservation Of Aquatic Species, E Hu
High-Throughput Sperm Cryopreservation Of Aquatic Species, E Hu
LSU Doctoral Dissertations
The goal of this dissertation was to integrate multiple disciplines for application of high-throughput sperm cryopreservation to aquatic species. The blue catfish Ictalurus furcatus was selected for research due to its role in production of hybrid catfish with eggs from channel catfish Ictalurus punctatus. A high-throughput cryopreservation pathway was developed by systematically evaluating each process factor and using automated processing systems. Large quantities of cryopreserved sperm produced from this protocol were evaluated in commercial-scale hatcheries in cooperation with aquaculture producers. To develop production for commercial requirements, quality characteristics of materials and products were identified and recorded during processing and analyzed …
Conformance Testing Of Peer-To-Peer Systems Using Message Traffic Analysis, John Wesley Burris
Conformance Testing Of Peer-To-Peer Systems Using Message Traffic Analysis, John Wesley Burris
LSU Doctoral Dissertations
Peer-to-Peer architectures are used by a large number of distributed systems; however, the challenges such as maintaining a reliable and stable peer-to-peer network can make such networks undesirable for distributed systems. Peer-to-peer architectures are designed to be executed on systems with diverse hardware configurations, distant geographic locations, and varied, unpredictable Internet connectivity that make the software testing process difficult. This research defines a method for conformance testing peer-to-peer content distribution systems called “Method for Conformance Testing by Analyzing Message Activity” (MCTAMA). MCTAMA uses a common representation for describing the behavior of nodes during both design and deployment. ATAMA generates, evaluates …