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University of Louisville

2013

Articles 1 - 20 of 20

Full-Text Articles in Physical Sciences and Mathematics

Re-Storing The Earth: A Phenomenological Study Of Living Sustainably, Jessica B. Buckley Dec 2013

Re-Storing The Earth: A Phenomenological Study Of Living Sustainably, Jessica B. Buckley

Faculty Scholarship

Living sustainably evokes ideas of lived, bodily engagement with and perception of the earth. Yet, modern ways of thinking and speaking have slowly alienated the earth from consciousness. Using phenomenological methods, the author examines the experience of living sustainably, exploring her own background and the idea of restoring the earth to consciousness, before examining the lives of two students dedicated to living sustainably. Components of upholding the earth, in-volving humanity, perceiving differences in studying and embodying sustainability, and engaging in choices fill the experience of living sustainably.

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Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1, Morgan E. Roberts, Jacquelyn P. Crail, Megan M. Laffoon, William G. Fernandez, Michael A. Menze, Mary E. Konkle Dec 2013

Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1, Morgan E. Roberts, Jacquelyn P. Crail, Megan M. Laffoon, William G. Fernandez, Michael A. Menze, Mary E. Konkle

Michael Menze

MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation. MitoNEET forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator. Proteomic analysis identified the specific cysteine residues that participate in the disulfide bond. This is the first report that effectively links mitoNEET to activation of the insulin regulator GDH1.

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Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1., Morgan Roberts, Jacquelyn Crail, Megan Laffoon, William Fernandez, Michael Menze, Mary Konkle Dec 2013

Identification Of Disufide Bond Formation Between Mitoneet And Glutamate Dehydrogenase 1., Morgan Roberts, Jacquelyn Crail, Megan Laffoon, William Fernandez, Michael Menze, Mary Konkle

Faculty Scholarship

MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation. MitoNEET forms a covalent complex with GDH1 through disulfide bond formation and acts as an activator. Proteomic analysis identified the specific cysteine residues that participate in the disulfide bond. This is the first report that effectively links mitoNEET to activation of the insulin regulator GDH1.

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Quantified H I Morphology – Vii. Star Formation And Tidal Influence On Local Dwarf H I Morphology., Benne W. Holwerda, N. Pirzkal, W. J. G. De Blok, S. -L. Blyth Oct 2013

Quantified H I Morphology – Vii. Star Formation And Tidal Influence On Local Dwarf H I Morphology., Benne W. Holwerda, N. Pirzkal, W. J. G. De Blok, S. -L. Blyth

Faculty Scholarship

Scale-invariant morphology parameters applied to atomic hydrogen maps (H i) of galaxies can be used to quantify the effects of tidal interaction or star formation on the interstellar matter (ISM). Here we apply these parameters, concentration, asymmetry, smoothness, Gini, M20, and the GM parameter, to two public surveys of nearby dwarf galaxies, the Very Large Array-ANGST and Local Irregulars That Trace Luminosity Extremes-The H i Nearby Galaxy Survey, to explore whether tidal interaction or the ongoing or past star formation is a dominant force shaping the H i disc of these dwarfs. Previously, H i morphological criteria were identified for …

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X-Ray Nuclear Activity In S4g Barred Galaxies : No Link Between Bar Strength And Co-Occurrent Supermassive Black Hole Fueling., Mauricio Cisternas, Dimitri A. Gadotti, Johan H. Knapen, Taehyun Kim, Simon Diaz-Garcia, Eija Laurikainen, Heikki Salo, Omaira Gonzalez-Martin, Luis C. Ho, Bruce G. Elmegreen, Dennis Zaritsky, Kartik Sheth, E. Athanassoula, Albert Bosma, Sebastien Comeron, Santiago Erroz-Ferrer, Armando Gil De Paz, Joannah L. Hinz, Benne W. Holwerda, Jarkko Laine, Sharon Meidt, Karin Menendez-Delmestre, Trisha Mizusawa, Juan Carlos Munoz-Mateos, Michael W. Regan, Mark Seibert Oct 2013

X-Ray Nuclear Activity In S4g Barred Galaxies : No Link Between Bar Strength And Co-Occurrent Supermassive Black Hole Fueling., Mauricio Cisternas, Dimitri A. Gadotti, Johan H. Knapen, Taehyun Kim, Simon Diaz-Garcia, Eija Laurikainen, Heikki Salo, Omaira Gonzalez-Martin, Luis C. Ho, Bruce G. Elmegreen, Dennis Zaritsky, Kartik Sheth, E. Athanassoula, Albert Bosma, Sebastien Comeron, Santiago Erroz-Ferrer, Armando Gil De Paz, Joannah L. Hinz, Benne W. Holwerda, Jarkko Laine, Sharon Meidt, Karin Menendez-Delmestre, Trisha Mizusawa, Juan Carlos Munoz-Mateos, Michael W. Regan, Mark Seibert

Faculty Scholarship

Stellar bars can lead to gas inflow toward the center of a galaxy and stimulate nuclear star formation. However, there is no compelling evidence on whether they also feed a central supermassive black hole: by measuring the fractions of barred active and inactive galaxies, previous studies have yielded conflicting results. In this paper, we aim to understand the lack of observational evidence for bar-driven active galactic nucleus (AGN) activity by studying a sample of 41 nearby (d < 35 Mpc) barred galaxies from the Spitzer Survey for Stellar Structure in Galaxies. We use Chandra observations to measure nuclear 2–10 keV X-ray luminosities and estimate Eddington ratios, together with Spitzer 3.6 μm imaging to quantify the strength of the stellar bar in two independent ways: (1) from its structure, as traced by its ellipticity and boxiness, and (2) from its gravitational torque Qb, taken as the maximum ratio of the tangential force to the mean background radial force. In this way, rather than discretizing the presence of both stellar bars and nuclear activity, we are able to account for the continuum of bar strengths and degrees of AGN activity. We find nuclear X-ray sources in 31 out of 41 galaxies with median X-ray luminosity and Eddington ratio of LX = 4.3×1038 erg s−1 and Lbol/LEdd = 6.9×10−6, respectively, consistent with low-luminosity AGN activity. Including upper limits for those galaxies without nuclear detections, we find no significant correlation between any of the bar strength indicators and the degree of nuclear activity, irrespective of galaxy luminosity, stellar mass, Hubble type, or bulge size. Strong bars do not favor brighter or more efficient nuclear activity, implying that at least for the low-luminosity regime, supermassive black hole fueling is not closely connected to large-scale features.

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On The Origin Of Lopsidedness In Galaxies As Determined From The Spitzer Survey Of Stellar Structure In Galaxies (S4g)., Dennis Zaritsky, Heikki Salo, Eija Laurikainen, Debra M. Elmegreen, E. Athanassoula, Albert Bosma, Sebastien Comeron, Santiago Erroz-Ferrer, Bruce G. Elmegreen, Dimitri A. Gadotti, Armando Gil De Paz, Joannah L. Hinz, Luis C. Ho, Benne W. Holwerda, Taehyun Kim, Johan H. Knapen, Jarkko Laine, Seppo Laine, Barry F. Madore, Sharon Meidt, Karin Menendez-Delmestre, Trisha Mizusawa, Juan Carlos Munoz-Mateos, Michael W. Regan, Mark Seibert, Kartik Sheth Aug 2013

On The Origin Of Lopsidedness In Galaxies As Determined From The Spitzer Survey Of Stellar Structure In Galaxies (S4g)., Dennis Zaritsky, Heikki Salo, Eija Laurikainen, Debra M. Elmegreen, E. Athanassoula, Albert Bosma, Sebastien Comeron, Santiago Erroz-Ferrer, Bruce G. Elmegreen, Dimitri A. Gadotti, Armando Gil De Paz, Joannah L. Hinz, Luis C. Ho, Benne W. Holwerda, Taehyun Kim, Johan H. Knapen, Jarkko Laine, Seppo Laine, Barry F. Madore, Sharon Meidt, Karin Menendez-Delmestre, Trisha Mizusawa, Juan Carlos Munoz-Mateos, Michael W. Regan, Mark Seibert, Kartik Sheth

Faculty Scholarship

We study the m = 1 distortions (lopsidedness) in the stellar components of 167 nearby galaxies that span a wide range of morphologies and luminosities. We confirm the previous findings of (1) a high incidence of lopsidedness in the stellar distributions, (2) increasing lopsidedness as a function of radius out to at least 3.5 exponential scale lengths, and (3) greater lopsidedness, over these radii, for galaxies of later type and lower surface brightness. Additionally, the magnitude of the lopsidedness (1) correlates with the character of the spiral arms (stronger arm patterns occur in galaxies with less lopsidedness), (2) is not …

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Herschel Observations Of Edge-On Spirals (Heroes) I. Far-Infrared Morphology And Dust Mass Determination., J. Verstappen, J. Fritz, M. Baes, M. W. L. Smith, F. Allaert, S. Bianchi, J. A. D. L. Blommaert, G. De Geyter, I. De Looze, G. Gentile, K. D. Gordon, Benne W. Holwerda, S. Viaene, E. M. Xilouris Aug 2013

Herschel Observations Of Edge-On Spirals (Heroes) I. Far-Infrared Morphology And Dust Mass Determination., J. Verstappen, J. Fritz, M. Baes, M. W. L. Smith, F. Allaert, S. Bianchi, J. A. D. L. Blommaert, G. De Geyter, I. De Looze, G. Gentile, K. D. Gordon, Benne W. Holwerda, S. Viaene, E. M. Xilouris

Faculty Scholarship

Context. Edge-on spiral galaxies with prominent dust lanes provide us with an excellent opportunity to study the distribution and properties of the dust within them. The HEROES project was set up to observe a sample of seven large edge-on galaxies across various wavelengths for this investigation. Aims. Within this first paper, we present the Herschel observations and perform a qualitative and quantitative analysis on them, and we derive some global properties of the far infrared and submillimetre emission. Methods. We determine horizontal and vertical profiles from the Herschel observations of the galaxies in the sample and describe the morphology. Modified …

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The Occulting Galaxy Pair Ugc 3995 : Dust Properties From Hst And Califa Data., Benne W. Holwerda, W. C. Keel Aug 2013

The Occulting Galaxy Pair Ugc 3995 : Dust Properties From Hst And Califa Data., Benne W. Holwerda, W. C. Keel

Faculty Scholarship

UGC 3995 is an interacting and occulting galaxy pair. UGC 3995B is a foreground face-on spiral and UGC 3995A a bright background spiral with an AGN. We present analysis of the dust in the disc of UGC 3995B based on archival Hubble Space Telescope (HST) WFPC2 and PPAK IFU data from the CALIFA survey’s first data release. From the HST F606W image, we construct an extinction map by modeling the isophotes of the background galaxy UGC 3995A and the resulting transmission through UGC 3995B. This extinction map of UGC 3995B shows several distinct spiral extinction features. The radial distribution of …

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Mixture Of Poisson Distributions To Model Discrete Stock Price Changes., Rasitha Rangani Jayasekare Kodippuli Thanthillage Dona Aug 2013

Mixture Of Poisson Distributions To Model Discrete Stock Price Changes., Rasitha Rangani Jayasekare Kodippuli Thanthillage Dona

Electronic Theses and Dissertations

An application of a mixture of Poisson distributions is proposed to model the discrete changes in stock price based on the minimum price movement known as `tick-size'. The parameters are estimated using the Expectation-Maximization (EM) algorithm with a constant mixing probability as well as mixing probabilities which depend on order size. The model is evaluated using simulations and real data. Both the simulated and real data show reasonable estimates. Several adjustments are made to the model implementation to improve the efficiency with user written codes for the Newton Raphson algorithm and also implementing one of the most recent versions of …

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The Impact Of Bars On Disk Breaks As Probed By S4g Imaging., Juan Carlos Munoz-Mateos, Kartik Sheth, Armando Gil De Paz, Sharon Meidt, E. Athanassoula, Albert Bosma, Sebastien Comeron, Debra M. Elmegreen, Bruce G. Elmegreen, Santiago Erroz-Ferrer, Dimitri A. Gadotti, Joannah L. Hinz, Luis C. Ho, Benne W. Holwerda, Thomas H. Jarrett, Taehyun Kim, Johan H. Knapen, Jarkko Laine, Eija Laurikainen, Barry F. Madore, Karin Menendez-Delmestre, Trisha Mizusawa, Michael Regan, Heikki Salo, Eva Schinnerer, Mark Seibert, Ramin Skibba, Dennis Zaritsky Jul 2013

The Impact Of Bars On Disk Breaks As Probed By S4g Imaging., Juan Carlos Munoz-Mateos, Kartik Sheth, Armando Gil De Paz, Sharon Meidt, E. Athanassoula, Albert Bosma, Sebastien Comeron, Debra M. Elmegreen, Bruce G. Elmegreen, Santiago Erroz-Ferrer, Dimitri A. Gadotti, Joannah L. Hinz, Luis C. Ho, Benne W. Holwerda, Thomas H. Jarrett, Taehyun Kim, Johan H. Knapen, Jarkko Laine, Eija Laurikainen, Barry F. Madore, Karin Menendez-Delmestre, Trisha Mizusawa, Michael Regan, Heikki Salo, Eva Schinnerer, Mark Seibert, Ramin Skibba, Dennis Zaritsky

Faculty Scholarship

We have analyzed the radial distribution of old stars in a sample of 218 nearby face-on disks, using deep 3.6μm images from the Spitzer Survey of Stellar Structure in Galaxies. In particular, we have studied the structural properties of those disks with a broken or down-bending profile. We find that, on average, disks with a genuine single-exponential profile have a scale length and a central surface brightness which are intermediate to those of the inner and outer components of a down-bending disk with the same total stellar mass. In the particular case of barred galaxies, the ratio between the break …

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Emission-Line Galaxies From The Hubble Space Telescope Probing Evolution And Reionization Spectroscopically (Pears) Grism Survey. Ii. The Complete Sample., N. Pirzkal, Barry Rothberg, Chun Ly, Sangeeta Malhotra, James E. Rhoads, Norman A. Grogin, Tomas Dahlen, Kai G. Noeske, Gerhardt R. Meurer, Jeremy R. Walsh, Nimish P. Hathi, Seth H. Cohen, Andrea Bellini, Benne W. Holwerda, Amber N. Straughn, Matthew Mechtley, Rogier A. Windhorst Jul 2013

Emission-Line Galaxies From The Hubble Space Telescope Probing Evolution And Reionization Spectroscopically (Pears) Grism Survey. Ii. The Complete Sample., N. Pirzkal, Barry Rothberg, Chun Ly, Sangeeta Malhotra, James E. Rhoads, Norman A. Grogin, Tomas Dahlen, Kai G. Noeske, Gerhardt R. Meurer, Jeremy R. Walsh, Nimish P. Hathi, Seth H. Cohen, Andrea Bellini, Benne W. Holwerda, Amber N. Straughn, Matthew Mechtley, Rogier A. Windhorst

Faculty Scholarship

We present a full analysis of the Probing Evolution And Reionization Spectroscopically (PEARS) slitess grism spectroscopic data obtained with the Advanced Camera for Surveys on board Hubble Space Telescope. PEARS covers fields within both the Great Observatories Origins Deep Survey (GOODS) North and South fields, making it ideal as a random survey of galaxies, as well as the availability of a wide variety of ancillary observations complemented by the spectroscopic results. Using the PEARS data, we are able to identify star-forming galaxies (SFGs) within the redshift volume 0 < z < 1.5. Star-forming regions in the PEARS survey are pinpointed independently of the host galaxy. This method allows us to detect the presence of multiple emission-line regions (ELRs) within a single galaxy. We identified a total of 1162 Hα, [O iii], and/or [O ii] emission lines in the PEARS sample of 906 galaxies to a limiting flux of ∼10−18 erg s−1 cm−2. The ELRs have also been compared to the properties of the host galaxy, including morphology, luminosity, and mass. From this analysis, we find three key results: (1) the computed line luminosities show evidence of a flattening in the luminosity function with increasing redshift; (2) the star-forming systems show evidence of complex morphologies with star formation occurring predominantly within one effective (half-light) radius. However, the morphologies show no correlation with host stellar mass. (3) Also, the number density of SFGs with M∗ 109 M decreases by an order of magnitude at z 0.5 relative to the number at 0.5 < z < 0.9, supporting the argument of galaxy downsizing.

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Vlt/Vimos Observations Of An Occulting Galaxy Pair : Redshifts And Effective Extinction Curve., Benne W. Holwerda, T. Boker, J. J. Dalcanton, W. C. Keel, R. S. De Jong Jun 2013

Vlt/Vimos Observations Of An Occulting Galaxy Pair : Redshifts And Effective Extinction Curve., Benne W. Holwerda, T. Boker, J. J. Dalcanton, W. C. Keel, R. S. De Jong

Faculty Scholarship

We present Very Large Telescope/Visible Multiobject Spectrograph Integral Field Unit observations of an occulting galaxy pair previously discovered in Hubble Space Telescope (HST) observations. The foreground galaxy is a low-inclination spiral disc, which causes clear attenuation features seen against the bright bulge and disc of the background galaxy. We find redshifts of z = 0.064 ± 0.003 and 0.065 for the foreground and background galaxy, respectively. This relatively small difference does not rule out gravitational interaction between the two galaxies. Emission line ratios point to a star-forming, not active galactic nuclei dominated foreground galaxy. We fit the Cardelli, Clayton and …

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The Investigation Of Protonation Of [Mo2(Nto)2(S2p(Oet)2)2(So)(Sbn)(O2cme)]., Adria Schwarber May 2013

The Investigation Of Protonation Of [Mo2(Nto)2(S2p(Oet)2)2(So)(Sbn)(O2cme)]., Adria Schwarber

College of Arts & Sciences Senior Honors Theses

No abstract provided.

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Improving Student Learning Of Organic Chemistry By The Use Of Case Comparisons., Divine-Favour Ekene Anene May 2013

Improving Student Learning Of Organic Chemistry By The Use Of Case Comparisons., Divine-Favour Ekene Anene

College of Arts & Sciences Senior Honors Theses

No abstract provided.

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Homological Algebra : Tor Functors, Betti Numbers, And Free Resolutions., Ian Philipp May 2013

Homological Algebra : Tor Functors, Betti Numbers, And Free Resolutions., Ian Philipp

College of Arts & Sciences Senior Honors Theses

The topic of study for this project is homological algebra, a branch of mathematics with applications to a plethora of other branches of mathematics as well as sensor networks, signal processing, uid dynamics, particle physics, etc. The amount of literature written on this topic is vast and there are numerous open problems in homological algebra, but this project has a more modest focus. First, we will explain the fundamental terminology with several examples and later we will proceed to some results concerning certain rings and ideals, and then results about modules generated by zero divisors.

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Examining The Substrate Specificity Of Factor Xiiia Towards Peptide Substrate Modelsac Fibrin Domains., Jacob Bell May 2013

Examining The Substrate Specificity Of Factor Xiiia Towards Peptide Substrate Modelsac Fibrin Domains., Jacob Bell

College of Arts & Sciences Senior Honors Theses

In the blood coagulation cascade, Factor XIII (FXIII) is a zymogen that is activated by thrombin (IIa) and Ca2+. Activated FXIII (FXIIIa) functions as a transglutaminase in the final steps of the clotting cascade by forming covalent crosslinks between fibrin monomers at reactive glutamine residues. This forms a stable clot structure, secure from proteolytic degradation. To monitor FXIIIa substrate sequence specificity, the glutamine-containing peptide models S. aureus Fnb A (100-114), α2AP(Q4P) (1-15) and K9 (1-10) were introduced to the enzyme in the presence of 15NH4Cl. Using MALDI-TOF MS and 15N HSQC NMR experiments, it was seen that α2AP(Q4P) (1-15) and …

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Compound Identification Using Penalized Linear Regression., Ruiqi Liu May 2013

Compound Identification Using Penalized Linear Regression., Ruiqi Liu

Electronic Theses and Dissertations

In this study, we propose a new method for compound identification using penalized linear regression. Compound identification is often achieved by matching the experimental mass spectra to the mass spectra stored in a reference library based on mass spectral similarity. In the context of the linear regression, the response variable is an experimental mass spectrum (i.e., query) and all the compounds in the reference library are the independent variables. However, the number of compounds in the reference library is much larger than the range of m/z values so that the data become high dimensional data with suffering from singularity. For …

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Testing Galaxy Formation Models With The Ghosts Survey : The Color Profile Of M81'S Stellar Halo., Antonela Monachesi, Eric F. Bell, David J. Radburn-Smith, Marija Vlajic, Roelof S. De Jong, Jeremy Bailin, Julianne J. Dalcanton, Benne W. Holwerda, David Streich Apr 2013

Testing Galaxy Formation Models With The Ghosts Survey : The Color Profile Of M81'S Stellar Halo., Antonela Monachesi, Eric F. Bell, David J. Radburn-Smith, Marija Vlajic, Roelof S. De Jong, Jeremy Bailin, Julianne J. Dalcanton, Benne W. Holwerda, David Streich

Faculty Scholarship

We study the properties of the stellar populations in M81’s outermost part, which hereafter we will call the stellar halo, using Hubble Space Telescope (HST) Advanced Camera for Surveys observations of 19 fields from the GHOSTS survey. The observed fields probe the stellar halo out to a projected distance of ∼50 kpc from the galactic center. Each field was observed in both F606W and F814W filters. The 50% completeness levels of the color–magnitude diagrams (CMDs) are typically at 2 mag below the tip of the red giant branch (TRGB). Fields at distances closer than 15 kpc show evidence of disk-dominated …

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The Opacity Of Spiral Galaxy Disks : Ix. Dust And Gas Surface Densities., Benne W. Holwerda, R. J. Allen, W. J. G. De Blok, A. Bouchard, R. A. Gonzalez-Lopezlira, P. C. Van Der Kruit, A. Leroy Mar 2013

The Opacity Of Spiral Galaxy Disks : Ix. Dust And Gas Surface Densities., Benne W. Holwerda, R. J. Allen, W. J. G. De Blok, A. Bouchard, R. A. Gonzalez-Lopezlira, P. C. Van Der Kruit, A. Leroy

Faculty Scholarship

Our aim is to explore the relation between gas, atomic and molecular, and dust in spiral galaxies. Gas surface densities are from atomic hydrogen and CO line emission maps. To estimate the dust content, we use the disk opacity as inferred from the number of distant galaxies identified in twelve HST/WFPC2 fields of ten nearby spiral galaxies. The observed number of distant galaxies is calibrated for source confusion and crowding with artificial galaxy counts and here we verify our results with sub-mm surface brightnesses from archival Herschel-SPIRE data. We find that the opacity of the spiral disk does not correlate …

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Galaxy Zoo : A Catalog Of Overlapping Galaxy Pairs For Dust Studies., William C. Keel, Anna M. Manning, Benne W. Holwerda, Massimo Mezzoprete, Chris J. Lintott, Kevin Schawinski, Pamela Gay, Karen L. Masters Jan 2013

Galaxy Zoo : A Catalog Of Overlapping Galaxy Pairs For Dust Studies., William C. Keel, Anna M. Manning, Benne W. Holwerda, Massimo Mezzoprete, Chris J. Lintott, Kevin Schawinski, Pamela Gay, Karen L. Masters

Faculty Scholarship

Analysis of galaxies with overlapping images offers a direct way to probe the distribution of dust extinction and its effects on the background light. We present a catalog of 1990 such galaxy pairs selected from the Sloan Digital Sky Survey (SDSS) by volunteers of the Galaxy Zoo project. We highlight subsamples which are particularly useful for retrieving such properties of the dust distribution as UV extinction, the extent perpendicular to the disk plane, and extinction in the inner parts of disks. The sample spans wide ranges of morphology and surface brightness, opening up the possibility of using this technique to …

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