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Articles 61 - 71 of 71
Full-Text Articles in Physical Sciences and Mathematics
Using Building Energy Simulation And Geospatial Modeling Techniques In Determine High Resolution Building Sector Energy Consumption Profiles, Shem C. Heiple
Using Building Energy Simulation And Geospatial Modeling Techniques In Determine High Resolution Building Sector Energy Consumption Profiles, Shem C. Heiple
Dissertations and Theses
A technique is presented for estimating hourly and seasonal energy consumption profiles in the building sector at spatial scales down to the individual taxlot or parcel. The method combines annual building energy simulations for cityspecific prototypical buildings and commonly available geospatial data in a Geographical Information System (GIS) framework. Hourly results can be extracted for any day and exported as a raster output at spatial scales as fine as an individual parcel (
Why Don’T People Use Refactoring Tools?, Andrew P. Black, Emerson Murphy-Hill
Why Don’T People Use Refactoring Tools?, Andrew P. Black, Emerson Murphy-Hill
Computer Science Faculty Publications and Presentations
Tools that perform refactoring are currently under-utilized by programmers. As more advanced refactoring tools are designed, a great chasm widens between how the tools must be used and how programmers want to use them. In this position paper, we characterize the dominant process of refactoring, demonstrate that many research tools do not support this process, and initiate a call to action for designers of future refactoring tools.
Cache Coherence Protocol Verification Using Ωmega, Ki Yung Ahn
Cache Coherence Protocol Verification Using Ωmega, Ki Yung Ahn
Computer Science Faculty Publications and Presentations
We verify some correctness properties of the DASH cache coherence protocol using Ωmega. Ωmega is a language with a rich type system featuring GADTs, type functions, and user-guided type checking rules. Cache coherence protocols have both safety properties and liveness properties. We show how to describe some of the safety properties of DASH cache coherence protocol in mega. Since liveness properties are not easily expressed by types, we investigate invariants sufficient to imply some of the liveness properties of concern, and assert those invariants as well in the type system of Ωmega. Using Ωmega, we can have both a working …
Protecting The Internet With Public Work, Ed Kaiser, Wu-Chang Feng
Protecting The Internet With Public Work, Ed Kaiser, Wu-Chang Feng
Computer Science Faculty Publications and Presentations
Distributed denial-of-service attacks represent a growing problem for networked systems. To tackle this problem, this paper explores the addition of a public work function to the service advertisement mechanisms used by such systems. When under attack, services advertise this function along with their location information and clients must attach a solution to the function with subsequent requests. The function, which can be made specific to the source of traffic, is publicly verifiable, allowing arbitrary network devices at the edges of the network to quickly verify that subsequent communication from the source will be accepted by the destination. We describe a …
Directflow: A Domain-Specific Language For Information-Flow Systems, Andrew P. Black, Chuan-Kai Lin
Directflow: A Domain-Specific Language For Information-Flow Systems, Andrew P. Black, Chuan-Kai Lin
Computer Science Faculty Publications and Presentations
Programs that process streams of information are commonly built by assembling reusable information-flow components. In some systems the components must be chosen from a pre-defined set of primitives; in others the programmer can create new custom components using a general-purpose programming language. Neither approach is ideal: restricting programmers to a set of primitive components limits the expressivity of the system, while allowing programmers to define new components in a general-purpose language makes it difficult or impossible to reason about the composite system. We advocate defining information-flow components in a domain-specific language (DSL) that enables us to infer the properties of …
Modular Polyketide Synthases And Cis Double Bond Formation: Establishment Of Activated Cis-3-Cyclohexylpropenoic Acid As The Diketide Intermediate In Phoslactomycin Biosynthesis, Mamoun M. Alhamadsheh, Nadaraj Palaniappan, Suparna Daschouduri, Kevin A. Reynolds
Modular Polyketide Synthases And Cis Double Bond Formation: Establishment Of Activated Cis-3-Cyclohexylpropenoic Acid As The Diketide Intermediate In Phoslactomycin Biosynthesis, Mamoun M. Alhamadsheh, Nadaraj Palaniappan, Suparna Daschouduri, Kevin A. Reynolds
Chemistry Faculty Publications and Presentations
The majority of modular polyketide synthase (PKS) systems which generate unsaturated products do so with trans double bonds. Phoslactomycin B (PLM B) presents a class of antitumor and antiviral natural polyketide products that have unique structural features, including a linear unsaturated backbone with one trans and three cis double bonds. There is substantial evidence that trans double bonds are established by ketoreductase-dehydratase (KR-DH) didomains within a PKS module. In cases where modules containing these didomains appear to generate product containing a cis double bond there is no experimental evidence to determine if they do so directly, or if they also …
Locally Conservative Fluxes For The Continuous Galerkin Method, Bernardo Cockburn, Jay Gopalakrishnan, Haiying Wang
Locally Conservative Fluxes For The Continuous Galerkin Method, Bernardo Cockburn, Jay Gopalakrishnan, Haiying Wang
Mathematics and Statistics Faculty Publications and Presentations
The standard continuous Galerkin (CG) finite element method for second order elliptic problems suffers from its inability to provide conservative flux approximations, a much needed quantity in many applications. We show how to overcome this shortcoming by using a two step postprocessing. The first step is the computation of a numerical flux trace defined on element inter- faces and is motivated by the structure of the numerical traces of discontinuous Galerkin methods. This computation is non-local in that it requires the solution of a symmetric positive definite system, but the system is well conditioned independently of mesh size, so it …
Stochastic Comparisons Of Parallel Systems When Component Have Proportional Hazard Rates, Subhash C. Kochar, Maochao Xu
Stochastic Comparisons Of Parallel Systems When Component Have Proportional Hazard Rates, Subhash C. Kochar, Maochao Xu
Mathematics and Statistics Faculty Publications and Presentations
Let Χ1, … Χn be independent random variables with Χᵢ having survival function Fλᵢ, i=1, … , n, and let Y₁, … , Yn be a random sample with common population survival distribution Fλ, where λ = Σᵢ=₁nλᵢl n. Let Χn:n and Yn:n denote the lifetimes of the parallel systems consisting of these components, respectively. It is shown that Xn:n is greater than Yn:n in terms of likelihood ratio order. It is also proved that the sample range Χn:n - Χ₁:n is larger than Yn n:n - Y₁:n according to reverse hazard rate ordering. These two results …
Some Recent Results On Stochastic Comparisons And Dependence Among Order Statistics In The Case Of Phr Model, Subhash C. Kochar, Maochao Xu
Some Recent Results On Stochastic Comparisons And Dependence Among Order Statistics In The Case Of Phr Model, Subhash C. Kochar, Maochao Xu
Mathematics and Statistics Faculty Publications and Presentations
This paper reviews some recent results on stochastic orders and dependence among order statistics when the observations are independent and follow the proportional hazard rates model.
The Topology Of Surface Mediatrices, James Bernhard, J. J. P. Veerman
The Topology Of Surface Mediatrices, James Bernhard, J. J. P. Veerman
Mathematics and Statistics Faculty Publications and Presentations
Given a pair of distinct points p and q in a metric space with distance d, the mediatrix is the set of points x such that d(x,p)=d(x,q). In this paper, we examine the topological structure of mediatrices in connected, compact, closed 2-manifolds whose distance function is inherited from a Riemannian metric. We determine that such mediatrices are, up to homeomorphism, finite, closed simplicial 1-complexes with an even number of incipient edges emanating from each vertex. Using this and results from [J.J.P. Veerman, J. Bernhard, Minimally separating sets, mediatrices and Brillouin spaces, Topology Appl., in press], we give the classification …
Probing Reactivity And Substrate Specificity Of Both Subunits Of The Dimeric Mycobacterium Tuberculosis Fabh Using Alkyl-Coa Disulfide Inhibitors And Acyl-Coa Substrates, Sarbjot Sachdeva, Faik Musayev, Mamoun M. Alhamadsheh, J. Neel Scarsdale, H. Tonie Wright, Kevin A. Reynolds
Probing Reactivity And Substrate Specificity Of Both Subunits Of The Dimeric Mycobacterium Tuberculosis Fabh Using Alkyl-Coa Disulfide Inhibitors And Acyl-Coa Substrates, Sarbjot Sachdeva, Faik Musayev, Mamoun M. Alhamadsheh, J. Neel Scarsdale, H. Tonie Wright, Kevin A. Reynolds
Chemistry Faculty Publications and Presentations
The dimeric Mycobacterium tuberculosis FabH (mtFabH) catalyses a Claisen-type condensation between an acyl-CoA and malonyl-acyl carrier protein (ACP) to initiate the Type II fatty acid synthase cycle. To analyze the initial covalent acylation of mtFabH with acyl-CoA, we challenged it with mixture of C6-C20 acyl-CoAs and the ESI-MS analysis showed reaction at both subunits and a strict specificity for C12 acyl CoA. Crystallographic and ESI-MS studies of mtFabH with a decyl-CoA disulfide inhibitor revealed a decyl chain bound in acyl-binding channels of both subunits through disulfide linkage to the active site cysteine. These data provide the first unequivocal evidence that …