Physical Sciences and Mathematics Commons^™

Design, Synthesis, And Kinetic Study Of The First Generation Phenyloxadiazole Compounds And The Second Generation Phenyloxadiazole Compounds And Highly Selective Hydroboration Of Alkenes, Ketones And Aldehydes Catalyzed By A Well-Defined Manganese Complex, Haisu Zeng

Dissertations, Theses, and Capstone Projects

This thesis focuses on two projects. In the first project, my goal was to discover a new variant of phenyloxadiazole compounds that could exhibit increased thiol-reactivity during bioconjugation processes. To achieve this, I synthesized several phenyloxadiazole derivatives and subjected them to NMR kinetic studies to assess their reactivity with a model thiol. Based on the results, I was able to identify a phenyloxadiazole analog that demonstrated enhanced reactivity, which included a chlorine atom located in the meta-position of the phenyl ring.

I provided a detailed description of the synthesis and characterization of the newly discovered phenyloxadiazole analog and demonstrate its …

Shedding Light On Dark Patterns: A Case Study On Digital Harms, Noreen Y. Whysel

Publications and Research

You’ve been there before. You thought you could trust someone with a secret. You thought it would be safe, but found out later that they blabbed to everyone. Or maybe they didn’t share it, but the way they used it felt manipulative. You gave more than you got and it didn’t feel fair. But now that it’s out there, do you even have control anymore?

Ok. Now imagine that person was your supermarket. Or your bank. Or your boss.

As designers of digital spaces for consumer products and services, how often do we consider the relationship we have with our …

Personas, Scenarios And Storyboards, Devorah Kletenik

Open Educational Resources

This activity guides students towards the creation of personas, scenarios and storyboards for a product/website that they are creating.

Data Mining For Design Flood Prediction, James E. Ball

International Conference on Hydroinformatics

Design flood estimation remains a problem for many professionals involved in the management of rural and urban catchments. Advice is required regarding design flood characteristics for many design problems including the design of culverts and bridges necessary for cross drainage of transport routes, the design of urban drainage systems, the design of flood mitigation levees and other flood mitigation structures, design of dam spillways, and many environmental flow problems. When a risk based approach is adopted as the design paradigm, there is a need to predict both the magnitude of the hazard and the exceedance probability of the hazard. In …

Comparison Of Various Phased Approaches For The Constrained Minimum-Cost Design Of Water Distribution Networks, Enrico Creaco, Marco Franchini, Tom Walski

International Conference on Hydroinformatics

This work is aimed at analyzing and comparing three different phased approaches for constrained minimum-cost design of water distribution networks: the single-step design with demand feedback, the multi-step design without demand feedback and the multi-step design with demand feedback. The difference between the single-step design and the multi-step design lies in the fact that whereas the former entails optimizing a single construction step at a time, i.e. the current construction phase, the latter is based on the phasing of construction and then is aimed at optimizing the current construction phase and all the subsequent phases, included inside a certain temporal …

A New Methodology For The Design Of Residential Water Distribution Networks And Its Population Range Of Application., Daniel Vallejo, Juan Guillermo Saldarriaga, Diego Alejandro Páez, Santiago Serrano

International Conference on Hydroinformatics

For the design of a Water Distribution Systems (WDS) or for Residential Water Networks (RWN) different assumptions have to be made. This implies that the design methodologies for each of the two kinds of networks differ between them and so it is important to define a population value that limits the applicability of each method. This paper will present a new methodology for the RWN’s design process as well as the calculation the population limit. For designing the RWN demands’ predictions have to be made. The new methodology uses the concept of Poisson Rectangular Pulses (PRP) for modeling the water …