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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

Bucknell University

Honors Theses

2021

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Full-Text Articles in Physical Sciences and Mathematics

Perceptually Improved Medical Image Translations Using Conditional Generative Adversarial Networks, Anurag Vaidya Jan 2021

Perceptually Improved Medical Image Translations Using Conditional Generative Adversarial Networks, Anurag Vaidya

Honors Theses

Magnetic resonance imaging (MRI) can help visualize various brain regions. Typical MRI sequences consist of T1-weighted sequence (favorable for observing large brain structures), T2-weighted sequence (useful for pathology), and T2-FLAIR scan (useful for pathology with suppression of signal from water). While these different scans provide complementary information, acquiring them leads to acquisition times of ~1 hour and an average cost of $2,600, presenting significant barriers. To reduce these costs associated with brain MRIs, we present pTransGAN, a generative adversarial network capable of translating both healthy and unhealthy T1 scans into T2 scans. We show that the addition of non-adversarial …