Physical Sciences and Mathematics Commons^™

Video Prediction With Invertible Linear Embeddings, Robert Thomas Pottorff

Theses and Dissertations

Using recently popularized invertible neural network We predict future video frames from complex dynamic scenes. Our invertible linear embedding (ILE) demonstrates successful learning, prediction and latent state inference. In contrast to other approaches, ILE does not use any explicit reconstruction loss or simplistic pixel-space assumptions. Instead, it leverages invertibility to optimize the likelihood of image sequences exactly, albeit indirectly.Experiments and comparisons against state of the art methods over synthetic and natural image sequences demonstrate the robustness of our approach, and a discussion of future work explores the opportunities our method might provide to other fields in which the accurate analysis …

Deep Synthetic Noise Generation For Rgb-D Data Augmentation, Patrick Douglas Hammond

Theses and Dissertations

Considerable effort has been devoted to finding reliable methods of correcting noisy RGB-D images captured with unreliable depth-sensing technologies. Supervised neural networks have been shown to be capable of RGB-D image correction, but require copious amounts of carefully-corrected ground-truth data to train effectively. Data collection is laborious and time-intensive, especially for large datasets, and generation of ground-truth training data tends to be subject to human error. It might be possible to train an effective method on a relatively smaller dataset using synthetically damaged depth-data as input to the network, but this requires some understanding of the latent noise distribution of …

Mechanically Scanned Interference Pattern Structured Illumination Imaging, Jarom Silver Jackson

Theses and Dissertations

A method of lensless, single pixel imaging is presented. This method, referred to as MAS-IPSII, is theoretically capable of resolutions as small as one quarter of the wavelength of the imaging light. The resolution is not limited by the aperture of any optic, making high resolutions (including subwavelength) feasible even at very large (greater than a meter) distances. Imaging requires only flat optics and a coherent source, making it a good candidate for imaging with extreme wavelengths in the UV and x-ray regimes. The method is demonstrated by the imaging of various test targets. Both real and complex imaging (i.e. …

Geological And Geochemical Controls On Non-Tuberculous Mycobacterium Transmission: Examples From Hawaii, Schuyler Thomas Robinson

Theses and Dissertations

The opportunistic environmental microbes, non-tuberculous Mycobacterium (NTM), pose an increasing risk of disease and death in both immunodeficient and immunocompetent individuals in the USA and across the world. NTM lung disease is particularly prevalent in Hawaii, although the modes of NTM acquisition and transport in Hawaii are not fully understood. This study evaluated 149 soil and 50 water samples across the Hawaiian Islands to determine geochemical factors controlling NTM. Non-metric multidimensional scaling (NMDS) and principal component analyses (PCA) of modern soils show variables such as Total Organic Carbon (TOC), pH, P, mafic silicate minerals, and Pb seem to control NTM …

Necessary And Sufficient Conditions On State Transformations That Preserve The Causal Structure Of Lti Dynamical Networks, Chi Ho Leung

Theses and Dissertations

Linear time-invariant (LTI) dynamic networks are described by their dynamical structure function, and generally, they have many possible state space realizations. This work characterizes the necessary and sufficient conditions on a state transformation that preserves the dynamical structure function, thereby generating the entire set of realizations of a given order for a specific dynamic network.

Noise Control Of Vacuum-Assisted Toilets, Michael Thomas Rose

Theses and Dissertations

Vacuum-assisted toilets make use of a large pressure difference between the ambient pressure and a vacuum tank to transport waste from the toilet bowl to the septic tank. This process requires 98% less water per flush making it an attractive product for transport vehicles such as airplanes, cruise ships, and trains. Unfortunately, the water savings come at the cost of high noise levels. This thesis investigates the acoustic characteristics of a vacuum-assisted toilet flush and several methods to reduce the radiated noise. Some methods include changing rinse parameters such as rinse pressure, rinse length, and rinse timing, adding structural damping …

Using Symmetry To Accelerate Materials Discovery, Wiley Spencer Morgan

Theses and Dissertations

Computational methods are commonly used by materials scientists to make predictions about materials. These methods can achieve in hours what would take days or weeks to accomplish in a lab. However, there are limits to what computational methods can do and how accurate the predictions are.A limiting factor for computational materials science is the size of the search space. The space of potential materials is infinite. Selecting specific systems of elements on a fixed lattice to study reduces the number of possible arrangements of atoms in the lattice to a finite number. However, this number can still be very large. …

Design And Synthesis Of Ceragenins–Cationic Steroid Antimicrobial Compounds, Structural Improvement And Synthesis Of Cyclopentenone Prostaglandins And Modification And Synthesis Of Derivatives Of Ribityllumazines: Potential Antigens For Activation Of Mait Cells, Yubo Li

Theses and Dissertations

Antimicrobial peptides (AMPs) are ubiquitous and display broad-spectrum antimicrobial activity that can control bacterial colonization of surfaces. Ceragenins are small-molecule mimics of AMPs and have several advantages over AMPs, including cost of manufacture and stability. A ceragenin, CSA-120, modified with an acrylamide group was directly incorporated into fluoropolymer coatings as a means of inhibiting bacterial biofilm formation. The ceragenin-containing coatings displayed improved performance. By conjugating a copper chelating group to the ceragenin, chelation of 64Cu by the conjugate was effective and provided a stable complex that allowed in vivo imaging. This conjugate may provide a means of identifying infection sites …

Deciphering The Transport Of Elastic Filaments By Antagonistic Motor Proteins, Stephanie Portet, Cecil Leduc, Sandrine Etienne-Manneville, J. C. Dallon

Faculty Publications

Intermediate filaments are long elastic fibres that are transported by microtubule-associated motor proteins kinesin and dynein inside the cell. How elastic filaments are efficiently transported by antagonistic motors is not well understood and difficult to measure with current experimental techniques. Adapting the tug-of-war paradigm for vesicle-like cargos, we develop a mathematical model to describe the motion of an elastic filament punctually bound to antagonistic motors. As observed in cells, up to 3 modes of transport are obtained; dynein-driven retrograde, kinesin-driven anterograde fast motions and a slow motion. Motor properties and initial conditions that depend on intracellular context, regulate the transport …

Deep Learning For Document Image Analysis, Christopher Alan Tensmeyer

Theses and Dissertations

Automatic machine understanding of documents from image inputs enables many applications in modern document workflows, digital archives of historical documents, and general machine intelligence, among others. Together, the techniques for understanding document images comprise the field of Document Image Analysis (DIA). Within DIA, the research community has identified several sub-problems, such as page segmentation and Optical Character Recognition (OCR). As the field has matured, there has been a trend of moving away from heuristic-based methods, designed for particular tasks and domains of documents, and moving towards machine learning methods that learn to solve tasks from examples of input/output pairs. Within …

Representation And Reconstruction Of Linear, Time-Invariant Networks, Nathan Scott Woodbury

Theses and Dissertations

Network reconstruction is the process of recovering a unique structured representation of some dynamic system using input-output data and some additional knowledge about the structure of the system. Many network reconstruction algorithms have been proposed in recent years, most dealing with the reconstruction of strictly proper networks (i.e., networks that require delays in all dynamics between measured variables). However, no reconstruction technique presently exists capable of recovering both the structure and dynamics of networks where links are proper (delays in dynamics are not required) and not necessarily strictly proper.The ultimate objective of this dissertation is to develop algorithms capable of …

Multi-Instrument Surface Characterization Of Display Glass, Cody Vic Cushman

Theses and Dissertations

Flat panel displays (FPDs) are microfabricated devices that are often fabricated on specialized glass substrates known as display glass. The surface chemistry of the outer few nanometers of display glass can have an important influence on FPD performance and yield. Dsiplay glass surface characterization is difficult because (i) display glass surface composition varies significantly from its bulk composition; (ii) high-surface area forms of glass, such as fibers and powders, may not have the same surface composition as melt-formed planar surfaces, and (iii) the surface composition of display glass may be altered through exposure to chemical treatments commonly used during flat …

Antibacterial And Antifungal Activity Of Ceragenins, Mimics Of Endogenous Antimicrobial Peptides, Marjan Mohammadihashemi

Theses and Dissertations

The continuous emergence of drug-resistance pathogens is a global concern. As a result, substantial effort is being expended to develop new therapeutics and mechanisms for controlling microbial growth to avoid entering a "post-antibiotic" era in which commonly used antibiotics are no longer effective in treating infections. In this work, we investigate the efficacy and application of ceragenins as non-peptide mimics of antimicrobial peptides (AMPs). First, this work examines the susceptibility of drug-resistant Gram-negative bacteria. The susceptibility of colistin-resistant clinical isolates of Klebsiella pneumoniae to ceragenins and AMPs suggests that there is little to no cross-resistance between colistin and ceragenins/AMPs. Furthermore, …

Moderating Influence As A Design Principle For Human-Swarm Interaction, C Chace Ashcraft

Theses and Dissertations

Robot swarms have recently become of interest in both industry and academia for their potential to perform various difficult or dangerous tasks efficiently. As real robot swarms become more of a possibility, many desire swarms to be controlled or directed by a human, which raises questions regarding how that should be done. Part of the challenge of human-swarm interaction is the difficulty of understanding swarm state and how to drive the swarm to produce emergent behaviors. Human input could inhibit desirable swarm behaviors if their input is poor and has sufficient influence over swarm agents, affecting its overall performance. Thus, …

The Investigation Of Nickel-Based Catalysts For The Oxidative Dehydrogenation Of Ethane, Justin Lane Park

Theses and Dissertations

The Investigation of Nickel-Based Catalysts for the Oxidative Dehydrogenation of Ethane Justin Lane ParkDepartment of Chemistry & Biochemistry, BYU Doctor of Philosophy Chemistry The advancement of creating ethylene from ethane via oxidative dehydrogenation (ODH) rather than the traditional direct dehydrogenation is right on the cusp of commercialization. The oxidative pathway provides a novel route that reduces the operating temperature of this reaction by 400-500°C. A variety of metals including Mo, V, and Ni that have redox properties suitable for the partial oxidation of small chain alkanes have been investigated. Currently, a MoVNbTe oxide is the most promising catalyst but it …

Hot Springs Inflow Controlled By The Damage Zone Of A Major Normal Fault, Steven Benjamin Godwin

Theses and Dissertations

Spring water inflow is distinct at Pah Tempe Hot Springs (also known as Dixie Hot Springs) situated within the damage zone of the Hurricane Fault in Timpoweap Canyon in Hurricane, Utah. Excising of the footwall by the Virgin River has created Timpoweap Canyon and allowed an unusual opportunity to study the spring inflow in relation to the fault damage zone. While correlation of these springs with the damage zone and visible fracture patterns on the canyon wall has been made, no subsurface faulting has been imaged to verify connection to these visible fractures and spring inflows (Nelson et al., 2009). …

Exponential Stability Of Intrinsically Stable Dynamical Networks And Switched Networks With Time-Varying Time Delays, David Patrick Reber

Theses and Dissertations

Dynamic processes on real-world networks are time-delayed due to finite processing speeds and the need to transmit data over nonzero distances. These time-delays often destabilize the network's dynamics, but are difficult to analyze because they increase the dimension of the network.We present results outlining an alternative means of analyzing these networks, by focusing analysis on the Lipschitz matrix of the relatively low-dimensional undelayed network. The key criteria, intrinsic stability, is computationally efficient to verify by use of the power method. We demonstrate applications from control theory and neural networks.

Regular Fibrations Over The Hawaiian Earring, Stewart Mason Mcginnis

Theses and Dissertations

We present a family of fibrations over the Hawaiian earring that are inverse limits of regular covering spaces over the Hawaiian earring. These fibrations satisfy unique path lifting, and as such serve as a good extension of covering space theory in the case of nonsemi-locally simply connected spaces. We give a condition for when these fibrations are path-connected.

After Https: Indicating Risk Instead Of Security, Matthew Wayne Holt

Theses and Dissertations

Browser security indicators show warnings when sites load without HTTPS, but more malicious sites are using HTTPS to appear legitimate in browsers and deceive users. We explore a new approach to browser indicators that overcomes several limitations of existing indicators. First, we develop a high-level risk assessment framework to identify risky interactions and evaluate the utility of this approach through a survey. Next, we evaluate potential designs for a new risk indicator to communicate risk rather than security. Finally, we conduct a within-subjects user study to compare the risk indicator to existing security indicators by observing participant behavior and collecting …

On The Persecution Of The Salvadoran People, Jacob Newman

Undergraduate Honors Theses

El Salvador is the focal point of an American refugee crisis. This crisis owes its origins to protracted abuse and negligence suffered by the Salvadoran people. They are confronted with violence, apathy, and corruption in their homeland and throughout the international sphere. A complex system of harms has come to a concentrated fruition in the form of governments and gangs, histories and happenstance. The purpose of this thesis is, first, to document the persecution faced by Salvadorans and, second, argue that the conditions in El Salvador put many Salvadorans in need of asylum.

Computational Regiospecific Analysis Of Brain Lipidomic Profiles, Austin Ahlstrom

Undergraduate Honors Theses

Mass spectrometry provides an extensive data set that can prove unwieldy for practical analytical purposes. Applying programming and machine learning methods to automate region analysis in DESI mass spectrometry of mouse brain tissue can help direct and refine such an otherwise unusable data set. The results carry promise of faster, more reliable analysis of this type, and yield interesting insights into molecular characteristics of regions of interest within these brain samples. These results have significant implications in continued investigation of molecular processes in the brain, along with other aspects of mass spectrometry, collective analysis of biological molecules (i.e. omics), and …

Computationally Modeling The Trophic Cascade In Yellowstone National Park, Emily Menden

Undergraduate Honors Theses

Many of the world’s ecosystems are facing species elimination (2). Whether this elimination is intentional or accidental, the consequences need to be understood in order to make better resource management decisions. Computational models can be helpful in making these management decisions. Yellowstone National Park gives ecologists a unique opportunity to study species elimination and reintroduction.

In the 1920s, wolves were extirpated from the Greater Yellowstone Area. The absence of wolves allowed the elk population to increase unbounded by a natural predator. Over the years, Yellowstone management took various measures to control the elk population. In the 1970s, the National Park …

Stochastic Modeling Reveals How Motor Protein And Filament Properties Affect Intermediate Filament Transport, J. C. Dallon, Cecil Leduc, Sandrine Etienne-Manneville, Stephanie Portet

Faculty Publications

Intermediate filaments are a key component of the cytoskeleton. Their trans- port along microtubules plays an essential role in the control of the shape and structural organization of cells. To identify the key parameters responsible for the control of intermediate filament transport, we generated a model of elastic filament transport by microtubule-associated dynein and kinesin. The model is also applicable to the transport of any elastically-coupled cargoes. We inves- tigate the effect of filament properties such as number of motor binding sites, length, and elasticity on motion of filaments. Additionally, we consider the ef- fect of motor properties, i.e. off …

Wasatch Front Atmospheric Deposition Reflects Regional Desert Dust And Local Anthropogenic Sources, Michael Max Goodman

Theses and Dissertations

Dust originating from dry lakes contributes harmful and toxic elements to downwind urban areas and mountain snowpack that is compounded by local contaminant inputs from anthropogenic sources. To evaluate dust contributions to an urban area from regional playas, we sampled playa dust sources, urban dust deposition, and snow dust deposition in central Utah, USA. Samples were analyzed for grain size, mineralogy, and chemistry. Bulk mineralogy between playa, urban, and snow dust samples was similar, with silicate, carbonate, and evaporite minerals. Grain size distribution between fine playa, urban, and snow dust particles was also similar. Elements found at high concentrations in …

Total Synthesis Of Anticancer Agent Deoxypodophyllotoxin And Antiviral F4-4 Demonstrating The Utility Of The Intramolecular Styryl Diels-Alder (Isda) Reaction, Diana Isabel Saavedra Nova

Theses and Dissertations

The intramolecular styryl Diels – Alder (ISDA) reaction is a rare and unique [4+2] cycloaddition with potential in the syntheses of polycycles. Its utility is based on the formation of two rings and one stereocenter in a single step, making it an efficient method for the construction of lignan-type natural product targets. Detailed mechanistic studies with complex esters and the application to natural product synthesis has been limited due to drawbacks including the loss of aromaticity, producing slow reactivity, a potentially problematic thermal [1,3]-hydrogen shift, and electronic mismatch related to the substituents on the aryl functional groups. In this research, …

Selective Catalysis By Polymer-Supported Ruthenium Nanoparticlesand New Ligand Design For Cooperative And Bimetallic Catalysis, Seyed Hadi Nazari

Theses and Dissertations

The abstract is the summary of three different projects all centered around the generalidea of catalysis which is the general theme of research in the Michaelis laboratory. The firstproject focuses on development of a new heterogeneous catalyst for selective catalysis. In theMichaelis lab, we were interested in the potential of nanoparticle catalysts for regioselectivetransformations. We showed that polymer supported ruthenium nanoparticles performed as areliable catalyst for regioselective reduction of azide to amine. In our study of regioselectivereduction of multiple azide containing substrates, we observed that in presence of ourruthenium nanoparticle catalysts, the least sterically hindered azide group reduced to aminefunctional …

Applications Of Pattern Recognition Entropy (Pre) And Informatics To Data Analysis, Shiladitya Chatterjee

Theses and Dissertations

The primary focus of my work is the application of informatics methods to the fields of materials science and analytical chemistry. The statistical analysis of data has become increasingly important in understanding the properties of materials and analytes. Statistical methods like principal component analysis (PCA) and multivariate curve resolution (MCR) are widely used for analysis in chemistry and other fields given their ability to categorize spectra in an unsupervised way. PCA is relatively easy to apply and has appealing mathematical properties. However, the results can be challenging to interpret, even for experienced users. In contrast, MCR results can be more …

Emergence Of Collective Behaviors In Hub-Based Colonies Using Grammatical Evolution And Behavior Trees, Aadesh Neupane

Theses and Dissertations

Animals such as bees, ants, birds, fish, and others are able to efficiently perform complex coordinated tasks like foraging, nest-selection, flocking and escaping predators without centralized control or coordination. These complex collective behaviors are the result of emergence. Conventionally, mimicking these collective behaviors with robots requires researchers to study actual behaviors, derive mathematical models, and implement these models as algorithms. Since the conventional approach is very time consuming and cumbersome, this thesis uses an emergence-based method for the efficient evolution of collective behaviors. Our method, Grammatical Evolution algorithm for Evolution of Swarm bEhaviors (GEESE), is based on Grammatical Evolution (GE) …

Schur Rings Over Infinite Groups, Cache Porter Dexter

Theses and Dissertations

A Schur ring is a subring of the group algebra with a basis that is formed by a partition of the group. These subrings were initially used to study finite permutation groups, and classifications of Schur rings over various finite groups have been studied. Here we investigate Schur rings over various infinite groups, including free groups. We classify Schur rings over the infinite cyclic group.

Using Coherence To Improve The Calculation Of Active Acoustic Intensity With The Phase And Amplitude Gradient Estimator Method, Mylan Ray Cook

Theses and Dissertations

Coherence, which gives the similarity of signals received at two microphone locations, can be a powerful tool for calculating acoustic quantities, particularly active acoustic intensity. To calculate active acoustic intensity, a multi-microphone probe is often used, and therefore coherence between all microphone pairs on the probe can be obtained. The phase and amplitude gradient estimator (PAGE) method can be used to calculate intensity, and is well suited for many situations. There are limitations to this method—such as multiple sources or contaminating noise in the sound field—which can cause significant error. When there are multiple sources or contaminating noise present, the …