Physical Sciences and Mathematics Commons^™

Ir Studies Of The Interaction Of Surfactants And Polyelectrolytes Adsorbed On Tio2 Particles, Haiyan Li

Electronic Theses and Dissertations

Polymers/surfactants are used to control and modify the interfacial properties of particulate suspensions. The resulting properties are dependent on the amount of adsorbed surfactants/polymers on the surface as well as the nature of the aggregated structures. Often these interactions are complex and not well understood. In this thesis we have used Attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) to identify surfactant, mixed surfactant, polyelectrolyte and mixed polyelectrolyte surfactant structures formed on charged Ti0₂ particles. In addition, the change occurring to the structure of an adsorbed polymer layer on Ti0₂ to flowing suspension of silica particles was studied. A …

9-Ethyl-3-Methyl-1, 6-Dinitrocarbazole, Erol Asker, John Masnovi

Chemistry Faculty Publications

No abstract provided.

Pyrrole Syntheses Based On Titanium-Catalyzed Hydroamination Of Diynes, Douglas Armstrong, Balasubramanian Ramanathan, Adam J. Keith, Aaron L. Odom

Faculty Scholarship – Chemistry

Titanium-catalyzed hydroamination of 1,4- and 1,5-diynes by primary amines leads to imino-alkynes that undergo in situ 5-endo dig and 5-exo dig cyclization reactions, respectively. The products are 1,2,5-trisubstituted pyrroles accessed directly from readily available diyne starting materials.

Solvent-Free Conversion Of Alpha-Naphthaldehyde To 1-Naphthoic Acid And 1-Naphthalenemethanol: Application Of The Cannizzaro Reaction, John J. Esteb, Keith M. Glogorich, Stacey A. O'Reilly

Scholarship and Professional Work - LAS

The Cannizzaro reaction is routinely covered in organic textbooks, but owing to the shortage of suitable procedures for the undergraduate teaching laboratory, this reaction is seldom performed in a first-year organic chemistry class. In this experiment, powdered potassium hydroxide and α-naphthaldehyde are heated under solvent-free conditions to produce 1-naphthoic acid and 1-naphthalenemethanol in 86% and 79% yields, respectively. The solvent-free nature of this procedure greatly reduces the quantity of waste generated by students relative to the typical solvent-based method of preparation. Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information …

Bismuth Compounds In Organic Synthesis. Bismuth Nitrate Catalyzed Chemoselective Synthesis Of Acylals From Aromatic Aldehydes, Ram Mohan, David Aggen, Joshua Arnold, Patrick Hayes, Nathaniel Smoter

Scholarship

Aromatic aldehydes are smoothly converted into the corresponding acylals in good yields in the presence of 3–10 mol% Bi(NO3)3•5H2O. Ketones are not affected under the reaction conditions. The relatively non-toxic nature of the catalyst, its ease of handling, easy availability and low cost make this procedure especially attractive for large-scale synthesis.

Environment-Friendly Organic Synthesis Using Bismuth Compounds. Bismuth Triflate Catalyzed Synthesis Of Substituted 3,4-Dihydro-2h-L-Benzopyrans, Ram Mohan, Mai Nguyen, Joshua Arnold, Katherine Peterson

Scholarship

A highly catalytic method for the synthesis of dihydrobenzopyrans from salicylaldehydes has been developed. An extension of this method to the synthesis of a pyrano [2,3,b]benzopyran has also been achieved. Bi(OTf)3.xH2O (1< x < 4) (0.1mol%) smoothly catalyzes the condensation of substituted salicylaldehydes with 2,2-dimethoxypropane to give the corresponding substituted 3,4-dihydro-2H-1-benzopyrans as a mixture of diastereomers (9:1) in moderate yields. The relative configuration of the methoxy groups in the two diastereomers was established by NOE experiments. The advantages of this method include the use of an easy to handle, inexpensive and relatively non-toxic catalyst.

Simple Epoxide Formation For The Organic Laboratory Using Oxone, John J. Esteb

Scholarship and Professional Work - LAS

We present an epoxide formation experiment for a second-semester organic chemistry laboratory. This oxidation utilizes Oxone, a commercially available oxidizing agent, in the industrially relevant process of epoxide formation. The oxidant performing the oxidation is dimethyldioxirane, which is formed in situ. This experiment demonstrates a simple synthesis of an epoxide and formation of a secondary oxidizing agent.

Cautionary Comments (Author Response), John J. Esteb, Anne M. Wilson

Scholarship and Professional Work - LAS

Reply to concerns about a safety factor in the paper, “A Solvent-Free Oxidation of Alcohols in an Organic Laboratory."

The Effects Of Multiple Mutations In The Hydrophobic Core Upon The Stability Of Staphylococcal Nuclease, Rebecca L. Danforth

Inquiry: The University of Arkansas Undergraduate Research Journal

Previous work in the laboratory of my research advisor, Dr. Wesley Stites, has investigated the core packing of the protein staphylococcal nuclease. The core of a protein is critical in determining a protein's structure and stability. The hydrophobicity of the core has long been thought to be the principal driving force for folding, but recent work in the Stites lab has shown that optimization of van der Waals contacts and minimization of cavities, in our shorthand term, packing, is at least as energetically important. We are building upon this information in our attempt to better pack the protein core. If …

2,2':6',2"-Terpyridine N,N',N"-Trioxide, Kraig A. Wheeler, Scott E. Mckay, Silas C. Blackstock

Kraig A. Wheeler

No abstract provided.

Semi-Biosynthesis Of Dna Nanostructures, Aoune Barhoumi

Theses, Dissertations and Capstones

Nanotechnology refers to all technologies aiming to build objects, make measurements, and carry out processes on the nanometer length scale. In particular molecular nanotechnology exemplifies the so-called "bottom up" approach, which is briefly defined as the ability to build useful nanostructures with molecular precision, such as molecular machinery. Such capability for controlling matter at the molecular scale has always been the dream of scientists.

All living things are nanofoundries. Billions of years ago, nature perfectly provided all living things with the most accurate biological nanotechnology systems. Cellular internal dynamics, communicative resonance in protein conformational states, viruses as microreplicators, nanoscale life …

Lipid-Lowering Effects Of Ethyl 2-Phenacyl-3-Aryl-1h-Pyrrole- 4-Carboxylates In Rodents, Justin M. Holub, Kathy O'Toole-Colin, Adam Getzel, Anthony Argenti, Michael A. Evans, Daniel C. Smith, Gerard A. Dalglish, Shahzad Rifat, Donna L. Wilson, Brett M, Taylor, Ulander Miott, Josephine Glersaye, Kam Suet Lam, Bryan J. Mccranor, Joshua D. Berkowitz, Robert B. Miller, John R. Lukens, Keith Krumpe, John T. Gupton, Bruce S. Burnham

Chemistry Faculty Publications

A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole derivatives proved to be potent hypolipidemic agents lowering serum triglyceride concentrations in CF-1 male mice after 14 days of I.P. administration. One agent orally lowered serum cholesterol in Sprague-Dawley male rats at 2mg/kg/day after 14 days. The agents demonstrated a lowering of mouse serum LDL- cholesterol levels and selected compounds showed an elevation of serum HDL-cholesterol levels. The cholesterol concentrations in the …

2,2':6',2"-Terpyridine N,N',N"-Trioxide, Kraig A. Wheeler, Scott E. Mckay, Silas C. Blackstock

Faculty Research and Creative Activity

No abstract provided.

Synthesis And Characterization Of Polyimide Residuum, Friable Balloons, Microspheres And Foams, Erik Saul Weiser

Dissertations, Theses, and Masters Projects

In order to meet requirements of future NASA systems for advanced polymeric cellular materials, research was undertaken to develop the next generation of polyimide foams which could be utilized as a reusable structural insulation on future Reusable Launch Vehicle (RLV) Programs. This research activity focused on developing polyimide foam and foam structures which were made using monomeric solutions or salt solutions formed from the reaction of a dianhydride and diamine dissolved in a mixture of foaming agents and alkyl alcohols. This process produced a precursor solid residuum which could then be manufactured into foams, friable balloons and microspheres. Polyimide foams …

Solvent-Free Conversion Of Alpha-Naphthaldehyde To 1-Naphthoic Acid And 1-Naphthalenemethanol: Application Of The Cannizzaro Reaction, John Esteb, Keith Gligorich, Stacy O'Reilly, Jeremy Richter

John Esteb

The Cannizzaro reaction is routinely covered in organic textbooks, but owing to the shortage of suitable procedures for the undergraduate teaching laboratory, this reaction is seldom performed in a first-year organic chemistry class. In this experiment, powdered potassium hydroxide and α-naphthaldehyde are heated under solvent-free conditions to produce 1-naphthoic acid and 1-naphthalenemethanol in 86% and 79% yields, respectively. The solvent-free nature of this procedure greatly reduces the quantity of waste generated by students relative to the typical solvent-based method of preparation. Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information …

Cautionary Comments (Author Response), John Esteb, Anne Wilson

John Esteb

Reply to concerns about a safety factor in the paper, “A Solvent-Free Oxidation of Alcohols in an Organic Laboratory."

Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information will be required for access. Users not affiliated with Butler University should contact their local librarian for assistance in locating a copy of this article.

Simple Epoxide Formation For The Organic Laboratory Using Oxone, John Esteb

John Esteb

We present an epoxide formation experiment for a second-semester organic chemistry laboratory. This oxidation utilizes Oxone, a commercially available oxidizing agent, in the industrially relevant process of epoxide formation. The oxidant performing the oxidation is dimethyldioxirane, which is formed in situ. This experiment demonstrates a simple synthesis of an epoxide and formation of a secondary oxidizing agent.

Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information will be required for access. Users not affiliated with Butler University should contact their local librarian for assistance in locating a copy of …

Environment-Friendly Organic Synthesis Using Bismuth Compounds. Bismuth Triflate Catalyzed Synthesis Of Substituted 3,4-Dihydro-2h-L-Benzopyrans, Ram S. Mohan, Mai P. Nguyen, Joshua N. Arnold, Katherine E. Peterson

Ram S. Mohan

Bismuth Compounds In Organic Synthesis. Bismuth Nitrate Catalyzed Chemoselective Synthesis Of Acylals From Aromatic Aldehydes, Ram S. Mohan, David H. Aggen, Joshua N. Arnold, Patrick D. Hayes, Nathaniel J. Smoter

Ram S. Mohan