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Full-Text Articles in Physical Sciences and Mathematics

In Silico Screeing Of Natural Compounds As Novel Drug Targets For Treatment Of Multiple Myeloma, Rousselene Larson Apr 2021

In Silico Screeing Of Natural Compounds As Novel Drug Targets For Treatment Of Multiple Myeloma, Rousselene Larson

Student Research Symposium

In Silico Screening of Natural Compounds as Novel Drug Targets for The Treatment of Multiple MyelomaRousselene Larson1 2, Naveen Duhan1, and Rakesh Kaundal1 2 *1Department of Plants, Soils, and Climate, College of Agriculture and Applied Sciences; 2Bioinformatics Facility, Center for Integrated BioSystems; Utah State University, Logan, UT 84322 USA* corresponding author (e-mail: rkaundal@usu.edu)Telephone: +1 (435) 797-4117Fax: +1 (435) 797-2766Abstract: Multiple Myeloma (MM) is an incurable hematological malignancy cancer characterized by excessive clonal plasma cell proliferation in the bone marrow. In the United States, MM is the second most prevalent type of cancer that affects about 4 in 100,000 Americans. Toxicity …


Comparative Study Of The Microbiome Of The Native Plant Ceanothus Velutinus (Snowbrush) From Different Locations And Greenhouse Studies, Jyothsna Ganesh Apr 2021

Comparative Study Of The Microbiome Of The Native Plant Ceanothus Velutinus (Snowbrush) From Different Locations And Greenhouse Studies, Jyothsna Ganesh

Student Research Symposium

Climatic change is one of the biggest threats to the ecosystem and biodiversity by enhancing environmental stresses. Environmental stresses such as biotic and abiotic stresses affect plant health and reduce crop production. The rhizosphere microbiome of a plant plays a significant role in a plant's defense against various biotic and abiotic stresses. In this study, we are investigating the microbiome diversity of bulk soil, rhizosphere, and endosphere of Ceanothus velutinus, snowbrush. Ceanothus is an evergreen native plant that is usually found in dry areas and thrives well in harsh conditions. The snowbrush samples were collected from different locations 1920m, 1950m, …


Day Versus Night Irrigation Loss From Sprinkler Irrigation Of Urban Crops, Samikshya Pyakurel Apr 2021

Day Versus Night Irrigation Loss From Sprinkler Irrigation Of Urban Crops, Samikshya Pyakurel

Student Research Symposium

Nighttime irrigation is a widespread strategy to conserve water, as it reduces wind drift and evaporation loss (WDEL). However, daytime sprinkler irrigation may also conserve water by lowering the temperature and increasing the humidity of crop microclimates, thereby reducing evapotranspiration (ET). Therefore, the objectives of this study include: 1) quantify whether a water savings exists between day and night irrigation with a water balance approach, 2) analyze the microclimate effects by irrigation timing to determine any changes to WDEL and evaporative demand, and 3) assess the quality and yield response of two urban crops. In 2019-21, we established 12 field …


Transgenic Expression Of Prunus Persica Salt Overly Sensitive 2 (Ppsos2) In Atsos2 Mutant Imparts Salt Tolerance In Arabidopsis, Vishal Singh Apr 2021

Transgenic Expression Of Prunus Persica Salt Overly Sensitive 2 (Ppsos2) In Atsos2 Mutant Imparts Salt Tolerance In Arabidopsis, Vishal Singh

Student Research Symposium

Salinity is one of the major environmental stresses that affect crop growth and productivity. Almond crop has a great potential for Utah as a cash crop and salinity is one of the stresses affecting its growth and yield. Although almond trees are sensitive to salt stress, salinity-tolerant rootstocks can play a significant role in sustaining crop production in semiarid areas. Salinity tolerance has a complex mechanism with many genes acting in different pathways. Understanding the role of potential candidate genes is an important aspect of genomics assisted improvement of stress tolerance. In this study, functional complementation of the Prunus persica …


Genomic Prediction Of Salinity Stress Tolerance In Maize (Zea Mays L.), Vishal Singh Apr 2021

Genomic Prediction Of Salinity Stress Tolerance In Maize (Zea Mays L.), Vishal Singh

Student Research Symposium

Maize is the largest crop in the world in terms of production. Utah, maize is a potential fodder crop. With increasing climate change, soil salinity is also increasing worldwide. Soil salinity is very detrimental to plants' growth and development and crop production. For a fodder crop, plant biomass is an important trait, and maize biomass is adversely affected by salinity stress, especially at the seedling stage. A Selection of salt-tolerant breeding material is a time-consuming process and its complexity is further increased by significant heterogeneity in soil salinity under field based evaluation. Genomic prediction is an emerging tool that can …


Microbial Community Of The Rhizosphere Of Ceanothus Velutinus Improves The Plant's Growth And Development Under Greenhouse Conditions, Jyothsna Ganesh Apr 2021

Microbial Community Of The Rhizosphere Of Ceanothus Velutinus Improves The Plant's Growth And Development Under Greenhouse Conditions, Jyothsna Ganesh

Student Research Symposium

Climatic change-induced environmental stresses affect crop production. Drought is such a stress which affect crop production and landscaping adversely. Native plants are great for low water use landscaping and can adapt to the natural environment. USU Center for Water-Efficient Landscaping has released a list of native plants that can be used for this purpose. This study focuses on a native plant Ceanothus velutinus (snowbrush) which is an evergreen plant native to western North America. It thrives well in harsh conditions and can act as ornamental plant in low water use landscaping but is difficult to propagate under landscape conditions. Here, …


Deepnec: A Novel Alignment-Free Tool For The Characterization Of Nitrification-Related Enzymes Using Deep Learning, A Step Towards Comprehensive Understanding Of The Nitrogen Cycle, Naveen Duhan Apr 2021

Deepnec: A Novel Alignment-Free Tool For The Characterization Of Nitrification-Related Enzymes Using Deep Learning, A Step Towards Comprehensive Understanding Of The Nitrogen Cycle, Naveen Duhan

Student Research Symposium

Abstract: Nitrification is an important microbial two-step transformation in the global nitrogen cycle, as it is the only natural process that produces nitrate within a system. The functional annotation of nitrification-related enzymes has a broad range of applications in metagenomics, agriculture, industrial biotechnology, etc. The time and resources needed for determining the function of enzymes experimentally are restrictively costly. Therefore, an accurate genome-scale computational prediction of the nitrification-related enzymes has become much more important.In this study, we developed an alignment-free computational approach to determine the nitrification-related enzymes from the sequence itself. We propose deepNEC, a novel end-to-end feature selection and …


Pyseqrna: An Automated Python Package For Advanced Rna Sequencing Data Analysis And Annotation, Naveen Duhan Apr 2021

Pyseqrna: An Automated Python Package For Advanced Rna Sequencing Data Analysis And Annotation, Naveen Duhan

Student Research Symposium

Abstract: With the advent of Next-Generation Sequencing (NGS) technologies, numerous data is being generated every day, however, streamlined analysis remains a big hurdle to efficiently use the technology. A large number of algorithms, statistical methods, and software tools have been developed in recent years to perform the individual analysis steps of various NGS applications. Some NGS applications data analysis procedures are therefore very complex, requiring several program tools to be downloaded for their various processing steps. There is a significant room for the development of scalable computing environments that link the individual software components to automated workflows to efficiently and …


Nitrogen Use Efficiency And Soil Bioavailable Nitrogen In Corn Silage Production In A Semi-Arid Environment, Phearen Miller Apr 2021

Nitrogen Use Efficiency And Soil Bioavailable Nitrogen In Corn Silage Production In A Semi-Arid Environment, Phearen Miller

Student Research Symposium

As agriculture intensifies, the world faces a dual challenge of increasing food production while reducing impacts of excess reactive nitrogen (N) in the environment. A field study examining different N sources in corn silage under semi-arid conditions was conducted at the Greenville farm in northern Utah (41°45’ N, 1111°48’52 W) since 2012. The experimental design is a randomized complete block design with four blocks and four treatments: control (no nitrogen), low ammonium sulfate (AS 112 kg N/ha), high ammonium sulfate (AS 224 kg N/ha), and steer manure compost (224 kg total N/ha). We examined yield, nitrogen use efficiency (NUE), and …