Physical Sciences and Mathematics Commons^™

Video Feature — Banned Books And The Stuart Rose Collection, Robert Brecha, Una Cadegan, John Inglis, Paul Morman

John A. Inglis

A faculty panel discussion in two sessions:

Session 1:
The Index: Una Cadegan (history) looks at the current scholarship on the Index of Forbidden Books.
Galileo: Robert Brecha (physics) highlights the banning of Galileo and observational science.

Session 2:
Thomas Aquinas: John Inglis (philosophy) speaks on the banning of Thomas Aquinas's Summa Theologica, the most important book in Catholic intellectual tradition.
Descartes and the Index of Forbidden Books: Paul Morman (history, Distinguished Service Professor) highlights the book by Descartes that he was not allowed to study while a student at UD in the 1960s.

Video Feature — Banned Books And The Stuart Rose Collection, Robert Brecha, Una Cadegan, John Inglis, Paul Morman

Robert J. Brecha

A faculty panel discussion in two sessions:

Session 1:
The Index: Una Cadegan (history) looks at the current scholarship on the Index of Forbidden Books.
Galileo: Robert Brecha (physics) highlights the banning of Galileo and observational science.

Session 2:
Thomas Aquinas: John Inglis (philosophy) speaks on the banning of Thomas Aquinas's Summa Theologica, the most important book in Catholic intellectual tradition.
Descartes and the Index of Forbidden Books: Paul Morman (history, Distinguished Service Professor) highlights the book by Descartes that he was not allowed to study while a student at UD in the 1960s.

Exhibition Catalogue — Imprints And Impressions: Milestones In Human Progress, Paul H. Benson, Sandra A. Yocum, Mark Masthay, Donald J. Polzella

Donald J. Polzella

Exhibition catalogue for Imprints and Impressions: Milestones in Human Progress — Highlights from the Rose Rare Book Collection. Includes an introduction by Kathleen M. Webb, dean of University Libraries; essays about the impact of the exhibition's books on modern inquiry, the humanities, the sciences, and the social sciences; and photographs of the works in the exhibit.

Rare Books And Social Science, Donald J. Polzella

Donald J. Polzella

An essay on the impact of the works in the Imprints and Impressions: Milestones in Human Progress, an exhibition of rare books from the collection of Stuart Rose. Exhibition was held Sept. 29-Nov. 9, 2014, at the University of Dayton.

Exhibition Catalogue — Imprints And Impressions: Milestones In Human Progress, Paul H. Benson, Sandra A. Yocum, Mark Masthay, Donald J. Polzella

Paul H. Benson

Exhibition catalogue for Imprints and Impressions: Milestones in Human Progress — Highlights from the Rose Rare Book Collection. Includes an introduction by Kathleen M. Webb, dean of University Libraries; essays about the impact of the exhibition's books on modern inquiry, the humanities, the sciences, and the social sciences; and photographs of the works in the exhibit.

Science Classics, Mark Masthay

Mark Masthay

An essay on the impact of the works in the Imprints and Impressions: Milestones in Human Progress, an exhibition of rare books from the collection of Stuart Rose. Exhibition was held Sept. 29-Nov. 9, 2014, at the University of Dayton.

Exhibition Catalogue — Imprints And Impressions: Milestones In Human Progress, Paul H. Benson, Sandra A. Yocum, Mark Masthay, Donald J. Polzella

Mark Masthay

Exhibition catalogue for Imprints and Impressions: Milestones in Human Progress — Highlights from the Rose Rare Book Collection. Includes an introduction by Kathleen M. Webb, dean of University Libraries; essays about the impact of the exhibition's books on modern inquiry, the humanities, the sciences, and the social sciences; and photographs of the works in the exhibit.

Development Of A Novel Screening Strategy Designed To Discover A New Class Of Hiv Drugs, Nancy Cheng, Sook-Kyung Lee, P. Donover, Mel Reichman, Celia Schiffer, Emily Hull-Ryde, Ronald Swanstrom, William Janzen

Celia A. Schiffer

Current antiretroviral treatments target multiple pathways important for human immunodeficiency virus (HIV) multiplication, including viral entry, synthesis and integration of the DNA provirus, and the processing of viral polyprotein precursors. However, HIV is becoming increasingly resistant to these "combination therapies." Recent findings show that inhibition of HIV Gag protein cleavage into its two structural proteins, matrix (MA) and capsid (CA), has a devastating effect on viral production, revealing a potential new target class for HIV treatment. Unlike the widely used HIV protease inhibitors, this new class of inhibitor would target the substrate, not the protease enzyme itself. This approach offers …

Wonder-Worlds Of Words, Sandra A. Yocum

Sandra A. Yocum

An essay on the impact of the works in the Imprints and Impressions: Milestones in Human Progress, an exhibition of rare books from the collection of Stuart Rose. Exhibition was held Sept. 29-Nov. 9, 2014, at the University of Dayton.

Exhibition Catalogue — Imprints And Impressions: Milestones In Human Progress, Paul H. Benson, Sandra A. Yocum, Mark Masthay, Donald J. Polzella

Sandra A. Yocum

Exhibition catalogue for Imprints and Impressions: Milestones in Human Progress — Highlights from the Rose Rare Book Collection. Includes an introduction by Kathleen M. Webb, dean of University Libraries; essays about the impact of the exhibition's books on modern inquiry, the humanities, the sciences, and the social sciences; and photographs of the works in the exhibit.

Exhibition Handlist, Kathleen M. Webb

Kathleen M. Webb

In preparing for Imprints and Impressions, we ran across many interesting words that have fallen out of the general lexicon. With this booklet, we have brought one back: handlist. Dean Kathleen Webb ran across it in a 1944 booklet from the J. Pierpont Morgan Library in New York City. Though the word no longer appears in most new dictionaries, it’s still in the Oxford English Dictionary: A list of a particular type or category of things, presented in a readily consultable form; esp. a list of the books or manuscripts in a particular place, on a particular subject, etc.; a …

Real-Time Mri-Guided Catheter Tracking Using Hyperpolarized Silicon Particles, Nicholas Whiting, Jingzhe Hu, Jay V. Shah, Maja C. Cassidy, Erik Cressman, Niki Zacharias Millward, David G. Menter, Charles M. Marcus, Pratip K. Bhattacharya

Nicholas Whiting

Flow Of Dna Solutions In A Microfluidic Gradual Contraction, Shelly Gulati, Susan J. Muller, Dorian Liepmann

Shelly Gulati

Cefepime Neurotoxicity In An Adolescent Cystic Fibrosis Patient With Aminoglycoside-Induced Acute Kidney Injury, Kristen R. Nichols, Danielle M. Brown, Chad A. Knoderer, Sharon P. Andreoli

Kristen R. Nichols

Objective: To describe a case of cefepime neurotoxicity in an adolescent with cystic fibrosis and aminoglycoside-associated acute kidney injury (AKI).

Case Summary: A 15-year-old, 46-kg male with cystic fibrosis (CF) and chronic sinusitis was admitted to the hospital for CF exacerbation. The patient was subsequently discharged to complete home antibiotic therapy with intravenous gentamicin and cefepime. Thirteen days after discharge, while still receiving intravenous antibiotics, the patient presented to an outside hospital complaining of vomiting, fatigue, decreased appetite, and decreased urine output. The patient was diagnosed with AKI and was transferred to our institution, where he displayed signs and symptoms …

Implantable Polymer/Metal Thin Film Structures For The Localized Treatment Of Cancer By Joule Heating, Nima Rahbar, Kwabena Kan-Dapaah, Christian Theriault, Wole Soboyejo

Nima Rahbar

This paper presents an implantable polymer/metal alloy thin film structure for localized post-operative treatment of breast cancer. A combination of experiments and models is used to study the temperature changes due to Joule heating by patterned metallic thin films embedded in poly-dimethylsiloxane. The heat conduction within the device and the surrounding normal/cancerous breast tissue is modeled with three-dimensional finite element method (FEM). The FEM simulations are used to explore the potential effects of device geometry and Joule heating on the temperature distribution and lesion (thermal dose). The FEM model is validated using a gel model that mimics biological media. The …

Multistrain Infections In Metapopulations, Sydney Garmer, Rachel Lynn, Dan Rossi, Alex Capaldi

Alex Capaldi

Case Studies In Evaluating Time Series Prediction Models Using The Relative Mean Absolute Error, Nicholas G. Reich, Justin Lessler, Krzysztof Sakrejda, Stephen A. Lauer, Sopon Iamsirithaworn, Derek A T Cummings

Nicholas G Reich

Statistical prediction models inform decision-making processes in many real-world settings. Prior to using predictions in practice, one must rigorously test and validate candidate models to ensure that the proposed predictions have sufficient accuracy to be used in practice. In this paper, we present a framework for evaluating time series predictions that emphasizes computational simplicity and an intuitive interpretation using the relative mean absolute error metric. For a single time series, this metric enables comparisons of candidate model predictions against naive reference models, a method that can provide useful and standardized performance benchmarks. Additionally, in applications with multiple time series, this …

Use Of Geographical Information Systems To Identify Counties In Georgia With High Risk For Childhood Lead Poisoning, R. Christopher Rustin, Christy Kuriatnyk, Byron Lobsinger, Simone Charles

R. Christopher Rustin

Spin-Exchange Optical Pumping At High Xenon Densities And Laser Fluxes: Principles And Practice, Boyd M. Goodson, Nicholas Whiting, Hayley Newton, Jason G. Skinner, Kaili Ranta, Panayiotis Nikolaou, Michael J. Barlow, Eduard Y. Chekmenev

Nicholas Whiting

Hyperpolarization Methods For Mrs, Boyd M. Goodson, Nicholas Whiting, Aaron M. Coffey, Panayiotis Nikolaou, Fan Shi, Brogan M. Gust, Maxwell E. Gemeinhardt, Roman Shchepin, Jason G. Skinner, Jonathan R. Birchall, Michael J. Barlow, Eduard Y. Chekmenev

Nicholas Whiting

Quantile Rank Maps: A New Tool For Understanding Individual Brain Development, Huaihou Chen, Clare Kelly, F. Xavier Castellanos, Ye He, Xi-Nian Zuo, Philip T. Reiss

Philip T. Reiss

We propose a novel method for neurodevelopmental brain mapping that displays how an individual’s values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be …

Cross-Validation And Hypothesis Testing In Neuroimaging: An Irenic Comment On The Exchange Between Friston And Lindquist Et Al., Philip T. Reiss

Philip T. Reiss

The “ten ironic rules for statistical reviewers” presented by Friston (2012) prompted a rebuttal by Lindquist et al. (2013), which was followed by a rejoinder by Friston (2013). A key issue left unresolved in this discussion is the use of cross-validation to test the significance of predictive analyses. This note discusses the role that cross-validation-based and related hypothesis tests have come to play in modern data analyses, in neuroimaging and other fields. It is shown that such tests need not be suboptimal and can fill otherwise-unmet inferential needs.

Epidemiology Of Latency And Relapse In Plasmodium Vivax Malaria, Andrew A. Lover

Andrew Lover

Considerations For Comprehensive Analyses Of Sporozoite-Based Controlled Human Malaria Infection Studies, Andrew A. Lover

Andrew Lover

Short Report: Study Variability In Recent Human Challenge Experiments With Plasmodium Falciparum Sporozoites (Pfspz Challenge), Andrew A. Lover

Andrew Lover