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2016

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Full-Text Articles in Physical Sciences and Mathematics

Evolution In The Deep Sea: Scales And Mechanisms Of Population Divergence, Amanda E. Glazier Dec 2016

Evolution In The Deep Sea: Scales And Mechanisms Of Population Divergence, Amanda E. Glazier

Graduate Doctoral Dissertations

The deep sea is the Earth’s largest ecosystem and harbors a unique and largely endemic fauna. Although most research has focused on the ecological mechanisms that allow coexistence, recent studies have begun to investigate how this remarkable fauna evolved.. My work quantifies geographic patterns of genetic variation and investigates potential mechanisms that shape evolution in the deep ocean.

Bathymetric genetic divergence is common in the deep sea with population structure typically decreasing with depth. The evolutionary mechanisms that underlie these patterns are poorly understood. Geographic patterns of genetic variation indicated that the protobranch bivalve Neilonella salicensis was composed of two …


U.S. Drought Monitor, December 27, 2016, Brad Rippey Dec 2016

U.S. Drought Monitor, December 27, 2016, Brad Rippey

United States Agricultural Commodities in Drought Archive

Drought map of U.S. for December 27, 2016 (12/27/16) plus: U.S. crop areas experiencing drought (map), Approximate percentage of crop located in drought, by state (bar graph), Percent of crop area located in drought, past 52 weeks (line graph) for: Corn, Soybeans, Hay, Cattle, Winter wheat.


Novel Models Of Visual Topographic Map Alignment In The Superior Colliculus., Ruben A Tikidji-Hamburyan, Tarek A El-Ghazawi, Jason W. Triplett Dec 2016

Novel Models Of Visual Topographic Map Alignment In The Superior Colliculus., Ruben A Tikidji-Hamburyan, Tarek A El-Ghazawi, Jason W. Triplett

Pediatrics Faculty Publications

The establishment of precise neuronal connectivity during development is critical for sensing the external environment and informing appropriate behavioral responses. In the visual system, many connections are organized topographically, which preserves the spatial order of the visual scene. The superior colliculus (SC) is a midbrain nucleus that integrates visual inputs from the retina and primary visual cortex (V1) to regulate goal-directed eye movements. In the SC, topographically organized inputs from the retina and V1 must be aligned to facilitate integration. Previously, we showed that retinal input instructs the alignment of V1 inputs in the SC in a manner dependent on …


2016, Sep. 22 -- Bulletin 118, Interim Update 2016, California's Groundwater Working Toward Sustainability, Dwr Dec 2016

2016, Sep. 22 -- Bulletin 118, Interim Update 2016, California's Groundwater Working Toward Sustainability, Dwr

State and Federal Documents Relating to Monterey and San Luis Obispo Counties

The purpose of the interim update to Bulletin 118 is to provide up-to-date information on California groundwater basins subject to critical conditions of overdraft, groundwater basin boundaries, and basin prioritization. The information is essential to the successful implementation of the Sustainable Groundwater Management Act passed in 2014 (SGMA), including the timely formation of groundwater sustainability agencies and the development of groundwater sustainability plans.


Bioremoval Of Phenol From Aqueous Solutions Using Native Caribbean Seaweed, Abel E. Navarro, Anibal Hernandez-Vega, Md Emran Masud, Loretta M. Roberson, Liz M. Diaz-Vázquez Dec 2016

Bioremoval Of Phenol From Aqueous Solutions Using Native Caribbean Seaweed, Abel E. Navarro, Anibal Hernandez-Vega, Md Emran Masud, Loretta M. Roberson, Liz M. Diaz-Vázquez

Publications and Research

Among several Puerto Rican algae, Sargassum sp. (SG) and Chaetomorpha (CM) showed the highest phenol adsorption capacity from aqueous solutions and were used in optimized adsorption batch experiments at room temperature. The effects of pH, adsorbent dose, phenol concentration, salinity and presence of interfering substances were evaluated. Initial solution pH exhibited a strong effect, mainly on the phenol aqueous chemistry; showing the maximum adsorption at pH 10. Sorption isotherm results were modelled according to the Langmuir, Tempkin and Freundlich equations. Isotherm modelling indicated a maximum adsorption capacity (qmax) of 82.10 and 17.7 mg of phenol per gram of SG and …


The Chemistry Of The Flint Water Crisis, Ernest M. Oleksy Dec 2016

The Chemistry Of The Flint Water Crisis, Ernest M. Oleksy

The Downtown Review

Politics and science do not always go hand-in-hand. Nowhere was this more clear than in the Flint Water Crisis. Negligence towards growing levels of lead poisoning in drinking water led to incredibly deleterious effects on Flint's citizens. The chemistry of equilibrium and the shortcomings of local leaders led to Flint's water becoming a crisis.


Myofilament Calcium Sensitivity: Consequences Of The Effective Concentration Of Troponin I, Jalal K. Siddiqui, Svetlana B. Tikunova, Shane D. Walton, Bin Liu, Meredith Meyer, Pieter P. De Tombe, Nathan Neilson, Peter M. Kekenes-Huskey, Hussam E. Salhi, Paul M.L. Janssen, Brandon J. Biesiadecki, Jonathan P. Davis Dec 2016

Myofilament Calcium Sensitivity: Consequences Of The Effective Concentration Of Troponin I, Jalal K. Siddiqui, Svetlana B. Tikunova, Shane D. Walton, Bin Liu, Meredith Meyer, Pieter P. De Tombe, Nathan Neilson, Peter M. Kekenes-Huskey, Hussam E. Salhi, Paul M.L. Janssen, Brandon J. Biesiadecki, Jonathan P. Davis

Chemistry Faculty Publications

Control of calcium binding to and dissociation from cardiac troponin C (TnC) is essential to healthy cardiac muscle contraction/relaxation. There are numerous aberrant post-translational modifications and mutations within a plethora of contractile, and even non-contractile, proteins that appear to imbalance this delicate relationship. The direction and extent of the resulting change in calcium sensitivity is thought to drive the heart toward one type of disease or another. There are a number of molecular mechanisms that may be responsible for the altered calcium binding properties of TnC, potentially the most significant being the ability of the regulatory domain of TnC to …


A Mineralized Alga And Acritarch Dominated Microbiota From The Tully Formation (Givetian) Of Pennsylvania, Usa, John A. Chamberlain Jr., Rebecca B. Chamberlain, James O. Brown Dec 2016

A Mineralized Alga And Acritarch Dominated Microbiota From The Tully Formation (Givetian) Of Pennsylvania, Usa, John A. Chamberlain Jr., Rebecca B. Chamberlain, James O. Brown

Publications and Research

Sphaeromorphic algal cysts, most probably of the prasinophyte Tasmanites, and acanthomorphic acritarch vesicles, most probably Solisphaeridium, occur in a single 20 cm thick bed of micritic limestone in the lower part of the Middle Devonian (Givetian) Tully Formation near Lock Haven, Pennsylvania. Specimens are composed of authigenic calcite and pyrite crystals about 5–10 µm in length. Some specimens are completely calcitic; some contain both pyrite and calcite; and many are composed totally of pyrite. The microfossils are about 80 to 150 µm in diameter. Many show signs of originally containing a flexible wall composed of at least two layers. Some …


Impacts Of Long-Term Precipitation Manipulation On Hydraulic Architecture, Xylem Function, And Canopy Status In A Piñon-Juniper Woodland, Patrick J. Hudson Dec 2016

Impacts Of Long-Term Precipitation Manipulation On Hydraulic Architecture, Xylem Function, And Canopy Status In A Piñon-Juniper Woodland, Patrick J. Hudson

Biology ETDs

The Southwestern US is predicted to become hotter and drier, as global climate change forces increasing temperatures and variability in timing and size of precipitation inputs. Drought stress has become more frequent in recent decades, and resulted in massive forest mortality in piñon-juniper woodlands. During recent severe droughts (2000-2003, 2009-2012), piñon pine (Pinus edulis Englem.) suffered disproportionately high mortality compared to co-occurring one-seed juniper (Juniperus monosperma [Engelm.] Sarg.). A large-scale precipitation manipulation experiment was established in a piñon-juniper woodland in central New Mexico to test hypotheses regarding tree survival and mortality with respect to altered water regimes. Our …


Flight Of The Freshwater Fish, Michael H. Wilson Dec 2016

Flight Of The Freshwater Fish, Michael H. Wilson

Capstones

Michael H. Wilson

Capstone Abstract

December 27, 2016

Flight of the Freshwater Fish

The Hudson River provides for millions of people as a path for commercial and private transportation, a source of food and energy, and perhaps most importantly for many living in the tri-state area as a destination for recreation and relaxation. The most overlooked feature of the river is how the wildlife shows clear signs of a changing climate and rapid environmental response to the impacts of global warming on the river.

Entire populations of fish species in the lower Hudson have been forced to leave the river …


An Analysis Of Gulf Of Maine Cod Metapopulation Structure And Localized Stability, With Application To Area-Based Fisheries Management, Derek Olson Dec 2016

An Analysis Of Gulf Of Maine Cod Metapopulation Structure And Localized Stability, With Application To Area-Based Fisheries Management, Derek Olson

Electronic Theses and Dissertations

The complex metapopulation structure of groundfish stocks in the Gulf of Maine, particularly Atlantic cod (Gadus morhua), is largely ignored under the current system of broad-scale stock assessment and management. This mismatch of biological and administrative scales has contributed to severe overall stock decline and localized serial depletion of Gulf of Maine cod. Such chronic management failure has led to growing calls for a more area-based, finer-scale approach to managing groundfish in the Gulf of Maine. A primary difficulty hindering the development of finer-scale groundfish management has been the challenge of estimating fishing mortality upon local stock components. …


Roles Of Siphon Flows In Suspension Feeding, Kevin Du Clos Dec 2016

Roles Of Siphon Flows In Suspension Feeding, Kevin Du Clos

Electronic Theses and Dissertations

Benthic marine suspension feeders provide an important link between benthic and pelagic ecosystems. The strength of this link is determined by suspension-feeding rates. Many studies have measured suspension-feeding rates using indirect clearance-rate methods, which are based on the depletion of suspended particles. Direct methods that measure the flow of water itself are less common, but they can be more broadly applied because clearance-rate measurements are affected by properties of the cleared particles. We present pumping rates for three species of suspension feeders, the clams Mya arenaria and Mercenaria mercenaria and the tunicate Ciona intestinalis, calculated using a direct method …


An Assessment Of Data Related To Inspections Of Risk Factors For Public Swimming Pools, Shanita Shack, Maurice Redmond, R. Christopher Rustin Dec 2016

An Assessment Of Data Related To Inspections Of Risk Factors For Public Swimming Pools, Shanita Shack, Maurice Redmond, R. Christopher Rustin

Environmental Health Sciences Faculty Publications

Background: The Georgia Department of Public Health (DPH) is mandated to ensure that public swimming pools are safe for those who use them. This mandate is carried out by the DPH and local environmental health professionals through regulations and inspections. In 2015, legislation was introduced proposing to reduce the authority of the DPH to inspect certain pool types (apartments, subdivision, condominiums) and thus reduce regulatory protections in place for swimmers. To ensure that the DPH had current information on the risks associated with pools, the EH team, with assistance from a graduate student, analyzed inspection data to evaluate risk factors …


A Preliminary Examination Of Elevated Blood Lead Levels In A Rural Georgia County, R. Christopher Rustin, Yu Sun, Chris Calhoun, Christy Kuriatnyk Dec 2016

A Preliminary Examination Of Elevated Blood Lead Levels In A Rural Georgia County, R. Christopher Rustin, Yu Sun, Chris Calhoun, Christy Kuriatnyk

Environmental Health Sciences Faculty Publications

Background: Rural areas are often viewed as lower risk for lead poisoning and toxic exposures seriously impacting development of the brain and central nervous system; this report examines the prevalence of elevated blood lead levels for children <6 years of age in rural Ben Hill County, GA.

Methods: Lead surveillance data from the Georgia Department of Public Health (DPH) were analyzed using SAS®v-9.3 to calculate the prevalence of elevated blood lead levels (≥5ug/dL) among those children in Ben Hill County who had been tested for lead; the results were compared to Georgia and national data.

Results: A preliminary analysis of 2010-2015 screening data for Ben Hill County indicates that 8.73% …


Sea Level Change In The Gulf Islands National Park Reserve, Southern British Columbia: Implications For The Interpretation Of Nearshore Archaeological Features, Glenda J. Wyatt Dec 2016

Sea Level Change In The Gulf Islands National Park Reserve, Southern British Columbia: Implications For The Interpretation Of Nearshore Archaeological Features, Glenda J. Wyatt

Salish Sea Ecosystem Conference

Sea level along the B.C. coastline has changed dramatically over the past 10,000 years due to isostatic rebound following deglaciation from the Fra ser Glaciation (Clague & James, 2002). In the future, sea levels globally are also predicted to rise according to the Intergovernmental Panel on Climate Change (IPCC) (2014), due to climate change. Lemmen et al. (2008), suggest that in the near future some B.C. coastal communities will have to deal with changes in shorelines due to rising sea levels, and hence erosional patterns, modifications to ecosystems and habitats, and potentially an altered marine food supply. This thesis examines …


Pacific Great Blue Heron Population Monitoring On Vancouver Island And The Surrounding Gulf Islands, Trudy A. Chatwin, Travis Heckford Dec 2016

Pacific Great Blue Heron Population Monitoring On Vancouver Island And The Surrounding Gulf Islands, Trudy A. Chatwin, Travis Heckford

Salish Sea Ecosystem Conference

The Pacific or Great Blue Heron fannini subspecies winters and breeds on Vancouver Island in locations within 5 km of the marine shoreline. Its visibility and close connection to the Salish Sea make it an important flagship species. Due to population concerns and threats associated with urban development, the Province of BC has coordinated monitoring of Great Blue Heron colonies on Vancouver Island and the adjacent Gulf Islands from 1997 through 2015. Starting in 2005, I trained volunteer stewards and technicians to use a standardized methodology to locate and assess heron colonies, count active nests, determine nest success and follow …


Vitamin E Circular Dichroism Studies: Insights Into Conformational Changes Induced By The Solvent’S Polarity, Drew Marquardt, Brad J. Van Oosten, Mikel Ghelfi, Jeffrey Atkinson, Thad A. Harroun Dec 2016

Vitamin E Circular Dichroism Studies: Insights Into Conformational Changes Induced By The Solvent’S Polarity, Drew Marquardt, Brad J. Van Oosten, Mikel Ghelfi, Jeffrey Atkinson, Thad A. Harroun

Chemistry and Biochemistry Publications

We used circular dichroism (CD) to study differences in CD spectra between α-, δ-, and methylated-α-tocopherol in solvents with different polarities. CD spectra of the different tocopherol structures differ from each other in intensity and peak locations, which can be attributed to chromanol substitution and the ability to form hydrogen bonds. In addition, each structure was examined in different polarity solvents using the Reichardt index—a measure of the solvent’s ionizing ability, and a direct measurement of solvent–solute interactions. Differences across solvents indicate that hydrogen bonding is a key contributor to CD spectra at 200 nm. These results are a first …


The Evolution Of Zero-Tolerance Policies, Stephanie D. Stahl Dec 2016

The Evolution Of Zero-Tolerance Policies, Stephanie D. Stahl

CrissCross

Most Americans today have a largely negative image of zero-tolerance policies (ZTP) enacted to stop and prevent violence in the United States school system. According to the U.S. Department of Education Office of Educational Research and Improvement, zero-tolerance procedures are policies that mandate predetermined consequences or punishments for specific offenses (Walker). These policies specifically targeted actions considered violent and threatening, such as possession of a firearm or weapon. The concept of zero-tolerance policies was introduced into the education system during the 1980s as part of the failed War on Drugs as an attack on drug usage and violence in schools. …


The Labyrinth Of The Mind: The Psychology Of War Stories In Tim O’Brien’S Going After Cacciato, Rebekah Smith Dec 2016

The Labyrinth Of The Mind: The Psychology Of War Stories In Tim O’Brien’S Going After Cacciato, Rebekah Smith

CrissCross

This paper explores and analyzes the psychological reasons for storytelling by soldiers and veterans both during and after their deployments in war. It brings in multiple works by author-veterans as well as critical writing about these books with a specific focus on Going After Cacciato by Tim O'Brien. Paul Berlin, the novel's protagonist, imagines a fictional quest leaving Vietnam and going all the way to Paris following the desertion of a fellow soldier gone AWOL. He creates this journey to create order, find meaning, generate understanding, and focus on the good rather than the bad. This paper also explores the …


American Spring, Sam Mullooly, Tom Mullooly Dec 2016

American Spring, Sam Mullooly, Tom Mullooly

CrissCross

Composer's Notes

I composed American Spring during the 2015-2016 school year, my final year as an undergraduate at Illinois Wesleyan University, in connection with the 150th anniversary of the end of the Civil War. This opera takes place mostly in April 1865, the year Richmond burned and Lincoln died, and deals with America’s feelings of pride and shame in war. The opera’s main character is Varina Davis, the wife of confederate President Jefferson Davis. Varina offers the 1860’s Southern perspective on slavery and the war, one glossed over in most readings of our history because it is so obviously repugnant …


Birthing Center Versus Hospitalized Birth, Nicolette Larsen Dec 2016

Birthing Center Versus Hospitalized Birth, Nicolette Larsen

CrissCross

There are many risks and benefits of giving birth at a birthing center versus a hospital. Determining the location of birth is an important decision, as women in the world today have many options of where to have their child. Hospitals and birthing centers are two places where medical professionals provide prenatal, labor and delivery, and postpartum care for the mother and fetus during this memorable time. While hospital nurses and physicians provide advanced medical care, birthing centers focus on holistic care of the family unit emphasizing mental, spiritual, and physical health. Doctors often perform cesarean sections (C-sections) for non-medical …


A Park Story, David Flowers, Evan Dolan Dec 2016

A Park Story, David Flowers, Evan Dolan

CrissCross

Composer's Note

A Park Story was written to be an honest and objective portrayal of the struggles that both characters experience throughout their collective story. Christopher and his mother both end up fighting two dominating perspectives of their identity: their family roles, and how they identify themselves. Their self-identities collide with each other in an irreconcilable manner; while both of them strongly desire the family bond they have, the mother’s convictions become the line that neither of them have any desire to cross.



Tracking The Elephant (Lexodonta Africana) Corridor And The Human-Wildlife Conflict In Selela Village, Nicole Chlebek, Laura Stalter Dec 2016

Tracking The Elephant (Lexodonta Africana) Corridor And The Human-Wildlife Conflict In Selela Village, Nicole Chlebek, Laura Stalter

CrissCross

The beastly journey of long-distance migration for the African Elephant (Lexodonta Africana) is important for upholding their connections between diminishing protected areas, especially in northeastern Tanzania. However, human development is encroaching into these corridors, creating a human-elephant conflict, which can ruin livelihoods of villagers, depending on the extent of conflict. This study focused on exploring the hypothesized human-elephant conflict on the Selela corridor, specifically in Selela village, as well as GPS (Global Positioning System) mapping evidence of elephant travel along the projected Selela elephant corridor connecting Ngorongoro Conservation Area (NCA), to Selela Forest Reserve (SFR), and finally to …


Influence Of A Suite Of Environmentally Relevant Conditions On Pbt Leaching From, And Sorption To, Marine Microplastic Debris, Robert C. Hale, Da Chen Dec 2016

Influence Of A Suite Of Environmentally Relevant Conditions On Pbt Leaching From, And Sorption To, Marine Microplastic Debris, Robert C. Hale, Da Chen

Reports

Synthetic polymers (plastics) enter marine environments from terrestrial and marine-based sources. The manner of release, the plastic’s composition/properties and ambient marine conditions determine debris fate and its impacts on living resources. It was long assumed that all plastics were persistent and inert, possessing negligible potential for chemical impacts. However, in reality, commercial polymers exhibit a range of potentials for interactions. Persistent, bioaccumulative and toxic (PBT) chemicals are lipophilic and may concentrate from ambient waters by orders of magnitude on polymer surfaces (Teuten et al., 2007). The type of polymer affects the degree of PBT sorption. Indeed, plastics have been found …


Watershed Modeling And Sediment Yield Prediction Of The Los Olmos Creek Watershed In South Texas, Rockford Miller, Jungseok Ho, Chu-Lin Cheng Dec 2016

Watershed Modeling And Sediment Yield Prediction Of The Los Olmos Creek Watershed In South Texas, Rockford Miller, Jungseok Ho, Chu-Lin Cheng

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Studying the sediment that accumulates in a stream is an important aspect in the study of water quality and resources. With respect to water quality, the main issue is the turbidity of the water. Increased losses of natural landscape increase the erosion process in turn raising the turbidity of the water and reducing the light that can penetrate to the water reducing the growth of aquatic life. With respect to water resources, sediment accumulates in the river ways, harbors, and in dams reducing the effectiveness of these resources. This study focused on determining the amount of sediment that is outputted …


Phthalate Plasticizers Covalently Linked To Pvc Via Copper-Free Or Copper Catalyzed Axide-Alkyne Cycloadditions, Aruna Earla, Li Longbo, Philip Costanzo, Rebecca Braslau Dec 2016

Phthalate Plasticizers Covalently Linked To Pvc Via Copper-Free Or Copper Catalyzed Axide-Alkyne Cycloadditions, Aruna Earla, Li Longbo, Philip Costanzo, Rebecca Braslau

Chemistry and Biochemistry

Plasticization of PVC was carried out by covalently linking phthalate derivatives via copper-free (thermal) or copper catalyzed azide-alkyne cycloadditions. Di(2-ethylhexyl) phthalate derivatives (DEHP-ether and DEHP-ester) were synthesized and appended to PVC at two different densities. The glass transition temperatures of the modified PVC decreased with increasing content of plasticizer. PVC-DEHP-ether gave lower glass transition temperatures than PVC-DEHP-ester, reflecting the enhanced flexibility of the ether versus ester linker.


Using Gis To Predict Cetacean Strandings Related To Harmful Algal Blooms, Jessica L. Boyd Dec 2016

Using Gis To Predict Cetacean Strandings Related To Harmful Algal Blooms, Jessica L. Boyd

HCNSO Student Capstones

Exposure to harmful algal bloom (HAB) toxins, such as Karenia brevis, has been linked to cetacean strandings and mortalities. Biological and environmental data from a bottlenose dolphin (Tursiops truncatus) Unusual Mortality Event (UME) in 2004 are compared to those from pilot whale (Globicephala macrorhynchus) mass stranding events in 2013-2014 in western Florida. Geographical Information Systems (GIS) maps have been created by overlaying stranding locations and select K. brevis presence data in order to identify common spatial and temporal trends. Preliminary results indicate that elevated K. brevis levels (>10,000 cells/L) in Sarasota Bay during January-February and November may …


A Review Of Present And Alternative Lionfish Controls In The Western Atlantic, Adam Rittermann Dec 2016

A Review Of Present And Alternative Lionfish Controls In The Western Atlantic, Adam Rittermann

HCNSO Student Capstones

Lionfish (Pterois volitans and Pterois miles) are the first recorded invasive piscivore in the Caribbean and have become a threat to native species. As generalist consumers, lionfish have a broad diet and reduce prey and competitor abundance and juvenile recruitment. To confront this problem, this paper serves to review all of the current and alternative future controls available to manage lionfish populations in the Western Atlantic and determine where focus is lacking. Derby and cull efforts are the only management efforts in place and are not effective in their current state as these local events have short-term benefits, …


An Evaluation Of The Seagrass Habitat In North Biscayne Bay, Florida, In Relation To A Changing Environment And Urbanization In The Port Of Miami Harbor Basin 2005-2011, Sara M. Jarossy Dec 2016

An Evaluation Of The Seagrass Habitat In North Biscayne Bay, Florida, In Relation To A Changing Environment And Urbanization In The Port Of Miami Harbor Basin 2005-2011, Sara M. Jarossy

HCNSO Student Theses and Dissertations

Seagrass habitats in South Florida are exceptionally valuable. They play an important ecological role in the coastal environment by stabilizing sediment, providing habitat for other species and supporting a whole food web. The availability of light and nutrients in aquatic ecosystems are the driving factors behind seagrass distribution. Water quality has been known to influence the abundance, distribution and composition of seagrass beds. South Florida has extensive diverse coastal communities. Throughout its human development dramatic changes have occurred in its natural ecosystems. In South Florida, many examples of seagrass habitat loss are documented, with a variety of contributing factors. The …


Grnsight: A Web Application And Service For Visualizing Models Of Small- To Medium-Scale Gene Regulatory Networks, Kam D. Dahlquist, John David N. Dionisio, Ben G. Fitzpatrick, Nicole A. Anguiano, Anindita Varshneya, Britain J. Southwick, Mihir Samdarshi Dec 2016

Grnsight: A Web Application And Service For Visualizing Models Of Small- To Medium-Scale Gene Regulatory Networks, Kam D. Dahlquist, John David N. Dionisio, Ben G. Fitzpatrick, Nicole A. Anguiano, Anindita Varshneya, Britain J. Southwick, Mihir Samdarshi

John David N. Dionisio

GRNsight is a web application and service for visualizing models of gene regulatory networks (GRNs). A gene regulatory network (GRN) consists of genes, transcription factors, and the regulatory connections between them which govern the level of expression of mRNA and protein from genes. The original motivation came from our efforts to perform parameter estimation and forward simulation of the dynamics of a differential equations model of a small GRN with 21 nodes and 31 edges. We wanted a quick and easy way to visualize the weight parameters from the model which represent the direction and magnitude of the influence of …