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Full-Text Articles in Physical Sciences and Mathematics

Ipm Information Technology, John K. Vandyk Jun 2017

Ipm Information Technology, John K. Vandyk

John K. VanDyk

The use of information technology to obtain and manage IPM information will continue to grow. By applying the basic principles of information taxonomies such as tagging information with terms from vocabularies, filtering and aggregation, knowledge workers will have the necessary tools to become increasingly informed about the realm ofiPM.


Winter Grazing Management, Stephen K. Barnhart, James R. Russell, Douglas L. Karlen, Michael J. Tidman Jun 2017

Winter Grazing Management, Stephen K. Barnhart, James R. Russell, Douglas L. Karlen, Michael J. Tidman

Douglas L Karlen

Why winter grazing? Beef cow herd and sheep flock records show that winter feeding costs are livestock producers' single largest production expense. Managing through winter weather while keeping feeding costs low is an essential part of maintaining a profitable operation. Iowa's climate generally allows forage growth only during a 7-to-8 month period. Extending the grazing of this forage--even an extra 3 or 4 weeks in late autumn and winter--is an economical way to maintain or increase livestock profitability. Some producers extend the grazing season by using stockpiled forage, whereas others use crop residue, and many combine the use of stockpiled …


Vitamin D Status And Demographic And Lifestyle Determinants Among Adults In The United States (Nhanes 2001-2006), Yan Cao, Katie L. Callahan, Sreenivas P. Veeranki, Yang Chen, Ying Liu, Shimin Zheng May 2017

Vitamin D Status And Demographic And Lifestyle Determinants Among Adults In The United States (Nhanes 2001-2006), Yan Cao, Katie L. Callahan, Sreenivas P. Veeranki, Yang Chen, Ying Liu, Shimin Zheng

Shimin Zheng

This study looked at risk factors associated with vitamin D levels in the body among a representative sample of adults in the U.S., NHANES III (2001-2006) data were used to assess the relationship between several demographic and health risk factors and vitamin D levels in the body. The Baseline-Category Logit Model was used to test the association between vitamin D level and the potential risk factors age, education, ethnicity, poverty status, physical activity, smoking, alcohol, obesity, diabetes and total cholesterol with both genders. Vitamin D insufficiency and deficiency were significantly associated with age, race, education, physical activity, obesity, diabetes and …


Associations Of Smoking Status And Serious Psychological Distress With Chronic Obstructive Pulmonary Disease, Ke-Sheng Wang, Liang Wang, Shimin Zheng, Long-Yang Wu May 2017

Associations Of Smoking Status And Serious Psychological Distress With Chronic Obstructive Pulmonary Disease, Ke-Sheng Wang, Liang Wang, Shimin Zheng, Long-Yang Wu

Shimin Zheng

Background: Chronic obstructive pulmonary disease (COPD) has been a major public health problem due to its high prevalence, morbidity, and mortality. Smoking is a major risk factor for COPD, while serious psychological distress (SPD) is prevalent among COPD patients. However, no study focusing on the effect of SPD on COPD has been so far conducted, while few studies have focused on the associations of SPD and behavioral factors with COPD by smoking status. Objectives: This study aimed to examine the associations of SPD and behavioral factors (such as smoking and physical activity) with COPD. Materials and Methods: Weighted logistic regression …


Beyond 3 Au From The Sun: The Hypervolatiles Ch4, C2h6, And Co In The Distant Comet C/2006 W3 (Christensen), Boncho P. Bonev, Geronimo L. Villanueva, Michael A. Disanti, Hermann Boehnhardt, Manuela Lippi, Erika L. Gibb, Lucas Paganini, Michael J. Mumma May 2017

Beyond 3 Au From The Sun: The Hypervolatiles Ch4, C2h6, And Co In The Distant Comet C/2006 W3 (Christensen), Boncho P. Bonev, Geronimo L. Villanueva, Michael A. Disanti, Hermann Boehnhardt, Manuela Lippi, Erika L. Gibb, Lucas Paganini, Michael J. Mumma

Erika Gibb

Comet C/2006 W3 (Christensen) remained outside a heliocentric distance (R h) of 3.1 au throughout its apparition, but it presented an exceptional opportunity to directly sense a suite of molecules released from its nucleus. The Cryogenic Infrared Echelle Spectrograph at ESO-VLT detected infrared emissions from the three "hypervolatiles" (CO, CH4, and C2H6) that have the lowest sublimation temperatures among species that are commonly studied in comets by remote sensing. Even at R h = 3.25 au, the production rate of each molecule exceeded those measured for the same species in a number of other comets, although these comets were observed …


Assessing Public Health Burden Associated With Exposure To Ambient Black Carbon In The United States, Ying Li, Daven K. Henze, Darby Jack, Barron H. Henderson, Patrick L. Kinney Apr 2017

Assessing Public Health Burden Associated With Exposure To Ambient Black Carbon In The United States, Ying Li, Daven K. Henze, Darby Jack, Barron H. Henderson, Patrick L. Kinney

Ying Li

Black carbon (BC) is a significant component of fine particulate matter (PM2.5) air pollution, which has been linked to a series of adverse health effects, in particular premature mortality. Recent scientific research indicates that BC also plays an important role in climate change. Therefore, controlling black carbon emissions provides an opportunity for a double dividend. This study quantifies the national burden of mortality and morbidity attributable to exposure to ambient BC in the United States (US). We use GEOS–Chem, a global 3-D model of atmospheric composition to estimate the 2010 annual average BC levels at 0.5 x 0.667° resolution, and …


Winter Rye Cover Crop Biomass Production, Degradation, And N Recycling, J. L. Pantoja, J. E. Sawyer, D. W. Barker Apr 2017

Winter Rye Cover Crop Biomass Production, Degradation, And N Recycling, J. L. Pantoja, J. E. Sawyer, D. W. Barker

John E. Sawyer

Winter rye (Secale cereale L.) as a cover crop can take up residual inorganic N between annual row crops and therefore be used to help reduce NO3 -–N loss from fields and movement to water systems. However, does the rye N uptake affect N recycling to soil and add to plant available N? The rye carbon:nitrogen (C:N) ratio could also influence N recycling. The objectives of this study were to evaluate rye biomass degradation and N recycling after spring rye termination in a no-till corn (Zea mays L.) - soybean [Glycine max. (L.) Merr.] rotation. A two year experiment (2010-2011) …


Corn And Soybean Response To Sulfur Application On Iowa Soils, J. E. Sawyer, D. W. Barker Apr 2017

Corn And Soybean Response To Sulfur Application On Iowa Soils, J. E. Sawyer, D. W. Barker

John E. Sawyer

Historically sulfur (S) application has not been recommended on Iowa soils for com and soybean production. Prior research has not determined a consistent need for S fertilization in Iowa, with field research indicating no com or soybean yield response to applied S at virtually every site studied (Thorup and Leitch 1975; Webb, 1978; Alesii 1982; Killorn, 1984; Sexton et al., 1998; Mallarino et al., 2000). The soil supply, in combination with sources such as manure and atmospheric deposition has apparently met com and soybean S needs. Sulfur deficiencies have been reported over the years in various areas of the Midwestern …


7Β-Hydroxy­Artemisinin, Paulo B. Carvalho, Bo Liu, Yunshan Wu, John S. Williamson, Mitchell A. Avery Apr 2017

7Β-Hydroxy­Artemisinin, Paulo B. Carvalho, Bo Liu, Yunshan Wu, John S. Williamson, Mitchell A. Avery

John S. Williamson

Crystals of the title compound [systematic name: (3R,6R,7S,8aR,9R,12aR)-7-hydr­oxy-3,6,9-trimethyl­octa­hydro-3,12-ep­oxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one], C15H22O6, were obtained from microbial transformation of artemisinin by a culture of Cunninghamella elegans. The stereochemistry of the compound is consistent with the spectroscopic findings in previously published works. A weak O—H⋯O hydrogen bond occurs in the crystal structure, together with intermolecular C—H⋯O hydrogen bonds.


Discovery Of Thienoquinolone Derivatives As Selective And Atp Non-Competitive Cdk5/P25 Inhibitors By Structure-Based Virtual Screening, Arindam Chatterjee, Stephen J. Cutler, Robert J. Doerksen, Ikhlas A. Khan, John S. Williamson Mar 2017

Discovery Of Thienoquinolone Derivatives As Selective And Atp Non-Competitive Cdk5/P25 Inhibitors By Structure-Based Virtual Screening, Arindam Chatterjee, Stephen J. Cutler, Robert J. Doerksen, Ikhlas A. Khan, John S. Williamson

John S. Williamson

Calpain mediated cleavage of CDK5 natural precursor p35 causes a stable complex formation of CDK5/p25, which leads to hyperphosphorylation of tau. Thus inhibition of this complex is a viable target for numerous acute and chronic neurodegenerative diseases involving tau protein, including Alzheimer’s disease. Since CDK5 has the highest sequence homology with its mitotic counterpart CDK2, our primary goal was to design selective CDK5/p25 inhibitors targeting neurodegeneration. A novel structure-based virtual screening protocol comprised of e-pharmacophore models and virtual screening workflow was used to identify nine compounds from a commercial database containing 2.84 million compounds. An ATP non-competitive and selective thieno[3,2- …


Adrift In A Sea Of Information About Sustainable Seafood: The Maine Consumer Perspective, Catherine V. Schmitt Mar 2017

Adrift In A Sea Of Information About Sustainable Seafood: The Maine Consumer Perspective, Catherine V. Schmitt

Catherine Schmitt

The desire for a sustainable seafood industry that protects the environment and the future of fishing is certainly of interest to consumers, but even here there are conflicting standards, as Catherine Schmitt explores in this article.


The Composition Of Comet C/2012 K1 (Panstarrs) And The Distribution Of Primary Volatile Abundances Among Comets, Nathan X. Roth, Erika L. Gibb, Boncho P. Bonev, Michael A. Disanti, Michael J. Mumma, Geronimo L. Villanueva, Lucas Paganini Mar 2017

The Composition Of Comet C/2012 K1 (Panstarrs) And The Distribution Of Primary Volatile Abundances Among Comets, Nathan X. Roth, Erika L. Gibb, Boncho P. Bonev, Michael A. Disanti, Michael J. Mumma, Geronimo L. Villanueva, Lucas Paganini

Erika Gibb

On 2014 May 22 and 24 we characterized the volatile composition of the dynamically new Oort cloud comet C/2012 K1 (PanSTARRS) using the long-slit, high resolution (λ/Δλ ≈ 25,000) near-infrared echelle spectrograph (NIRSPEC) at the 10 m Keck II telescope on Maunakea, Hawaii. We detected fluorescent emission from six primary volatiles (H2O, HCN, CH4, C2H6, CH3OH, and CO). Upper limits were derived for C2H2, NH3, and H2CO. We report rotational temperatures, production rates, and mixing ratios (relative to water). Compared with median abundance ratios for primary volatiles in other sampled Oort cloud comets, trace gas abundance ratios in C/2012 K1 …


Wait Until Soil Temps Drop Before Applying Anhydrous Ammonia, John E. Sawyer, Barbara Stewart, William Ehm Mar 2017

Wait Until Soil Temps Drop Before Applying Anhydrous Ammonia, John E. Sawyer, Barbara Stewart, William Ehm

John E. Sawyer

With the early harvest, Iowa’s conservation leaders are encouraging farmers to wait until soil temperatures lower before applying anhydrous ammonia (NH3) this fall. Anhydrous ammonia applied before daily soil temperatures remain below 50 degrees Fahrenheit and continue trending lower can result in the nitrogen loss that can impact crop development and have negative environmental impacts, such as enhanced leaching into groundwater and streams once converted to nitrate.


Wet Conditions And Change In Soil Profile Nitrate, John E. Sawyer Mar 2017

Wet Conditions And Change In Soil Profile Nitrate, John E. Sawyer

John E. Sawyer

I wrote an ICM News article February 21, 2013, that provided a summary of fall soil profile nitrate sampling results following the 2012 corn harvest. As I cautioned in that and other articles, the amount of nitrate-N that might remain for a 2013 corn crop depends on springtime rainfall. Unfortunately, much of Iowa has received considerable precipitation since soils thawed, especially the eastern two-thirds of Iowa. The two maps of the Midwest region show the total precipitation and deviation from normal since March 7, 2013. Tile lines are flowing again, and nitrate in the profile will move with percolating water. …


Sulfur Emerges As A Nutritional Issue In Iowa Alfalfa Production, John E. Sawyer, Brian J. Lang, Daniel W. Barker Mar 2017

Sulfur Emerges As A Nutritional Issue In Iowa Alfalfa Production, John E. Sawyer, Brian J. Lang, Daniel W. Barker

John E. Sawyer

Sulfur is often classified as a “secondary” essential element, mainly due to a smaller plant requirement, but also because it is less frequently applied as a fertilizer compared to N, P, and K. This has certainly been the case in Iowa, where research had not documented S deficiency or fertilization need for optimal crop production. However, if deficient, S can have a dramatic effect on plant growth and crop productivity – more than the classification “secondary” would imply.


Novel Cell Penetrating Peptide-Adaptors Effect Intracellular Delivery And Endosomal Escape Of Protein Cargos, John C. Salerno, Verra M. Ngwa, Scott J. Nowak, Carol A. Chrestensen, Allison N. Healey, Jonathan L. Mcmurry Mar 2017

Novel Cell Penetrating Peptide-Adaptors Effect Intracellular Delivery And Endosomal Escape Of Protein Cargos, John C. Salerno, Verra M. Ngwa, Scott J. Nowak, Carol A. Chrestensen, Allison N. Healey, Jonathan L. Mcmurry

Jonathan McMurry

The use of cell penetrating peptides (CPPs) as biomolecular delivery vehicles holds great promise for therapeutic and other applications, but development has been stymied by poor delivery and lack of endosomal escape. We have developed a CPP-adaptor system capable of efficient intracellular delivery and endosomal escape of user-defined protein cargos. The cell penetrating sequence of HIV transactivator of transcription was fused to calmodulin, which binds with subnanomolar affinity to proteins containing a calmodulin binding site. Our strategy has tremendous advantage over prior CPP technologies because it utilizes high affinity noncovalent, but reversible coupling between CPP and cargo. Three different cargo …


A Sonic Net Excludes Birds From An Airfield: Implications For Reducing Bird Strike And Crop Losses, John P. Swaddle, Dana L. Moseley, Mark H. Hinders, Elizabeth P. Smith Feb 2017

A Sonic Net Excludes Birds From An Airfield: Implications For Reducing Bird Strike And Crop Losses, John P. Swaddle, Dana L. Moseley, Mark H. Hinders, Elizabeth P. Smith

John Swaddle

Collisions between birds and aircraft cause billions of dollars of damages annually to civil, commercial, and military aviation. Yet technology to reduce bird strike is not generally effective, especially over longer time periods. Previous information from our lab indicated that filling an area with acoustic noise, which masks important communication channels for birds, can displace European Starlings (Sturnus vulgaris) from food sources. Here we deployed a spatially controlled noise (termed a “sonic net”), designed to overlap with the frequency range of bird vocalizations, at an airfield. By conducting point counts, we monitored the presence of birds for four weeks before …


Work Integrated Learning In Stem In Australian Universities: Final Report: Submitted To The Office Of The Chief Scientist, Daniel Edwards, Kate Perkins, Jacob Pearce, Jennifer Hong Feb 2017

Work Integrated Learning In Stem In Australian Universities: Final Report: Submitted To The Office Of The Chief Scientist, Daniel Edwards, Kate Perkins, Jacob Pearce, Jennifer Hong

Kate Perkins

The Australian Council for Educational Research (ACER) undertook this study for the Office of the Chief Scientist (OCS). It explores the practice and application of Work Integrated Learning (WIL) in STEM, with a particular focus on natural and physical sciences, information technology, and agriculture departments in Australian universities. The project involved a detailed ‘stocktake’ of WIL in practice in these disciplines, with collection of information by interview, survey instruments, consultation with stakeholders and literature reviews. Every university in Australia was visited as part of this project, with interviews and consultation sessions gathering insight from more than 120 academics and support …


Extracting Biochemical Parameters From Protein Distributions Of Vascular Cells, Partha Srinivasan Jan 2017

Extracting Biochemical Parameters From Protein Distributions Of Vascular Cells, Partha Srinivasan

Partha Srinivasan

No abstract provided.


Assessing The Potential To Decrease The Gulf Of Mexico Hypoxic Zone With Midwest Us Perennial Cellulosic Feedstock Production, Andy Vanloocke, Tracy E. Twine, Christopher J. Kucharik, Carl J. Bernacchi Jan 2017

Assessing The Potential To Decrease The Gulf Of Mexico Hypoxic Zone With Midwest Us Perennial Cellulosic Feedstock Production, Andy Vanloocke, Tracy E. Twine, Christopher J. Kucharik, Carl J. Bernacchi

Andy VanLoocke

The goal of this research was to determine the changes in streamflow, dissolved inorganic nitrogen (DIN) leaching and export to the Gulf of Mexico associated with a range of large-scale dedicated perennial cellulosic bioenergy production scenarios within in the Mississippi–Atchafalaya River Basin (MARB). To achieve this goal, we used Agro-IBIS, a vegetation model capable of simulating the biogeochemistry of row crops, miscanthus and switchgrass, coupled with THMB, a hydrology model capable of simulating streamflow and DIN export. Simulations were conducted at varying fertilizer application rates (0–200 kg N ha -1) and fractional replacement (5–25%) of current row crops with miscanthus …


Expression Of Cyanobacterial Fbp/Sbpase In Soybean Prevents Yield Depression Under Future Climate Conditions, Iris H. Kohler, Ursula M. Ruiz-Vera, Andy Vanloocke, Michell L. Thomey, Tom Clemente, Stephen P. Long, Donald R. Ort, Carl J. Bernacchi Jan 2017

Expression Of Cyanobacterial Fbp/Sbpase In Soybean Prevents Yield Depression Under Future Climate Conditions, Iris H. Kohler, Ursula M. Ruiz-Vera, Andy Vanloocke, Michell L. Thomey, Tom Clemente, Stephen P. Long, Donald R. Ort, Carl J. Bernacchi

Andy VanLoocke

Predictions suggest that current crop production needs to double by 2050 to meet global food and energy demands. Based on theory and experimental studies, overexpression of the photosynthetic enzyme sedoheptulose-1,7-bisphosphatase (SBPase) is expected to enhance C3 crop photosynthesis and yields. Here we test how expression of the cyanobacterial, bifunctional fructose-1,6/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) affects carbon assimilation and seed yield (SY) in a major crop (soybean, Glycine max). For three growing seasons, wild-type (WT) and FBP/SBPase-expressing (FS) plants were grown in the field under ambient (400 μmol mol−1) and elevated (600 μmol mol−1) CO2 concentrations [CO2] and under ambient and elevated temperatures (+2.7 …


A Realistic Meteorological Assessment Of Perennial Biofuel Crop Deployment: A Southern Great Plains Perspective, Melissa Wagner, Meng Wang, Gonzalo Miguez-Macho, Jesse Miller, Andy Vanloocke, Justin E. Bagley, Carl J. Bernacchi, Matei Georgescu Jan 2017

A Realistic Meteorological Assessment Of Perennial Biofuel Crop Deployment: A Southern Great Plains Perspective, Melissa Wagner, Meng Wang, Gonzalo Miguez-Macho, Jesse Miller, Andy Vanloocke, Justin E. Bagley, Carl J. Bernacchi, Matei Georgescu

Andy VanLoocke

Utility of perennial bioenergy crops (e.g., switchgrass and miscanthus) offers unique opportunities to transition toward a more sustainable energy pathway due to their reduced carbon footprint, averted competition with food crops, and ability to grow on abandoned and degraded farmlands. Studies that have examined biogeophysical impacts of these crops noted a positive feedback between near-surface cooling and enhanced evapotranspiration (ET), but also potential unintended consequences of soil moisture and groundwater depletion. To better understand hydrometeorological effects of perennial bioenergy crop expansion, this study conducted high-resolution (2-km grid spacing) simulations with a state-of-the-art atmospheric model (Weather Research and Forecasting system) dynamically …


Impacts Of Second-Generation Biofuel Feedstock Production In The Central U.S. On The Hydrologic Cycle And Global Warming Mitigation Potential, K. J. Harding, T. E. Twine, Andy Vanloocke, J. E. Bagley, J. Hill Jan 2017

Impacts Of Second-Generation Biofuel Feedstock Production In The Central U.S. On The Hydrologic Cycle And Global Warming Mitigation Potential, K. J. Harding, T. E. Twine, Andy Vanloocke, J. E. Bagley, J. Hill

Andy VanLoocke

Biofuel feedstocks provide a renewable energy source that can reduce fossil fuel emissions; however, if produced on a large scale they can also impact local to regional water and carbon budgets. Simulation results for 2005–2014 from a regional weather model adapted to simulate the growth of two perennial grass biofuel feedstocks suggest that replacing at least half the current annual cropland with these grasses would increase water use efficiency and drive greater rainfall downwind of perturbed grid cells, but increased evapotranspiration (ET) might switch the Mississippi River basin from having a net warm-season surplus of water (precipitation minus ET) to …


Candidate Perennial Bioenergy Grasses Have A Higher Albedo Than Annual Row Crops, Jesse N. Miller, Andy Vanloocke, Nuria Gomez-Casanovas, Carl J. Bernacchi Jan 2017

Candidate Perennial Bioenergy Grasses Have A Higher Albedo Than Annual Row Crops, Jesse N. Miller, Andy Vanloocke, Nuria Gomez-Casanovas, Carl J. Bernacchi

Andy VanLoocke

The production of perennial cellulosic feedstocks for bioenergy presents the potential to diversify regional economies and the national energy supply, while also serving as climate ‘regulators’ due to a number of biogeochemical and biogeophysical differences relative to row crops. Numerous observational and model-based approaches have investigated biogeochemical trade-offs, such as increased carbon sequestration and increased water use, associated with growing cellulosic feedstocks. A less understood aspect is the biogeophysical changes associated with the difference in albedo (a), which could alter the local energy balance and cause local to regional cooling several times larger than that associated with offsetting carbon. Here, …


The Costs Of Photorespiration To Food Production Now And In The Future, Berkley J. Walker, Andy Vanloocke, Carl J. Bernacchi, Donald R. Ort Jan 2017

The Costs Of Photorespiration To Food Production Now And In The Future, Berkley J. Walker, Andy Vanloocke, Carl J. Bernacchi, Donald R. Ort

Andy VanLoocke

Photorespiration is essential for C3 plants but operates at the massive expense of fixed carbon dioxide and energy. Photorespiration is initiated when the initial enzyme of photosynthesis, ribulose-1,5-bisphosphate carboxylase/ oxygenase (Rubisco), reacts with oxygen instead of carbon dioxide and produces a toxic compound that is then recycled by photorespiration. Photorespiration can be modeled at the canopy and regional scales to determine its cost under current and future atmospheres. A regional-scale model reveals that photorespiration currently decreases US soybean and wheat yields by 36% and 20%, respectively, and a 5% decrease in the losses due to photorespiration would be worth approximately …


Research Needs And Challenges In The Few System: Coupling Economic Models With Agronomic, Hydrologic, And Bioenergy Models For Sustainable Food, Energy, And Water Systems, Catherine L. Kling, Raymond W. Arritt, Gray Calhoun, David A. Keiser, John M. Antle, Jeffery G. Arnold, Miguel Carriquiry, Indrajeet Chaubey, Peter Christensen, Baskar Ganapathysubramanian, Philip Gassman, William Gutowski, Thomas W. Hertel, Gerritt Hoogenboom, Elena Irwin, Madhu Khanna, Pierre Mérel, Daniel J. Phaneuf, Andrew Plantinga, Stephen Polasky, Paul Preckel, Sergey Rabotyagov, Ivan Rudik, Silvia Secchi, Aaron Smith, Andrew Vanloocke, Calvin Wolter, Jinhua Zhao, Wendong Zhang Jan 2017

Research Needs And Challenges In The Few System: Coupling Economic Models With Agronomic, Hydrologic, And Bioenergy Models For Sustainable Food, Energy, And Water Systems, Catherine L. Kling, Raymond W. Arritt, Gray Calhoun, David A. Keiser, John M. Antle, Jeffery G. Arnold, Miguel Carriquiry, Indrajeet Chaubey, Peter Christensen, Baskar Ganapathysubramanian, Philip Gassman, William Gutowski, Thomas W. Hertel, Gerritt Hoogenboom, Elena Irwin, Madhu Khanna, Pierre Mérel, Daniel J. Phaneuf, Andrew Plantinga, Stephen Polasky, Paul Preckel, Sergey Rabotyagov, Ivan Rudik, Silvia Secchi, Aaron Smith, Andrew Vanloocke, Calvin Wolter, Jinhua Zhao, Wendong Zhang

Andy VanLoocke

On October 12–13, a workshop funded by the National Science Foundation was held at Iowa State University in Ames, Iowa with a goal of identifying research needs related to coupled economic and biophysical models within the FEW system. Approximately 80 people attended the workshop with about half representing the social sciences (primarily economics) and the rest from the physical and natural sciences. The focus and attendees were chosen so that findings would be particularly relevant to SBE research needs while taking into account the critical connectivity needed between social sciences and other disciplines. We have identified several major gaps in …


Deep Learning Methods For Protein Torsion Angle Prediction, Haiou Li, Jie Hou, Badri Adhikari, Qiang Lyu, Jianlin Cheng Jan 2017

Deep Learning Methods For Protein Torsion Angle Prediction, Haiou Li, Jie Hou, Badri Adhikari, Qiang Lyu, Jianlin Cheng

Badri Adhikari

No abstract provided.


Cyclipostins And Cyclophostin Analogs As Promising Compounds In The Fight Against Tuberculosis, Phuong Chi Nguyen, Vincent Delorme, Anaïs Bénarouche, Benjamin P. Martin, Rishi Paudel, Giri R. Gnawali, Abdeldjalil Madani, Rémy Puppo, Valérie Landry, Laurent Kremer, Priscille Brodin, Christopher D. Spilling, Jean-François Cavalier, Stéphane Canaan Jan 2017

Cyclipostins And Cyclophostin Analogs As Promising Compounds In The Fight Against Tuberculosis, Phuong Chi Nguyen, Vincent Delorme, Anaïs Bénarouche, Benjamin P. Martin, Rishi Paudel, Giri R. Gnawali, Abdeldjalil Madani, Rémy Puppo, Valérie Landry, Laurent Kremer, Priscille Brodin, Christopher D. Spilling, Jean-François Cavalier, Stéphane Canaan

Christopher Spilling

A new class of Cyclophostin and Cyclipostins (CyC) analogs have been investigated against Mycobacterium tuberculosis H37Rv (M. tb) grown either in broth medium or inside macrophages. Our compounds displayed a diversity of action by acting either on extracellular M. tb bacterial growth only, or both intracellularly on infected macrophages as well as extracellularly on bacterial growth with very low toxicity towards host macrophages. Among the eight potential CyCs identified, CyC 17 exhibited the best extracellular antitubercular activity (MIC50 = 500 nM). This compound was selected and further used in a competitive labelling/enrichment assay against the activity-based probe Desthiobiotin-FP in order …


Evolution Of Floral Zygomorphy In Androecium And Corolla In Solanaceae, Jingbo Zhang, Peter F. Stevens, Wenheng Zhang Jan 2017

Evolution Of Floral Zygomorphy In Androecium And Corolla In Solanaceae, Jingbo Zhang, Peter F. Stevens, Wenheng Zhang

Peter Stevens

In Solanaceae, a group dominated by actinomorphic‐flowered species, floral zygomorphy is frequently observed among the early‐branching clades. Morphological studies indicated that a zygomorphic androecium is much more common than a zygomorphic corolla in the family. Ontogenic studies suggested the evolution of floral zygomorphy in these two whorls is independent. Here, we have examined the evolution of floral symmetry in the androecium and corolla in Solanaceae. The character states of floral symmetry were assembled for androecium and corolla separately, and ancestral state reconstructions were carried out at both the genus and species levels for Solanaceae and its outgroups. Correlation tests were …


Phylogenetic Patterns Of Rarity In A Regional Species Pool Of Tropical Woody Plants, M. Isabel Loza, Iván Jiménez, Peter M. Jørgensen, Gabriel Arellano, Manuel J. Macía, Vania W. Torrez, Robert E. Ricklefs Jan 2017

Phylogenetic Patterns Of Rarity In A Regional Species Pool Of Tropical Woody Plants, M. Isabel Loza, Iván Jiménez, Peter M. Jørgensen, Gabriel Arellano, Manuel J. Macía, Vania W. Torrez, Robert E. Ricklefs

Robert Ricklefs

Aim
Rarity, which is believed to influence extinction risk, can be defined in terms of local abundance, geographical range size and habitat breadth. Phylogenetic patterns in these attributes provide insight into the extent to which rarity and extinction risk are conserved during evolution and the potential for species‐level heritability. We evaluated phylogenetic signal (i.e., related species resembling each other more than species drawn at random) and evolutionary conservatism (similarity among related species exceeding that expected from a Brownian model of evolution) in three axes of rarity (local abundance, geographical range size and habitat breadth) among species in a regional pool …