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Articles 61 - 90 of 134
Full-Text Articles in Physical Sciences and Mathematics
$N$-Acylazole Mediated Stereoselective And Regioselective Synthesis Of $N$-Substituted Azole Acrylonitriles, Osman Aydin, Şule Kökten, Hakan Ünver, İlhami̇ Çeli̇k
$N$-Acylazole Mediated Stereoselective And Regioselective Synthesis Of $N$-Substituted Azole Acrylonitriles, Osman Aydin, Şule Kökten, Hakan Ünver, İlhami̇ Çeli̇k
Turkish Journal of Chemistry
Regio- and stereoselective synthesis of $N$-substituted azole acrylonitriles has been achieved smoothly in $N,N$-dimethylformamide (DMF) in the presence of potassium carbonate (K$_{2}$CO$_{3})$ as a base catalyst. $N$-Substituted azole acrylonitriles were obtained in moderate to good yields (39%-87%) with a one-pot reaction between readily available $N$-acetylazoles and Baylis-Hillman nitriles. The structural determinations were accomplished by NOESY $^{1}$H NMR and X-ray crystallography.
Molecular Dynamics Simulations Of Adsorption Of Long Pyrene-Peg Chains On A Thin Carbon Nanotube, Peli̇n Deni̇z Akkuş, Ayşe Özge Kürkçüoğlu Levi̇tas
Molecular Dynamics Simulations Of Adsorption Of Long Pyrene-Peg Chains On A Thin Carbon Nanotube, Peli̇n Deni̇z Akkuş, Ayşe Özge Kürkçüoğlu Levi̇tas
Turkish Journal of Chemistry
Carbon nanotubes have emerged as highly promising theranostic agents due to their unique structural/physical features, high surface area, and high drug-loading capacity. The high cytotoxicity of carbon nanotubes can be eliminated by noncovalent coating using hydrophilic polymers. We investigated the adsorption of long pyrene functionalized polyethylene glycol (PEG) chains, PEG$_{2000}$ and PEG$_{5000}$, on a single-walled carbon nanotube (SWNT) from a crowded solution. Full-atom molecular dynamics simulations in explicit water were used to mimic the experimental conditions of noncovalent PEGylation with a stoichiometry of one SWNT to ten pyrene-PEG. Although the diffusional behavior of the pyrene molecules still attached to the …
Detection Of Lard Contamination In Five Different Edible Oils By Ft-Ir Spectroscopy Using A Partial Least Squares Calibration Model, Fazeelah Munir, Syed Ghulam Musharraf, Syed Tufail Hussain Sherazi, Muhammad Imran Malik, Muhmmad Iqbal Bhanger
Detection Of Lard Contamination In Five Different Edible Oils By Ft-Ir Spectroscopy Using A Partial Least Squares Calibration Model, Fazeelah Munir, Syed Ghulam Musharraf, Syed Tufail Hussain Sherazi, Muhammad Imran Malik, Muhmmad Iqbal Bhanger
Turkish Journal of Chemistry
Lard is defined as animal fat acquired from the adipose tissue of pigs and is not permitted for human consumption or external use by certain religions such as Islam and Judaism. Due to its low-cost availability for commercial use, it is often mixed with other vegetable oils mistakenly or deliberately and causes loss of consumer trust; hence, its detection in food products is essential. Consumers tend to know the authenticity of commercially available edible oils. However, edible oils are subjected to adulteration risks with lard, which breaches consumer rights. In the present study, we designed a transmission Fourier transform infrared …
Synthesis Of Smz Derivatives And Investigation Of Effects On Germination, Root, And Plant Growth Of \Textit{Arabidopsis Thaliana} L., Tuğba Güngör, Ferah Cömert Önder, Fati̇h Sezer, Aslihan Özbi̇len, Kemal Meli̇h Taşkin, Mehmet Ay
Synthesis Of Smz Derivatives And Investigation Of Effects On Germination, Root, And Plant Growth Of \Textit{Arabidopsis Thaliana} L., Tuğba Güngör, Ferah Cömert Önder, Fati̇h Sezer, Aslihan Özbi̇len, Kemal Meli̇h Taşkin, Mehmet Ay
Turkish Journal of Chemistry
A series of sulfonamide derivatives were synthesized by reactions with various functional groups containing benzenesulfonyl chlorides and aniline derivatives under different substitution reaction conditions. The structures of SMZ derivatives were confirmed with melting point, FT-IR, $^{1}$H NMR, $^{13}$C NMR, and LC-MS/MS techniques. In order to investigate the cytotoxic effects of these derivatives, we used a model plant species. The synthesized compounds (S1-S5) and sulfamethazine (SMZ) as a positive control were applied to Arabidopsis thaliana seeds. Our results indicated that S3 and S4 induced shorter roots and lower wet weight in plants. Plants treated with S2 and S5 showed no growth …
On The Azo Dyes Derived From Benzoic And Cinnamic Acids Used As Photosensitizers In Dye-Sensitized Solar Cells, Luka Matovic, Nikola Tasic, Nemanja Trisovic, Jelena Ladarevic, Vesna Vitnik, Zeljko Vitnik, Branimir Grgur, Dusan Mijin
On The Azo Dyes Derived From Benzoic And Cinnamic Acids Used As Photosensitizers In Dye-Sensitized Solar Cells, Luka Matovic, Nikola Tasic, Nemanja Trisovic, Jelena Ladarevic, Vesna Vitnik, Zeljko Vitnik, Branimir Grgur, Dusan Mijin
Turkish Journal of Chemistry
In order to get a better insight into the relationship between molecular structure and photovoltaic performance, six monoazo dye molecules containing benzoic and cinnamic acid moieties were synthesized and their photovoltaic properties were studied. Three of them have not been previously used in solar cells. Spectroscopic measurements of the investigated compounds coupled with theoretical calculations were performed. Short-circuit current density, open-circuit voltage, and fill-factor were determined. It was found that a larger amount of short-circuit current density will be generated if the HOMO--LUMO energy gap is lower, determined by the stability of the molecule and the electronic effect of the …
Reduced Graphene Oxide Supported Tin Oxide-Boron Oxide Flexible Paper Anodes For Li-Ion Batteries, Hi̇lal Köse, Şeyma Dombaycioğlu, Hatem Akbulut, Ali̇ Osman Aydin
Reduced Graphene Oxide Supported Tin Oxide-Boron Oxide Flexible Paper Anodes For Li-Ion Batteries, Hi̇lal Köse, Şeyma Dombaycioğlu, Hatem Akbulut, Ali̇ Osman Aydin
Turkish Journal of Chemistry
Freestanding tin oxide-boron oxide/reduced graphene oxide (SnO$_{2}$-B$_{2}$O$_{3}$/rGO) nanocomposite anode was produced for Li-ion cells. This binder-free flexible paper anode structure was fabricated by combining SnO$_{2}$-B$_{2}$O$_{3}$ composite and graphene oxide which were synthesized through the sol-gel method and Hummers' method, respectively. Field emission gun scanning electron microscopy, high-resolution transmission electron microscopy, energy dispersive X-ray spectrometer, Fourier transform infrared spectroscopy, Raman spectroscopy, and X-ray diffraction were utilized to characterize anode materials. The Williamson-Hall (W-H) analysis was applied using XRD data to determine crystal size and strain of the lattice. Electrochemical tests, cyclic voltammetry, and electrochemical impedance spectroscopy measurements were performed to determine …
Density Functional Theory-Supported Studies Of Structural And Electronic Properties Of Substituted-Phenol Derivatives Synthesized By Efficient O- Or C-Arylation Via Chan--Lam Or Suzuki Cross-Coupling Reactions, Hafiz Mansoor Ikram, Nasir Rasool, Muhammad Ali Hashmi, Muhammad Arfan Anjum, Kulsoom Ghulam Ali, Muhammad Zubair, Gulraiz Ahmad, Tariq Mahmood
Density Functional Theory-Supported Studies Of Structural And Electronic Properties Of Substituted-Phenol Derivatives Synthesized By Efficient O- Or C-Arylation Via Chan--Lam Or Suzuki Cross-Coupling Reactions, Hafiz Mansoor Ikram, Nasir Rasool, Muhammad Ali Hashmi, Muhammad Arfan Anjum, Kulsoom Ghulam Ali, Muhammad Zubair, Gulraiz Ahmad, Tariq Mahmood
Turkish Journal of Chemistry
The present study reports the efficient synthesis and computational studies of the structural and electronic properties of some interesting substituted phenol derivatives. Efficient and versatile procedures to synthesize a series of diaryl ether derivatives (2a-2c, 4a-4h) and bis-arylated products (5a-5c) are described. In this manuscript, using the commercially available starting material 1 and 3, a 1-step approach was developed by means of Cu(II)-mediated Chan-Lam and Pd-catalyzed Suzuki cross-coupling reactions to synthesize diaryl ether and bis-arylated products with moderate to good yields. The starting substrates, 2-bromo-4-methylphenol 1 or 2,4-dibromophenol 3, were both treated with several arylboronic acids, which led to the …
Mwcnts-Fe$_{2}$O$_{3}$ Nanoparticle Nanohybrid-Based Highly Sensitive Electrochemical Sensor For The Detection Of Kaempferol In Broccoli Samples, Nomnotho Jiyane, Myalowenkosi I. Sabela, Suvardhan Kanchi, Phumlane S. Mdluli, Mavis Xhakaza, Olayide A. Arodola, Krishna Bisetty
Mwcnts-Fe$_{2}$O$_{3}$ Nanoparticle Nanohybrid-Based Highly Sensitive Electrochemical Sensor For The Detection Of Kaempferol In Broccoli Samples, Nomnotho Jiyane, Myalowenkosi I. Sabela, Suvardhan Kanchi, Phumlane S. Mdluli, Mavis Xhakaza, Olayide A. Arodola, Krishna Bisetty
Turkish Journal of Chemistry
This work reports an electrochemical sensor with a modified glassy carbon electrode for the detection of kaempferol. The method was tailored by the immobilization of multiwalled carbon nanotubes (MWCNTs) assimilated with Fe$_{2}$O$_{3}$ nanoparticles (NPs) onto the electrode surface to detect kaempferol using differential pulse voltammetry. Thermogravimetric, transmission electron microscopic, cyclic, and differential voltammetric techniques were employed to characterize the developed electrochemical sensor. The kaempferol produces an anodic quasireversible peak at pH 6.6 in phosphate buffer with Fe$_{2}$O$_{3}$NPs/MWCNTs/GCE. The current of the anodic peak at 0.32 V increases linearly upon addition of kaempferol standard, resulting in Ip($\mu $A) = 1.577($\mu $M) …
Natural Diterpenoid Alysine A Isolated From Teucrium Alyssifolium Exerts Antidiabetic Effect Via Enhanced Glucose Uptake And Suppressed Glucose Absorption, Alaatti̇n Şen, Buket Ayar, Anil Yilmaz, Özden Özgün Acar, Gurbet Çeli̇k Turgut, Gülaçti Topçu
Natural Diterpenoid Alysine A Isolated From Teucrium Alyssifolium Exerts Antidiabetic Effect Via Enhanced Glucose Uptake And Suppressed Glucose Absorption, Alaatti̇n Şen, Buket Ayar, Anil Yilmaz, Özden Özgün Acar, Gurbet Çeli̇k Turgut, Gülaçti Topçu
Turkish Journal of Chemistry
Teucrium species have been used in folk medicine as antidiabetic, antiinflammatory, antiulcer, and antibacterial agents. We have explored in vitro antidiabetic impacts of 2 natural diterpenoids, alysine A and alysine B, isolated from Teucrium alyssifolium. The lactate dehydrogenase (LDH) cytotoxicity assay, glucose uptake test, glucose utilization (glycogen content) test, glucose transport test, glucose absorption ($\alpha $-glucosidase activity) test, insulin secretion test, RNA isolation and cDNA synthesis assay, qPCR quantification assays, and statistical analyses were carried out in the present study. Alysine A exerted the following effects at non-cytotoxic doses: . Enhanced the glucose uptake, as much as the insulin in …
Anticancer And Antiangiogenesis Activities Of Novel Synthesized 2-Substituted Benzimidazoles Molecules, Adem Güner, Eli̇fsu Polatli, Tamer Akkan, Hakan Bektaş, Canan Albay
Anticancer And Antiangiogenesis Activities Of Novel Synthesized 2-Substituted Benzimidazoles Molecules, Adem Güner, Eli̇fsu Polatli, Tamer Akkan, Hakan Bektaş, Canan Albay
Turkish Journal of Chemistry
In this study, novel 2-substituted benzimidazoles molecules having triazole, thiadiazole, and oxadiazole rings were synthesized and were evaluated by anticancer, antioxidant/oxidant status, genotoxicity, and antiangiogenesis assays. Anticancer activity of the compounds was determined by MTT (0.5, 5, and 50 $\mu $g/mL) and lactate dehydrogenase (LDH) release assays against human prostate and breast cancer cells. Oxidative status of cells was elicited by total oxidative stress and total antioxidant capacity methods. Chick chorioallantoic membrane assay was used to evaluate the antiangiogenic activity. Genotoxicity was evaluated by the sister chromatid exchange (SCE) and micronucleus (MN) tests in lymphocyte cultured human blood. Our results …
Silylation Of Epoxidized Soybean Oil With Triethoxysilanes, Synthesis And Characterization Of Their Polyurethanes, Aynur Özşeker, Kemal Karadeni̇z, Mustafa Yasi̇n Şen
Silylation Of Epoxidized Soybean Oil With Triethoxysilanes, Synthesis And Characterization Of Their Polyurethanes, Aynur Özşeker, Kemal Karadeni̇z, Mustafa Yasi̇n Şen
Turkish Journal of Chemistry
Silylation of epoxidized soybean oil (ESBO) was carried out by epoxy ring opening reaction of methoxy and ethoxy silane compounds. $^{1}$H NMR and FTIR spectra confirmed that two novel bio-based polyols, PSiTh and PSiAm, were obtained through the ring opening of epoxy by the mercapto and amino moieties of MPTMS and APTES, respectively. Polyurethanes of these polyols were prepared using 4,4'- methylene-bis(phenyl isocyanate) (MDI) to incorporate silanol groups into polymer network and were labeled as PUSiTh and PUSiAm, respectively. To see the impact of silanol and phosphorous groups on flame retardant properties, the chain extended polyurethanes, PUSiThCE and PUSiAmCE were …
Extraction Of High-Purity Silica From Rice Husk Via Hydrochloric Acid Leaching Treatment, Seitkhan Azat, Zhanar Sartova, Kalampyr Bekseitova, Kydyr Askaruly
Extraction Of High-Purity Silica From Rice Husk Via Hydrochloric Acid Leaching Treatment, Seitkhan Azat, Zhanar Sartova, Kalampyr Bekseitova, Kydyr Askaruly
Turkish Journal of Chemistry
The present paper aimed at the investigation of the effect of preliminary acid treatment on the structure and purity of extracted silica. In this study, the acid leaching of rice husk (RH) in 2 M hydrochloric acid solution before the calcination process at 600 $^{\circ}$C was proposed to achieve completely white silica with high specific surface area and low content of impurities. RH, selected from the Almaty Region, Kyzylorda Region, and Turkestan Region was used as the main silica source. The results confirmed that the highest purity (98.2%-99.7%) amorphous silica with a specific surface area between 120 and 980 m$^{2}$ …
Ann-Assisted Forecasting Of Adsorption Efficiency To Remove Heavy Metals, Magdi Buaisha, Şazi̇ye Balku, Şeni̇z Özalp Yaman
Ann-Assisted Forecasting Of Adsorption Efficiency To Remove Heavy Metals, Magdi Buaisha, Şazi̇ye Balku, Şeni̇z Özalp Yaman
Turkish Journal of Chemistry
In wastewater treatment, scientific and practical models utilizing numerical computational techniques such as artificial neural networks (ANNs) can significantly help to improve the process as a whole through adsorption systems. In the modeling of the adsorption efficiency for heavy metals from wastewater, some kinetic models have been used such as pseudo first-order and second-order. The present work develops an ANN model to forecast the adsorption efficiency of heavy metals such as zinc, nickel, and copper by extracting experimental data from three case studies. To do this, we apply trial-and-error to find the most ideal ANN settings, the efficiency of which …
The Promoted Synthesis Of Minoxidil By Magnetic Nanoparticles Of Cobalt Ferrite (Cofe$_{2}$O$_4$) As A Heterogeneous Reusable Catalyst, Ronak Eisavi, Fateme Ahmadi, Behzad Zeynizadeh, Mehri Kouhkan
The Promoted Synthesis Of Minoxidil By Magnetic Nanoparticles Of Cobalt Ferrite (Cofe$_{2}$O$_4$) As A Heterogeneous Reusable Catalyst, Ronak Eisavi, Fateme Ahmadi, Behzad Zeynizadeh, Mehri Kouhkan
Turkish Journal of Chemistry
Minoxidil (2,4-diamino-6-piperidinopyrimidine 3-oxide) was primarily recognized as a drug for reducing vascular resistance to blood flow. It was later introduced as a more important medicine for topical stimulation of hair growth and baldness reverting as well as treatment of androgenic alopecia through increasing prostaglandin endoperoxide synthesis. In this study, magnetic nanoparticles (MNPs) of spinel ferrites (MFe$_{2}$O$_{4}$, M = Co, Ni, Fe, Cu, and Zn) via solid-state grinding procedure were prepared and then characterized using X-ray diffraction, scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometer, and Fourier transform infrared techniques. The prepared nanoferrites were utilized as efficient and green heterogeneous …
Synthesis And Characterization Of Novel Indanone-Based Spiro-Dihydrobenzofuran Derivatives, Meli̇ha Burcu Gürdere, Neşe Dürü, Yakup Budak, Mustafa Ceylan
Synthesis And Characterization Of Novel Indanone-Based Spiro-Dihydrobenzofuran Derivatives, Meli̇ha Burcu Gürdere, Neşe Dürü, Yakup Budak, Mustafa Ceylan
Turkish Journal of Chemistry
In this study, the synthesis and characterization of novel indanone-based spiro-dihydrobenzofuran derivatives were examined. Firstly, chalcone-like compounds 4a-k, ($E)$-2-benzylidene-2,3-dihydro-1$H$-inden-1-one derivatives, were synthesized by the base-catalyzed addition of benzaldehyde derivatives to 2,3-dihydro-1$H$-inden-1-one. Then Mn(OAc)$_{3}$-mediated addition of dimedone (2) to the chalcone-like compounds gave two novel spiro-dihydrobenzofuran isomers: (3$S)$-6,6-dimethyl-3-aryl-6,7-dihydro-3$H$-spiro [benzofuran-2,2'-indene]-1',4(3'$H$,5$H)$-dione (5a-k) and (2'$S)$-6,6-dimethyl-2-aryl-6,7-dihydro-2$H$-spiro[benzofuran-3,2'-indene]-1',4(3'$H$,5$H)$-dione (6a-k) in good yields. The isomers were separated by column chromatography and their structures were elucidated on the basis of spectral data (NMR, IR) and elemental analysis.
Ionic Liquid-Based Graphene Oxide-Coated Fiber For Headspace-Solid Phase Microextraction Of Polycyclic Aromatic Hydrocarbons In Water Samples, Peli̇n Erdem, Paniz Tashakkori, Melek Merdi̇van, Serap Seyhan Bozkurt
Ionic Liquid-Based Graphene Oxide-Coated Fiber For Headspace-Solid Phase Microextraction Of Polycyclic Aromatic Hydrocarbons In Water Samples, Peli̇n Erdem, Paniz Tashakkori, Melek Merdi̇van, Serap Seyhan Bozkurt
Turkish Journal of Chemistry
Ionic liquid (IL) containing amino and vinyl terminated imidazolium cation and bis[(trifluoromethyl)sulfonyl] imide anion-functionalized graphene oxide (GO) coating material was prepared and coated on a stainless steel wire by a sol-gel technique for headspace-solid phase microextraction (HS-SPME). Its extraction performance was checked by HS-SPME of polycyclic aromatic hydrocarbons (PAHs) coupled to gas chromatography with mass spectrometry (GC-MS). The extraction capability of the IL-functionalized GO-coated fiber was comparable with that of the commercial fibers of polydimethylsiloxane (PDMS) and polydimethylsiloxane/carboxen/divinylbenzene (PDMS/CAR/DVB). Under the optimized conditions, such as extraction temperature, extraction time, and salting-out, the proposed HS-SPME-GC-MS method presented a wide working range …
Modeling And Optimizing Microwave-Assisted Extraction Of Antioxidant Compounds From Marigold Calendula Officinalis L. Using Response Surface Methodology, Burcu Bekdeşer
Turkish Journal of Chemistry
Calendula officinalis L. is a commercially important plant that finds application in the treatment of various diseases in traditional medicine. The total antioxidant capacity, radical scavenging activity, and total phenolic content of marigold extracts were investigated by Folin, CUPRAC, and DPPH assays, respectively. The optimum operating conditions of microwave-assisted extraction (MAE) including temperature, extraction time, solvent-to-solid ratio, and solvent concentration were ascertained by employing response surface methodology (RSM). The solvent (ethanol) concentration was the most significant operating factor among all responses of MAE. At the optimum extraction conditions, the maximum yield of total phenolic content, total antioxidant capacity, and radical …
Glucose Oxidase Immobilized Biofuel Cell Flow Channel Geometry Analysis By Cfd Simulations, Sali̇h Obut, Tahsi̇n Bahar
Glucose Oxidase Immobilized Biofuel Cell Flow Channel Geometry Analysis By Cfd Simulations, Sali̇h Obut, Tahsi̇n Bahar
Turkish Journal of Chemistry
Glucose oxidase was covalently immobilized to a porous electrode, which was developed by using ferrocene functionalized polyethyleneimine, multiwall carbon nanotubes, and carbon cloth for biofuel cell applications in our recent studies. The kinetics parameters (i.e. k$_{M}$, V$_{max})$ and other parameters required for the modeling study were determined experimentally. Fuel cell flow channel geometry was analyzed by a computational fluid dynamics modeling approach. Substrate flow rate and mass transfer for each proposed channel type were considered in the simulations. The results showed that serpentine type flow channels are advantageous over pin type or parallel flow channels to acquire sufficient performance from …
Synthesis And Characterization Of Novel Mussel-Inspired Benzoxazines By Thiol-Benzoxazine Chemistry, Mustafa Arslan
Synthesis And Characterization Of Novel Mussel-Inspired Benzoxazines By Thiol-Benzoxazine Chemistry, Mustafa Arslan
Turkish Journal of Chemistry
A catechol-based benzoxazine copolymer is reported via a new approach using an oxazine-thiol reaction. The main chain benzoxazine precursor was obtained via the classic benzoxazine synthesis methodology using the raw chemicals catechol, formaldehyde, and 4,7,10-trioxa-1,13-tridecanediamine. The countercomponent was synthesized from poly(ethylene glycol) methyl ether via the Fischer esterification reaction. The obtained reactive catechol-based benzoxazine was then reacted in mild conditions with polymeric thiol precursor to obtain a copolymer structure. The precursors and the resulting structure were characterized by thermal and spectral analyses using DSC, TGA, FT-IR,$^{\, 1}$H NMR, and GPC. Film formation was also demonstrated with unreacted oxazine ring units …
Investigation Of The Effects Of Some Water-Soluble Vitamins On Glutathione Reductase Enzyme Purified From Bovine Liver, Mehmet Riza Kivanç, Vedat Türkoğlu
Investigation Of The Effects Of Some Water-Soluble Vitamins On Glutathione Reductase Enzyme Purified From Bovine Liver, Mehmet Riza Kivanç, Vedat Türkoğlu
Turkish Journal of Chemistry
Glutathione reductase (GR, EC 1.8.1.7) is an antioxidant enzyme and is involved in the reducing reaction of oxidized glutathione. Glutathione and reduced glutathione are very crucial for micro- and macroorganisms because of their barrier function against radicals. Therefore, the aim of this article was to purify GR and evaluate the relationship between purified GR and vitamins. GR was purified from bovine liver using 2',5'-ADP Sepharose 4B column materials. To check the purity of each subunit of the enzyme, SDS-PAGE electrophoresis was performed and each one was 55 kDa. Afterwards, specific activity and purified ratio for the enzyme were calculated as …
Synthesis Of Hofmann-Type Zn(H$_2$O)$_2$Ni(Cn)$_4$.Ng (G = Water And 1,4-Dioxane) Clathrates And The Determination Of Their Structural Properties By Various Spectroscopic Methods, Zeki̇ Kartal, Onur Şahi̇n, Abdülkeri̇m Yavuz
Synthesis Of Hofmann-Type Zn(H$_2$O)$_2$Ni(Cn)$_4$.Ng (G = Water And 1,4-Dioxane) Clathrates And The Determination Of Their Structural Properties By Various Spectroscopic Methods, Zeki̇ Kartal, Onur Şahi̇n, Abdülkeri̇m Yavuz
Turkish Journal of Chemistry
Two new 2-dimensional cyanide-bridged coordination polymers [Zn(H$_{2}$O)$_{2}$Ni(CN)$_{4}$ 6(H$_{2}$O) and Zn(H$_{2}$O)$_{2}$ Ni(CN)$_{4}$ 3(C$_{4}$H$_{8}$O$_{2})$], which were similar to Hofmann-type clathrates, were synthesized based on [Ni(CN)$_{4}$]$^{2-}$ and Zn$^{2+}$ as building blocks. These substances were synthesized as compounds in crystalline form. Thes tructures of the crystalline compounds were characterized via their spectral analyses. General information about the structures of the newly obtained Hofmann-type clathrates was obtained from their vibration spectra by considering significant changes in the vibration peaks of the cyanide group, water ligand molecule, and guest molecules (water and 1,4-dioxane). The thermal behavior of the Hofmann-type clathrates was investigated in the range of …
Dispersive Liquid-Liquid Microextraction Of Parabens From Pharmaceuticals And Personal Care Products Prior To Their Determination Using Hplc-Dad, Malek Hassan, Usama Alshana, Nusret Ertaş
Dispersive Liquid-Liquid Microextraction Of Parabens From Pharmaceuticals And Personal Care Products Prior To Their Determination Using Hplc-Dad, Malek Hassan, Usama Alshana, Nusret Ertaş
Turkish Journal of Chemistry
Dispersive liquid--liquid microextraction followed by a back-extraction step was combined with HPLC-DAD for the determination of four parabens (i.e. methyl-, ethyl-, propyl-, and butylparaben). Optimum extraction conditions were found as follows: 225 $\mu $L of chloroform, 0.75 mL of ethanol, 7.5 mL of aqueous solution and within an extraction time of 15 s. Back-extraction into 100 $\mu $L of 50 mM sodium hydroxide solution within 20 s resulted in a reversed-phase HPLC-compatible extract. The analytes were separated at 20 $^{\circ}$C using methanol (A) and water (B), 40:60 (A:B, v/v) as the mobile phase, a flow rate of 1.0 mL min$^{-1}$ …
Synthesis And Catalytic Activity Of Ionic Palladium \Textit{N}-Heterocyclic Carbene Complexes, Sedat Yaşar, Mi̇tat Akkoç, Namik Özdemi̇r, İsmai̇l Özdemi̇r
Synthesis And Catalytic Activity Of Ionic Palladium \Textit{N}-Heterocyclic Carbene Complexes, Sedat Yaşar, Mi̇tat Akkoç, Namik Özdemi̇r, İsmai̇l Özdemi̇r
Turkish Journal of Chemistry
The synthesis of 3 benzimidazole-based ionic Pd(II)-NHC complexes (NHC:$N$-heterocyclic carbene) is presented. The structures of the complexes are as follows: [NHC-PdBr$_{3}$]$^{-}$[NHC]$^{+}$. The ionic palladium(II)-NHC complexes were synthesized in high yields and were fully characterized by nuclear magnetic resonance spectroscopy, X-ray diffraction, LC-MS/MS, and elemental analysis. These complexes have been identified as active catalysts in Suzuki-Miyaura reactions in a solution of 2-propanol and water at room temperature for different aryl bromides.
Evaluation Of The Enrichment And Amplification Effect Of Pentachlorobenzene With Lower Bioconcentration In The Food Chain Before And After Modification, Ruihao Sun, Meijin Du, Yu Li
Evaluation Of The Enrichment And Amplification Effect Of Pentachlorobenzene With Lower Bioconcentration In The Food Chain Before And After Modification, Ruihao Sun, Meijin Du, Yu Li
Turkish Journal of Chemistry
In this paper, in order to construct a 3D quantitative structure--activity relationship (QSAR) model with the chlorobenzene (CB) molecular structure parameter as an independent variable and the octanol-water partition coefficient ($K_{OW})$ as a dependent variable, 9 kinds of CB molecules were used as training sets and 3 kinds of CB molecules were used as test sets. We adopted the QSAR module in the Sybyl-X2.0 software from the Tripos Corporation (USA). The molecular modification of the pentachlorobenzene molecule with low bioconcentration was carried out by combining a three-dimensional contour map and fractional factorial design. The results showed that the toxicity, migration, …
Design, Synthesis, And Antitumor Evaluation Of Novel Methylene Moiety-Tethered Tetrahydroquinoline Derivatives, Esaam Hamied Ahmed Hanashalshahaby, Canan Ünaleroğlu, Ayşe Ak Can, Alp Özgün, Bora Gari̇pcan
Design, Synthesis, And Antitumor Evaluation Of Novel Methylene Moiety-Tethered Tetrahydroquinoline Derivatives, Esaam Hamied Ahmed Hanashalshahaby, Canan Ünaleroğlu, Ayşe Ak Can, Alp Özgün, Bora Gari̇pcan
Turkish Journal of Chemistry
Novel methylene-tethered tetrahydroquinolines (THQs) and cyclopenta[$b$]pyridines were synthesized by one-pot multicomponent reactions of Mannich bases, enolizable ketones, and NH$_{4}$OAc in water by an environmentally friendly K-10 montmorillonite clay-catalyzed reaction. The cytotoxic activities of 1-(2-methyl-8-methylene-5,6,7,8-tetrahydroquinolin-3-yl)ethanone (9a), ethyl 2-methyl-8-methylene-5,6,7,8-tetrahydroquinoline-3 carboxylate (9b), and 1-(2-methyl-7-methylene-6,7-dihydro-5$H$-cyclopenta[$b$]pyridin-3-yl)ethanone (11a) were tested against rat glioblastoma (C6), human breast cancer (MCF-7), prostate cancer (PC3), neuroblastoma (SH-SY5Y), and mouse fibroblast (L929) cell lines in a concentration-dependent (50-300 μM) and time-dependent (24-72 h) manner and expressed as IC$_{50\, }$values. The results showed that compound 9a induced the lowest IC$_{50\, }$values in all cell lines ranging from 111 ± 1.1 μM to …
Synthesis, Characterization, And Investigation Of Singlet Oxygen, Dna Interaction, And Topoisomerase I Inhibition Properties Of Novel Zinc(Ii) Phthalocyanine, Ümi̇t Demi̇rbaş
Turkish Journal of Chemistry
In this work, phthalonitrile (3) and zinc(II) phthalocyanine (4) were prepared. To determine the photodynamic therapy potential of compound 4, singlet oxygen quantum yield, DNA binding and cleavage, and topoisomerase I inhibition experiments were performed. The singlet oxygen quantum yield value of compound 4 was found higher than that of the standard unsubstituted zinc(II) phthalocyanine compound (Std-ZnPc). The binding experiments showed that compound 4 interacted with ct-DNA strongly via nonintercalation mode. pBR322 plasmid DNA cleavage activity of the compound was investigated using agarose gel electrophoresis. The results showed that the compound 4 had important DNA cleavage activity. The E. coli …
Synthesis And Characterization Of Unsaturated Diacyl And Alkyl-Acyl Piperazine Derivatives, Sai̇t Sari, Seda Ünalan, Mehmet Yilmaz
Synthesis And Characterization Of Unsaturated Diacyl And Alkyl-Acyl Piperazine Derivatives, Sai̇t Sari, Seda Ünalan, Mehmet Yilmaz
Turkish Journal of Chemistry
The aim of this study is to obtain new unsaturated piperazine compounds by the reactions of piperazine (1a) and piperazine derivatives (1b-1d) with acylation reactive groups (a-2j). Methacryloyl piperazine (1b) was synthesized from the reaction of methacrylic anhydride with piperazine (1a). Acyl chlorides (2b-2d) were prepared from the reaction of thionyl chloride with carboxylic acids (3a-3c) obtained as a result of the reaction with malonic acid and suitable aldehyde (5-methylfuran-2-carbaldehyde for 3a, cinnamaldehyde for 3b, and thiophene-2-carbaldehyde for 3c), respectively, by literature methods. Acyl chlorides 2ed and 2f }were obtained from the reaction of commercially purchased carboxylic acids 3d and …
Aqueous Two-Phase Extraction Technique Based On Magnetic Ionic Liquid-Nonionic Surfactant For Phenolic Acids In Grape, Apple, Pear, And Banana, Taşkin Mumcu, Serap Seyhan Bozkurt
Aqueous Two-Phase Extraction Technique Based On Magnetic Ionic Liquid-Nonionic Surfactant For Phenolic Acids In Grape, Apple, Pear, And Banana, Taşkin Mumcu, Serap Seyhan Bozkurt
Turkish Journal of Chemistry
An aqueous two-phase extraction system was constituted using magnetic ionic liquid-nonionic surfactant for phenolic acids and the developed method was applied to apple, grape, pear, and banana samples. Ionic liquids based on imidazolium containing butyl, allyl, and benzyl groups were used for extraction. The parameters influencing the extraction efficiency such as volume of ionic liquids, type and amount of surfactant and salt, ultrasound extraction time, temperature, and sample pH were optimized. The extraction efficiencies of ionic liquids were compared for phenolic acids under optimized conditions. Limits of detection and limits of quantification were in the range of 1.34-1.56 μg L$^{-1\, …
Surface Modification Of Polyvinyl Chloride By Polyacrylic Acid Graftas A Polyelectrolyte Membrane Using Ar Plasma, Alaa Fahmy, Mouhamed Abu-Saied, Nasser Morgan, Walid Qutop, Hassan Abdelbary, Tarek Salama
Surface Modification Of Polyvinyl Chloride By Polyacrylic Acid Graftas A Polyelectrolyte Membrane Using Ar Plasma, Alaa Fahmy, Mouhamed Abu-Saied, Nasser Morgan, Walid Qutop, Hassan Abdelbary, Tarek Salama
Turkish Journal of Chemistry
This work reports the synthesis and properties of a new membrane based on polyvinyl chloride (PVC) grafting with polyacrylic acid (PAA) using argon (Ar) plasma. The membranes of PVC were synthesized by solution-casting method, where PAA was deposited as an ultrathin film onto PVC using dielectric barrier discharge at atmospheric pressure with Ar gas. The surface characteristics and chemical composition of the modified membranes were analyzed by water contact angle, scanning electron microscopy, and Fourier transform infrared spectroscopy. Moreover, the electrochemical properties of the membrane were investigated via ion exchange capacity for the purpose of using it as a polyelectrolyte …
The Role Of Diazacrown Ether In The Enhancement Of The Biological Activity Of Silver Nanoparticles, Sarvinaz Hajiyeva, Ulviyya Hasanova, Zarema Gakhramanova, Aygun Israyilova, Khudaverdi Ganbarov, Eldar Gasimov, Fuad Rzayev, Goncha Eyvazova, Alakbar Huseynzada, Gunel Aliyeva, Ilaha Hasanova, Abel Maharramov
The Role Of Diazacrown Ether In The Enhancement Of The Biological Activity Of Silver Nanoparticles, Sarvinaz Hajiyeva, Ulviyya Hasanova, Zarema Gakhramanova, Aygun Israyilova, Khudaverdi Ganbarov, Eldar Gasimov, Fuad Rzayev, Goncha Eyvazova, Alakbar Huseynzada, Gunel Aliyeva, Ilaha Hasanova, Abel Maharramov
Turkish Journal of Chemistry
The nanostructuring of hydroxyl-substituted diazacrown-ether (DC) by silver nanoparticles was obtained by green synthesis method in order to increase the antibacterial activity of silver nanoparticles. The synthesized DC, nanoparticles, and nanosupramolecular complex (Ag@DC) were studied by TEM, powder-XRD, and NMR, IR, and UV spectroscopy methods. The Ag@DC nanostructures were uniform and their sizes ranged from 8 to 18 nm. IR and UV spectra revealed the noncovalent formation of the nanosupramolecular complex. The antibacterial activities of the prepared active agents were investigated on gram-positive and gram-negative bacteria by twofold microdilution method. Ultrastructural study by TEM was performed on \textit{E. coli} BDU12 …