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Extending The Application Of Polyol-Induced Extraction For The Analysis Of Glucocorticoids And Nsaids In Water Using Uhplc-Ms/Ms, Shipra Patel
Seton Hall University Dissertations and Theses (ETDs)
Polyol induced extraction (PIE) is an extraction technique developed and patented by Sowa Jr., Murphy, and Deshpande at Seton Hall University as a method of removal of water from acetonitrile. PIE is a technique that separates water from a mixture containing an organic liquid and water by adding a polyol to the mixture that leads to phase separation of aqueous and organic phase. The goal of this work was to extend the application of PIE and to demonstrate that PIE can be an alternative method for extraction of glucocorticoids and non-steroidal anti-inflammatory drugs (NSAIDS) which then can be analyzed using …