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Seton Hall University Dissertations and Theses (ETDs)
NSAIDs using solid phase microextraction; SPME; comprehensive gas chromatography-time of flight-mass spectrometry; SPME-GCxGC-TOF-MS; water analysis
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Study Of Selectivity In Extraction, Separation, And Detection On Drugs Using Gas Chromatography, Anumeha P. Muthal
Study Of Selectivity In Extraction, Separation, And Detection On Drugs Using Gas Chromatography, Anumeha P. Muthal
Seton Hall University Dissertations and Theses (ETDs)
The selectivity of a method is defined by its ability to determine a particular analyte without interference in a complex mixture. Selectivity in gas chromatography (GC) can be obtained at different points in the analysis including the sample preparation, sample introduction, separation on column and detection. In GC, the first dimension of selectivity can be obtained in sample preparation; the second dimension in chromatographic separation and the third dimension in detection. This research focuses on the relationships between selectivity in these different dimensions, studied using some non-steroidal anti-inflammatory drugs, glucocorticoids, fatty acid methyl esters and polycyclic aromatic hydrocarbons. Recent methodologies …