Physical Sciences and Mathematics Commons^™

Advances In Documentation, Digital Curation, Virtual Exhibition, And A Test Of 3d Geometric Morhpometrics: A Case Study Of The Vanderpool Vessels From The Ancestral Caddo Territory, Robert Z. Selden Jr., Timothy K. Perttula, Michael J. O'Brien

CRHR: Archaeology

Three-dimensional (3D) digital scanning of archaeological materials is typically used as a tool for artifact documentation. With the permission of the Caddo Nation of Oklahoma, 3D documentation of Caddo funerary vessels from the Vanderpool site (41SM77) was conducted with the initial goal of ensuring that these data would be publicly available for future research long after the vessels were repatriated. A digital infrastructure was created to archive and disseminate the resultant 3D datasets, ensuring that they would be accessible by both researchers and the general public (CRHR 2014a). However, 3D imagery can be used for much more than documentation. To …

Planned Missing Data Designs & Small Sample Size: How Small Is Too Small?, Fan Jia, E. Whitney G. Moore, Richard Kinai, Kelly S. Crowe, Alexander M. Schoemann, Todd D. Little

Kinesiology, Health and Sport Studies

Utilizing planned missing data (PMD) designs (ex. 3-form surveys) enables researchers to ask participants fewer questions during the data collection process. An important question, however, is just how few participants are needed to effectively employ planned missing data designs in research studies. This paper explores this question by using simulated three-form planned missing data to assess analytic model convergence, parameter estimate bias, standard error bias, mean squared error (MSE), and relative efficiency (RE).Three models were examined: a one-time point, cross-sectional model with 3 constructs; a two-time point model with 3 constructs at each time point; and a three-time point, mediation …

Bayesian Joint Selection Of Genes And Pathways: Applications In Multiple Myeloma Genomics, Lin Zhang, Jeffrey S. Morris, Jiexin Zhang, Robert Orlowski, Veerabhadran Baladandayuthapani

Jeffrey S. Morris

It is well-established that the development of a disease, especially cancer, is a complex process that results from the joint effects of multiple genes involved in various molecular signaling pathways. In this article, we propose methods to discover genes and molecular pathways significantly associ- ated with clinical outcomes in cancer samples. We exploit the natural hierarchal structure of genes related to a given pathway as a group of interacting genes to conduct selection of both pathways and genes. We posit the problem in a hierarchical structured variable selection (HSVS) framework to analyze the corresponding gene expression data. HSVS methods conduct …

A Comparison Of 12 Algorithms For Matching On The Propensity Score, Peter C. Austin

Peter Austin

Propensity-score matching is increasingly being used to reduce the confounding that can occur in observational studies examining the effects of treatments or interventions on outcomes. We used Monte Carlo simulations to examine the following algorithms for forming matched pairs of treated and untreated subjects: optimal matching, greedy nearest neighbor matching without replacement, and greedy nearest neighbor matching without replacement within specified caliper widths. For each of the latter two algorithms, we examined four different sub-algorithms defined by the order in which treated subjects were selected for matching to an untreated subject: lowest to highest propensity score, highest to lowest propensity …

The Use Of Propensity Score Methods With Survival Or Time-To-Event Outcomes: Reporting Measures Of Effect Similar To Those Used In Randomized Experiments, Peter C. Austin

Peter Austin

Propensity score methods are increasingly being used to estimate causal treatment effects in observational studies. In medical and epidemiological studies, outcomes are frequently time-to-event in nature. Propensity-score methods are often applied incorrectly when estimating the effect of treatment on time-to-event outcomes. This article describes how two different propensity score methods (matching and inverse probability of treatment weighting) can be used to estimate the measures of effect that are frequently reported in randomized controlled trials: (i) marginal survival curves, which describe survival in the population if all subjects were treated or if all subjects were untreated; and (ii) marginal hazard ratios. …

The Performance Of Different Propensity Score Methods For Estimating Absolute Effects Of Treatments On Survival Outcomes: A Simulation Study, Peter C. Austin

Peter Austin

Observational studies are increasingly being used to estimate the effect of treatments, interventions and exposures on outcomes that can occur over time. Historically, the hazard ratio, which is a relative measure of effect, has been reported. However, medical decision making is best informed when both relative and absolute measures of effect are reported. When outcomes are time-to-event in nature, the effect of treatment can also be quantified as the change in mean or median survival time due to treatment and the absolute reduction in the probability of the occurrence of an event within a specified duration of follow-up. We describe …

Pairwise Comparison Of Treatment Levels In Functional Analysis Of Variance With Application To Erythrocyte Hemolysis, Olga A. Vsevolozhskaya, Mark C. Greenwood, Dmitri Holodov

Olga A. Vsevolozhskaya

Motivated by a practical need for the comparison of hemolysis curves at various treatment levels, we propose a novel method for pairwise comparison of mean functional responses. The hemolysis curves—the percent hemolysis as a function of time—of mice erythrocytes (red blood cells) by hydrochloric acid have been measured among different treatment levels. This data set fits well within the functional data analysis paradigm, in which a time series is considered as a realization of the underlying stochastic process or a smooth curve. Previous research has only provided methods for identifying some differences in mean curves at different times. We propose …

Multi-Peak Solutions To Two Types Of Free Boundary Problems, Yi Li, Shuangjie Peng

Mathematics and Statistics Faculty Publications

We consider the existence of multi-peak solutions to two types of free boundary problems arising in confined plasma and steady vortex pair under conditions on the nonlinearity we believe to be almost optimal. Our results show that the “core” of the solution has multiple connected components, whose boundary called free boundary of the problems consists approximately of spheres which shrink to distinct single points as the parameter tends to zero.

Generalized Classes Of Distributions With Applications To Income And Lifetime Data, Shujiao Huang

Electronic Theses and Dissertations

In this thesis, new classes of distributions namely: exponentiated Kumaraswamy-Dagum (EKD), Log-exponentiated Kumaraswamy-Dagum (Log-EKD), McDonald Log-logistic (McLLog) and Gamma-Dagum (GD) distributions are presented. A thorough and comprehensive investigation of these classes of distributions is conducted. Mathematical properties of these classes of distributions including series expansion, hazard and reverse hazard functions, moments, generating functions, mean and median deviations, Bonferroni and Lorenz curves, distribution of order statistics, moments of order statistics and entropies are presented. Estimation of parameters of these distributions via maximum likelihood technique, Fisher information and asymptotic confidence intervals are given. Maximum likelihood estimation of the parameters of the exponentiated …

The Initial Phases Of A Consistent Pricing System That Reflects The Online Sale Value Of A Horse, Curran A. Prettyman

Lewis Honors College Capstone Collection

Horses are one of the most uniquely priced commodities. This document provides a solution to an industry-wide weakness of inconsistent pricing and confusion. In the following report, an evaluation of the industry flaw is presented, an econometric approach is described in full, and a solution is proposed using insight gained from a regression analysis. This report uses an econometric approach to determine the impact of hunter jumper horse qualities on internet sale prices. Data is compiled from bigeq.com for seventy-eight horses in the states of Illinois, Indiana, Kentucky, Michigan, and Ohio. A linear regression analysis for twelve variables establishes that …

Cfd For Evaluation And Treatment Planning Of Aneurysms: Review Of Proposed Clinical Uses And Their Challenges, Bong Jae Chung, Juan Raul Cebral

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

Computational fluid dynamics (CFD) has been used for several years to identify mechanical risk factors associated with aneurysmal evolution and rupture as well as to understand flow characteristics before and after surgical treatments in order to help the clinical decision making process. We used the keywords, “CFD” and “aneurysms” to search recent publications since about 2000, and categorized them into (i) studies of rupture risk factors and (ii) investigations of pre- and post-evaluations of surgical treatment with devices like coils and flow diverters (FD). This search enables us to examine the current status of CFD as a clinical tool and …

Experimental Validation Of Robotic Manifold Tracking In Gyre-Like Flows, Matthew Michini, M. Ani Hsieh, Eric Forgoston, Ira B. Schwartz

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

In this paper, we present a first attempt toward experimental validation of a multi-robot strategy for tracking manifolds and Lagrangian coherent structures (LCS) in flows. LCS exist in natural fluid flows at various scales, and they are time-varying extensions of stable and unstable manifolds of time invariant dynamical systems. In this work, we present the first steps toward experimentally validating our previously proposed real-time manifold and LCS tracking strategy that relies solely on local measurements. Although we have validated the strategy in simulations using analytical flow models, experimental flow data, and actual ocean data, the strategy has never been implemented …

Financial Instability Contagion: A Dynamical Systems Approach, Giuseppe Castellacci, Youngna Choi

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

We build a multi-agent dynamical system for the global economy to investigate and analyse financial crises. The agents are large aggregates of a subeconomy, and the global economy is a collection of subeconomies. We use well-known theories of dynamical systems to represent a financial crisis as propagation of a negative shock on wealth due the breakage of a financial equilibrium. We first extend the framework of the market instability indicator, an early warning signal defined for a single economy as the spectral radius of the Jacobian matrix of the wealth dynamical system. Then, we formulate a quantitative definition of instability …

Oxytetracycline Sorption Onto Iraqi Montmorillonite, M. M. Barbooti, Haiyan Su, Pravin Punamiya, Dibyendu Sarkar

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

This paper assesses the use of certified Iraqi montmorillonite clay as a potential sorbent for the removal of oxytetracycline (OTC) from aqueous solutions. The clay is characterized by a cation exchange capacity of 0.756 meq g-1 and a zero point charge at pH 8.7. Aqueous solutions of OTC were equilibrated with montmorillonite under various experimental conditions, such as OTC concentration, pH and clay content, for 24 h at fixed ionic strength. Two forms of montmorillonite were evaluated: regular and iron-modified form. The effect of pH was minor on OTC adsorption. Kinetic study revealed that the sorption follows a pseudo-second-order model. …

Transportation Of Perishable And Refrigerated Foods In Mylar Foil Bags And Insulated Containers: A Time-Temperature Study, Yanyan Li, John P. Schrade, Haiyan Su, John Specchio

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

Data are lacking on the temperature changes of food during transport without the use of refrigerated trucks. The purpose of this study was to evaluate the ability of several insulated and noninsulated containers with or without frozen gel packs to keep perishable and refrigerated foods within the temperature safe zone in relationship to duration of transport. The study was designed to duplicate the practices exhibited by customers purchasing perishable food products from a cash-and-carry business. Approximately 40 perishable food items were evaluated. Four types of containers were tested: a mylar foil bag, a commercial insulated bag, a generic insulated bag, …

Dynamic Bayesian Approaches To The Statistical Calibration Problem, Derick Lorenzo Rivers

Theses and Dissertations

The problem of statistical calibration of a measuring instrument can be framed both in a statistical context as well as in an engineering context. In the first, the problem is dealt with by distinguishing between the "classical" approach and the "inverse" regression approach. Both of these models are static models and are used to estimate "exact" measurements from measurements that are affected by error. In the engineering context, the variables of interest are considered to be taken at the time at which you observe the measurement. The Bayesian time series analysis method of Dynamic Linear Models (DLM) can be used …

An Investigation Of Sensitivity Of An F Test In Locating Change Points In Linear Regression, Jing Sun

Electronic Theses and Dissertations

Change point is a statistic phenomenon, which has many direct applications in climatology, bioinformatics, finance, oceanography and medical imaging. In this thesis, we investigate the sensitivity of the F-test for detecting change points in linear regression, using a two-phase linear regression model. it offers an effective method to detect "undocumented" change points using a form of an F-test. Using simulated data, we explore its sensitivity and accuracy with respect t different parameters in the model.

Generalized Weibull And Inverse Weibull Distributions With Applications, Valeriia Sherina

Electronic Theses and Dissertations

In this thesis, new classes of Weibull and inverse Weibull distributions including the generalized new modified Weibull (GNMW), gamma-generalized inverse Weibull (GGIW), the weighted proportional inverse Weibull (WPIW) and inverse new modified Weibull (INMW) distributions are introduced. The GNMW contains several sub-models including the new modified Weibull (NMW), generalized modified Weibull (GMW), modified Weibull (MW), Weibull (W) and exponential (E) distributions, just to mention a few. The class of WPIW distributions contains several models such as: length-biased, hazard and reverse hazard proportional inverse Weibull, proportional inverse Weibull, inverse Weibull, inverse exponential, inverse Rayleigh, and Frechet distributions as special cases. Included …

Genetic Association Testing Of Copy Number Variation, Yinglei Li

Theses and Dissertations--Statistics

Copy-number variation (CNV) has been implicated in many complex diseases. It is of great interest to detect and locate such regions through genetic association testings. However, the association testings are complicated by the fact that CNVs usually span multiple markers and thus such markers are correlated to each other. To overcome the difficulty, it is desirable to pool information across the markers. In this thesis, we propose a kernel-based method for aggregation of marker-level tests, in which first we obtain a bunch of p-values through association tests for every marker and then the association test involving CNV is based on …

Performance Modeling And Optimization Techniques For Heterogeneous Computing, Supada Laosooksathit

Doctoral Dissertations

Since Graphics Processing Units (CPUs) have increasingly gained popularity amoung non-graphic and computational applications, known as General-Purpose computation on GPU (GPGPU), CPUs have been deployed in many clusters, including the world's fastest supercomputer. However, to make the most efficiency from a GPU system, one should consider both performance and reliability of the system.

This dissertation makes four major contributions. First, the two-level checkpoint/restart protocol that aims to reduce the checkpoint and recovery costs with a latency hiding strategy in a system between a CPU (Central Processing Unit) and a GPU is proposed. The experimental results and analysis reveals some benefits, …

Fusarium Head Blight Resistance And Agronomic Performance In Soft Red Winter Wheat Populations, Daniela Sarti Dvorjak

Theses and Dissertations--Plant and Soil Sciences

Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe [telomorph: Gibberella zeae Schwein.(Petch)], is recognized as one of the most destructive diseases of wheat (Triticum aestivum L. and T. durum L.) and barley (Hordeum vulgare L.) worldwide. Breeding for FHB resistance must be accompanied by selection for desirable agronomic traits. Donor parents with two FHB resistance quantitative trait loci (QTL) Fhb1 (chromosome 3BS) and QFhs.nau-2DL (chromosome 2DL) were crossed to four adapted SRW wheat lines to generate backcross and forward cross progeny. F₂ individuals were genotyped and assigned to 4 different groups according to presence/ absence of …

A Generalized Family Of Estimators For Estimating Population Mean Using Two Auxiliary Attributes, Sachin Malik, Rajesh Singh, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This paper deals with the problem of estimating the finite population mean when some information on two auxiliary attributes are available. A class of estimators is defined which includes the estimators recently proposed by Malik and Singh (2012), Naik and Gupta (1996) and Singh et al. (2007) as particular cases. It is shown that the proposed estimator is more efficient than the usual mean estimator and other existing estimators. The study is also extended to two-phase sampling. The results have been illustrated numerically by taking empirical population considered in the literature.

A General Procedure Of Estimating Population Mean Using Information On Auxiliary Attribute, Sachin Malik, Rajesh Singh, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This paper deals with the problem of estimating the finite population mean when some information on auxiliary attribute is available. It is shown that the proposed estimator is more efficient than the usual mean estimator and other existing estimators. The results have been illustrated numerically by taking empirical population considered in the literature.

From Amazon To Apple: Modeling Online Retail Sales, Purchase Incidence And Visit Behavior, Anastasios Panagiotelis, Michael S. Smith, Peter Danaher

Michael Stanley Smith

In this study we propose a multivariate stochastic model for website visit duration, page views, purchase incidence and the sale amount for online retailers. The model is constructed by composition from carefully selected distributions, and involves copula components. It allows for the strong nonlinear relationships between the sales and visit variables to be explored in detail, and can be used to construct sales predictions. The model is readily estimated using maximum likelihood, making it an attractive choice in practice given the large sample sizes that are commonplace in online retail studies. We examine a number of top-ranked U.S. online retailers, …

Spectral Density Shrinkage For High-Dimensional Time Series, Mark Fiecas, Rainer Von Sachs

Mark Fiecas

The Cobden-Chevalier Effect: Evaluating The Causal Effect Of The Most Favoured Nation Clause In Presence Of Network Interdependence, Luca De Benedictis, Silvia Nenci

Luca De Benedictis