Veterinary Toxicology and Pharmacology Commons^™

Medication-Induced Esophageal Injury In Cats And Dogs: A Comprehensive Review, Naowarat Suthamnatpong, Aranya Ponpornpisit

The Thai Journal of Veterinary Medicine

Medication-induced esophageal injury (MIEI) is a significant concern in veterinary medicine, affecting the health and well-being of animals undergoing various pharmaceutical treatments. If not addressed promptly, MIEI can lead to severe complications such as esophagitis, esophageal stricture, perforation, and even mortality. This review aims to provide a comprehensive examination of MIEI in veterinary medicine, covering essential aspects such as the basic structure of the esophagus, the epidemiology and etiology of MIEI, and the factors influencing susceptibility. The mechanisms of injury are discussed in detail, focusing on direct mechanical injuries, chemical injuries from medication components, and systemic effects. The review also …

Long-Term Tapering Regimen Use Of Oclacitinib For The Control Of Pruritus In An Atopic Dog, Piyarat Chansiripornchai

The Thai Journal of Veterinary Medicine

Abstract

Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory skin disease with a global distribution, yet it is incurable. A key clinical sign of CAD is pruritus. Oclacitinib has proven effective in managing pruritus in atopic dogs. This case report details the long-term administration of oclacitinib every other day for controlling pruritus in an atopic dog. An 8-year-old atopic Bangkaew dog presented with pruritus, alopecia, and recurrent Malassezia pachydermatis infection. To control the pruritus, the dog received oclacitinib at a dose of 0.4 mg/kg orally every 24 hours for 30 weeks. The pruritus visual analog scale (PVAS) decreased from …