Veterinary Preventive Medicine, Epidemiology, and Public Health Commons^™

First Bovine Vaccine To Prevent Human Schistosomiasis - A Cluster Randomised Phase 3 Clinical Trial, Allen G. Ross, Donald A. Harn, Delia Chy, Marianette Inobaya, Jerric R. Guevarra, Lisa Shollenberger, Yuesheng Li, Donald P. Mcmanus, Darren J. Gray, Gail M. Williams

Biological Sciences Faculty Publications

Objective

Schistosomiasis is a neglected tropical parasitic disease caused by blood flukes of the genus Schistosoma. Schistosoma japonicum is zoonotic in China, the Philippines, and Indonesia, with bovines acting as major reservoirs of human infection. The primary objective of the trial was to examine the impact of a combination of human mass chemotherapy, snail control through mollusciciding, and SjCTPI bovine vaccination on the rate of human infection.

Methods

A 5-year phase IIIa cluster randomized control trial was conducted among 18 schistosomiasis-endemic villages comprising 18,221 residents in Northern Samar, The Philippines.

Results

Overall, bovine vaccination resulted in a statistically significant decrease …

Livestock Cattle As A Predictor Of Schistosomiasis Transmission In Nigeria, Oyetunde T. Oyeyemi, Oluyemi A. Okunlola, Zhiqiang Fu, Yang Hong, Jun-Hu Chen, Lisa M. Shollenberger

Biological Sciences Faculty Publications

Livestock cattle have been widely linked to schistosomiasis epidemiology, but little is known about its contribution to schistosomiasis transmission in Nigeria. The aim of this study is to examine the association between prevalence of schistosomiasis and livestock cattle index in Nigeria. The study's data came from three sources: the demographic and health survey (DHS), the malaria indicators survey (MIS), and the expanded special project for the eradication of neglected tropical diseases (ESPEN). Analysis of variance, correlation, and logistic regression were used to evaluate the mean difference in schistosomiasis prevalence across geopolitical zones, the relationship between schistosomiasis prevalence and livestock cattle, …

Anthelmintic Resistance In Sheep Across Ireland And The Uk: A Literature Review Of The In Vivo Versus In Vitro Methods, Megan Tumulty

SURE Journal: Science Undergraduate Research Experience Journal

Background: The animal welfare and production consequences of gastrointestinal nematode infections, namely Nematodirus battus, on sheep are compelling. The control of gastrointestinal infections has been heavily reliant on the administration of anthelmintics since their introduction into mainstream use in 1960. However, their frequent and often excessive use has resulted in anthelmintic resistance being reported extensively in several gastrointestinal nematode species. The prevalence of anthelmintic resistance as well as the increase in the number of cases of multiple-drug resistance in nematode populations now poses substantial hindrance on the viability of sheep production systems. However, despite the threat N. battus poses …

Species Data And Vector Modeling: Evaluating Datasets For Improved Models Of Ixodes Ricinus Tick Distribution In Europe Under A Changing Climate, Steven Jones

Electronic Theses and Dissertations

To increase capacity for monitoring and surveillance of tick-borne diseases, publicly available tick distribution and climate change datasets are required to create accurate predictive distribution models. It is difficult, however, to assess model accuracy and utility when using incomplete datasets.  The more recent development of comprehensive tick databases for Europe and availability of climate change scenarios from multiple IPCC Assessment Reports allows for improved modeling efforts. Multiple tick datasets were combined and three climate change projections were compared by predicting current and future distributions of Ixodes ricinus ticks in Europe using the MaxEnt species distribution model. Overall, much of Europe …

Prevalence Of Rats And Rodent Borne Pathogens Across Post-Katrina New Orleans, Bruno Marco Ghersi

Doctoral Dissertations

Disasters are happening at an increasingly higher rate and intensity a trend that is expected to continue as more humans migrate to coastal urban areas. Disasters, and as importantly, disaster recovery can affect how native and pest populations will recover. My aim was to improve understanding of disease risk by evaluating the socioecological conditions that have shaped commensal rat recovery and distribution, as well as the pathogens they carry, across New Orleans after Hurricane Katrina. I first estimated relative abundance and distribution of commensal rats from rodent trapping conducted between mid-2014 and early-2017 across 96 sites in 10 areas of …

Reducing The Risk Of Invasive Pathogens To Wildlife Health In The United States, Edward E. Clark Jr., Marshall Meyers, David Eldon Starling, Brent Stewart, Nathan Stone, Gary Tabor, Jeffrey S. White

National Invasive Species Council

Call to Action

In keeping with action items 4.3.1 and 4.3.2 of the 2016–2018 National Invasive Species Council (NISC) Management Plan, the Wildlife Health Task Team of the Invasive Species Advisory Committee (ISAC) was charged with: 1) identifying the major areas of vulnerability to native wildlife from the introduction and spread of invasive pathogens, and 2) making recommendations to address these vulnerabilities, including through potential changes in statute, regulation, policy, or practice of the relevant agencies.

Evaluation Of The Crack Approach For The Control Of Drench Resistance In Sheep Worms, J R. Edwards, Helen Chapman, Jon Dunsmore

Journal of the Department of Agriculture, Western Australia, Series 4

The Department of Agriculture launched the CRACK approach to worm control in September 1985 in response to finding that anthelmintic (drench) resistant worms were present on 68 per cent of a random selection of Western Australian sheep farms.

The high cost of internal parasites in terms of lost production and drench costs, together with the high prevalence of resistant worms of farms, confirmed that changes were needed to existing parasite control measures in sheep.l

A Survey Of Drench Resistance In Sheep Worms, J R. Edwards, R. Wroth, G. C. De Chaneet, R. B. Besier, J. Karlsson, P. W. Morcombe, D. Roberts, G. Dalton-Morgan

Journal of the Department of Agriculture, Western Australia, Series 4

Sheep worms which are resistant to chemical drenches have been detected with increasing freuency is Western Australia's south-western farming areas between 977 and 1980. These worms have anthelmintic resistance and such genetis resistance puts essential internal parasite control practices at risk.

This prompted veterinarians in the Esperance, Albany, Bunbury, Geraldton and Northam areas to survey farms to determine the prevalence of resistance to drenches and to define those sheep management practices which encourage its development.

This article describes the survey which was conducted to assess the extent of drench resistance, what causes its build-up and how it can be controlled …

Drenches For Treatment And Control Of Worms In Sheep : 1969 : Efficiency, Cost And Safety, W A. Halhead, G. De Chaneet

Journal of the Department of Agriculture, Western Australia, Series 4

THERE is a wide variation in the efficiency and cost of drugs for worm control in sheep.

Generally, the higher the efficiency, the greater the cost. Prices are subject to change, and may vary with the amount of drench purchased.

Hydatid Disease In Western Australia, K J. Austen

Journal of the Department of Agriculture, Western Australia, Series 4

BECAUSE hydatid disease is a disease of humans as well as animals every consideration must be given to its control and to the prevention of any possible increase in incidence.

The incidence of hydatids in Western Australia has not, in the past, been very high.

However, the great increase in sheep numbers which has taken place in recent years and which is expected to continue for many years to come, will produce a situation where it could be expected that the incidence of the disease will rise unless stock owners, particularly sheep owners, take appropriate steps to control the tapeworms …

Worms In Sheep. 2. Seasonal Variations In Worm Burdens, R W. Butler

Journal of the Department of Agriculture, Western Australia, Series 4

The first article in this series described the worms which commonly infest sheep in Western Australia and the symptoms caused by heavy infestations.

This article outlines the effects of seasonal changes on worm burdens in sheep.

AS a basis for planning a worm control programme it is essential to have information on the seasonal changes in worm burdens and on the factors which control these.

In this article, the more important of these are considered.

Worms In Sheep. 3. Control Of Worms By Drenching, R W. Butler

Journal of the Department of Agriculture, Western Australia, Series 4

DRENCHING for worm control must be carefully timed in relation to the effect of climatic conditions on the development and survival of worm larvae on the pastures, and the seasonal variation in worm burdens carried by sheep.

These Worms ........ Caused This, F C. Wilkinson

Journal of the Department of Agriculture, Western Australia, Series 4

THE weather had been remarkably pleasant, with an odd shower of rain followed by several warm days.

Just the weather for blowfly troubles, so the owner decided it was time he crutched his breeding flock of 500 ewes.

But as the mob approached the yards trouble was coming

Control Of Lice On Poultry, B R. Vale

Journal of the Department of Agriculture, Western Australia, Series 4

DURING February and March of 1965 some particularly heavy body lice infestations were found on fowls in both deep litter and cage units in Western Australia.

In some instances comparatively new laying cage units were involved.

The most seriously affected flocks showed marked unthriftiness and depressed egg production.

Internal Parasites Of Cattle, J Craig, R. Butler, M. E. Nairn

Journal of the Department of Agriculture, Western Australia, Series 4

Worm parasites can have a most serious effect on cattle, even causing deaths.

This article describes the main parasites of cattle, treatment with modern anthelmintic drugs and the best means of preventing and controlling worm outbreaks.