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Veterinary Infectious Diseases Commons™
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Articles 1 - 17 of 17
Full-Text Articles in Veterinary Infectious Diseases
Sheep Updates 2008 - Contents, Department Of Food And Agriculture, Western Australia
Sheep Updates 2008 - Contents, Department Of Food And Agriculture, Western Australia
Sheep Updates
No abstract provided.
Bovine Viral Diarrhea Virus Multiorgan Infection In Two White-Tailed Deer In Southeastern South Dakota, Christopher C.L. Chase, Lyle J. Braun, Pamela Leslie-Steen, Tanya Graham, Dale Miskimins, Julia F. Ridpath
Bovine Viral Diarrhea Virus Multiorgan Infection In Two White-Tailed Deer In Southeastern South Dakota, Christopher C.L. Chase, Lyle J. Braun, Pamela Leslie-Steen, Tanya Graham, Dale Miskimins, Julia F. Ridpath
Veterinary and Biomedical Sciences Faculty Publications
The susceptibility of wild ruminants, especially cervids, to bovine viral diarrhea virus (BVDV) has remained an enigma. Two white-tailed deer (Odocoileus virginianus) were submitted to the Animal Disease Research and Diagnostic Laboratory (ADRDL) in the fall of 2003 by the South Dakota Game Fish and Parks for chronic wasting disease (CWD) testing. Both animals were CWD negative. The animals were necropsied and histopathology, viral antigen detection, and virus isolation were performed. A noncytopathic (NCP) BVDV was isolated from the lungs and several other tissues of both animals. Formalin-fixed ear notches from both animals were positive for BVDV antigen by immunohistochemistry. …
Tetanus And Rabies Eradication In Pakistan; A Mission Not Impossible, Mohammad Wasay, Ismail A. Khatri, Naseem Salahuddin
Tetanus And Rabies Eradication In Pakistan; A Mission Not Impossible, Mohammad Wasay, Ismail A. Khatri, Naseem Salahuddin
Department of Medicine
No abstract provided.
Brown Dog Tick: Vector For Rocky Mountain Spotted Fever, Craig Levy
Brown Dog Tick: Vector For Rocky Mountain Spotted Fever, Craig Levy
Other Publications in Zoonotics and Wildlife Disease
The brown dog tick, Rhipicephalus sanguineus (Acari: Ixodidae), feeds primarily on dogs and until recently was not known to vector Rocky Mountain spotted fever (RMSF). In 2003–2004, fourteen cases of RMSF in humans occurred in eastern Arizona in the absence of known vectors, the Rocky Mountain wood tick, Dermacentor andersoni, and American dog tick, Dermacentor variabilis. However, health officials found brown dog ticks to be very abundant in areas associated with human cases, and the Centers for Disease Control and Prevention (CDC) implicated that the brown dog tick was responsible for transmitting RMSF. Brown dog ticks occur throughout the United …
Myenteric Neurons Of The Ileum That Express Somatostatin Are A Target Of Prion Neuroinvasion In An Alimentary Model Of Sheep Scrapie, David A. Schneider, Huijun Yan, Lindsay M. Fry, Janet Alverson, Stephen N. White, Katherine I. O'Rourke
Myenteric Neurons Of The Ileum That Express Somatostatin Are A Target Of Prion Neuroinvasion In An Alimentary Model Of Sheep Scrapie, David A. Schneider, Huijun Yan, Lindsay M. Fry, Janet Alverson, Stephen N. White, Katherine I. O'Rourke
Other Publications in Zoonotics and Wildlife Disease
Neuroinvasion of the enteric nervous system by prions is an important step in dissemination to the brain, yet very little is known about the basic process of enteric neuroinvasion. Using an alimentary model of neonatal disease transmission, neuroinvasion by scrapie prions in the ileum of lambs was detected by immunohistochemical staining for the disease-associated form of the prion protein, PrPSc. Odds ratios (OR) were determined for the frequency of PrPSc staining within enteric somata categorized by plexus location (myenteric, submucosal) and neurochemical staining (PGP 9.5, neural nitric oxide synthase, somatostatin, substance P, and vasoactive intestinal polypeptide). PrP …
Scrapie Resistance In Arq Sheep, W. W. Laegreid, M. L. Clawson, M. P. Heaton, B. T. Green, Katherine I. O'Rourke, D. P. Knowles
Scrapie Resistance In Arq Sheep, W. W. Laegreid, M. L. Clawson, M. P. Heaton, B. T. Green, Katherine I. O'Rourke, D. P. Knowles
Other Publications in Zoonotics and Wildlife Disease
Variation in the ovine prion protein amino acid sequence influences scrapie progression, with sheep homozygous for A136R154Q171 considered susceptible. This study examined the association of survival time of scrapie-exposed ARQ sheep with variation elsewhere in the ovine prion gene. Four single nucleotide polymorphism alleles were associated with prolonged survival. One nonsynonymous allele (T112) was associated with an additional 687 days of survival for scrapie-exposed sheep compared to M112 sheep (odds ratio, 42.5; P = 0.00014). The only two sheep homozygous for T112 (TARQ) did not develop scrapie, suggesting that the allelic effect may be additive. …
Avances En La Producción De Una Vacuna Viva Contra Yersinia Pseudotuberculosis Y Evaluación De Su Efectividad Mediante Un Ensayo De Infección Experimental En Cavia Porcellus, María Angélica Amaya Garzón, Liliana Calle Londoño
Avances En La Producción De Una Vacuna Viva Contra Yersinia Pseudotuberculosis Y Evaluación De Su Efectividad Mediante Un Ensayo De Infección Experimental En Cavia Porcellus, María Angélica Amaya Garzón, Liliana Calle Londoño
Medicina Veterinaria
La yersiniosis es una enfermedad infectocontagiosa, causante de alta morbimortalidad en los cuyes (Cavia porcellus), los cuales son una especie de gran importancia en la región andina de Sur América y en especial en el departamento de Nariño en Colombia, donde juega un papel importante en el desarrollo socioeconómico de la población campesina. En el presente trabajo de investigación se pretende obtener una vacuna viva atenuada por pases sucesivos en macrófagos. Esta vacuna permitirá en el futuro disminuir la prevalencia de esta enfermedad y en consecuencia disminuir los costos ocasionados por tratamientos y mortalidad, simultáneamente se estará mejorando la productividad …
Estudio Histopatológico De Dermatopatías No Neoplásicas En El Perro, Liliana Jiménez González
Estudio Histopatológico De Dermatopatías No Neoplásicas En El Perro, Liliana Jiménez González
Medicina Veterinaria
Las dermatopatías son unas de las condiciones clínicas de mayor presentación en la clínica de pequeños animales, las lesiones no neoplásicas que se evidencian en la piel van desde alopecia, eritema, prurito, hasta pápulas, vesículas y pústulas. Estas lesiones se presentan como el resultado de varios factores y agentes etiológicos, por está razón se hace necesario utilizar herramientas diagnósticas como son impresiones, citologías, cultivos y biopsias. Estas últimas permiten un mayor acercamiento a las posibles causas de las reacciones tisulares porque proveen imágenes de las estructuras de la piel y además es posible realizar coloraciones diferenciales para llegar ya sea …
Evaluación De La Relación Que Tiene El Estrés En Los Gatos Indoor Frente A La Presentación De La Cistitis Intersticial Felina, Kerby Andrea Vivas Alba, Raquel Sofia Vargas Quevedo
Evaluación De La Relación Que Tiene El Estrés En Los Gatos Indoor Frente A La Presentación De La Cistitis Intersticial Felina, Kerby Andrea Vivas Alba, Raquel Sofia Vargas Quevedo
Medicina Veterinaria
En la actualidad el gato es una de las especies que está obteniendo una creciente preferencia como mascota, en condiciones de confinamiento en el hogar; bajo una reducida o nula salida a un medio exterior denominándose así al animal como (GATO INDOOR). Esta condición de confinamiento pueden volverse un problema para los gatos ya que aquellos que carecen de un enriquecimiento ambiental propios de la especie, o se les expone a cambios bruscos e inesperados en su entorno socio – ambiental los enfrenta a niveles de estrés que los predispone a desarrollar y manifestar cambios de comportamiento y desórdenes fisiológicos …
Estudio De La Paratuberculosis En Un Rebaño De Ovinos De La Sabana De Bogotá Mediante La Utilización De Tres Técnicas Diagnósticas, Luisa Fernanda Mancipe Jiménez, José Luis Sánchez Cárdenas
Estudio De La Paratuberculosis En Un Rebaño De Ovinos De La Sabana De Bogotá Mediante La Utilización De Tres Técnicas Diagnósticas, Luisa Fernanda Mancipe Jiménez, José Luis Sánchez Cárdenas
Medicina Veterinaria
Desde 1895, cuando la paratuberculosis fue descrita como una entidad clínica por Johne y Frothingham, el estudio de la enfermedad ha reunido un gran número de seguidores los cuales han empleado gran parte de su vida en aclarar varios aspectos de la enfermedad. La cronicidad y la resistencia a las medidas terapéuticas tiene todos los esfuerzos concentrados en los mecanismos de transmisión de la enfermedad, la influencia de los factores de riesgo, la identificación serológica de animales en etapa subclínica y otros diagnósticos tempranos. En los últimos años, los estudios en la patogénesis y en las técnicas de diagnóstico de …
Ecological Factors Associated With West Nile Virus Transmission, Northeastern United States, Heidi E. Brown, James E. Childs, Maria A. Diuk-Wasser, Durland Fish
Ecological Factors Associated With West Nile Virus Transmission, Northeastern United States, Heidi E. Brown, James E. Childs, Maria A. Diuk-Wasser, Durland Fish
Other Publications in Zoonotics and Wildlife Disease
Since 1999, West Nile virus (WNV) disease has affected the northeastern United States. To describe the spatial epidemiology and identify risk factors for disease incidence, we analyzed 8 years (1999–2006) of county-based human WNV disease surveillance data. Among the 56.6 million residents in 8 northeastern states sharing primary enzootic vectors, we found 977 cases. We controlled for population density and potential bias from surveillance and spatial proximity. Analyses demonstrated significant spatial spreading from 1999 through 2004 (p2 = 0.16). A significant trend was apparent among increasingly urban counties; county quartiles with the least (0.75 cases/100,000 residents) than counties with the …
Prion Gene (Prnp) Haplotype Variation In United States Goat Breeds, Stephen N. White, Lynn Herrmann-Hoesing, Katherine I. O'Rourke, Daniel Waldron, Joan Rowe, Janet Alverson
Prion Gene (Prnp) Haplotype Variation In United States Goat Breeds, Stephen N. White, Lynn Herrmann-Hoesing, Katherine I. O'Rourke, Daniel Waldron, Joan Rowe, Janet Alverson
Other Publications in Zoonotics and Wildlife Disease
Scrapie eradication efforts cost 18 million dollars annually in the United States and rely heavily upon PRNP genotyping of sheep. Genetic resistance might reduce goat scrapie and limit the risk of goats serving as a scrapie reservoir, so PRNP coding sequences were examined from 446 goats of 10 breeds, 8 of which had not been previously examined at PRNP. The 10 observed alleles were all related to one of two central haplotypes by a single amino acid substitution. At least five of these alleles (M142, R143, S146, H154, and K222) have been associated with increased incubation time or decreased …
A Species Barrier Limits Transmission Of Chronic Wasting Disease To Mink (Mustela Vison), Robert D. Harrington, Timothy V. Baszler, Katherine I. O'Rourke, David A. Schneider, Terry R. Spraker, H. Denny Liggitt, Donald P. Knowles
A Species Barrier Limits Transmission Of Chronic Wasting Disease To Mink (Mustela Vison), Robert D. Harrington, Timothy V. Baszler, Katherine I. O'Rourke, David A. Schneider, Terry R. Spraker, H. Denny Liggitt, Donald P. Knowles
Other Publications in Zoonotics and Wildlife Disease
Transmissible mink encephalopathy (TME) occurs as sporadic outbreaks associated with ingestion of feed presumably contaminated with some type of prion disease. Mink lack a species barrier to primary oral challenge with bovine spongiform encephalopathy, whereas they have a barrier to such challenge with scrapie. We investigated whether mink have a species barrier to chronic wasting disease (CWD) by performing primary intracerebral (IC) and primary oral challenge with CWD-positive elk brain. Primary IC challenge resulted in clinical disease in two of eight mink at 31–33 months incubation. Affected mink had spongiform vacuolation and astrocytosis within the central nervous system and immunoreactivity …
Small-Ruminant Lentivirus Enhances PrpSc Accumulation In Cultured Sheep Microglial Cells, James B. Stanton, Donald P. Knowles, Katherine I. O'Rourke, Lynn M. Herrmann-Hoesing, Bruce A. Mathison, Timothy V. Baszler
Small-Ruminant Lentivirus Enhances PrpSc Accumulation In Cultured Sheep Microglial Cells, James B. Stanton, Donald P. Knowles, Katherine I. O'Rourke, Lynn M. Herrmann-Hoesing, Bruce A. Mathison, Timothy V. Baszler
Other Publications in Zoonotics and Wildlife Disease
Sheep scrapie is the prototypical transmissible spongiform encephalopathy (prion disease), which has a fundamental pathogenesis involving conversion of normal cellular prion protein (PrPC [C superscript stands for cellular]) to disease-associated prion protein (PrPSc [Sc superscript stands for sheep scrapie]). Sheep microglial cell cultures, derived from a prnp 136VV/171QQ near-term fetal brain, were developed to study sheep scrapie in the natural host and to investigate potential cofactors in the prion conversion process. Two culture systems, a primary cell culture and a cell line transformed with the large T antigen of simian virus 40, were developed, and both were identified …
Chronic Wasting Disease In A Wisconsin White-Tailed Deer Farm, Delwyn P. Keane, Daniel J. Barr, Phillip N. Bochsler, S. Mark Hall, Thomas Gidlewski, Katherine I. O'Rourke, Terry R. Spraker, Michael D. Samuel
Chronic Wasting Disease In A Wisconsin White-Tailed Deer Farm, Delwyn P. Keane, Daniel J. Barr, Phillip N. Bochsler, S. Mark Hall, Thomas Gidlewski, Katherine I. O'Rourke, Terry R. Spraker, Michael D. Samuel
Other Publications in Zoonotics and Wildlife Disease
In September 2002, chronic wasting disease (CWD), a prion disorder of captive and wild cervids, was diagnosed in a white-tailed deer (Odocoileus virginianus) from a captive farm in Wisconsin. The facility was subsequently quarantined, and in January 2006 the remaining 76 deer were depopulated. Sixty animals (79%) were found to be positive by immunohistochemical staining for the abnormal prion protein (PrPCWD) in at least one tissue; the prevalence of positive staining was high even in young deer. Although none of the deer displayed clinical signs suggestive of CWD at depopulation, 49 deer had considerable accumulation of …
A Collaborative Canadian–United Kingdom Evaluation Of An Immunohistochemistry Protocol To Diagnose Bovine Spongiform Encephalopathy, Lisa Manning, Katherine I. O'Rourke, Donald P. Knowles, Sarah A. Marsh, Yvonne I. Spencer, Estella Moffat, Gerald A. H. Wells, Stefanie Czub
A Collaborative Canadian–United Kingdom Evaluation Of An Immunohistochemistry Protocol To Diagnose Bovine Spongiform Encephalopathy, Lisa Manning, Katherine I. O'Rourke, Donald P. Knowles, Sarah A. Marsh, Yvonne I. Spencer, Estella Moffat, Gerald A. H. Wells, Stefanie Czub
Other Publications in Zoonotics and Wildlife Disease
Collaboration was established in 2001 to evaluate a commercially available immunohistochemistry assay kit for the detection of bovine spongiform encephalopathy (BSE) disease–associated prion protein in formic acid–treated formalin-fixed samples of bovine brain. The kit protocol was evaluated at the National Centre for Foreign Animal Diseases (Winnipeg, Canada) and the Veterinary Laboratories Agency (Weybridge, U.K.). The U.K. laboratory provided paraffin-embedded blocks of brainstem (medulla oblongata at the level of the obex) from 100 positive cases defined by clinical signs and histopathology, and 100 clinically suspect but BSE-negative samples defined by histopathology and immunohistochemistry with anti-PrP monoclonal antibody R145. The Canadian laboratory …
Experimental Transmission Of Chronic Wasting Disease (Cwd) Of Elk (Cervus Elaphus Nelsoni), White-Tailed Deer (Odocoileus Virginianus), And Mule Deer (Odocoileus Hemionus Hemionus) To White-Tailed Deer By Intracerebral Route, A. N. Hamir, J. A. Richt, J. M. Miller, R. A. Kunkle, S. M. Hall, E. M. Nicholson, Katherine I. O'Rourke, J. J. Greenlee, E. S. Williams
Experimental Transmission Of Chronic Wasting Disease (Cwd) Of Elk (Cervus Elaphus Nelsoni), White-Tailed Deer (Odocoileus Virginianus), And Mule Deer (Odocoileus Hemionus Hemionus) To White-Tailed Deer By Intracerebral Route, A. N. Hamir, J. A. Richt, J. M. Miller, R. A. Kunkle, S. M. Hall, E. M. Nicholson, Katherine I. O'Rourke, J. J. Greenlee, E. S. Williams
Other Publications in Zoonotics and Wildlife Disease
To compare clinical and pathologic findings of chronic wasting disease (CWD) in a natural host, 3 groups (n = 5) of white-tailed deer (WTD) fawns were intracerebrally inoculated with a CWD prion of WTD, mule deer, or elk origin. Three other uninoculated fawns served as controls. Approximately 10 months postinoculation (MPI), 1 deer from each of the 3 inoculated groups was necropsied and their tissues were examined for lesions of spongiform encephalopathy (SE) and for the presence of abnormal prion protein (PrPd) by immunohistochemistry (IHC) and Western blot (WB). The remaining deer were allowed to live until …