Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Large or Food Animal and Equine Medicine

Evaluating Viability, Developmental Competence, And Chromatin Configurations Of Cryopreserved Equine Oocytes, Tricia Adams Oct 2024

Evaluating Viability, Developmental Competence, And Chromatin Configurations Of Cryopreserved Equine Oocytes, Tricia Adams

LSU Doctoral Dissertations

Assisted reproduction technology and the use of specialized laboratories have increased in the horse breeding industry over the last decade. This expansion has highlighted the inability to routinely cryopreserve oocytes and preserve female genetics. Oocyte vitrification, a cryopreservation process, continues to be characterized as an experimental procedure in horses. The goal of this dissertation was to evaluate the viability, developmental competence, and nuclear structures of cryopreserved equine oocytes to illuminate potential areas of improvement in the vitrification process. Oocytes were collected from abattoir derived ovaries and exposed to either varying lengths of in vitro maturation (IVM) or pretreated with a …


The Pathophysiology Of Equine Glandular Gastric Disease: Investigating The Role Of The Mucosal Microbiome And Bile Acid Reflux, Linda Paul Aug 2023

The Pathophysiology Of Equine Glandular Gastric Disease: Investigating The Role Of The Mucosal Microbiome And Bile Acid Reflux, Linda Paul

LSU Doctoral Dissertations

Equine glandular gastric disease (EGGD) is a common disease of athletic horses that can affect performance and welfare. Clinical signs are non-specific and diagnosis is made using gastroscopy after a prolonged fasting period. Effective prevention and treatment strategies for EGGD are lacking despite its widespread prevalence and negative effects. The goal of this research was to investigate the pathophysiology of EGGD. Objectives included: 1) compare the gastric glandular mucosal microbiome in horses with and without EGGD, 2) assess the influence of dietary and management factors on the gastric microbiome, and 3) evaluate the pyloric gastric fluid bile acid profile in …


Embryo Development And Reproductive Parameters Of Aluteal Cycles In Mares, Chun Kuen Mak Jul 2021

Embryo Development And Reproductive Parameters Of Aluteal Cycles In Mares, Chun Kuen Mak

LSU Doctoral Dissertations

Progestagen is crucial for regulating early pregnancy in most mammalian species, including the horse. This dissertation research sought to elucidate the effect of endogenous and exogenous progestagens on the early development of equine embryos and to characterize reproductive parameters in the subsequent estrus using a prostaglandin F2α-induced hypoluteal environment, namely the aluteal pregnancy model. The first chapter reviewed the life cycle of the corpus luteum and its progesterone secretory function in mares. The existing literature supports the notion that the early developing corpus luteum is responsive to prostaglandin F2α, and complete luteolysis or prevention of luteal …