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Comparative and Laboratory Animal Medicine Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Comparative and Laboratory Animal Medicine
Enhancing The Visual Environment Of Indoor Housed Laboratory Cynomolgus Macaques (Macaca Fascicularis) To Reduce Stress And Maladaptive Behavior, Jeannine C. Rodgers
Enhancing The Visual Environment Of Indoor Housed Laboratory Cynomolgus Macaques (Macaca Fascicularis) To Reduce Stress And Maladaptive Behavior, Jeannine C. Rodgers
Theses and Dissertations
Nonhuman primates housed in indoor laboratory environments are generally exposed to nondescript background visual stimuli. This environment is not ideal for species whose primary sensory modality is visual. To provide a more naturalistic visual environment that would potentially improve their welfare, this study assessed the efficacy of a passive natural visual stimulus in the reduction of stress and stereotypy and agonistic behaviors in a cohort of four (2 male, 2 female) Cynomolgus macaques (Macaca fascicularis) housed in an indoor laboratory facility in New York City. The macaques were exposed to four different videos depicting scenes of natural landscapes that were …
A History Of The Development Of Alternatives To Animals In Research And Testing, John Parascandola
A History Of The Development Of Alternatives To Animals In Research And Testing, John Parascandola
New Directions in the Human-Animal Bond
Growing public interest in animal welfare issues in recent decades has prompted increased attention to the efforts to develop alternative, nonanimal methods for use in biomedical research and product testing. In A History of the Development of Alternatives to Animals in Research and Testing, the first book-length study of the subject, John Parascandola traces the history of the concept of alternatives to the use of animals in research and testing in Britain and the United States from its beginnings until it had become firmly established in the scientific and animal protection communities by the end of the 1980s. This …
Probiotic Limosilactobacillus Reuteri Dsm 17938 Changes Foxp3 Deficiency-Induced Dyslipidemia And Chronic Hepatitis In Mice, Erini Nessim Kostandy, Ji Ho Suh, Xiangjun Tian, Beanna Okeugo, Erin Rubin, Sara Shirai, Meng Luo, Christopher M Taylor, Kang Ho Kim, J Marc Rhoads, Yuying Liu
Probiotic Limosilactobacillus Reuteri Dsm 17938 Changes Foxp3 Deficiency-Induced Dyslipidemia And Chronic Hepatitis In Mice, Erini Nessim Kostandy, Ji Ho Suh, Xiangjun Tian, Beanna Okeugo, Erin Rubin, Sara Shirai, Meng Luo, Christopher M Taylor, Kang Ho Kim, J Marc Rhoads, Yuying Liu
Faculty, Staff and Student Publications
The probiotic Limosilactobacillus reuteri DSM 17938 produces anti-inflammatory effects in scurfy (SF) mice, a model characterized by immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (called IPEX syndrome in humans), caused by regulatory T cell (Treg) deficiency and is due to a Foxp3 gene mutation. Considering the pivotal role of lipids in autoimmune inflammatory processes, we investigated alterations in the relative abundance of lipid profiles in SF mice (± treatment with DSM 17938) compared to normal WT mice. We also examined the correlation between plasma lipids and gut microbiota and circulating inflammatory markers. We noted a significant upregulation of plasma lipids …