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Veterinary Medicine Commons

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2019

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Articles 91 - 120 of 387

Full-Text Articles in Veterinary Medicine

Transmission Dynamics Of Toxoplasma Gondii In Arctic Foxes (Vulpes Lagopus): A Long-Term Mark-Recapture Serologic Study At Karrak Lake, Nunavut, Canada, Emilie Bouchard, Stacey A. Elmore, Ray T. Alisauskas, Gustaf Samelius, Alvin A. Gajadhar, Keaton Schmidt, Sasha Ross, Emily J. Jenkins Jul 2019

Transmission Dynamics Of Toxoplasma Gondii In Arctic Foxes (Vulpes Lagopus): A Long-Term Mark-Recapture Serologic Study At Karrak Lake, Nunavut, Canada, Emilie Bouchard, Stacey A. Elmore, Ray T. Alisauskas, Gustaf Samelius, Alvin A. Gajadhar, Keaton Schmidt, Sasha Ross, Emily J. Jenkins

United States Department of Agriculture Wildlife Services: Staff Publications

Transmission dynamics of Toxoplasma gondii, a parasite of importance for wildlife and human health, are enigmatic in the Arctic tundra, where free-ranging wild and domestic felid definitive hosts are absent and rarely observed, respectively. Through a multiyear mark-recapture study (2011– 17), serosurveillance was conducted to investigate transmission of T. gondii in Arctic foxes (Vulpes lagopus) in the Karrak Lake region, Nunavut, Canada. Sera from adult foxes and fox pups were tested for antibodies to T. gondii by using serologic methods, including the indirect fluorescent antibody test, direct agglutination test, and modified agglutination test. The overall seroprevalence was 39% in adults …


Not All Surveillance Data Are Created Equal—A Multi‐Method Dynamic Occupancy Approach To Determine Rabies Elimination From Wildlife, Amy J. Davis, Jordona D. Kirby, Richard B. Chipman, Kathleen M. Nelson, Tatiana Xifara, Colleen T. Webb, Ryan Wallace, Amy T. Gilbert, Kim M. Pepin Jul 2019

Not All Surveillance Data Are Created Equal—A Multi‐Method Dynamic Occupancy Approach To Determine Rabies Elimination From Wildlife, Amy J. Davis, Jordona D. Kirby, Richard B. Chipman, Kathleen M. Nelson, Tatiana Xifara, Colleen T. Webb, Ryan Wallace, Amy T. Gilbert, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

1. A necessary component of elimination programmes for wildlife disease is effective surveillance. The ability to distinguish between disease freedom and non‐detection can mean the difference between a successful elimination campaign and new epizootics. Understanding the contribution of different surveillance methods helps to optimize and better allocate effort and develop more effective surveillance programmes.

2. We evaluated the probability of rabies virus elimination (disease freedom) in an enzootic area with active management using dynamic occupancy modelling of 10 years of raccoon rabies virus (RABV) surveillance data (2006–2015) collected from three states in the eastern United States. We estimated detection probability …


Impact Of Beta-Adrenergic Agonist Supplementation And Heat Stress On The Microbiome And Gastrointestinal Transcriptome Of Sheep, Erin Margaret Duffy Jul 2019

Impact Of Beta-Adrenergic Agonist Supplementation And Heat Stress On The Microbiome And Gastrointestinal Transcriptome Of Sheep, Erin Margaret Duffy

Department of Animal Science: Dissertations, Theses, and Student Research

Improving animal growth and efficiency are critical points of research as the world’s population and demand for agriculture products increase. Therefore, adaptions or changes in the gut are of interest to maximize growth efficiency and wellbeing of livestock. The gastrointestinal tract of the rumen plays many critical roles with the assistance of the associated microbial community. One way to improve animal performance is supplementation of β-adrenergic agonists (β-AA) which are commonly fed to cattle during the last 20-40 days of the finishing period, improving muscle growth by decreasing adipose deposition and increasing muscle accretion. Two β-AA, Ractopamine HCl (β1-AA) and …


Survival, Fidelity, And Dispersal Of Double-Crested Cormorants On Two Lake Michigan Islands, Christopher R. Ayers, Katie C. Hanson-Dorr, Ken Stromborg, Todd W. Arnold, Jacob S. Ivan, Brian S. Dorr Jun 2019

Survival, Fidelity, And Dispersal Of Double-Crested Cormorants On Two Lake Michigan Islands, Christopher R. Ayers, Katie C. Hanson-Dorr, Ken Stromborg, Todd W. Arnold, Jacob S. Ivan, Brian S. Dorr

United States Department of Agriculture Wildlife Services: Staff Publications

Colony fidelity and dispersal can have important consequences on the population dynamics of colonial-nesting birds. We studied survival and inter-colony movements of Double-crested Cormorants (Phalacrocorax auritus; cormorants) nesting at Spider and Pilot islands, located 9 km apart in western Lake Michigan, during 2008–2014. We used live resighting and dead recovery data from both colonies, plus dead recoveries from throughout North America, in a multistate live and dead encounter model to estimate annual survival, inter-colony movements, plus temporary and permanent emigration to unmonitored sites. Annual survival averaged 0.37 (annual process variation, ˆ = 0.07) for hatch-year, 0.78 (ˆ= 0.08) for secondyear, …


Use Of Unmanned Aircraft Systems (Uas) And Multispectral Imagery For Quantifying Agricultural Areas Damaged By Wild Pigs, Justin W. Fischer, Kelsey Greiner, Mark W. Lutman, Bryson L. Webber, Kurt C. Vercauteren Jun 2019

Use Of Unmanned Aircraft Systems (Uas) And Multispectral Imagery For Quantifying Agricultural Areas Damaged By Wild Pigs, Justin W. Fischer, Kelsey Greiner, Mark W. Lutman, Bryson L. Webber, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) cause extensive damage to agricultural crops, resulting in lost production and income. A major challenge associated with assessing damage to crops is locating and quantifying damaged areas within agricultural fields. We evaluated a novel method using multispectral high-resolution aerial imagery, collected from sensors mounted on unmanned aircraft systems (UAS), and feature extraction techniques to detect and map areas of corn fields damaged by wild pigs in southern Missouri, USA. Damaged areas were extracted from orthomosaics using visible and near-infrared band combinations, an object-based classification approach, and hierarchical learning cycles. To validate estimates we also collected ground …


Confronting Models With Data: The Challenges Of Estimating Disease Spillover, Paul C. Cross, Diann J. Prosser, Andrew M. Ramey, Ephraim M. Hanks, Kim M. Pepin Jun 2019

Confronting Models With Data: The Challenges Of Estimating Disease Spillover, Paul C. Cross, Diann J. Prosser, Andrew M. Ramey, Ephraim M. Hanks, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

For pathogens known to transmit across host species, strategic investment in disease control requires knowledge about where and when spillover transmission is likely. One approach to estimating spillover is to directly correlate observed spillover events with covariates. An alternative is to mechanistically combine information on host density, distribution and pathogen prevalence to predict where and when spillover events are expected to occur. We use several case studies at the wildlife–livestock disease interface to highlight the challenges, and potential solutions, to estimating spatiotemporal variation in spillover risk. Datasets on multiple host species often do not align in space, time or resolution, …


Typha (Cattail) Invasion In North American Wetlands: Biology, Regional Problems, Impacts, Ecosystem Services, And Management, Sheel Bansal, Shane C. Lishawa, Sue Newman, Brian A. Tangen, Douglas Wilcox, Dennis Albert, Michael J. Anteau, Michael J. Chimney, Ryann L. Cressey, Edward Dekeyser, Kenneth J. Elgersma, Sarah A. Finkelstein, Joanna Freeland, Richard Grosshans, Page E. Klug, Daniel J. Larkin, Beth A. Lawrence, George Linz, Joy Marburger, Gregory Noe, Clint Otto, Nicholas Reo, Jennifer Richards, Curtis Richardson, Leroy Rodgers, Amy J. Schrank, Dan Svedarsky, Steven Travis, Nancy Tuchman, Lisamarie Windham-Myers Jun 2019

Typha (Cattail) Invasion In North American Wetlands: Biology, Regional Problems, Impacts, Ecosystem Services, And Management, Sheel Bansal, Shane C. Lishawa, Sue Newman, Brian A. Tangen, Douglas Wilcox, Dennis Albert, Michael J. Anteau, Michael J. Chimney, Ryann L. Cressey, Edward Dekeyser, Kenneth J. Elgersma, Sarah A. Finkelstein, Joanna Freeland, Richard Grosshans, Page E. Klug, Daniel J. Larkin, Beth A. Lawrence, George Linz, Joy Marburger, Gregory Noe, Clint Otto, Nicholas Reo, Jennifer Richards, Curtis Richardson, Leroy Rodgers, Amy J. Schrank, Dan Svedarsky, Steven Travis, Nancy Tuchman, Lisamarie Windham-Myers

United States Department of Agriculture Wildlife Services: Staff Publications

Typha is an iconic wetland plant found worldwide. Hybridization and anthropogenic disturbances have resulted in large increases in Typha abundance in wetland ecosystems throughout North America at a cost to native floral and faunal biodiversity. As demonstrated by three regional case studies, Typha is capable of rapidly colonizing habitats and forming monodominant vegetation stands due to traits such as robust size, rapid growth rate, and rhizomatic expansion. Increased nutrient inputs into wetlands and altered hydrologic regimes are among the principal anthropogenic drivers of Typha invasion. Typha is associated with a wide range of negative ecological impacts to wetland and agricultural …


Neurostimulator With Waveforms Inspired By Nature For Wearable Electro-Acupuncture, Jose Aquiles Parodi Amaya Jun 2019

Neurostimulator With Waveforms Inspired By Nature For Wearable Electro-Acupuncture, Jose Aquiles Parodi Amaya

LSU Doctoral Dissertations

The work presented here has 3 goals: establish the need for novel neurostimulation waveform solutions through a literature review, develop a neurostimulation pulse generator, and verify the operation of the device for neurostimulation applications.

The literature review discusses the importance of stimulation waveforms on the outcomes of neurostimulation, and proposes new directions for neurostimulation research that would help in improving the reproducibility and comparability between studies.

The pulse generator circuit is then described that generates signals inspired by the shape of excitatory or inhibitory post-synaptic potentials (EPSP, IPSP). The circuit analytical equations are presented, and the effects of the circuit …


Failure Of Oxysterols Such As Lanosterol To Restore Lens Clarity From Cataracts, Damian M. Daszynski, Puttur Santhoshkumar, Ashutosh S. Phadte, K. Krishna Sharma, Haizhen A. Zhong, Marjorie F. Lou, Peter F. Kador Jun 2019

Failure Of Oxysterols Such As Lanosterol To Restore Lens Clarity From Cataracts, Damian M. Daszynski, Puttur Santhoshkumar, Ashutosh S. Phadte, K. Krishna Sharma, Haizhen A. Zhong, Marjorie F. Lou, Peter F. Kador

School of Veterinary and Biomedical Sciences: Faculty Publications

The paradigm that cataracts are irreversible and that vision from cataracts can only be restored through surgery has recently been challenged by reports that oxysterols such as lanosterol and 25-hydroxycholesterol can restore vision by binding to αB-crystallin chaperone protein to dissolve or disaggregate lenticular opacities. To confirm this premise, in vitro rat lens studies along with human lens protein solubilization studies were conducted. Cataracts were induced in viable rat lenses cultured for 48 hours in TC-199 bicarbonate media through physical trauma, 10 mM ouabain as Na+/K+ ATPase ion transport inhibitor, or 1 mM of an experimental compound that induces water …


Extreme Site Fidelity As An Optimal Strategy In An Unpredictable And Homogeneous Environment, Brian D. Gerber, Mevin B. Hooten, Christopher P. Peck, Mindy B. Rice, James H. Gammonley, Anthony D. Apa, Amy J. Davis Jun 2019

Extreme Site Fidelity As An Optimal Strategy In An Unpredictable And Homogeneous Environment, Brian D. Gerber, Mevin B. Hooten, Christopher P. Peck, Mindy B. Rice, James H. Gammonley, Anthony D. Apa, Amy J. Davis

United States Department of Agriculture Wildlife Services: Staff Publications

1. Animal site fidelity structures space use, population demography and ultimately gene flow. Understanding the adaptive selection for site fidelity patterns provides a mechanistic understanding to both spatial and population processes. This can be achieved by linking space use with environmental variability (spatial and temporal) and demographic parameters. However, rarely is the environmental context that drives the selection for site fidelity behaviour fully considered.

2. We use ecological theory to understand whether the spatial and temporal variability in breeding site quality can explain the site fidelity behaviour and demographic patterns of Gunnison sage‐grouse (Centrocercus minimus). We examined female site fidelity …


The Benefits Of Lasix For Exercise-Induced Pulmonary Hemorrhage: 50 Years Of Science And Clinical Experience, Kimberly Brewer, Clara Fenger, Thomas Tobin Jun 2019

The Benefits Of Lasix For Exercise-Induced Pulmonary Hemorrhage: 50 Years Of Science And Clinical Experience, Kimberly Brewer, Clara Fenger, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

No abstract provided.


Evaluating The Epidemiology And Management Of Bovine Congestive Heart Failure, Adam Bassett Jun 2019

Evaluating The Epidemiology And Management Of Bovine Congestive Heart Failure, Adam Bassett

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

A form of congestive heart failure is increasingly reported as a cause of death in feedlot cattle located at moderate altitude (≤ 1,524 m.). Significant knowledge gaps exist in the epidemiology and management of this form of bovine congestive heart failure (BCHF) regarding frequency and timing of BCHF cases and ways in which beef cattle producers and veterinarians can mitigate this condition. These knowledge gaps present major barriers to understanding the mechanism of BCHF and mitigating the consequences of BCHF. The purpose of this thesis is to summarize current knowledge about BCHF, define gaps in knowledge for which more research …


Epidemiology Of Characteristics And Risk Factors For Overweight In Cats Visiting An Animal Hospital In Bangkok, Thailand, Vachira Hunprasit, Chaiyot Tanrattana, Siwaporn Pengpis Jun 2019

Epidemiology Of Characteristics And Risk Factors For Overweight In Cats Visiting An Animal Hospital In Bangkok, Thailand, Vachira Hunprasit, Chaiyot Tanrattana, Siwaporn Pengpis

The Thai Journal of Veterinary Medicine

A cross-sectional study aimed to estimate the prevalence and to investigate the characteristics of overweight/obese cats visiting an animal hospital in Bangkok, Thailand. Electronic medical records of feline patient visiting the Small Animal Teaching Hospital, Chulalongkorn University between January 1, 2017 and December 31, 2017 were reviewed. The cat’s information included age, breed, sex, neutering status and body condition score. Associated demographic factors and overweight/obesity using idealweight as a reference was performed by logistic regression. The prevalence of feline overweight/obesity was 8.1% (95%CI: 7.4% - 8.9%). From the multivariable logistic regression, age, sex, neutering status, breed and interaction of age …


Efficacy Of Ultrasonic Dissection Device In Staphylectomy Surgery In Brachycephalic Airway Obstructive Syndrome (Baos) Dogs, Sunisa Thunyodom, Marissak Kalpravidh, Chanin Kalpravidh, Wijit Banlunara, Pasakorn Brikshavana Jun 2019

Efficacy Of Ultrasonic Dissection Device In Staphylectomy Surgery In Brachycephalic Airway Obstructive Syndrome (Baos) Dogs, Sunisa Thunyodom, Marissak Kalpravidh, Chanin Kalpravidh, Wijit Banlunara, Pasakorn Brikshavana

The Thai Journal of Veterinary Medicine

The ultrasonic scalpel instrument was compared with the conventional staphylectomy technique in elongated soft palate surgery in twenty brachycephalic airway obstructive syndrome (BAOS) canines. Patients were randomly divided into the conventional incisional and ultrasonic scalpel group. Operation time (minute), bleeding volume (ml), respiratory distress score, postoperative complications score, pain scores, epithelialization score and inflammatory score were assessed. Two weeks after surgery, soft palates tissues were biopsied from 7 conventional surgery dogs and 8 ultrasonic dissection device applied dogs. The operation time and bleeding volume in the conventional surgery group were significantly higher than that in conventional group (P<0.01 and P<0.001, respectively). In addition, the respiratory distress score was significantly higher in the conventional surgery group compared with the ultrasonic dissection device group on day 3 and day 28 post-operation (P<0.05). There were no significantly different postoperative complication scores, pain scores or inflammatory scores between two groups. The epithelialization score of the UD was significantly higher than that of the conventional group (P<0.05). The ultrasonic dissection device is user friendly, has decreased surgical time, complete hemostasis and provides fewer postoperative complications. The ultrasonic dissection device is recommended in high-risk patients such as those displaying senility, chronic inflammation, or bleeding disorders.


The Use Of Geospatial Modeling And Novel Diagnostics To Detect And Map Risk Factors Of Soil-Transmitted Helminths In Feira De Santana, Brazil, Ryan Harry Avery May 2019

The Use Of Geospatial Modeling And Novel Diagnostics To Detect And Map Risk Factors Of Soil-Transmitted Helminths In Feira De Santana, Brazil, Ryan Harry Avery

LSU Doctoral Dissertations

Soil-transmitted helminth (STH) infections impact billions of people worldwide. The traditional STH control approach is a morbidity control strategy implementing mass drug administration (MDA) programs targeting school-aged children (SAC). In Brazil, this control strategy has decreased STH prevalence to less than 20% in most of the country and providing an opportunity to transition from the morbidity control program and towards a surveillance and response system geared towards STH elimination. Surveillance and response systems geared towards elimination require the implementation higher accuracy diagnostics to detect infection in low-transmission communities, surveillance of entire households, high-resolution modeling at the household-habitat scale, and targeted …


Ecological Interventions To Prevent And Manage Zoonotic Pathogen Spillover, Susanne H. Sokolow, Nicole Nova, Kim M. Pepin, Alison J. Peel, Juliet R.C. Pulliam, Kezia Manlove, Paul C. Cross, Daniel J. Becker, Raina K. Plowright, Hamish Mccallum, Giulio A. De Leo May 2019

Ecological Interventions To Prevent And Manage Zoonotic Pathogen Spillover, Susanne H. Sokolow, Nicole Nova, Kim M. Pepin, Alison J. Peel, Juliet R.C. Pulliam, Kezia Manlove, Paul C. Cross, Daniel J. Becker, Raina K. Plowright, Hamish Mccallum, Giulio A. De Leo

United States Department of Agriculture Wildlife Services: Staff Publications

Spillover of a pathogen from awildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control. Accelerating spillover owing to environmental change requires effective, affordable, durable and scalable solutions that fully harness the complex processes involved in cross-species pathogen spillover.

This article is part of the theme …


Scavenging In The Anthropocene: Human Impact Drives Vertebrate Scavenger Species Richness At A Global Scale, Esther Sebastián‐González, Jomar Magalhães Barbosa, Juan M. Pérez‐García, Zebensui Morales‐Reyes, Francisco Botella, Pedro P. Olea, Patricia Mateo‐Tomás, Marcos Moleón, Fernando Hiraldo, Eneko Arrondo, José A. Donázar, Ainara Cortés‐Avizanda, Nuria Selva, Sergio A. Lambertucci, Aishwarya Bhattacharjee, Alexis Brewer, Erin Abernethy, Olin E. Rhodes Jr., Kelsey Turner, James C. Beasley, Travis L. Devault, Andrés Ordiz, Camilla Wikenros, Barbara Zimmermann, Petter Wabakken, Christopher C. Wilmers, Justine A. Smith, Corinne J. Kendall, Darcy Ogada, Evan R. Buechley, Ethan Frehner, Maximilian L. Allen, Heiko U. Wittmer, James R.A. Butler, Johan T. Du Toit, John Read, David Wilson, Klemen Jerina, Miha Krofel, Rich Kostecke, Richard Inger, Arockianathan Samson, Lara Naves‐Alegre, José A. Sánchez‐Zapata May 2019

Scavenging In The Anthropocene: Human Impact Drives Vertebrate Scavenger Species Richness At A Global Scale, Esther Sebastián‐González, Jomar Magalhães Barbosa, Juan M. Pérez‐García, Zebensui Morales‐Reyes, Francisco Botella, Pedro P. Olea, Patricia Mateo‐Tomás, Marcos Moleón, Fernando Hiraldo, Eneko Arrondo, José A. Donázar, Ainara Cortés‐Avizanda, Nuria Selva, Sergio A. Lambertucci, Aishwarya Bhattacharjee, Alexis Brewer, Erin Abernethy, Olin E. Rhodes Jr., Kelsey Turner, James C. Beasley, Travis L. Devault, Andrés Ordiz, Camilla Wikenros, Barbara Zimmermann, Petter Wabakken, Christopher C. Wilmers, Justine A. Smith, Corinne J. Kendall, Darcy Ogada, Evan R. Buechley, Ethan Frehner, Maximilian L. Allen, Heiko U. Wittmer, James R.A. Butler, Johan T. Du Toit, John Read, David Wilson, Klemen Jerina, Miha Krofel, Rich Kostecke, Richard Inger, Arockianathan Samson, Lara Naves‐Alegre, José A. Sánchez‐Zapata

United States Department of Agriculture Wildlife Services: Staff Publications

Understanding the distribution of biodiversity across the Earth is one of the most challenging questions in biology. Much research has been directed at explaining the species latitudinal pattern showing that communities are richer in tropical areas; however, despite decades of research, a general consensus has not yet emerged. In addition, global biodiversity patterns are being rapidly altered by human activities. Here, we aim to describe large‐scale patterns of species richness and diversity in terrestrial vertebrate scavenger (carrion‐consuming) assemblages, which provide key ecosystem functions and services. We used a worldwide dataset comprising 43 sites, where vertebrate scavenger assemblages were identified using …


The Economic Impacts Of Blackbird (Icteridae) Damage To Sunflower In The Usa, Karina Ernst, Julie Elser, George Linz, Hans Kandel, Jason Holderieath, Samantha Degroot, Steven Shwiff, Stephanie Shwiff May 2019

The Economic Impacts Of Blackbird (Icteridae) Damage To Sunflower In The Usa, Karina Ernst, Julie Elser, George Linz, Hans Kandel, Jason Holderieath, Samantha Degroot, Steven Shwiff, Stephanie Shwiff

United States Department of Agriculture Wildlife Services: Staff Publications

BACKGROUND: Blackbird (Icteridae) damage to ripening sunflower (Helianthus annuus L.) has been a persistent economic issue in the USA for the last five decades. To quantify losses, we surveyed blackbird damage from 2001 to 2013 (excluding 2004) to physiologically mature sunflower in eight states: North Dakota, South Dakota, Texas, Nebraska, Minnesota, Colorado, Kansas, and Vermont.

RESULTS:We pooled data gathered during the most recent 5 years (2009 to 2013) of the survey and found losses averaged $US2.5 million and $US11.3 million for confectionery and oilseed hybrids, respectively. Three states, North Dakota, South Dakota, and Nebraska, had sufficient acreage and bird damage …


Habitat Selection By American Beaverat Multiple Spatial Scales, Guiming Wang, Lance F. Mcclintic, Jimmy D. Taylor May 2019

Habitat Selection By American Beaverat Multiple Spatial Scales, Guiming Wang, Lance F. Mcclintic, Jimmy D. Taylor

United States Department of Agriculture Wildlife Services: Staff Publications

Background: Semiaquatic mammals require both aquatic and terrestrial habitats, particularly interfaces between the two habitats. As ecosystem engineers, American beaver (Castor canadensis) consume and fell a great amount of deciduous trees. We tested the prediction that open water and amounts of food resources, including hardwood forests (i.e., deciduous trees as the dominant form of vegetation), herbaceous and woody wetlands, and shrubs, would influence the second-order habitat selection (i.e., placing home ranges on the landscape) by American beaver, whereas the third-order habitat selection of American beaver would be associated with woody wetland and shrub edges. We investigated hierarchical habitat selection by …


Hsv-1 Live-Attenuated Vaccine Strain Vc2 Confers Complete Protection In Mice Against Ocular Immunipathogenesis By The Human Clinical Strain Hsv-1 (Mckrae), Shan Krishnan Naidu May 2019

Hsv-1 Live-Attenuated Vaccine Strain Vc2 Confers Complete Protection In Mice Against Ocular Immunipathogenesis By The Human Clinical Strain Hsv-1 (Mckrae), Shan Krishnan Naidu

LSU Doctoral Dissertations

Herpes simplex virus type-1 (HSV-1) can cause severe ocular infection and blindness. We have previously shown that the HSV-1 VC2 vaccine strain is protective in mice and guinea pigs against genital herpes infection following vaginal challenge with HSV-1 or HSV-2. In this study, we evaluated the efficacy of VC2 intramuscular vaccination in mice against herpetic keratitis following ocular challenge with the lethal human clinical strain HSV-1(McKrae). VC2 vaccination in mice produced superior protection and morbidity control in comparison to its parental strain HSV-1(F). Specifically, after HSV-1(McKrae) ocular challenge, all VC2- vaccinated mice survived, while 30% of the HSV-1(F)- vaccinated and …


Epidemic Growth Rates And Host Movement Patterns Shape Management Performance For Pathogen Spillover At The Wildlife–Livestock Interface, Kezia R. Manlove, Laura M. Sampson, Benny Borremans, E. Frances Cassirer, Ryan S. Miller, Kim M. Pepin, Thomas E. Besser, Paul C. Cross May 2019

Epidemic Growth Rates And Host Movement Patterns Shape Management Performance For Pathogen Spillover At The Wildlife–Livestock Interface, Kezia R. Manlove, Laura M. Sampson, Benny Borremans, E. Frances Cassirer, Ryan S. Miller, Kim M. Pepin, Thomas E. Besser, Paul C. Cross

United States Department of Agriculture Wildlife Services: Staff Publications

Managing pathogen spillover at the wildlife–livestock interface is a key step towards improving global animal health, food security and wildlife conservation. However, predicting the effectiveness of management actions across host–pathogen systems with different life histories is an on-going challenge since data on intervention effectiveness are expensive to collect and results are system-specific.We developed a simulation model to explore how the efficacies of different management strategies vary according to host movement patterns and epidemic growth rates. The model suggested that fast-growing, fast-moving epidemics like avian influenza were best-managed with actions like biosecurity or containment, which limited and localized overall spillover risk. …


Geospatial Analysis Of Rickettsial Species, Amy Frank May 2019

Geospatial Analysis Of Rickettsial Species, Amy Frank

Animal Science Undergraduate Honors Theses

Rickettsia species are obligate intracellular, arthropod-borne bacteria with a potential to cause multiple diseases including Rocky Mountain spotted fever (RMSF). Fleas, mites, and ticks serve as vectors for Rickettsia, but ticks are the primary vector of interest. RMSF and other rickettsial diseases have continued to gain importance in both human and veterinary medicine as RMSF is the most common tick-borne disease within the United States according to the Lyme and Tick-Borne Disease Research Center. A statewide citizen science project was utilized to determine the prevalence of Spotted Fever Group (SFG) Rickettsia in Arkansas. This project yielded results in 64 …


A Review Of Osteoarthritis, Madelin Brooke Session May 2019

A Review Of Osteoarthritis, Madelin Brooke Session

Undergraduate Honors Capstone Projects

Osteoarthritis is a degenerative joint disease which plagues many older animals and humans. It is a disease that is characterized by the degeneration of joint cartilage, inflammation, as well as chronic pain and stiffness that results from this disorder. Unfortunately, most of the treatments for this painful and chronic disease mostly involve pain management and temporary relief strategies. These strategies usually include pain medication, non-steroidal anti-inflammatory drugs, injectable lubricants, as well as surgical techniques. However, because these treatments are just temporary fixes meant for pain management and to improve quality of life they must continue throughout the remainder of the …


Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters May 2019

Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters

Undergraduate Honors Capstone Projects

It has previously been shown that young, cycling ovarian transplantation in aged female mice increased the general health and life span in regard to their post-reproductive health. It has further been hypothesized that this enhancement of health is directly influenced by the ovarian somatic cells. To address this hypothesis, transplants of young germ cell depleted and germ cell containing ovaries were performed on female mice. The purpose of this study is to continue to discern the reproductive influence on aging health, specifically in the area of immunological well-being. Control group mice were separated by age and treatment mice were subsequently …


Preparation And Evaluation Of Single-Stranded Dna Aptamer-Based Immunological Adjuvant In Broiler Chickens, Adil Sabr Al-Ogaili May 2019

Preparation And Evaluation Of Single-Stranded Dna Aptamer-Based Immunological Adjuvant In Broiler Chickens, Adil Sabr Al-Ogaili

Graduate Theses and Dissertations

Mineral oils and metal salts are commonly used as adjuvants to enhance acquired immunity. Recently, monoclonal antibodies (MAbs) and recombinant peptides agonist CD40 receptor have shown remarkable promise for induction of rapid and robust immune responses. Limitations of this approach MAb production costs and multiple administrations due to anti-MAb immune responses. Here we demonstrate the development of a unique and sophisticated DNA aptamer-based alternative for CD40-directed delivery of universal antigens as an alternative in chickens, and potentially other vertebrate species. This receptor, expressed by antigen-presenting cells, acts as a costimulatory molecule for activated T helper lymphocytes. After initially selecting for …


Evaluation Of Casein Hydrolysate As An Alternative Dry-Off Treatment And Milk Quality Management Tool In Dairy Cows, Justine Elena Britten May 2019

Evaluation Of Casein Hydrolysate As An Alternative Dry-Off Treatment And Milk Quality Management Tool In Dairy Cows, Justine Elena Britten

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Mastitis, an infection of the mammary gland, is the most common and expensive animal health problem for the dairy industry and affects every dairy farm to some degree. This disease complex is painful for dairy cows, increases the on-farm use of antibiotics, presents a threat to milk quality and is a waste of time, money and milk production. Each year, the dairy industry loses as much as a billion dollars to mastitis.

Many cows will experience mastitis at least once during a lactation cycle and some animals will develop recurring mastitis episodes in a single mammary quarter. These mastitic quarters …


Male Reproductive Infection And Sexual Transmission Of Zika Virus In An Immunocompromised Mouse Model, Chad S. Clancy May 2019

Male Reproductive Infection And Sexual Transmission Of Zika Virus In An Immunocompromised Mouse Model, Chad S. Clancy

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Zika virus (ZIKV) is a sexually transmitted viral infection most frequently transmitted by mosquitoes. The source of infectious virions in the male reproductive tract has yet to be elucidated. The goals of the studies included developing and characterizing two mouse models for reproductive transmission studies and demonstration of sexual transmission of virus via artificial insemination. The mouse strains used in the study lacked receptors to interferon molecules, key signaling proteins of the host immune response. Inflammation severity was assessed during acute disease, 5-11 days after infection using a novel histopathology grading system. ZIKV proteins and genome were initially detected in …


Systematic Review Of Gastrointestinal Nematodes Of Horses From Australia, Muhammad A. Saeed, Ian Beveridge, Ghazanfar Abbas, Anne Beasley, Jenni Bauquier, Edwina Wilkes, Caroline Jacobson, Kris J. Hughes, Charles El-Hage, Ryan O'Handley, John Hurley, Lucy Cudmore, Peter Carrigan, Lisa Walter, Brett Tennent-Brown, Martin K. Nielsen, Abdul Jabbar Apr 2019

Systematic Review Of Gastrointestinal Nematodes Of Horses From Australia, Muhammad A. Saeed, Ian Beveridge, Ghazanfar Abbas, Anne Beasley, Jenni Bauquier, Edwina Wilkes, Caroline Jacobson, Kris J. Hughes, Charles El-Hage, Ryan O'Handley, John Hurley, Lucy Cudmore, Peter Carrigan, Lisa Walter, Brett Tennent-Brown, Martin K. Nielsen, Abdul Jabbar

Maxwell H. Gluck Equine Research Center Faculty Publications

Background: Equine gastrointestinal nematodes (GINs) have been the subject of intermittent studies in Australia over the past few decades. However, comprehensive information on the epidemiology of equine GINs, the efficacy of available anthelmintic drugs and the prevalence of anthelmintic resistance (AR) in Australasia is lacking. Herein, we have systematically reviewed existing knowledge on the horse GINs recorded in Australia, and main aspects of their pathogeneses, epidemiology, diagnoses, treatment and control.

Methods: Six electronic databases were searched for publications on GINs of Australian horses that met our inclusion criteria for the systematic review. Subsets of publications were subjected to review epidemiology, …


Development And Evaluation Of A One-Step Multiplex Real-Time Taqman® Rt-Qpcr Assay For The Detection And Genotyping Of Equine G3 And G14 Rotaviruses In Fecal Samples, Mariano Carossino, Maria E. Barrandeguy, Erdal Erol, Yanqiu Li, Udeni B. R. Balasuriya Apr 2019

Development And Evaluation Of A One-Step Multiplex Real-Time Taqman® Rt-Qpcr Assay For The Detection And Genotyping Of Equine G3 And G14 Rotaviruses In Fecal Samples, Mariano Carossino, Maria E. Barrandeguy, Erdal Erol, Yanqiu Li, Udeni B. R. Balasuriya

Veterinary Science Faculty Publications

Background: Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and has a negative impact on equine breeding enterprises worldwide. Among ERVA strains infecting foals, the genotypes G3P[12] and G14P[12] are the most prevalent, while infections by strains with other genomic arrangements are infrequent. The identification of circulating strains of ERVA is critical for diagnostic and surveillance purposes, as well as to understand their molecular epidemiology. Current genotyping methods available for ERVA and rotaviruses affecting other animal species rely on Sanger sequencing and are significantly time-consuming, costly and labor intensive. Here, we developed the first one-step …


Board Invited Review: Prospects For Improving Management Of Animal Disease Introductions Using Disease-Dynamic Models, Ryan S. Miller, Kim M. Pepin Apr 2019

Board Invited Review: Prospects For Improving Management Of Animal Disease Introductions Using Disease-Dynamic Models, Ryan S. Miller, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Management and policy decisions are continually made to mitigate disease introductions in animal populations despite often limited surveillance data or knowledge of disease transmission processes. Science-based management is broadly recognized as leading to more effective decisions yet application of models to actively guide disease surveillance and mitigate risks remains limited. Disease-dynamic models are an efficient method of providing information for management decisions because of their ability to integrate and evaluate multiple, complex processes simultaneously while accounting for uncertainty common in animal diseases. Here we review disease introduction pathways and transmission processes crucial for informing disease management and models at the …