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Full-Text Articles in Veterinary Medicine
Pathological And Immunohistochemical Changes In The Liver Of Monocrotaline-Treated Rats, Şevket Soylu, Aydin Çevi̇k, Necati̇ Ti̇murkaan
Pathological And Immunohistochemical Changes In The Liver Of Monocrotaline-Treated Rats, Şevket Soylu, Aydin Çevi̇k, Necati̇ Ti̇murkaan
Turkish Journal of Veterinary & Animal Sciences
Pathological and immunohistochemical changes in livers were investigated in monocrotaline-treated rats. Eighty adult-male Wistar rats were distributed in 5 groups, each containing 16 animals according to monocrotaline dose (Group I: 50 mg/kg, Group II: 100 mg/kg, Group III: 150 mg/kg, and Group IV: 200 mg/kg). The control group was administered with physiological saline. Half of the animals in each group were euthanized at the 18th hour while the remaining half at the 6th week postinoculation. At the end of the 18th hour, the most prominent lesion was hepatocytic apoptosis which was dose-dependent. Apoptotic cells were mostly located in periportal and …
The Effect Of The Metabolic Syndrome On The Histological Structure Of The Testes Tissue And The Sperm Morphology In The Rats, Ayşe Alkandurur, Şadi̇ye Kum
The Effect Of The Metabolic Syndrome On The Histological Structure Of The Testes Tissue And The Sperm Morphology In The Rats, Ayşe Alkandurur, Şadi̇ye Kum
Turkish Journal of Veterinary & Animal Sciences
In this study, we aimed to investigate the effect of metabolic syndrome on spermatozoon morphology and histological, histochemical, histomorphometric changes in the testes. Twenty-four male Sprague Dawley rats (60 day-olds) were used for this purpose. The rats in the control group were fed only water and rat food, while the rats in the experimental group were fed with water containing 20% D-fructose and rats food for 16 weeks with ad libitum. At the end of the experimental period, the testes and epididymis of the rats were removed. The testes were embedded in paraffin by performing the necessary histological procedure. In …
Chemical Castration Using An Intratesticular Injection Of Mannitol: A Preliminary Studyin A Rat Model, Mohammad-Ali Maadi, Mehdi Behfar, Amir Rasaei, Ali Shalizar-Jalali, Gholamreza Najafi, Vahid Mohammadi
Chemical Castration Using An Intratesticular Injection Of Mannitol: A Preliminary Studyin A Rat Model, Mohammad-Ali Maadi, Mehdi Behfar, Amir Rasaei, Ali Shalizar-Jalali, Gholamreza Najafi, Vahid Mohammadi
Turkish Journal of Veterinary & Animal Sciences
This study was aimed to evaluated chemical sterilization using an intra-testicular injection of mannitol 20% in rats. Fifty male Wistar rats were divided into five groups, including 1) intact, 2) surgical castration and, 3 to 5) intra-testicular injections of normal saline, hypertonic saline, and mannitol, respectively. The baseline testosterone levels were measured. Surgical castration was performed in group 2. Intra-testicular injections were performed in groups 3, 4, and 5. On day 60, the testosterone level was evaluated. Then, sperm count, viability, motility, morphological abnormalities and DNA damage were studied. Gonadosomatic index was recorded on day 60. Serum testosterone level was …
The Effects Of Different Doses Of Diclofenac Sodium On Newborn Rat Hippocampus Exposed During The Third Trimester, Ebru Eli̇bol, Süleyman Kaplan, Gamze Altun, Abdurrahman Aksoy, Berri̇n Zuhal Altunkaynak
The Effects Of Different Doses Of Diclofenac Sodium On Newborn Rat Hippocampus Exposed During The Third Trimester, Ebru Eli̇bol, Süleyman Kaplan, Gamze Altun, Abdurrahman Aksoy, Berri̇n Zuhal Altunkaynak
Turkish Journal of Veterinary & Animal Sciences
The main aim of the present study was to examine the neurotoxic effects of prenatal exposure to varying doses of diclofenac sodium (DS) on the rat hippocampus. Twenty-eight Wistar albino adult female rats weighing 280-300 g were initially used for pregnancy. When vaginal plaques were seen in female rats, it was accepted as the 0th day of pregnancy. Female rats were divided into five main groups; pure control, saline, low dose DS (3.6 mg/kg), moderate dose DS (9 mg/kg), and high dose DS (18 mg/kg). They were exposed to these treatments during their gestation. After birth, all newborn male rats …
Evaluation Of The Effects Of Bone Morphogenetic Protein-2 On The Healing Of Bonecalvarial Defects In Ovariectomized Rats, Ela Tules Kadi̇roğlu, Fati̇h Karayürek, Mehmet Erdem Akbalik
Evaluation Of The Effects Of Bone Morphogenetic Protein-2 On The Healing Of Bonecalvarial Defects In Ovariectomized Rats, Ela Tules Kadi̇roğlu, Fati̇h Karayürek, Mehmet Erdem Akbalik
Turkish Journal of Veterinary & Animal Sciences
Bone morphogenetic proteins (BMPs) are often used with bone grafts for bone regeneration. The aim of this study was to evaluate the effect of demineralized freeze-dried bone allografts and externally applied rhBMP-2 on bone healing in experimentally generated defects in the calvarium of ovariectomized and nonovariectomized rats via histological and immunohistochemical assays. The current study was carried out on 42 female Wistar rats. After ovariectomy was performed in half of the rats, the rats were divided into three groups: control, allograft, and allograft + BMP. An experimental defect with a diameter of 4 mm was created unilaterally in the parietal …
Evaluation Of The Early Term Healing Effects Of Resveratrol On Corneal Wounds In Rats, Hati̇ce Çi̇lem Perçi̇n, Zülfükar Kadi̇r Saritaş
Evaluation Of The Early Term Healing Effects Of Resveratrol On Corneal Wounds In Rats, Hati̇ce Çi̇lem Perçi̇n, Zülfükar Kadi̇r Saritaş
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to determine the effects of resveratrol (RES) treatment on corneal wound healing. Randomly divided into 2 groups were 26-week-old male Wistar albino rats. Group 1 was the control group (C) and group 2 was the RES group. A 2-3-mm-long vertical incision was made centrally in the right cornea of each rat to the descemet membrane using loupe magnification (2.5X) and the wounds were sutured using 10/0 nylon material. In the RES group, the rats were fed 30 mg/kg/day RES via oral gavage; the C and RES groups were provided food and water ad libitum …
Immunohistochemical Expression Of Secretory Proteins In Pneumonic Rat Lungs, Enver Beytut
Immunohistochemical Expression Of Secretory Proteins In Pneumonic Rat Lungs, Enver Beytut
Turkish Journal of Veterinary & Animal Sciences
The present study evaluated the expression of secretory proteins involving surfactant proteins (SP-A, SP-B, proSP-C), Clara cell secretory protein (CCSP), and thyroid transcription factor-I (TTF-I), together with lambda light chain IgG (λ-IgG), proliferating cell nuclear antigen (PCNA), and lymphocytic phenotypes (T and B cells) in the pneumonic rat lungs. The most prominent gross lesion was severe pulmonary abscession. The lungs showed severe parenchymal destruction and necrosis encapsulated by fibrous tissue. Immunostaining for SPs displayed evident hyperplasia of type II pneumocytes. Immunoreaction to SP-A and SP-B occurred strongly on the luminal surface of type II cells, and to proSP-C in the …
The Effect Of Caffeine On Neuron Number Of Rats Exposedto 900-Mhz Electromagnetic Field, Aydin Him, Nimet Burcu Deniz, Mehmet Emi̇n Önger
The Effect Of Caffeine On Neuron Number Of Rats Exposedto 900-Mhz Electromagnetic Field, Aydin Him, Nimet Burcu Deniz, Mehmet Emi̇n Önger
Turkish Journal of Veterinary & Animal Sciences
Previous studies have shown that the electromagnetic field (EMF) emitted by cell phones decreased the number of neurons in some parts of the brain. It was also shown that caffeine protects the nerve cells. This study examines if caffeine has any effects on preventing neuron loss in rats exposed to EMF. Rats were exposed to a 900-MHz EMF for 60 min a day for 28 days. The rats that were exposed to EMF were fed 1 mg/L caffeinated water instead of tap water. The rats in the sham group were put inside the exposure chamber but were not exposed to …
Cannabinoid Receptor Type 2 Agonist Jwh-133 Deteriorates The Liver Toxicity Induced By Cypermethrin*, Hi̇dayet Tutun, Emi̇ne Baydan
Cannabinoid Receptor Type 2 Agonist Jwh-133 Deteriorates The Liver Toxicity Induced By Cypermethrin*, Hi̇dayet Tutun, Emi̇ne Baydan
Turkish Journal of Veterinary & Animal Sciences
Cannabinoid receptor 2 (CB2) has a role in the pathology of some liver diseases. Cypermethrin (CYP) is a synthetic pyrethroid insecticide used commonly for the control of pests and vectors, and for protection of foodstuffs. In this study, the involvement of CB2 in CYP-induced liver damage in rats was investigated. CYP was applied to rats orally at a dose of 125 mg/kg bw per day for 14 days. CB2 agonist JWH-133 was administered by intraperitoneal injection at a dose of 3 mg/kg bw per day for the last 4 days of CYP toxicity. JWH-133 deteriorated the liver damage induced by …
Ultrastructure Of Rat Umbilical Cord Stroma-Derived Mesenchymal Stem Cells, Ahmet Ceylan, Özge Özgenç, Korhan Altunbaş, Petek Korkusuz, Asuman Özen
Ultrastructure Of Rat Umbilical Cord Stroma-Derived Mesenchymal Stem Cells, Ahmet Ceylan, Özge Özgenç, Korhan Altunbaş, Petek Korkusuz, Asuman Özen
Turkish Journal of Veterinary & Animal Sciences
Being multipotent progenitor cells, mesenchymal stem cells continue to attract attention as a promising tool for cell-based therapy and tissue engineering. However, research on the ultrastructure of these cells is rather scarce. This study was aimed at the investigation of the transmission electron microscopic ultrastructure and morphology of mesenchymal stem cells isolated from the stroma of rat umbilical cord using the explant culture method. At the end of the third passage, some of the cells isolated from the stroma of the umbilical cord were harvested for electron microscopic examination. The remaining cells were induced for osteogenic, chondrogenic, and adipogenic differentiation. …
Effects Of Ketamine On Monoamine Neurotransmittersand Gaba In Embryonic Neurocytes From Fetal Rat, Xinran Li, Mo Liu, Yue Li, Cen Guo, Lina Li, Yanan Li, Yuxin Wang, Yiming Zhang, Li Gao
Effects Of Ketamine On Monoamine Neurotransmittersand Gaba In Embryonic Neurocytes From Fetal Rat, Xinran Li, Mo Liu, Yue Li, Cen Guo, Lina Li, Yanan Li, Yuxin Wang, Yiming Zhang, Li Gao
Turkish Journal of Veterinary & Animal Sciences
The effect of ketamine, a drug commonly used as an anesthetic, on monoaminergic neurotransmitters and GABA in neurocytes from fetal rats has not yet been elucidated. We thus decided to investigate these effects by first evaluating ketamine levels in the cerebrospinal fluid by high-performance liquid chromatography. We thus determined the concentrations of GABA, DA, NE, 5-HT, and 5-HIAA following the addition of four different concentrations of ketamine at day 7 of nerve cell culture. GABA, 5-HT, and 5-HIAA levels were increased after an initial decrease: they showed the lowest levels at 10-15 min and the highest peaks at 45-90 min, …
Effects Of Nigella Sativa And Hypericum Perforatum On Wound Healing, Mehmet Cengi̇z Han, Ali̇ Sai̇d Durmuş, Aydin Sağliyan, Ci̇han Günay, Mustafa Özkaraca, Fati̇h Mehmet Kandemi̇r, Seli̇m Çomakli, Di̇cle Firat Öztopalan
Effects Of Nigella Sativa And Hypericum Perforatum On Wound Healing, Mehmet Cengi̇z Han, Ali̇ Sai̇d Durmuş, Aydin Sağliyan, Ci̇han Günay, Mustafa Özkaraca, Fati̇h Mehmet Kandemi̇r, Seli̇m Çomakli, Di̇cle Firat Öztopalan
Turkish Journal of Veterinary & Animal Sciences
In this study, it was aimed to determine the influence of applying Nigella sativa (NS) and Hypericum perforatum (HP) on wound healing. A total of 42 female albino 2-month-old Wistar rats were randomly separated into 3 main groups. Each of these main groups was separated into two subgroups for 7- and 14-day postoperative follow-ups. A total of 84 excisional skin wounds, 5 mm in diameter, were created on the backs of the rats. Placebo cream (control group), 50% NS oil cream, and 50% HP oil cream were applied topically for the first, second, and third group, respectively. The wounds were …
Investigation Of Effects Of Fucoidan Polysaccharides Extracted From Twospecies Of Padina On The Wound-Healing Process In The Rat, Moazameh Kordjazi, Bahareh Shabanpour, Ebrahim Zabihi, Mohammad Ali Faramarzi, Hassan Ahmadi Gavlighi, Seyed Mohammad Amin Feghhi, Seyed Abbas Hosseini
Investigation Of Effects Of Fucoidan Polysaccharides Extracted From Twospecies Of Padina On The Wound-Healing Process In The Rat, Moazameh Kordjazi, Bahareh Shabanpour, Ebrahim Zabihi, Mohammad Ali Faramarzi, Hassan Ahmadi Gavlighi, Seyed Mohammad Amin Feghhi, Seyed Abbas Hosseini
Turkish Journal of Veterinary & Animal Sciences
Seaweeds contains different types of polysaccharides with high abilities. The aim of this study was to determine the potential of fucoidan polysaccharides for wound-healing properties. Fucoidans of two species of Padina (P. tetrastromatica and P. boergesenii), collected from the Persian Gulf northern coastal area, were extracted and analyzed using high-performance anion-exchange chromatography. Purified fucoidans were used to prepare a 2% topical ointment. Under aseptic conditions, two identical paravertebral full-thickness skin wounds (either by burn or excision) were made in 40 anesthetized male rats allocated into 4 groups. Either fucoidan ointments or the vehicle (ointment base) were applied to rats' wounds …
Histological Changes In The Bone Structure Induced At 12 Weeks By Experimental Administration Of Bisphosphonates, Horea Artimoniu Almaşan, Mihaela Baciut, Oana Cristina Almaşan, Simion Bran, Grigore Baciut
Histological Changes In The Bone Structure Induced At 12 Weeks By Experimental Administration Of Bisphosphonates, Horea Artimoniu Almaşan, Mihaela Baciut, Oana Cristina Almaşan, Simion Bran, Grigore Baciut
Turkish Journal of Veterinary & Animal Sciences
Histological changes in bone structure were induced at 12 weeks by experimental administration of bisphosphonates, which have been associated with osteonecrosis of the jaws. The purpose of this study was to determine the effect of local administration of bisphosphonate on bone formation in rats. Surgically created bone defects were evaluated at 12 weeks by histological examination after bisphosphonate administration. Fifteen Wistar rats that underwent surgery to create a bone defect at the right femur were divided in 3 groups: 2 experimental groups and a control group. The 1st experimental group received bisphosphonate as a single 1-mL dose into the bone …
The Protective And Therapeutic Effect Of Phenoxy-2-Methyl-2-Propionic Acid On Experimental Fatty Liver In Rats, Ümmügülsüm Gümüş, Gülbi̇n Şennazli, Utku Bakirel
The Protective And Therapeutic Effect Of Phenoxy-2-Methyl-2-Propionic Acid On Experimental Fatty Liver In Rats, Ümmügülsüm Gümüş, Gülbi̇n Şennazli, Utku Bakirel
Turkish Journal of Veterinary & Animal Sciences
In this study, the potential protective and therapeutic effect of phenoxy-2-methyl-2-propionic acid (PMPA) was investigated in rats with experimental hepatic steatosis induced by a carbon tetrachloride and paraffin liquid mixture (1:1). Forty Wistar albino rats were allocated to 4 groups with 10 rats in each. Group 1 was administered a saline solution; group 2 was administered the carbon tetrachloride and paraffin liquid mixture; group 3 was administered the carbon tetrachloride and paraffin liquid mixture and PMPA for 7 days; and in group 4, hepatic steatosis was created with the carbon tetrachloride and paraffin liquid mixture during the first 7 days, …
Immunodetection Of Insulin-Like Growth Factor Binding Proteins (Igfbps) In The Sera Of Different Animal Species, Romana Masnikosa, Ivona Baricevic, Dragana Lagundzin, Olgica Nedic
Immunodetection Of Insulin-Like Growth Factor Binding Proteins (Igfbps) In The Sera Of Different Animal Species, Romana Masnikosa, Ivona Baricevic, Dragana Lagundzin, Olgica Nedic
Turkish Journal of Veterinary & Animal Sciences
Knowledge regarding the insulin-like growth factor (IGF) system and the methods for the detection and quantitation of IGF binding proteins (IGFBPs) is greater for the human species than for other animal species. This is mainly because antibodies specifically raised against nonhuman IGFBPs are rarely commercially available. We aimed to investigate which of the antibodies directed against human IGFBPs could be used for the detection of IGFBPs present in other species. We used commercially available antibodies, raised against human IGFBP-1 through IGFBP-4, in order to recognize the corresponding IGFBPs in the sera of different animal species: human, bovine, equine, porcine, ovine, …
The Effects Of Qualitative And Quantitative Protein Malnutrition On Cecal Microbiota In Wistar Rats With Or Without Neutrophil Suppression, Hali̇l Biyik, Muharrem Balkaya, Hümeyra Ünsal, Cengi̇z Ünsal
The Effects Of Qualitative And Quantitative Protein Malnutrition On Cecal Microbiota In Wistar Rats With Or Without Neutrophil Suppression, Hali̇l Biyik, Muharrem Balkaya, Hümeyra Ünsal, Cengi̇z Ünsal
Turkish Journal of Veterinary & Animal Sciences
Gastrointestinal microbiota has been claimed to be affected by the diet consumed. In this study the effects of severe qualitative and quantitative protein malnutrition on cecal microbiota of male Wistar rats with or without neutrophil depletion were investigated. A total of 43 animals were divided randomly into 7 groups. Group I (control) was given a complete chow diet, groups II, III and IV received almost protein free (N-free) diet and groups V, VI and VII received a 20% gelatin containing diet for 35 days ad libitum. In addition, groups I, II and V were given physiologic saline, groups III and …
The Effects Of Fenfluramine On Blood And Tissue Serotonin (5-Hydroxytryptamine) Levels In Rats, İbrahi̇m Pi̇ri̇nçci̇, Ahmet Ateşşahi̇n, İzzet Karahan
The Effects Of Fenfluramine On Blood And Tissue Serotonin (5-Hydroxytryptamine) Levels In Rats, İbrahi̇m Pi̇ri̇nçci̇, Ahmet Ateşşahi̇n, İzzet Karahan
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to investigate the effect of fenfluramine (FEN) administered at single and repeated doses on brain, stomach and plasma serotonin (5-Hydroxytryptamine, 5-HT) levels in rats. FEN was injected intraperitoneally at single doses (1, 3 and 10 µmol kg^{-1}) and given orally at repeated doses (1.25, 5 and 10 mg kg^{-1}) for 21 days. The tissues and plasma samples were collected 20, 40, 80 and 160 minutes after the single dose administrations and 4 h after the last dose administration in repeated experiments. In addition, the rats treated with the dose of 1.25 mg kg^-1 were …
Effects Of Phenobarbital On Serum And Liver Paraoxonase And Arylesterase Activities In Rats, Ahmet Ateşşahi̇n, İzzet Karahan, İbrahi̇m Pi̇ri̇nçci̇, M. Feri̇t Gürsu, Funda Gülcü
Effects Of Phenobarbital On Serum And Liver Paraoxonase And Arylesterase Activities In Rats, Ahmet Ateşşahi̇n, İzzet Karahan, İbrahi̇m Pi̇ri̇nçci̇, M. Feri̇t Gürsu, Funda Gülcü
Turkish Journal of Veterinary & Animal Sciences
This study was carried out to determine the effects of phenobarbital, administered orally and intraperitoneally over different periods, on paraoxonase, arylesterase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities and total protein levels in the serum and liver. Thirty-six rats, 16-18 weeks old and weighing 240-260 g, were used. Phenobarbital was applied both orally and intraperitoneally at a dose of 100 mg/kg. Paraoxonase and arylesterase activities in serum and liver samples were measured spectrophotometrically using paraoxon and phenylasetate substrates, respectively. Although no significant changes were determined in serum paraoxonase and arylesterase activities, liver paraoxonase and arylesterase activities and total protein …
Morphometry Of The Lymph Nodes Excluding The Thoracic And Abdominal Cavity In Wistar Rats, İlknur Dabanoğlu, Hüsnü Erbay Bardakçioğlu, Fi̇gen Sevi̇l, Di̇dem Alp
Morphometry Of The Lymph Nodes Excluding The Thoracic And Abdominal Cavity In Wistar Rats, İlknur Dabanoğlu, Hüsnü Erbay Bardakçioğlu, Fi̇gen Sevi̇l, Di̇dem Alp
Turkish Journal of Veterinary & Animal Sciences
Ten male adult Wistar rats were used to obtain some measurements of the lymph nodes located in the head, neck, forelimb and hindlimb. The lymph nodes were marked by the injection of Evans Blue and were then dissected. In order to provide sufficient data for the morphometric properties of lymph nodes, the lymph nodes on each side were counted, and the longest and widest diameters of the lymph nodes were also measured. The mandibular lymph nodes were found to be higher in number in comparison with the other lymph nodes investigated. The largest was found in the axillary accessory lymph …
6-Phosphogluconate Dehydrogenase: Purification, Characterization And Kinetic Properties From Rat Erythrocytes, Şükrü Beydemi̇r, Mehmet Çi̇ftçi̇, Hayrullah Yilmaz, Ömer İrfan Küfrevi̇oğlu
6-Phosphogluconate Dehydrogenase: Purification, Characterization And Kinetic Properties From Rat Erythrocytes, Şükrü Beydemi̇r, Mehmet Çi̇ftçi̇, Hayrullah Yilmaz, Ömer İrfan Küfrevi̇oğlu
Turkish Journal of Veterinary & Animal Sciences
In this paper, a simple and rapid method for the purification of 6-phosphogluconate dehydrogenase from rat erythrocytes together with an analysis of the kinetic behavior and some properties of the enzyme are considered. The purification steps comprised high-speed centrifugation, 20-50% ammonium sulfate precipitation and 2', 5'-ADP Sepharose 4B affinity gel chromatography. The yield was 78.4% and the specific enzyme activity was 5.15 EU/mg proteins. The molecular mass of the subunit was estimated to be 59,566 Da by SDS polyacrylamide gel electrophoresis (SDS-PAGE) and native enzyme was found to be 111,000 Da by gel filtration column chromatography. The enzyme had an …
The Effects Of High Copper And Zinc On Some Hematological Parameters In Rats, Sebahat Aydemi̇r, Mukaddes Özcan
The Effects Of High Copper And Zinc On Some Hematological Parameters In Rats, Sebahat Aydemi̇r, Mukaddes Özcan
Turkish Journal of Veterinary & Animal Sciences
The effect of high levels of Zn and Cu supplemented into the diet on Zn and Cu levels in the liver, pancreas and serum, the number of red and white blood cells, hematocrit value, hemoglobin levels, superoxide dismutase (SOD) activity in red blood cells, live weight, and liver and pancreas weights were investigated. A total of 77 Wistar albino rats were used as the research material. Twelve of the rats were separated as the control group and the remaining 65 were divided into five experimental groups (D1, D2, D3, D4 and D5) with 13 rats in each. Then, 70 mg/kg/day …
Investigation On The Situation Of Free And Bound Residues On Rats Fed Chicken Liver Containing Free And Bound Aflatoxin B_1 Residues, Mehmet Özdemi̇r
Investigation On The Situation Of Free And Bound Residues On Rats Fed Chicken Liver Containing Free And Bound Aflatoxin B_1 Residues, Mehmet Özdemi̇r
Turkish Journal of Veterinary & Animal Sciences
The aim of the present study is to determine free and bound residues of 3H-aflatoxin B_1 given orally by a gavage at a single dose (1 mg/kg body weight) in the liver tissues of broilers, and to show whether they accumulate as free and bound aflatoxin B_1 residues in the tissues of liver and muscle of the rats that consumed the liver of those broilers. A total of 30 Ross PM-3 broilers and 49 male Sprague-Dawley rats were used in the study. Free aflatoxin B_1 residue in the liver tissues of the chicken treatment group after 12h was found to …
The Effect Of Zinc On Body Weight And Some Serum Enzymes In Rats, Süleyman Korkut Tekeli̇, Nezi̇r Yaşar Toker, Fatma Tekeli̇
The Effect Of Zinc On Body Weight And Some Serum Enzymes In Rats, Süleyman Korkut Tekeli̇, Nezi̇r Yaşar Toker, Fatma Tekeli̇
Turkish Journal of Veterinary & Animal Sciences
100 male Wistar albino rats were used in this study. After the adaptation period, the rats were divided into 5 equal groups. The experimental period lasted 22 days. Food and water were given ad libitum. 0 ppm, 100 ppm, 500 ppm, 1,000 ppm and 2,000 ppm zinc were given by nasogastric probe to the control, experiment-1, experiment-2, experiment-3 and experiment-4 groups respectively, on days 1, 6, 11, 16, and 21 of the experimental period. The animals were weighed and blood samples were taken on days 2, 7, 12, 17, 22 of the experimental period. AST, ALT and ALP levels in …
Morphological Adaptation Of Rat Skeletal Muscle To A Cold Environment, Fati̇me Geyi̇koğlu, Aysel Temelli̇, Abdullah Özkaral
Morphological Adaptation Of Rat Skeletal Muscle To A Cold Environment, Fati̇me Geyi̇koğlu, Aysel Temelli̇, Abdullah Özkaral
Turkish Journal of Veterinary & Animal Sciences
Male Sprague-Dawley rats (SD) were kept in medium between the postnatal 80^{th} and 130^{th} day while environmental temperature (from 20 to 5 ºC) and photoperiod were decreased gradually. The weight of the animals adapted to the cold and the weight and length of the external digitorum longus (EDL) muscle were measured. When compared with controls, in a cold environment the weight and fiber length of the muscle was reduced significantly. In addition, EDL muscle was separated into two (red and white) by using the succinic dehydrogenase (SDH) method and the percentage of fiber types and fiber diameters according to mitochondria …
Morphological And Microscopical Examination Of The Rat Brachial Plexus, Ahmet Uzun, Nureddi̇n Cengi̇z, Ahmet Kavakli, Saci̇de Karakaş
Morphological And Microscopical Examination Of The Rat Brachial Plexus, Ahmet Uzun, Nureddi̇n Cengi̇z, Ahmet Kavakli, Saci̇de Karakaş
Turkish Journal of Veterinary & Animal Sciences
The rat brachial plexus was studied morphologically and the average numbers of the fascicles were studied by light microscope. For this purpose, we used 30 Wistar albino adult rats (16 males, 14 females; 180-250 g). The rats were anaesthetized by urethane (0.6 ml/100 g body weight injected i.p.). The brachial plexus was prepared for the microdissection technique and was evaluated in terms of its formation. Sections of the origin level of roots (C_5, C_6, C_7, C_8 and Th_1) and the terminal branches (ulnar, median, radial (musculospiral), axillary (circumflex), and musculocutaneous nerves) were taken and the average numbers of fascicles were …
Antiinflammatory And Antipyretic Activity Of Polygonum Lapathifolium In Rats, Oya Keleş, Tülay Bakirel, Süleyman Şener, Handan Aydin, Keri̇m Alpinar
Antiinflammatory And Antipyretic Activity Of Polygonum Lapathifolium In Rats, Oya Keleş, Tülay Bakirel, Süleyman Şener, Handan Aydin, Keri̇m Alpinar
Turkish Journal of Veterinary & Animal Sciences
This study was conducted to evaluate the pharmacologic effects of Polygonum lapathifolium L. (Polygonaceae), growing naturally in Turkey. The antiinflammatory activity of the ethanol extract of the root and rhizome of P. lapathifolium was evaluated using carrageenan-induced paw edema in rats. Intraperitoneal pretreatment with extract at doses ranging from 100 to 500 mg/kg significantly inhibited the acute phase of this experimental model of the inflammatory process in a dose-dependent manner. At maximal dose (500 mg/kg), it exhibited a significantly higher action when compared with those of other doses and was found to be 1.08 times as active as indomethacin. The …
Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu
Epidermal Growth Factor Receptor (Egfr) Immunolocalization In The Male Rat Reproductive Tract During Pre-And Postnatal Periods, Celal Kaloğlu, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu
Turkish Journal of Veterinary & Animal Sciences
A number of recent studies suggest the effects of several growth factors as well as genetic factors on the development and differentiation of the testes and excretory ducts. One of the most important growth factors affecting the development and differentiation of the above-mentioned organs may be epidermal growth factor (EGF). Therefore, the aim of the present study was to investigate the effects of EGF on the development of the testes and excretory ducts of male rats by determining the immunolocalization of EGF receptors in these organs during foetal and postnatal periods. To do this, testicular and excretory duct tissue samples …
Lectin And Peptide Expression In Nodose, Sphenopalatine And Superiorcervical Ganglia Of The Rat, Zafer Soygüder
Lectin And Peptide Expression In Nodose, Sphenopalatine And Superiorcervical Ganglia Of The Rat, Zafer Soygüder
Turkish Journal of Veterinary & Animal Sciences
The presence and distribution of Griffonia SimplicifoliaI-B4 (GSA I-B4) and Calcitonin Gene Related Peptide (CGRP) were studied in the nodose ganglion (NG) (inferior ganglion of the vagus nerve), sphenopalatine ganglion (SPG) and superior cervical ganglion (SCG) of the rat. GSA I-B4 labeling was found in all ganglia tested. Neither SPG nor SCG cell bodies stained with CGRP were undetectable. The pattern of the distribution of GSA I-B4 and CGRP labeled cells were quite similar in the nodose ganglion. They were found in the poles of the ganglion with some marginal labeling. Large numbers of GSA I-B4 and CGRP labeled cells …
The Effect Of Ultraviolet B (Uvb) Radiation On Some Electrolytes In Rats, Mukaddes Özcan, Göknur Akin, Ülker Çöteli̇oğlu, Murat Arslan
The Effect Of Ultraviolet B (Uvb) Radiation On Some Electrolytes In Rats, Mukaddes Özcan, Göknur Akin, Ülker Çöteli̇oğlu, Murat Arslan
Turkish Journal of Veterinary & Animal Sciences
In our research, the effect of UVB radiation on the amounts of Ca^{++}, inorganic P(Pi), K^+, Na^+, Mg^{++} , Cl^- in serums of 22 week- old Wistar-Albino rats was investigated. UVB radiation was applied to trial group animals at dosages used for treatment (4 J/ cm^2) for a period of 4 weeks.The blood samples were taken before the ray application as the control group. At the end of one month there was no change in the amounts of Pi, K^+, Mg^{++} but the level of serum -Ca^{++} increased significantly (P