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Translational Medical Research Commons™
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Articles 121 - 150 of 227
Full-Text Articles in Translational Medical Research
Talking To Children About Their Terminal Disease And Ultimate Death, Alyssa Nesbitt
Talking To Children About Their Terminal Disease And Ultimate Death, Alyssa Nesbitt
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Kreicbergs U, Valdimarsdóttir U, Onelöv E, Henter J, Steineck G. Talking about death with children who have severe malignant disease. New Eng J Med. 2004;351(12):1175-1186. doi: 10.1056/nejmoa040366.
Outcomes Of Robotic-Assisted Laparoscopic Prostatectomy Versus Open Prostatectomy In Surgical Intervention Of Localized Prostate Cancer, Hojun Lee, Brandon Ahlgren
Outcomes Of Robotic-Assisted Laparoscopic Prostatectomy Versus Open Prostatectomy In Surgical Intervention Of Localized Prostate Cancer, Hojun Lee, Brandon Ahlgren
Clinical Research in Practice: The Journal of Team Hippocrates
An informed consent conversation regarding robotic-assisted laparoscopic prostatectomy versus open prostatectomy in patients with localized prostate cancer.
Evidence Doesn’T Change Prescribing Patterns…So What Does?, Ali Rida, Anthony Brooks
Evidence Doesn’T Change Prescribing Patterns…So What Does?, Ali Rida, Anthony Brooks
Clinical Research in Practice: The Journal of Team Hippocrates
The authors write in support of critical analysis of clinical research, as a corrective to the physician's urge to "do something" even when no evidence of benefit exists.
Empiric Antibiotic Use For Infectious Conjunctivitis Provides Little Clinical Benefit, Matthew M. Rolain
Empiric Antibiotic Use For Infectious Conjunctivitis Provides Little Clinical Benefit, Matthew M. Rolain
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Rose PW, Harnden A, Brueggemann AB, et al. Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial. Lancet. 2005;366(9479):37-43. doi: 10.1016/S0140-6736(05)66709-8.
Bisphosphonates Can Be Safely Given To Patients With Hypercalcemia And Renal Insufficiency Secondary To Multiple Myeloma, Matthew J. Miller
Bisphosphonates Can Be Safely Given To Patients With Hypercalcemia And Renal Insufficiency Secondary To Multiple Myeloma, Matthew J. Miller
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Itou K, Fukuyama T, Sasabuchi Y, et al. Safety and efficacy of oral rehydration therapy until 2 h before surgery: a multicenter randomized controlled trial. Journal of Anesthesia. 2012;26(1):20-27. doi: 10.1007/s00540-011-1261-x.
Social Inequity Is A Life And Death Situation For Our Patients, Stephanie Clough, Mira Hamame, Elizabeth Bavers
Social Inequity Is A Life And Death Situation For Our Patients, Stephanie Clough, Mira Hamame, Elizabeth Bavers
Clinical Research in Practice: The Journal of Team Hippocrates
Advocating for change in the economic structure of health care in the United States is a moral imperative.
My First Experience Using Clinical Evidence To Change Patient Care, Alec Aiello
My First Experience Using Clinical Evidence To Change Patient Care, Alec Aiello
Clinical Research in Practice: The Journal of Team Hippocrates
This third year medical student reflects upon how his observations and subsequent research into a clinical question was able to influence the way his team thought about administering care in their day-to-day practice.
Npo Or Ama? Patients Allowed Clear Liquids Up To 2 Hours Pre-Procedure Have Equivalent Aspiration Risk And Increased Patient Satisfaction, Erich Smith
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Itou K, Fukuyama T, Sasabuchi Y, et al. Safety and efficacy of oral rehydration therapy until 2 h before surgery: a multicenter randomized controlled trial. Journal of Anesthesia. 2012;26(1):20-27. doi: 10.1007/s00540-011-1261-x.
Icatibant Is Not Helpful For The Treatment Of Ace Inhibitor-Induced Angioedema, Samantha R. Schwartz
Icatibant Is Not Helpful For The Treatment Of Ace Inhibitor-Induced Angioedema, Samantha R. Schwartz
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Sinert R, Levy P, Bernstein JA, et al. Randomized trial of icatibant for angiotensin-converting enzyme inhibitor-induced upper airway angioedema. J Allergy Clin Immunol Pract. 2017; 5(5): 1402-1409. doi: 10.1016/j.jaip.2017.03.003.
Renal Angioplasty Does Not Improve Clinical Outcomes Compared To Standard Medical Therapy In Patients With Atherosclerotic Renal Artery Stenosis, Alexandra Morris
Renal Angioplasty Does Not Improve Clinical Outcomes Compared To Standard Medical Therapy In Patients With Atherosclerotic Renal Artery Stenosis, Alexandra Morris
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Cooper CJ, Murphy T, Cutlip D, Jamerson K, Henrich W. Stenting and medical therapy for atherosclerotic renal-artery stenosis. New Eng J Med. 2014;370(1):13-22. doi: 10.1056/NEJMoa1310753.
Early Dexamethasone Administration In Adults With Suspected Meningitis Lowers Morbidity And Mortality, Dana Siegel
Early Dexamethasone Administration In Adults With Suspected Meningitis Lowers Morbidity And Mortality, Dana Siegel
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of de Gans J, van de Beek D, Investigators EDiABMS. Dexamethasone in adults with bacterial meningitis. New Eng J Med. 2002;347(20):1549-1556. doi: 10.1056/NEJMoa021334.
Memantine Unproven To Provide Any Clinical Benefit In Cases Of Vascular Cognitive Impairment, Irene Kitromelides
Memantine Unproven To Provide Any Clinical Benefit In Cases Of Vascular Cognitive Impairment, Irene Kitromelides
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Wilcock G, Möbius HJ, Stöffler A. A double-blind, placebo-controlled multicentre study of memantine in mild to moderate vascular dementia (MMM500). Int Clin Psychopharmacol. 2002 Nov;17(6):297-305. doi: 10.1097/00004850-200211000-00005.
Roflumilast Does Not Decrease Copd Exacerbations In Adequately Treated Patients, But Subgroup Analysis Allows For Shared Decision Making, Nathanael Sanchez
Roflumilast Does Not Decrease Copd Exacerbations In Adequately Treated Patients, But Subgroup Analysis Allows For Shared Decision Making, Nathanael Sanchez
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Martinez FJ, Rabe KF, Sethi S, et al. Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting beta2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial. Am J Respir Crit Care Med. Sep 1 2016;194(5):559-567. doi: 10.1164/rccm.201607-1349OC.
Confirmation Bias By Consumers Of Clinical Research Demonstrates The Need For Implementation Science, James Peter Meza
Confirmation Bias By Consumers Of Clinical Research Demonstrates The Need For Implementation Science, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The Journal's Editor holds that, although Evidence-based medicine typically only looks for bias of the research design, still evidence-based practice must also include the biases of those using the research evidence and how it is deployed in clinical practice.
Non-St-Segment Elevation Acute Coronary Syndrome: Early Versus Delayed Cardiac Catheterization, Teresa Colelli, Adrianna Clapp, Rudy Wenner, Blake J. Arthurs
Non-St-Segment Elevation Acute Coronary Syndrome: Early Versus Delayed Cardiac Catheterization, Teresa Colelli, Adrianna Clapp, Rudy Wenner, Blake J. Arthurs
Clinical Research in Practice: The Journal of Team Hippocrates
An informed consent conversation regarding early vs. delayed cardiac catheterization for patients with NSTEMI.
Editorial: Clinical Practice Can Save Evidence-Based Medicine From Itself, James Peter Meza, Nicholus Yee
Editorial: Clinical Practice Can Save Evidence-Based Medicine From Itself, James Peter Meza, Nicholus Yee
Clinical Research in Practice: The Journal of Team Hippocrates
Although imperfect, the structure of this journal and its publications are demonstrations of clinicians attempting to actualize the wisdom of these foundational thinkers. We need to leave examples and guideposts to the next generation of clinicians of how to fulfill this vision of being excellent clinicians, through both formal education and role modeling.
Pneumatic Balloon Dilation Versus Myotomy For The Treatment Of Achalsia, Benjamin E. Ueberroth
Pneumatic Balloon Dilation Versus Myotomy For The Treatment Of Achalsia, Benjamin E. Ueberroth
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Moonen A, Annese V, Belmans A, et al. Long-term results of the European achalasia trial: A multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. Gut. 2016 May;65(5):732-9. doi: 10.1136/gutjnl-2015-310602.
Fecal Transplant Is Superior To Oral Vancomycin For Treatment Of Recurrent Clostridium Difficile, Kassandra J. Weber
Fecal Transplant Is Superior To Oral Vancomycin For Treatment Of Recurrent Clostridium Difficile, Kassandra J. Weber
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013;368(5):407-415. doi: 10.1056/NEJMoa1205037.
Equal Efficacy Of Clopidogrel Versus Ticagrelor As Monotherapy In Peripheral Artery Disease, Aimee L. Vos
Equal Efficacy Of Clopidogrel Versus Ticagrelor As Monotherapy In Peripheral Artery Disease, Aimee L. Vos
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Hiatt H, Fowkes G, Heizer G, et al. Ticagrelor versus clopidogrel in symptomatic peripheral artery disease. N Engl J Med. 2017;376:32-40. doi: 10.1056/NEJMoa1611688.
Lurasidone Is Not Associated With Risk Of Qtc Prolongation, Halimah Y. Oral
Lurasidone Is Not Associated With Risk Of Qtc Prolongation, Halimah Y. Oral
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Meltzer HY, Cucchiaro J, Silva R, Ogasa M, Phillips D, Xu J, Kalali AH, Scheizer E, Pikalov A, Loebel A. Lurasidone in the treatment of schizophrenia: a randomized, double-blind, placebo- and olanzapine-controlled study. Am J Psychiatry. 2011 Sep;168(9):957-67. doi: https://doi.org/10.1176/appi.ajp.2011.10060907.
Long-Term Antibiotic Therapy Is Just As Effective As Amputation For Foot Osteomyelitis In Diabetics Without Peripheral Arterial Disease, Christopher Hopper
Long-Term Antibiotic Therapy Is Just As Effective As Amputation For Foot Osteomyelitis In Diabetics Without Peripheral Arterial Disease, Christopher Hopper
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Lázaro-Martínez JL, Aragón-Sánchez J, García-Morales E. Antibiotics versus conservative surgery for treating diabetic foot osteomyelitis: a randomized comparative trial. Diabetes Care. 2014;37(3):789-95. doi: 10.2337/dc13-1526.
Ssri Maintenance Therapy Reduces Rate Of Recurrence For Elderly Patients With First Episode Of Major Depression, Blake J. Arthurs
Ssri Maintenance Therapy Reduces Rate Of Recurrence For Elderly Patients With First Episode Of Major Depression, Blake J. Arthurs
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Reynolds CF 3rd, Dew MA, Pollock BG, et al. Maintenance treatment of major depression in old age. N Engl J Med. 2006 Mar 16;354(11):1130-8. doi: 10.1056/NEJMoa052619. Based on the appraisal, long term SSRI maintenance therapy is recommended for elderly patients suffering from first episode of major depression.
My Patient Chose To Not Use Daily Azithromycin To Prevent Exacerbation Of Copd, Jacob Oblak
My Patient Chose To Not Use Daily Azithromycin To Prevent Exacerbation Of Copd, Jacob Oblak
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Albert RK, Connett J, Bailey WC, et al. Azithromycin for prevention of exacerbations of COPD. New Eng J Med. 2011;365:689-698. doi: 10.1056/NEJMoa1104623.
Abstinence From Alcohol Improves Survival In Decompensated Cirrhotic Patients, Perry Zong
Abstinence From Alcohol Improves Survival In Decompensated Cirrhotic Patients, Perry Zong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Alvarez MA, Cirera I, Solà R, Bargalló A, Morillas RM, Planas R. Long-term clinical course of decompensated alcoholic cirrhosis. Journal of Clinical Gastroenterology. 2011;45(10):906-911. doi: 10.1097/mcg.0b013e3182284e13.
Therapeutic Hypothermia For Children After In-Hospital Cardiac Arrest Not Helpful, Bradley Kolb
Therapeutic Hypothermia For Children After In-Hospital Cardiac Arrest Not Helpful, Bradley Kolb
Clinical Research in Practice: The Journal of Team Hippocrates
An informed consent discussion regarding the merits of therapeutic hypothermia in a comatose pediatric patient following in-hospital cardiac arrest and return of spontaneous circulation.
Institutional Protocols Can Improve Ivc Filter Retrieval Rates, Madeline Ross, Gong He, Veronica Santana-Ufret, Anjali Sundar
Institutional Protocols Can Improve Ivc Filter Retrieval Rates, Madeline Ross, Gong He, Veronica Santana-Ufret, Anjali Sundar
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Lynch FC. A method for following patients with retrievable inferior vena cava filters: results and lessons learned from the first 1100 patients. J Vasc Interv Radiol. 2011;22:1507–1512. doi: 10.1016/j.jvir.2011.07.019
Autologous Blood Patch After Ct-Guided Lung Biopsy Might Reduce Pneumothorax Requiring Chest Tube Placement, Tiffani Strickland
Autologous Blood Patch After Ct-Guided Lung Biopsy Might Reduce Pneumothorax Requiring Chest Tube Placement, Tiffani Strickland
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Malone LJ, Stanfill RM, Wang H, Fahey KM, Bertino RE. Effect of intraparenchymal blood patch on rates of pneumothorax and pneumothorax requiring chest tube placement after percutaneous lung biopsy. American Journal of Roentgenology. 2013;200(6):1238-1243. doi: 10.2214/ajr.12.8980.
Icatibant Is Not An Appropriate Treatment Option For Ace-Inhibitor Induced Angioedema Of The Head And Neck, Faiz Khaja
Icatibant Is Not An Appropriate Treatment Option For Ace-Inhibitor Induced Angioedema Of The Head And Neck, Faiz Khaja
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Sinert T, Levy P, Bernstein JA, et al. Randomized trial of icatibant for angiotensin-converting enzyme inhibitor-induced upper airway angioedema. J Allergy Clin Immunol Pract. 2017;5(5):1402-9. doi: 10.1016/j.jaip.2017.03.003
Anidulafungin: A Noninferior Alternative To Fluconazole For Treatment Of Esophageal Candidiasis, Blake S. Sanford
Anidulafungin: A Noninferior Alternative To Fluconazole For Treatment Of Esophageal Candidiasis, Blake S. Sanford
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Krause DS, Simjee AE, van Rensburg C, et al. A randomized, double-blind trial of anidulafungin versus fluconazole for the treatment of esophageal candidiasis. Clin Infect Dis. 2004;39(6):770-775. doi: 10.1086/423378.
Sertraline Is An Effective Management Option For Cholestatic Pruritus, Rudy W. Wenner
Sertraline Is An Effective Management Option For Cholestatic Pruritus, Rudy W. Wenner
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Mayo MJ, Handem I, Saldana S, Jacobe H, Getachew Y, Rush AJ. Sertraline as a first-line treatment for cholestatic pruritus. Hepatology. 2007 Mar;45(3):666-74. doi: 10.1002/hep.21553