Translational Medical Research Commons^™

Improving Functional Electrical Stimulation Prescription For Persons With Multiple Sclerosis: A Case Series, Kurt Jackson

Thomas C. Hunt Building a Research Community Day

Purpose: Despite a growing body of evidence supporting the use of functional electrical stimulation (FES) in persons with MS (PwMS), prescription remains a highly individualized process with no well-established guidelines for assessing the immediate or long-term effects to ensure maximum benefit.  The purpose of this case series was to assess the feasibility and benefits of using wearable sensors and video analysis to provide immediate feedback on gait performance, when using lower leg and thigh stimulation individually or in combination, to improve FES prescription.

Subjects: 3 adults with multiple sclerosis (MS) with varying levels of gait dysfunction.

Methods: During …

Transcranial Magnetic Stimulation As A Treatment Modality For Functional Bowel Disorder And Irritable Bowel Syndrome And Possible Correlations With The Gut-Brain Axis: A Review, Lauren Draper, Devin Pfister, Ethan Zaugg

Annual Research Symposium

Functional Bowel Disorders (FBD), including Irritable Bowel Syndrome (IBS), are highly prevalent gastrointestinal conditions classified as Disorders of Gut-Brain Interactions (DGBIs) under the Rome IV criteria. These conditions, marked by abdominal pain, altered bowel habits, and significant psychological comorbidities, present substantial challenges in both diagnosis and treatment. Conventional therapies primarily target gut-centric mechanisms but often yield limited efficacy, underscoring the need for approaches that account for the complex interplay of the gut-brain axis in DGBI pathophysiology.

The Effect Of Arm Swing On Countermovement Vertical Jump Performance, Arash Mohammadzadeh Gonabadi

UNO Student Research and Creative Activity Fair

Vertical jumping is one of the popular ways to evaluate ankle-knee efficiency in athletic population. Arm swing can play a crucial role in enhancing vertical jump performance. This study aimed to address the differences in kinetic and kinematic parameters during countermovement jump motion with arm swing (AS) and no arm swing (NAS). We used OpenSim to examine the efficacy of AS in reducing the impulse applied to the body and changes in range of lower limb joint angles at landing instant. We calculated the maximum vertical peak of the ground reaction force and impulse generated at landing in two different …

Flow-Induced Dilation Of Skeletal Muscle Feed Arteries: Relevance To Exercise Hyperemia, Brittni N. Moore, Jeffrey J. Jasperse Dr.

Seaver College Research And Scholarly Achievement Symposium

During exercise, an increase in blood flow to working skeletal muscle is necessary in order to sustain activity for longer than a few seconds. This is accomplished by the dilation of arteries and arterioles feeding the muscle. Arterioles, located within contracting muscle, are exposed to dilatory metabolites released by the muscle; however, the mechanism by which feed arteries dilate is still unknown, since they are located external to the muscle. The purpose of this study was to determine if flow-induced dilation (resulting from shear stress on endothelial cells) contributes to exercise hyperemia in rat extensor digitorum longus and gastrocnemius muscle …